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DVT & VARICOSE VEINS
Dr. Shair Muhammad Hazara
PhD Public Health (Fellow), MSPH, MSBE, BSN
Deep Vein Thrombosis (DVT)
It is the most common venous disorders
result from incompetent valves in the veins and
obstruction of venous return to the heart, usually
as a result of thrombus.
ETIOLOGY
 Venous stasis
 Vessel wall injury
 Hypercoagulability
RISK FACTORS
• Older age
• Major surgery and orthopedic surgery
• Cancers
• Immobilization
• Pregnancy and the postpartum period
Cont…
• Trauma and minor leg injury
• Previous VTE
• Oral contraceptives
• Hormonal replacement therapy Central venous
catheters
• Obesity
• Infection
PATTERNS OF DEEP VEIN
THROMBOSIS
Popliteal thrombosis
Femoral thrombosis
Iliac thrombosis
Clot formation
Clot can enlarged and extend
Venous valves are damaged(Inflammatory
response)
Postphlebitic syndrome
Cont…
Muscle spasm and changes in intravascular
pressure
Developing thrombus to dislodge & moves
towards heart and lungs
Obstruct perfusion to the lung segments
Cont…
Pulmonary arteries partially or totally obstructed
by embolus
Circulation of the lung segment affected
Lung may undergo severe infarction with massive
tissue destruction
Clinical manifestations
Calf thrombosis
• Calf tenderness
• Distal swelling
Femoral thrombosis
• Tenderness & pain in distal thigh & popliteal
regions
• Swelling
• Calf vein thrombosis
Cont…
Iliofemoral thrombosis
• Massive swelling
• Tenderness & pain in entire extremity
Upper extremity thrombosis
• Swelling of affected extremity
• Dilated superficial veins
• Tenderness & pain
• Impaired mobility
Cont…
• Local warmth
• Mild fever
• Possible venous cord in
the popliteal area
DIAGNOSTIC EVALUATION
History collection
Physical examination
Color flow duplex ultrasound imaging
D- Dimer test
Cont….
Venography
CT venography
MR venography
Treatment
Goals
 To prevent propagation of the clot
 Prevent the development of new thrombi
 Prevent pulmonary emboli
 Limit venous valvular damage
Cont…
 Bed rest
 Leg elevation
 Compression stockings
 Pharmacological measures
Cont…
Unfractionated heparin
• Initial-5000U OR 80U/kg - IV
• Followed by maintain the APTT between 1.5 &
2.5 times the control.
• It given as 5 to 7 days
Cont….
LMWH
Dosage – 250U/ kg every 12 hours.
Eg; enoxaparin, dalteparin.
Warfarin
Dose of 5 mg per day
Cont…
Thrombolytic therapy
Eg;streptokinase, urokinase, recombinant tissue
plasminogen(reteplase, alteplase)
Surgical management
Thrombectomy- transvenous filtration device
• Greenfield filter
• Bird’s nest filter
Guidelines for safe practice
Green field filter
Bird’s nest filter
Varicose veins
These are swollen,twisted and
sometimes painful veins that have filled with
an abnormal collection of blood.
Causes
• Hereditary
• Thrombophelebitis
• Prolonged standing
• Obesity & distended belly
• Pregnancy
Cont…
• Straining-chronic constipation, urinary
retention, chronic cough.
• Prior surgery
• age
Pathophysiology
Generally blood flow from the superficial veins to
the deep veins
To the large veins to the heart
Venous blood flow work against gravity
This is assisted by unidirectional intraluminal
valves in the veins
Cont…
Activity causes intermittent compression of the
veins by muscles
Pressure increases in the vein valves
Incompetent valves
Valve failure
Cont….
Veins become swollon and enlarged
Become hard & tortuous
Feeling of heaviness & pressure
Clinical manifestations
• Aching ,heavy legs
• Appearance of spider veins
• Ankle swelling
• Brownish blue shiny skin discolouration
• Redness, dryness, itching of the affected area
Cont…
• Cramps while standing
• Bleeding during minor injuries
• Hard swollon area
• Whitened irregular scar like patches in the
ankles.
Diagnostic evaluation
History collection
Physical examination
Tourniquet test
Doppler ultrasound
MRI
TREATMENT
Conservative
Elevation of legs
Regular exercises
Compression stockings
Anti inflammatory medications
Cont….
Active
Stripping - Removal of all or part of the
saphenous vein .
Endovascular laser surgery – uses a laser to
destroy the veins.
Radiofrequency ablation – heat to destroy the
affected veins.
Cont…
Ligation – it is usually involved in an incision at
the groin .here they tied saphenous vein to the
femoral vein just at the entrance of the
incision.
Laser therapy
Ablation therapy
Non surgical
Sclerotherapy - Injecting the chemical inside the
vein .
Sclerosant agent-polidocanal, sclerodex.
Lasers – it is used in case of small veins with
vacosity.
Sclerotherapy
Complications
 Varicose ulsers
 Severe bleeding
 Acute necrosis
DVT and Vericose Vein and it causes and treatment

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