This document discusses organic solvent-water partitioning, specifically: 1. It defines liquid-liquid partitioning as the equilibrium concentration of a solute between an organic solvent phase and water phase (Kilw= Cil/Ciw). 2. It explains that solute-solvent properties like molecular size, polarity, and inter- and intra-molecular interactions influence partitioning between phases. 3. It describes using the octanol-water partition constant (Kow) to measure and relate a compound's hydrophobicity, and methods for finding partition coefficients experimentally or through prediction models.