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Presented By…
Maitri. M. Thakor
M.Sc. (Botany)
Department of life sciences,
H.N.G.U., Patan.
1
 Introduction
 Difference between qualitative &
quantitative traits
 The multiple factor Hypothesis
 Some characters of quantitative traits
☻Kernel colour in Wheat
☻Skin colour in human
☻Eye colour in human
2
 Quantitative genetics have possibility of
continuous variations.
 In 1760, Joseph Kolreuter reported first
case of continuous variation due to
quantitative trait.
 Quantitative Characters are an inherited
character that expressed phenotypically in
all degrees of variation between one often
indefinite extreme and another : a
character determined by polygenes.
3
Qualitative Trait Quantitative Traits
1)Characters of kind.
2)Discontinuous variation;
distinct phenotypic
classes.
3)Single gene effect.
4)Concerned with individual
matings & their progeny.
5)Analysed by making counts
and ratios.
1)Characters of degree.
2)Continuous variations;
phenotypic measure-
ments from a spectrum.
3)Polygenic control; effects
of single genes too slight
to be detected.
4)Concerned with population
of organisms consisting of
all possible kinds of
matings.
5) Statistical analyses.
4
Qualitative Trait Quantitative Trait
(6) Ex.;
 Form (round/wrinkled
seeds of pea),
Structure ( horned /hornless
conditions in cattle’s)
Pigments (black/white coat
of guinea pigs)
Antigens & Antibodies
etc.
(6) Ex.;
In human ( Skin colour, Eye
colour, Hair colour, Weight,
Height etc.)
In plants (Seed colour in
Wheat, Ear size in Maize,
Corolla length in tobacco
etc.)
In animals (Size in chicken,
Size in Rabbit, White spotting
in mice etc.)
etc.
5
 A gene, individually producing a slight
effect on the phenotype but in
combination with a few(2) or many other
genes, controls as quantitative character
is called as a Polygene.
 Since there are many genes of this kind
for one quantitative character, they are
also known as multiple factors, each
factor having too small an effect to be
traced.
6
 Those genes(alleles) which contribute to
the trait involved are called Contributing ,
effective or active genes(alleles).
 Those genes(alleles) which do not
contribute to the trait involved are called
non- contributing, non-effective or null
genes(alleles).
7
 The inheritance of relatively simpler
quantitative traits due to multiple factors
of polygenes will be illustrated in this
section with the help of three examples:
(1) Kernel colour in Wheat
(Studied by – H. Nilsson - Ehle )
(2) Skin colour in humans
(Studied by – C. B. Devenport )
(3) Eye colour in human
(Studied by – Burns & Battino-1989 )
8
 A whole grain or seed of a cereal plant
such as corn, wheat, barley, etc.. Is called
Kernel.
 Kernel colour in wheat was studied by
Swedish geneticist H. Nilsson – Ehle for the
first time in 1908.
P : Red kernel White kernel
R1R1R2R2 (Dominant) r1r1r2r2 ( Recessive)
R1R2 r1r2
F1: R1r1R2r2 ( Light Red )
9
 F2 Generation :
10
Genotype Genotypic
ratio
Number of
Contributing
alleles
Phenotype Phenotypic
ratio
R1R1R2R2 1 4 Red 1
R1R1R2r2 2 3 Medium red
R1r1R2R2 2 3 Medium red
R1r1R2r2 4 2 Light red
R1R1r2r2 1 2 Light red
r1r1R2R2 1 2 Light red
R1r1r2r2 2 1 Very light
red
r1r1R2r2 2 1 Very light
red
r1r1r2r2 1 0 White 1
11
 This character was given by Davenport
(1913) in Jamaica.
 He found that two pairs of genes, A-a and B-
b cause the differences in skin pigmenta-
tion between negro and Caucasian people.
12
P1: Negro White
AABB aabb
AB ab
F1: AaBb
Mulattoes-
( intermediate skin colour )
F2 generation :
AB Ab aB ab
AB AABB AABb AaBB AaBb
Ab AABb Aabb AaBb Aabb
aB AaBB AaBb aaBB aaBb
ab AaBb Aabb aaBb aabb
13
Phenotype Genotype Genotypic
Frequency
Ratio
Negro(Black) AABB 1 1
Dark AaBB 2
Mulatto AABb 2
Mulatto AaBb 4
Mulatto aaBB 1
Mulatto Aabb 1
Light Aabb 2
Light aaBb 2
White aabb 1 1
14
1 : 4 : 6 : 4 : 1
15
 In human beings, the colour of eye is
found to be determined by Polygenes.
 This genes have been suggested to be X-
linked (see Burns and Battino, 1989).
 At least 9 classes of eye colour can be
recognized in humans.
 In order of increasing amount of melanin
pigmentation, these eye colours can be
designated as light blue, medium blue,
dark blue, grey, green, light brown,
medium brown and dark brown.
16
 Number of contributing alleles for each type
of eye colour of human beings :
Number of
contributing alleles
Eye colour
0 Light blue
1 Medium blue
2 Dark blue
3 Grey
4 Green
5 Hazel
6 Light brown
7 Medium brown
8 Dark brown
17
Different eye colours found in human beings.
18
1) Cell Biology, Genetics, Molecular Biology,
Evolution and Ecology.
Edition : 2008
Author : P. S. Varma,
V.K. Agarwal.
2) Genetics
Edition : 2011 (Fourth)
Author : P. K. Gupta.
3) Genetics
Editon : 2003 (First)
Author : H.V. Bhaskar;
Suresh Kumar.
4) WWW.Slideshare.net
19
20

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Quantitative characters and Genes

  • 1. Presented By… Maitri. M. Thakor M.Sc. (Botany) Department of life sciences, H.N.G.U., Patan. 1
  • 2.  Introduction  Difference between qualitative & quantitative traits  The multiple factor Hypothesis  Some characters of quantitative traits ☻Kernel colour in Wheat ☻Skin colour in human ☻Eye colour in human 2
  • 3.  Quantitative genetics have possibility of continuous variations.  In 1760, Joseph Kolreuter reported first case of continuous variation due to quantitative trait.  Quantitative Characters are an inherited character that expressed phenotypically in all degrees of variation between one often indefinite extreme and another : a character determined by polygenes. 3
  • 4. Qualitative Trait Quantitative Traits 1)Characters of kind. 2)Discontinuous variation; distinct phenotypic classes. 3)Single gene effect. 4)Concerned with individual matings & their progeny. 5)Analysed by making counts and ratios. 1)Characters of degree. 2)Continuous variations; phenotypic measure- ments from a spectrum. 3)Polygenic control; effects of single genes too slight to be detected. 4)Concerned with population of organisms consisting of all possible kinds of matings. 5) Statistical analyses. 4
  • 5. Qualitative Trait Quantitative Trait (6) Ex.;  Form (round/wrinkled seeds of pea), Structure ( horned /hornless conditions in cattle’s) Pigments (black/white coat of guinea pigs) Antigens & Antibodies etc. (6) Ex.; In human ( Skin colour, Eye colour, Hair colour, Weight, Height etc.) In plants (Seed colour in Wheat, Ear size in Maize, Corolla length in tobacco etc.) In animals (Size in chicken, Size in Rabbit, White spotting in mice etc.) etc. 5
  • 6.  A gene, individually producing a slight effect on the phenotype but in combination with a few(2) or many other genes, controls as quantitative character is called as a Polygene.  Since there are many genes of this kind for one quantitative character, they are also known as multiple factors, each factor having too small an effect to be traced. 6
  • 7.  Those genes(alleles) which contribute to the trait involved are called Contributing , effective or active genes(alleles).  Those genes(alleles) which do not contribute to the trait involved are called non- contributing, non-effective or null genes(alleles). 7
  • 8.  The inheritance of relatively simpler quantitative traits due to multiple factors of polygenes will be illustrated in this section with the help of three examples: (1) Kernel colour in Wheat (Studied by – H. Nilsson - Ehle ) (2) Skin colour in humans (Studied by – C. B. Devenport ) (3) Eye colour in human (Studied by – Burns & Battino-1989 ) 8
  • 9.  A whole grain or seed of a cereal plant such as corn, wheat, barley, etc.. Is called Kernel.  Kernel colour in wheat was studied by Swedish geneticist H. Nilsson – Ehle for the first time in 1908. P : Red kernel White kernel R1R1R2R2 (Dominant) r1r1r2r2 ( Recessive) R1R2 r1r2 F1: R1r1R2r2 ( Light Red ) 9
  • 11. Genotype Genotypic ratio Number of Contributing alleles Phenotype Phenotypic ratio R1R1R2R2 1 4 Red 1 R1R1R2r2 2 3 Medium red R1r1R2R2 2 3 Medium red R1r1R2r2 4 2 Light red R1R1r2r2 1 2 Light red r1r1R2R2 1 2 Light red R1r1r2r2 2 1 Very light red r1r1R2r2 2 1 Very light red r1r1r2r2 1 0 White 1 11
  • 12.  This character was given by Davenport (1913) in Jamaica.  He found that two pairs of genes, A-a and B- b cause the differences in skin pigmenta- tion between negro and Caucasian people. 12
  • 13. P1: Negro White AABB aabb AB ab F1: AaBb Mulattoes- ( intermediate skin colour ) F2 generation : AB Ab aB ab AB AABB AABb AaBB AaBb Ab AABb Aabb AaBb Aabb aB AaBB AaBb aaBB aaBb ab AaBb Aabb aaBb aabb 13
  • 14. Phenotype Genotype Genotypic Frequency Ratio Negro(Black) AABB 1 1 Dark AaBB 2 Mulatto AABb 2 Mulatto AaBb 4 Mulatto aaBB 1 Mulatto Aabb 1 Light Aabb 2 Light aaBb 2 White aabb 1 1 14
  • 15. 1 : 4 : 6 : 4 : 1 15
  • 16.  In human beings, the colour of eye is found to be determined by Polygenes.  This genes have been suggested to be X- linked (see Burns and Battino, 1989).  At least 9 classes of eye colour can be recognized in humans.  In order of increasing amount of melanin pigmentation, these eye colours can be designated as light blue, medium blue, dark blue, grey, green, light brown, medium brown and dark brown. 16
  • 17.  Number of contributing alleles for each type of eye colour of human beings : Number of contributing alleles Eye colour 0 Light blue 1 Medium blue 2 Dark blue 3 Grey 4 Green 5 Hazel 6 Light brown 7 Medium brown 8 Dark brown 17
  • 18. Different eye colours found in human beings. 18
  • 19. 1) Cell Biology, Genetics, Molecular Biology, Evolution and Ecology. Edition : 2008 Author : P. S. Varma, V.K. Agarwal. 2) Genetics Edition : 2011 (Fourth) Author : P. K. Gupta. 3) Genetics Editon : 2003 (First) Author : H.V. Bhaskar; Suresh Kumar. 4) WWW.Slideshare.net 19
  • 20. 20