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Homeostasis
300 Biology
2015
Ms Gibellini
Introduction Videos
 http://www.johnwil
ey.net.au/highered/
interactions/media/
Energy/content/Ene
rgy/met6a/frameset
.htm
 http://www.physiol
ogycentre.com/ther
moregulation-
student.html
Homeostasis
 ________________- body’s ability to maintain a constant internal
environment.
 Required for proper functioning of the body because the
______________ that control all metabolic activity essential for life,
are very sensitive to changes in their environment.
 Thus constant state must be maintained in spite of changing the
____________________________.
Balancing Act
The following factors need to be kept in balance:
 Body temperature
 Water (osmotic pressure)
 Blood sugar
 Carbon dioxide concentration
 Oxygen concentration
 pH
 Mineral salts
Negative Feedback
 When a condition in the body changes from the norm, a __________is sent
to a control center (usually the _____________ in the brain).
 The control center then instructs _____________ (_________________) to
respond and _____________ the change.
 The control center then _________________ a change in temperature as a
result of the ________________, it then sends a message to
_______________ the response or stop it all together if temperatures have
returned to ______________
 Works in the ______________ direction to the stimulus hence
_________________,
 eg you are hot from running, so brain tells your body to sweat to cool you
down. Once you are cool your brain tells your body to stop or slow down
sweating.
Negative Feedback Loop
Adaptive Advantage
 Organisms can _________to the changing environments and therefore occupy
___________________, hence reducing ______________
 The more advanced an animal’s ________________ systems, the greater its
chance of ______________with a changing environment = survival of organism
 If _______________ processes can continue despite a _________________
environment, an organism is able to inhabit a wider range of habitats and
_____________ more successfully to maintain its population. = survival of species
Why Regulate Heat?
 Chemical reactions occurring in cells are very ___________
 _____________ that control cellular activity are heat-
sensitive
 Many _________________can only function properly if
they float freely in the lipid bilayer, which is only possible
if it is liquid; at low temperature the bilayer ___________.
 At around 85ºC, the ________________holding the two
strands of __________ together break, causing it to become
single stranded.
Why Regulate Heat
 Enables mammals to successfully live in a wider variety of
habitats – reduces ______________________
 Always ready for _____________; can be active at a variety of
times of day and night
 Their __________ capacity is many times that of cold blooded
animals
 Not greatly affected by __________temperatures.
 Muscles provide ___________ power; capable of sustained
high activity.
How We Lose and Gain Heat
 Body temperature is affected by the ____________, amount of
_________ (____________________________), BMI, illness, hydration,
______________
 Heat can be gained or lost from any place where the body is in
______________ with the environment (skin and lungs)
 Heat can be gained or lost by:
 Conduction
 Convection
 Radiation
 Evaporation
How is Temperature Monitored?
 The _______________ in the brain monitors the
temperature of the __________ flowing through
it
 This is called the _____________________as it
is sensing temperature at the _______ of the
body.
 The hypothalamus receives information regarding
changes in external temperature from
__________________
 There are two types of receptors, hot and cold.
 ______________relay the messages to and from
receptors and the hypothalamus and effector cells
Too Hot?
Nervous impulses send messages:
to the _____________ glands which start to sweat in
order to lower the body temperature through evaporation,
______________to lose heat through conduction
breathing rate ____________(brings more cooler air into
body)
____________lowering skin hairs letting more air flow
across skin to lose heat by convection and evaporation -
No ___________
Behavioral responses
Metabolic rate __________
Sweating
 When you are hot, ________________are stimulated
to release sweat.
 Heat energy from your skin is used to turn the liquid
sweat into gas - sweat ______________
 Because heat is lost, your___________ cools down as
does the _________ flowing past
 Deep in the dermis are supplied by sympathetic nerve fibres.
 In humans most sweat glands are eccrine glands and secrete a
dilute salt solution.
 Sweat doesn’t work in a humid environment
 Environmental temperature > body temp for sweating to be
effective
Vasodilation
 Your blood carries most of the heat energy in your body.
 There are small blood vessels called ___________ just underneath
your skin.
 When you are hot, these capillaries get___________(dilate) so
more blood comes close to the surface of the skin and heat is lost.
 This is why some people go _________when they are hot!
If the temperature
rises, the blood
vessel dilates (gets
bigger).
This means more heat is lost from the surface of the skin
Metabolic Rate
 The ___________________changes through a reduction in the
secretion of thyroxine
 This results in a ____________ in metabolic rate
 The decrease in metabolic rate causes _____________to be produced
in the body
Behavioural Responses
We change our behavioural responses by:
 _____________(decreasing activity)
 staying in the shade
 _______________________
 wearing less clothing
 ________________
 Submerging body in cold water
 _____________________
 Fanning ourselves
Chicks seek shade.
When the system fails…
 If the body cannot lower its temperature it goes into a
_____________ STATE
 Resulting in heat exhaustion ______________
 Resulting in heat stroke over _____________
 Often dehydration also occurs at the same time
________________
 Red skin, no sweating, fever, disorientation, pinpoint pupils, shallow
breathing
_______________
 Cooling blood and constricting blood vessels by submersing body in ice water
 Stretch body out to increase surface area in contact with cool air
 Move into shade
 Remove clothing
 Give cold fluids
 Ice packs/wet towels
Fever
 This is usually associated with _______________.
 The immune system produces fever-inducing chemicals called
_____________, which travel through the blood to the
hypothalamus, where they trick it into raising the body
temperature.
 ________________________lower temperature by blocking the
production of pyrogens.
 Apply cold wet clothes
 Remove clothing
 Seek medical care to treat infection – antibiotics for bacterial
infections
If left un treated person can have
___________________________.
High Temp
24 of 12 © Boardworks Ltd 2009
Thermoregulation in endotherms
Endotherms generate most of their heat metabolically.
As they are warmer than their environment they tend to
lose body heat to their surroundings.
Adaptations for heat conservation include:
 Insulation – insulating layers of fat,
fur or feathers to prevent heat loss.
 Metabolism – metabolic rate can be
varied to generate more or less heat.
Endotherms also use their skin to vary
their rate of heat loss and maintain a
constant core body temperature.
Too Cold?
Nervous impulses send
messages:
 to the sweat glands which stop any
_______________
 blood vessels _____________ to prevent
the loss of heat through ______________
 Blood circulates _____________and away
from extremities
 breathing rate ______________
 Glands secrete adrenaline and thyroxin to
____________ metabolic rate
 metabolic rate increases (reactions
usually ________________)
 Muscles _______________ – respiration
creates heat and friction
 Muscles contract to make _____________
stand up and trap warm air against the
skin
Vasoconstriction
 This is basically the opposite of ____________________
 When you are cold, the capillaries near the surface of your skin get
_______________(constrict) and some shut off.
 This means _____________comes near the surface of the skin and less heat is
lost.
 This is why your fingers and toes might go ____________ when they are cold!
 is controlled by the sympathetic nervous system
 decreases blood flow to the skin from internal organs, which
 decreases the transfer of heat from the internal body organs to the skin
 allows less heat to be lost from the body surface
 cools the skin
VasodilationVasoconstriction
Cold day Hot day
Frostbite
 The blood vessels in the skin _____________in very cold conditions to preserve
heat.
 If this is prolonged it ____________the cells peripheral tissue of nutrient and
heat. When nerve cells stop working no signals get sent to the brain, the fingers
and toes go numb.
 If this happens for a short time it can be reversed. If it happens for longer the
___________________i.e. frostbite
Metabolism
 The _____________________stimulates the adrenal medulla via sympathetic
nerves
 The ____________ secretes adrenaline and noradrenaline into the blood
 This increases ________________, increasing heat production
 This process helps maintain internal body temperature
Shivering
 Shivering is actually __________________________occurring at a rate of
around ten to twenty per second
 The ______________________ stimulates parts of the brain that increase
skeletal muscle tone
 This increases body _________________________
Piloerection
 When you are cold, small muscles in the skin are activated making
the_____________on your skin stand up.
 The hairs trap a layer of air next to the skin, which is warmed by body heat and
becomes an ______________________preventing air flow to the skin and
slows heat loss
 This is sometimes called ‘_______________or ‘ piloerection’
Skin
Hairs
Trapped air
forms
insulation
hair lies flat on
the skin
the muscle is
hair stands up and a
goose bump appears
the muscle
body temperature
normal
body temperature falls
Behavioural Responses
We change our behavioural responses by:
 __________________
 curling into a ball
 putting on more ____________
 using a heating device
 Eating/drinking ____________________
 Exercising to create heat
 Moving out of cold – __________________
Conserving heat
When the system fails…
 If this is ineffective at heating the body goes into a
________________________
 When core body temperature drops below __________
 Metabolic activity ______________
 _______________
 Shivering, skin looks blue (especially lips)
 Slowing of heart rate, breathing rate, blood pressure decreases
 Confusion, difficulty walking
 Frost bite, chill blains
 _________________
 Shelter, more dry clothing, warm drinks – not alcohol
 Hot water bottle, foil blanket, hot bath
 It is important that the return to normal temperature occurs slowly and
from the core out
 If left untreated ______________ occurs
Basics of Temperature Regulation
Effector Response to low temperature Response to high temperature
Smooth muscles in
peripheral arterioles in
the skin.
Muscles contract causing vasoconstriction. Less
heat is carried from the core to the surface of the
body, maintaining core temperature. Extremities
can turn blue and feel cold and can even be
damaged (frostbite).
Muscles relax causing vasodilation. More heat is
carried from the core to the surface, where it is lost
by convection and radiation. Skin turns red.
Sweat glands No sweat produced. Glands secrete sweat onto surface of skin, where it
evaporates. This is an endothermic process and
water has a high latent heat of evaporation, so it
takes heat from the body.
Erector pili muscles in
skin
(attached to skin hairs)
Muscles contract, raising skin hairs and trapping an
insulating layer of still, warm air next to the skin.
Not very effective in humans, just causing
“goosebumps”.
Muscles relax, lowering the skin hairs and allowing
air to circulate over the skin, encouraging
convection and evaporation.
Skeletal muscles Muscles contract and relax repeatedly, generating
heat by friction and from metabolic reactions.
No shivering.
Adrenal and thyroid
glands
Glands secrete adrenaline and thyroxine
respectively, which increase the metabolic rate in
different tissues, especially the liver, so generating
heat.
Glands stop releasing adrenaline and thyroxine.
Behaviour Curling up, huddling, finding shelter, putting on
more clothes.
Stretching out, finding shade, swimming, removing
clothes.
39 of 12 © Boardworks Ltd 2009
Physiological thermoregulation
6 Steps to Effective Paraphrasing
1. Reread the original passage until you understand its full meaning.
2. Set the original aside, and write your paraphrase on a note card.
3. Jot down a few words below your paraphrase to remind you later how you envision using this material. At the
top of the note card, write a key word or phrase to indicate the subject of your paraphrase.
4. Check your rendition with the original to make sure that your version accurately expresses all the essential
information in a new form.
5. Use quotation marks to identify any unique term or phraseology you have borrowed exactly from the source.
6. Record the source (including the page) on your note card so that you can credit it easily if you decide to
incorporate the material into your paper.
Example of Paraphrasing
The original passage:
Students frequently overuse direct quotation in taking notes, and as a result they overuse quotations in the
final [research] paper. Probably only about 10% of your final manuscript should appear as directly quoted
matter. Therefore, you should strive to limit the amount of exact transcribing of source materials while
taking notes. Lester, James D. Writing Research Papers. 2nd ed. (1976): 46-47.
A legitimate paraphrase:
In research papers students often quote excessively, failing to keep quoted material down to a desirable
level. Since the problem usually originates during note taking, it is essential to minimize the material
recorded verbatim (Lester 46-47).
An acceptable summary:
Students should take just a few notes in direct quotation from sources to help minimize the amount of
quoted material in a research paper (Lester 46-47).
A plagiarized version:
Students often use too many direct quotations when they take notes, resulting in too many of them in the
final research paper. In fact, probably only about 10% of the final copy should consist of directly quoted
material. So it is important to limit the amount of source material copied while taking notes.
Now What?
 Now you have a basic understanding of thermoregulation
 Next you need to go to the moodle and complete the rest of the pre learning
activities, while you do these you need to be filling in the research table in
google docs
 Any questions not completed after completing the moodle prelearning you will
need to go and find the answers to on your own
 Print off the completed google table and bring it to class
 Make a bibliography of your references, print it off along with any diagrams you
want to use and bring them to class
 Use your notes to complete the report write up based on a scenario on
thermoregulation

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Homeostasis 2015 Lesson Notes

  • 3. Homeostasis  ________________- body’s ability to maintain a constant internal environment.  Required for proper functioning of the body because the ______________ that control all metabolic activity essential for life, are very sensitive to changes in their environment.  Thus constant state must be maintained in spite of changing the ____________________________.
  • 4. Balancing Act The following factors need to be kept in balance:  Body temperature  Water (osmotic pressure)  Blood sugar  Carbon dioxide concentration  Oxygen concentration  pH  Mineral salts
  • 5. Negative Feedback  When a condition in the body changes from the norm, a __________is sent to a control center (usually the _____________ in the brain).  The control center then instructs _____________ (_________________) to respond and _____________ the change.  The control center then _________________ a change in temperature as a result of the ________________, it then sends a message to _______________ the response or stop it all together if temperatures have returned to ______________  Works in the ______________ direction to the stimulus hence _________________,  eg you are hot from running, so brain tells your body to sweat to cool you down. Once you are cool your brain tells your body to stop or slow down sweating.
  • 7. Adaptive Advantage  Organisms can _________to the changing environments and therefore occupy ___________________, hence reducing ______________  The more advanced an animal’s ________________ systems, the greater its chance of ______________with a changing environment = survival of organism  If _______________ processes can continue despite a _________________ environment, an organism is able to inhabit a wider range of habitats and _____________ more successfully to maintain its population. = survival of species
  • 8. Why Regulate Heat?  Chemical reactions occurring in cells are very ___________  _____________ that control cellular activity are heat- sensitive  Many _________________can only function properly if they float freely in the lipid bilayer, which is only possible if it is liquid; at low temperature the bilayer ___________.  At around 85ºC, the ________________holding the two strands of __________ together break, causing it to become single stranded.
  • 9. Why Regulate Heat  Enables mammals to successfully live in a wider variety of habitats – reduces ______________________  Always ready for _____________; can be active at a variety of times of day and night  Their __________ capacity is many times that of cold blooded animals  Not greatly affected by __________temperatures.  Muscles provide ___________ power; capable of sustained high activity.
  • 10. How We Lose and Gain Heat  Body temperature is affected by the ____________, amount of _________ (____________________________), BMI, illness, hydration, ______________  Heat can be gained or lost from any place where the body is in ______________ with the environment (skin and lungs)  Heat can be gained or lost by:  Conduction  Convection  Radiation  Evaporation
  • 11. How is Temperature Monitored?  The _______________ in the brain monitors the temperature of the __________ flowing through it  This is called the _____________________as it is sensing temperature at the _______ of the body.  The hypothalamus receives information regarding changes in external temperature from __________________  There are two types of receptors, hot and cold.  ______________relay the messages to and from receptors and the hypothalamus and effector cells
  • 12.
  • 13.
  • 14. Too Hot? Nervous impulses send messages: to the _____________ glands which start to sweat in order to lower the body temperature through evaporation, ______________to lose heat through conduction breathing rate ____________(brings more cooler air into body) ____________lowering skin hairs letting more air flow across skin to lose heat by convection and evaporation - No ___________ Behavioral responses Metabolic rate __________
  • 15.
  • 16. Sweating  When you are hot, ________________are stimulated to release sweat.  Heat energy from your skin is used to turn the liquid sweat into gas - sweat ______________  Because heat is lost, your___________ cools down as does the _________ flowing past  Deep in the dermis are supplied by sympathetic nerve fibres.  In humans most sweat glands are eccrine glands and secrete a dilute salt solution.  Sweat doesn’t work in a humid environment  Environmental temperature > body temp for sweating to be effective
  • 17. Vasodilation  Your blood carries most of the heat energy in your body.  There are small blood vessels called ___________ just underneath your skin.  When you are hot, these capillaries get___________(dilate) so more blood comes close to the surface of the skin and heat is lost.  This is why some people go _________when they are hot!
  • 18. If the temperature rises, the blood vessel dilates (gets bigger). This means more heat is lost from the surface of the skin
  • 19. Metabolic Rate  The ___________________changes through a reduction in the secretion of thyroxine  This results in a ____________ in metabolic rate  The decrease in metabolic rate causes _____________to be produced in the body
  • 20. Behavioural Responses We change our behavioural responses by:  _____________(decreasing activity)  staying in the shade  _______________________  wearing less clothing  ________________  Submerging body in cold water  _____________________  Fanning ourselves Chicks seek shade.
  • 21. When the system fails…  If the body cannot lower its temperature it goes into a _____________ STATE  Resulting in heat exhaustion ______________  Resulting in heat stroke over _____________  Often dehydration also occurs at the same time ________________  Red skin, no sweating, fever, disorientation, pinpoint pupils, shallow breathing _______________  Cooling blood and constricting blood vessels by submersing body in ice water  Stretch body out to increase surface area in contact with cool air  Move into shade  Remove clothing  Give cold fluids  Ice packs/wet towels
  • 22. Fever  This is usually associated with _______________.  The immune system produces fever-inducing chemicals called _____________, which travel through the blood to the hypothalamus, where they trick it into raising the body temperature.  ________________________lower temperature by blocking the production of pyrogens.  Apply cold wet clothes  Remove clothing  Seek medical care to treat infection – antibiotics for bacterial infections If left un treated person can have ___________________________.
  • 24. 24 of 12 © Boardworks Ltd 2009 Thermoregulation in endotherms Endotherms generate most of their heat metabolically. As they are warmer than their environment they tend to lose body heat to their surroundings. Adaptations for heat conservation include:  Insulation – insulating layers of fat, fur or feathers to prevent heat loss.  Metabolism – metabolic rate can be varied to generate more or less heat. Endotherms also use their skin to vary their rate of heat loss and maintain a constant core body temperature.
  • 25. Too Cold? Nervous impulses send messages:  to the sweat glands which stop any _______________  blood vessels _____________ to prevent the loss of heat through ______________  Blood circulates _____________and away from extremities  breathing rate ______________  Glands secrete adrenaline and thyroxin to ____________ metabolic rate  metabolic rate increases (reactions usually ________________)  Muscles _______________ – respiration creates heat and friction  Muscles contract to make _____________ stand up and trap warm air against the skin
  • 26.
  • 27. Vasoconstriction  This is basically the opposite of ____________________  When you are cold, the capillaries near the surface of your skin get _______________(constrict) and some shut off.  This means _____________comes near the surface of the skin and less heat is lost.  This is why your fingers and toes might go ____________ when they are cold!  is controlled by the sympathetic nervous system  decreases blood flow to the skin from internal organs, which  decreases the transfer of heat from the internal body organs to the skin  allows less heat to be lost from the body surface  cools the skin VasodilationVasoconstriction Cold day Hot day
  • 28. Frostbite  The blood vessels in the skin _____________in very cold conditions to preserve heat.  If this is prolonged it ____________the cells peripheral tissue of nutrient and heat. When nerve cells stop working no signals get sent to the brain, the fingers and toes go numb.  If this happens for a short time it can be reversed. If it happens for longer the ___________________i.e. frostbite
  • 29. Metabolism  The _____________________stimulates the adrenal medulla via sympathetic nerves  The ____________ secretes adrenaline and noradrenaline into the blood  This increases ________________, increasing heat production  This process helps maintain internal body temperature Shivering  Shivering is actually __________________________occurring at a rate of around ten to twenty per second  The ______________________ stimulates parts of the brain that increase skeletal muscle tone  This increases body _________________________
  • 30. Piloerection  When you are cold, small muscles in the skin are activated making the_____________on your skin stand up.  The hairs trap a layer of air next to the skin, which is warmed by body heat and becomes an ______________________preventing air flow to the skin and slows heat loss  This is sometimes called ‘_______________or ‘ piloerection’ Skin Hairs Trapped air forms insulation
  • 31. hair lies flat on the skin the muscle is hair stands up and a goose bump appears the muscle body temperature normal body temperature falls
  • 32. Behavioural Responses We change our behavioural responses by:  __________________  curling into a ball  putting on more ____________  using a heating device  Eating/drinking ____________________  Exercising to create heat  Moving out of cold – __________________
  • 34. When the system fails…  If this is ineffective at heating the body goes into a ________________________  When core body temperature drops below __________  Metabolic activity ______________  _______________  Shivering, skin looks blue (especially lips)  Slowing of heart rate, breathing rate, blood pressure decreases  Confusion, difficulty walking  Frost bite, chill blains  _________________  Shelter, more dry clothing, warm drinks – not alcohol  Hot water bottle, foil blanket, hot bath  It is important that the return to normal temperature occurs slowly and from the core out  If left untreated ______________ occurs
  • 35.
  • 36. Basics of Temperature Regulation
  • 37.
  • 38. Effector Response to low temperature Response to high temperature Smooth muscles in peripheral arterioles in the skin. Muscles contract causing vasoconstriction. Less heat is carried from the core to the surface of the body, maintaining core temperature. Extremities can turn blue and feel cold and can even be damaged (frostbite). Muscles relax causing vasodilation. More heat is carried from the core to the surface, where it is lost by convection and radiation. Skin turns red. Sweat glands No sweat produced. Glands secrete sweat onto surface of skin, where it evaporates. This is an endothermic process and water has a high latent heat of evaporation, so it takes heat from the body. Erector pili muscles in skin (attached to skin hairs) Muscles contract, raising skin hairs and trapping an insulating layer of still, warm air next to the skin. Not very effective in humans, just causing “goosebumps”. Muscles relax, lowering the skin hairs and allowing air to circulate over the skin, encouraging convection and evaporation. Skeletal muscles Muscles contract and relax repeatedly, generating heat by friction and from metabolic reactions. No shivering. Adrenal and thyroid glands Glands secrete adrenaline and thyroxine respectively, which increase the metabolic rate in different tissues, especially the liver, so generating heat. Glands stop releasing adrenaline and thyroxine. Behaviour Curling up, huddling, finding shelter, putting on more clothes. Stretching out, finding shade, swimming, removing clothes.
  • 39. 39 of 12 © Boardworks Ltd 2009 Physiological thermoregulation
  • 40. 6 Steps to Effective Paraphrasing 1. Reread the original passage until you understand its full meaning. 2. Set the original aside, and write your paraphrase on a note card. 3. Jot down a few words below your paraphrase to remind you later how you envision using this material. At the top of the note card, write a key word or phrase to indicate the subject of your paraphrase. 4. Check your rendition with the original to make sure that your version accurately expresses all the essential information in a new form. 5. Use quotation marks to identify any unique term or phraseology you have borrowed exactly from the source. 6. Record the source (including the page) on your note card so that you can credit it easily if you decide to incorporate the material into your paper.
  • 41. Example of Paraphrasing The original passage: Students frequently overuse direct quotation in taking notes, and as a result they overuse quotations in the final [research] paper. Probably only about 10% of your final manuscript should appear as directly quoted matter. Therefore, you should strive to limit the amount of exact transcribing of source materials while taking notes. Lester, James D. Writing Research Papers. 2nd ed. (1976): 46-47. A legitimate paraphrase: In research papers students often quote excessively, failing to keep quoted material down to a desirable level. Since the problem usually originates during note taking, it is essential to minimize the material recorded verbatim (Lester 46-47). An acceptable summary: Students should take just a few notes in direct quotation from sources to help minimize the amount of quoted material in a research paper (Lester 46-47). A plagiarized version: Students often use too many direct quotations when they take notes, resulting in too many of them in the final research paper. In fact, probably only about 10% of the final copy should consist of directly quoted material. So it is important to limit the amount of source material copied while taking notes.
  • 42. Now What?  Now you have a basic understanding of thermoregulation  Next you need to go to the moodle and complete the rest of the pre learning activities, while you do these you need to be filling in the research table in google docs  Any questions not completed after completing the moodle prelearning you will need to go and find the answers to on your own  Print off the completed google table and bring it to class  Make a bibliography of your references, print it off along with any diagrams you want to use and bring them to class  Use your notes to complete the report write up based on a scenario on thermoregulation