This document discusses the Hardy-Weinberg law of genetic equilibrium. It states that in a large, randomly mating population, the frequencies of genotypes will remain constant from generation to generation in the absence of evolutionary influences like mutation, migration, genetic drift and non-random mating. The law establishes that the frequency of alleles A and a will be p and q, and the frequencies of genotypes AA, Aa and aa will be p^2, 2pq and q^2 respectively, where p + q = 1. The document provides examples of calculating genotype and gamete frequencies under Hardy-Weinberg equilibrium.
According to Hardy (England,1908) and Weinberg (Germany,1909), gene and genotype frequency of a Mendelian population remain constant generation after generation unless there is selection,mutation,migration or random drift.
It is the fundamental law of population genetics and provides the basis for studying Mendelian populations ( Mendelian population: A group of sexually inbreeding organisms living within a circumscribed area). It describes populations that are not evolving.
This powerpoint gives a clear picture on inbreeding and also about outbreeding of higher organisms. This also explains the advantages and disadvantages of the above said topics. the methods of inbreeding and reasons for inbreeding also given in this powerpoint.
According to Hardy (England,1908) and Weinberg (Germany,1909), gene and genotype frequency of a Mendelian population remain constant generation after generation unless there is selection,mutation,migration or random drift.
It is the fundamental law of population genetics and provides the basis for studying Mendelian populations ( Mendelian population: A group of sexually inbreeding organisms living within a circumscribed area). It describes populations that are not evolving.
This powerpoint gives a clear picture on inbreeding and also about outbreeding of higher organisms. This also explains the advantages and disadvantages of the above said topics. the methods of inbreeding and reasons for inbreeding also given in this powerpoint.
Basics of Undergraduate/university fellows
Complementation between two non-allelic genes (C and P) are essential for production
of a particular or special phenotype i.e., complementary factor.
Two genes involved in a specific pathway and their functional products are required
for gene expression, then one recessive allelic pair at either allelic pair would result in
the mutant phenotype.
When Dominant alleles are present together, they complement each other to yield
complementary factor resulting in a special phenotype.
They are called complementary genes.
When either of gene loci have homozygous recessive alleles (i.e., genotypes of ccPP,
ccPp, CCpp, Ccpp and ccpp), they produce identical phenotypes and change F2 ratio
to 9:7.
Cross- pollinated crops are highly heterozygous due to the free intermating among their plants. They are often referred to as random mating populations because each individual of the population has equal opportunity of mating with any other individual of that population. Such a population is also known as Mendelian population or panmictic population. A population, in this case, consists of all such individuals that share the same gene pool, i.e., have an opportunity to intermate with each other and contribute to the next generation of the population. To understand the genetic make - up of such populations a sophisticated field of study, population genetics, has been developed. The Hardy Weinberg law states that in a large random mating population gene and genotype frequency remain constant generation after generation unless there is selection, mutation, migration or random drift. This is the fundamental law of population genetics and provides the basis for studying Mendelian populations. The law is proposed independently by G. H. Hardy (a mathematician) and W. Weinberg (a physician).
This power point presentation is designed to explain deviation of Mendelian dihybrid ratio due to interaction of genes which may be of following types
1.Two gene pairs affecting same character – 9:3:3:1
2.Epistasis, one gene hides effect of other
a) Recessive Epistasis - 9:3:4
b) Dominant epistasis - 12:3:1
3.Complementary genes - 9:7 ( 2 genes responsible for production of a particular phenotype )
4. Duplicate genes – 15:1 ( same effect given by either of two genes )
5. Polymeric gene action - 9:6:1
6. Inhibitory gene action - 13 : 3
Each interaction is typical in itself and ratios obtained are different
Basics of Undergraduate/university fellows
Complementation between two non-allelic genes (C and P) are essential for production
of a particular or special phenotype i.e., complementary factor.
Two genes involved in a specific pathway and their functional products are required
for gene expression, then one recessive allelic pair at either allelic pair would result in
the mutant phenotype.
When Dominant alleles are present together, they complement each other to yield
complementary factor resulting in a special phenotype.
They are called complementary genes.
When either of gene loci have homozygous recessive alleles (i.e., genotypes of ccPP,
ccPp, CCpp, Ccpp and ccpp), they produce identical phenotypes and change F2 ratio
to 9:7.
Cross- pollinated crops are highly heterozygous due to the free intermating among their plants. They are often referred to as random mating populations because each individual of the population has equal opportunity of mating with any other individual of that population. Such a population is also known as Mendelian population or panmictic population. A population, in this case, consists of all such individuals that share the same gene pool, i.e., have an opportunity to intermate with each other and contribute to the next generation of the population. To understand the genetic make - up of such populations a sophisticated field of study, population genetics, has been developed. The Hardy Weinberg law states that in a large random mating population gene and genotype frequency remain constant generation after generation unless there is selection, mutation, migration or random drift. This is the fundamental law of population genetics and provides the basis for studying Mendelian populations. The law is proposed independently by G. H. Hardy (a mathematician) and W. Weinberg (a physician).
This power point presentation is designed to explain deviation of Mendelian dihybrid ratio due to interaction of genes which may be of following types
1.Two gene pairs affecting same character – 9:3:3:1
2.Epistasis, one gene hides effect of other
a) Recessive Epistasis - 9:3:4
b) Dominant epistasis - 12:3:1
3.Complementary genes - 9:7 ( 2 genes responsible for production of a particular phenotype )
4. Duplicate genes – 15:1 ( same effect given by either of two genes )
5. Polymeric gene action - 9:6:1
6. Inhibitory gene action - 13 : 3
Each interaction is typical in itself and ratios obtained are different
Population Genetics & Hardy - Weinberg Principle.pdfSuraj Singh
This presentation is all about the population genetics.
In this presentation I would like to explain about the population genetics, calculation of allele frequencies, calculation of frequencies of sex - linked alleles.
Also there is a detailed explanation of Hardey-Weinberg equilibrium or principle.
In the last there are few key points regarding with the assumptions and steps for the Hardy-Weinberg principle.
Hardy Weinberg law
Hardy Weinberg Equilibrium with Solved Questions|CSIR NET|Life Sciences|GATE|JRF|ICMR|
Video link: https://youtu.be/CUKGoxpptM8
Hardy Weinberg Law along with the assumptions the law is based on. Calculation of allelic and genotypic frequencies. Application of Hardy Weinberg law to different cases viz Multiple alleles, Polyploidy, Inbreeding and X-linked + Questions are discussed.
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The presentation contains the description about various parts of morphology of the honey bee viz: head, type of mouthpart, abdomen including the legs and wings, and the abdomen.
Safalta Digital marketing institute in Noida, provide complete applications that encompass a huge range of virtual advertising and marketing additives, which includes search engine optimization, virtual communication advertising, pay-per-click on marketing, content material advertising, internet analytics, and greater. These university courses are designed for students who possess a comprehensive understanding of virtual marketing strategies and attributes.Safalta Digital Marketing Institute in Noida is a first choice for young individuals or students who are looking to start their careers in the field of digital advertising. The institute gives specialized courses designed and certification.
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Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
Model Attribute Check Company Auto PropertyCeline George
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It is possible to hide or invisible some fields in odoo. Commonly using “invisible” attribute in the field definition to invisible the fields. This slide will show how to make a field invisible in odoo 17.
Macroeconomics- Movie Location
This will be used as part of your Personal Professional Portfolio once graded.
Objective:
Prepare a presentation or a paper using research, basic comparative analysis, data organization and application of economic information. You will make an informed assessment of an economic climate outside of the United States to accomplish an entertainment industry objective.
A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
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Hardy weinberg law
1. Plant Breeding: Theory and Practice: V.L. Chopra (2012)
Breeding Field Crops: David Allen Sleper and John Milton Poehlman
Plant Breeding: Principles and Methods- B.D.Singh
Principles and Practice of Plant Breeding- J.R. Sharma
Principles of Plant Breeding: R.W. Allard
Plant Breeding: N.W. Simmonds
Reference Books
3. Random Mating PopulationsRandom Mating Populations
Each individual of the population has equal opportunityEach individual of the population has equal opportunity
of mating with any other individual of that population such aof mating with any other individual of that population such a
population is called random mating populations, Mendelianpopulation is called random mating populations, Mendelian
populations or panmictic populations.populations or panmictic populations.
Gene PoolGene Pool
Gene pool may be defined as the sum total of all theGene pool may be defined as the sum total of all the
genes present in the populationgenes present in the population
PopulationPopulation
It consists of all such individuals that share the same gene pool, i.e., have an opportunity toIt consists of all such individuals that share the same gene pool, i.e., have an opportunity to
intermate with each other and contribute to next generation of the populationintermate with each other and contribute to next generation of the population
4. Population GeneticsPopulation Genetics
Population genetics is that branch of geneticsPopulation genetics is that branch of genetics
that is concerned with the evolutionary processes ofthat is concerned with the evolutionary processes of
natural selection, genetic drift, mutation, migration,natural selection, genetic drift, mutation, migration,
and random mating.and random mating.
Hardy-Weinberg LawHardy-Weinberg Law
• This law was independently developed by Hardy, inThis law was independently developed by Hardy, in
1908, in England and Weinberg, in 1909, in Germany1908, in England and Weinberg, in 1909, in Germany
• ““Gene and genotype frequency in a MendilianGene and genotype frequency in a Mendilian
population remain constant generation after generationpopulation remain constant generation after generation
if there is no selection, mutation, migration or randomif there is no selection, mutation, migration or random
drift”drift”
5. Frequencies of three genotypes for a locus with twoFrequencies of three genotypes for a locus with two
alleles, A and aalleles, A and a
AAAA p2p2
AaAa 2pq2pq
aaaa q2q2
Where, p represents the frequency of A and q of a allele inWhere, p represents the frequency of A and q of a allele in
the population and p+q=1the population and p+q=1
Such a population is said to be at equilibrium since theSuch a population is said to be at equilibrium since the
genotype frequencies would be stable. This equilibrium isgenotype frequencies would be stable. This equilibrium is
known as Hardy-Weinberg equilibrium. A population isknown as Hardy-Weinberg equilibrium. A population is
said to be at equilibrium when the frequencies of the threesaid to be at equilibrium when the frequencies of the three
genotypes, AA, Aa and aa are p2, 2pq and q2.genotypes, AA, Aa and aa are p2, 2pq and q2.
6. Single gene with two allele, A and a there would be three genotypes,Single gene with two allele, A and a there would be three genotypes,
AA, Aa and aaAA, Aa and aa
Suppose the population has N individualsSuppose the population has N individuals
D individuals are AAD individuals are AA
H individuals are AaH individuals are Aa
R individuals are aaR individuals are aa
Hence,Hence,
D+H+R=ND+H+R=N
Total no. of alleles at this locus in the population would be 2N, sinceTotal no. of alleles at this locus in the population would be 2N, since
each individual has two alleles at single locuseach individual has two alleles at single locus
Total no. of A alleles = 2D+H, the ratio (2D+H)/2NTotal no. of A alleles = 2D+H, the ratio (2D+H)/2N
therefore,therefore,
p= (2D+H)/2N or (D+½H)/Np= (2D+H)/2N or (D+½H)/N
q= (2R+H)/2N or (R+½H)/Nq= (2R+H)/2N or (R+½H)/N
since,since, p+q=1p+q=1
Therefore p=1-q or q=1-pTherefore p=1-q or q=1-p
7. Frequencies of different genotypes producedFrequencies of different genotypes produced
by random union between A and aby random union between A and a
p Ap A q aq a
p Ap A p2 AAp2 AA pq Aapq Aa
q aq a pq Aapq Aa q2 aaq2 aa
♂♂♀♀
Therefore, genotype frequencies in the next generation would be p2 2pq q2
8. It may be noted that D=p2, H=2pq and R=q2, Further, N=1It may be noted that D=p2, H=2pq and R=q2, Further, N=1
since,since,
p2+2pq+q2=(p+q)2p2+2pq+q2=(p+q)2
andand p+q=1p+q=1
Hence, p2+2pq+q2=1Hence, p2+2pq+q2=1
GenotypeGenotype AAAA AaAa aaaa
FrequencyFrequency p2p2 2pq2pq q2q2
This population would produce two types of gametes A and a; their
frequencies can be calculated in a similar manner as described before.
9. The frequencies of A and a gametes produced by theThe frequencies of A and a gametes produced by the
population may be calculated as follows;population may be calculated as follows;
Frequencies of gametes containing A allele= (D+½H)/NFrequencies of gametes containing A allele= (D+½H)/N
= (p2+pq)/1=p2+pq= (p2+pq)/1=p2+pq
= p(p+q)=p (since p+q=1)= p(p+q)=p (since p+q=1)
Frequencies of gametes containing a allele = (R+½H)/NFrequencies of gametes containing a allele = (R+½H)/N
= (q2+pq)/1=q2+pq= (q2+pq)/1=q2+pq
= q(p+q)=q (since p+q=1)= q(p+q)=q (since p+q=1)
10. Consequences of random mating of genotypes in aConsequences of random mating of genotypes in a
Mendelian populationMendelian population
MatingMating Freq. of MatingFreq. of Mating Freq. of progeny from theFreq. of progeny from the
matingmating
AAAA AaAa AaAa
AA x AAAA x AA p2 x p2=p4p2 x p2=p4 p4p4
AA x AaAA x Aa 2(p2x2pq)=4p3q2(p2x2pq)=4p3q 2p3q2p3q 2p3q2p3q
AA x aaAA x aa 2(p2 x q2)=2p2q22(p2 x q2)=2p2q2 2p2q22p2q2
Aa x AaAa x Aa (2pq x 2pq)=4p2q2(2pq x 2pq)=4p2q2 p2q2p2q2 2p2q22p2q2 P2q2P2q2
Aa x aaAa x aa 2(2pq x q2)=4pq32(2pq x q2)=4pq3 2pq32pq3 2pq32pq3
aa x aaaa x aa q2 x q2=q4q2 x q2=q4 q4q4
11. The frequency of progeny with AA genotype would be,The frequency of progeny with AA genotype would be,
=p4+2p3q+p2q2=p4+2p3q+p2q2
=p2(p2+2pq+q2) (p2 is taken as common)=p2(p2+2pq+q2) (p2 is taken as common)
=p2=p2 ( since p2+2pq+q2=1)( since p2+2pq+q2=1)
Similarly, the frequency of aa progeny would be,Similarly, the frequency of aa progeny would be,
=p2q2+2pq3+q4=p2q2+2pq3+q4
=q2(p2+2pq+q2) (q2 is taken as common)=q2(p2+2pq+q2) (q2 is taken as common)
=q2=q2 (since p2+2pq+q2=1)(since p2+2pq+q2=1)
And the frequency of Aa progeny would be,And the frequency of Aa progeny would be,
=2p3q+2p2q2+2p2q2+2pq3=2p3q+2p2q2+2p2q2+2pq3
=2p3q+4p2q2+2pq3=2p3q+4p2q2+2pq3
=2pq (p2+2pq+q2) (2pq is taken as common)=2pq (p2+2pq+q2) (2pq is taken as common)
=2pq=2pq (since p2+2pq+q2=1)(since p2+2pq+q2=1)