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B 3.4 PROBLEM SOLVING SESSIONS (PEDIATRICS)
My child does not
thriveMaryam AL-Qahtani
Learning objective:
What are causes of failure to thrive? Explain
the pathogenesis of any two common
etiological causes
Failure to thrive (FTT) is a term used to describe inadequate growth
or the inability to maintain growth, usually in early childhood.
By definition, include 2%, 5% or 10% of all babies, whether there
was a problem or not.
Introduction
• Growth failure is due to an acute or
chronic disorder that interferes with
nutrient intake, absorption, metabolism, or
excretion or that increases energy
requirements.
Organic
FFT
• Up to 80% of children with growth failure
do not have an apparent organic disorder;
growth failure occurs because of
environmental neglect (e.g. lack of food),
stimulus deprivation, or both.
Non-
organic FFT
What are causes of failure
to thrive?
Causes of organic Failure to thrive
Mechanism Disorder
Decreased nutrient
intake
Cleft lip or palate , CNS disorder (eg, cerebral
palsy)
Gastroesophageal reflux disease
Pyloric stenosis
Malabsorption Celiac disease & Cystic fibrosis
Inflammatory bowel disease
Impaired
metabolism
Chromosomal abnormality (eg, Down syndrome,
Turner syndrome)
Fructose intolerance , galactosemia
Increased excretion Diabetes mellitus , Proteinuria
Increased energy
requirements
Bronchopulmonary dysplasia , Cystic fibrosis
Heart failure , Hyperthyroidism , Infection
Pathophysiology Of
Organic Disease
Celiac disease
Pathophysiology Of
Organic Disease
Celiac disease
Pyloric Stenosis
References
Conclusion:
Thank you

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Failure to thrive (FTT)

  • 1. B 3.4 PROBLEM SOLVING SESSIONS (PEDIATRICS) My child does not thriveMaryam AL-Qahtani
  • 2. Learning objective: What are causes of failure to thrive? Explain the pathogenesis of any two common etiological causes
  • 3. Failure to thrive (FTT) is a term used to describe inadequate growth or the inability to maintain growth, usually in early childhood. By definition, include 2%, 5% or 10% of all babies, whether there was a problem or not. Introduction
  • 4. • Growth failure is due to an acute or chronic disorder that interferes with nutrient intake, absorption, metabolism, or excretion or that increases energy requirements. Organic FFT • Up to 80% of children with growth failure do not have an apparent organic disorder; growth failure occurs because of environmental neglect (e.g. lack of food), stimulus deprivation, or both. Non- organic FFT What are causes of failure to thrive?
  • 5. Causes of organic Failure to thrive Mechanism Disorder Decreased nutrient intake Cleft lip or palate , CNS disorder (eg, cerebral palsy) Gastroesophageal reflux disease Pyloric stenosis Malabsorption Celiac disease & Cystic fibrosis Inflammatory bowel disease Impaired metabolism Chromosomal abnormality (eg, Down syndrome, Turner syndrome) Fructose intolerance , galactosemia Increased excretion Diabetes mellitus , Proteinuria Increased energy requirements Bronchopulmonary dysplasia , Cystic fibrosis Heart failure , Hyperthyroidism , Infection

Editor's Notes

  1. Normally, the body's immune system is designed to protect it from foreign invaders. When people with celiac disease eat foods containing gluten, their immune system forms antibodies to gluten which then attack the intestinal lining. This causes inflammation in the intestines and damages the villi, the hair-like structures on the lining of the small intestine. Nutrients from food are normally absorbed by the villi. If the villi are damaged, the person cannot absorb nutrients properly and ends up malnourished, no matter how much he or she eats
  2. Marked hypertrophy and hyperplasia of the 2 (circular and longitudinal) muscular layers of the pylorus occurs, leading to narrowing of the gastric antrum. The pyloric canal becomes lengthened, and the whole pylorus becomes thickened. The mucosa is usually edematous and thickened. In advanced cases, the stomach becomes markedly dilated in response to near-complete obstruction.