This document discusses footloose industries and factors that attract them to locate along the M4 motorway corridor in the UK. Footloose industries have sophisticated, high-value, low-weight products and can choose their location freely. The M4 corridor is attractive due to its transport links by road and rail, proximity to London and its large market as well as Heathrow Airport, availability of skilled labor from universities, and attractive living environment. Specific industries such as biotechnology, computing, and research centers have located along the corridor, with one example being the Aztec West Business Park near Bristol which provides amenities and access to markets, suppliers, and talent.