1. Identify the difference between vertigo, disequilibrium,, near-syncope, and Undifferentiated dizziness.
2. Identify helpful tests to distinguish peripheral from central vertigo.
3. Understand how to treat different kinds of vertigo
Vertigo is a subtype of dizziness in which a patient inappropriately experiences the perception of motion (usually a spinning motion) due to dysfunction of the vestibular system.
Vertigo is a subtype of dizziness in which a patient inappropriately experiences the perception of motion (usually a spinning motion) due to dysfunction of the vestibular system.
Vertigo is a problem commonly encountered in daily clinical practice.So an uniform approach to a patient with Vertigo is essential to identify the underlying aetiology of Vertigo.
HOW TO MANAGE PATIENTS WITH VERTIGO?
Andradi S.
Department of Neurology. University of Indonesia, Jakarta
disampaikan dalam Simposium PIT IDI Kota Bogor
Vertigo is a problem commonly encountered in daily clinical practice.So an uniform approach to a patient with Vertigo is essential to identify the underlying aetiology of Vertigo.
HOW TO MANAGE PATIENTS WITH VERTIGO?
Andradi S.
Department of Neurology. University of Indonesia, Jakarta
disampaikan dalam Simposium PIT IDI Kota Bogor
Feeling off balance or dizzy after getting off of a ride at the local fair may be normal but if you are experiencing these symptoms in everyday life it may signal a problem with your inner ear, or vestibular system, and you may benefit from vestibular physical therapy.
Hair diseases are disorders primarily associated with the follicles of the hair. Many hair diseases can be associated with distinct underlying disorders. Hair disease may refer to excessive shedding or baldness (or both). Balding can be localized or diffuse, scarring or non-scarring.
Communication is the act of conveying meanings from one entity or group to another through the use of mutually understood signs and semiotic rules
The ability to communicate effectively is an essential skill in today's world. Communication is a dynamic process.
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Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
1. BY: Dr. Hassan Yousef
Consultant Family Medicine, PHCC.
Instructor of Family Medicine in Clinical Medicine, WCMC-Q
Core Faculty Member Family Medicine Training Program , Qatar
Dizziness in primary Care
2. Disclosure of Conflict of Interest
I Dr. Hassan Yousef
DO NOT have a financial
interest/arrangement or affiliation with
anyone in relation to this
program/presentation/organization that
could be perceived as a real or apparent
conflict of interest in the context of the
subject of this presentation.
3. 1. Identify the difference between vertigo, disequilibrium,, near-
syncope, and Undifferentiated dizziness.
2. Identify helpful tests to distinguish peripheral from central
vertigo.
3. Understand how to treat different kinds of vertigo.
Learning Objectives
4. You have 35 years old patient with history strongly suggest
BPPV and Negative Dix-Hallpike test, what is your best
next action?
A. Exclude BPPV.
B. Start betahistadine & follow up
C. Do supine head roll test.
D. Referral for Urgent C.T.
E. Do HINTS Examination
Warm up
5. What does a positive head impulse test imply?
A. The patient has BPPV
B. The patient has vertigo from a vestibular nerve process
C. The patient has a stroke
D. The patient has a brain tumor
E. The patient is intoxicated
Warm up
7. What is your first question for any patient
complaining of dizziness
8. What do you mean by dizziness?
Off- Balance
Spinny
Fainty
Crazy
Disequilibrium Near syncope Lightheaded
ness
Undifferentiated
Vertigo Psychiatric
9. Helping tips
Disequilibrium UndifferentiatedNear syncope
Vertigo
- Neurological
- With walking
- With
standing
e.g. Postural
hypotension
- Medical causes
e.g. Anemia,
hyperthyroidism
,hypoglycemia,
fibromyalgia,
etc.
- Cerebral hypo
perfusion
- CVS causes
- Seated or
standing
- Transient
symptoms
- Blurring vision
or blackout
- Any position
- Big Three
Psychiatric
- Psychiatric or
stressor
history
- Non
physiological
course
- No
neurological
abnormalities
15. T I T R A T E
Timing Triggering
Target
Examination
Am Fam Physician. 2017 Feb 1;95(3):154-162
Practical Approach to vertigo
16. History
• How can patient describe it?
• Onset (sudden or slow)
• Course (episodic or continuous)
• Duration (seconds, minutes or hours)
• Severity
• Provoking, aggravating factors
• Associated symptoms (CNS symptoms, hearing symptoms)
• Risk factors for Cardiovascular disease
• Past & Drug history.
Timing
Triggering
Am Fam Physician. 2017 Feb 1;95(3):154-162
18. - Benign paroxysmal
positional Vertigo
- Vestibular neuritis
- Labyrinthitis
- Meniere disease
- Vestibular migraine
- Brainstem infarction
- Cerebellar infarction or
hemorrhage
Recurrent, brief (seconds)
Single episode, acute onset, lasts days
(more prolonged and severe episodes)
Recurrent, typically last hours but can be
briefer
History of Migraine
Single or recurrent, last several minutes
to hours
Timing
19. Triggering & Suggestive history
- Benign paroxysmal
positional Vertigo
- Vestibular neuritis
- Labyrinthitis
- Meniere disease
- Vestibular migraine
- Brainstem infarction
- Cerebellar infarction or
hemorrhage
- Perilymphatic fistula
Initiated by movement of head & neck
- Recent viral symptoms
- Labyrinthitis is same but associated
with unilat. hearing symptoms
Spontaneous, Unilateral tinnitus,
hearing loss, ear fullness
History of Migraine
Older patient, vascular risk factors, and
or cervical trauma, neurological
symptoms (Ds)
Coughing, sneezing, exertion, or loud
noises (Tullio phenomenon)
20. Target Examination
• Vital Signs :
BP (sitting & lying), pulse (A.F)
• CNS exam:
Cranial nerves, Sensory, Motor, reflexes,
Cerebellar signs, Romberg test.
• CVS exam: Auscultation for A.S
• Carotid bruit
• Ear exam: Otoscopy, Hearing assessment(Weber’s Test, Rinne Test
• Dix-Hallpike maneuver &/or Supine head roll test Vs HINTS exam
21. - Imbalance with open eye , then there may be a
problem with the cerebellum.
- Imbalance with closed eye, then the problem
may lie in the vestibular or proprioceptive
systems
Balance and Gait
22. - The otoscopic examination provides
evidence of otitis media, for vesicles
(i.e., herpes zoster oticus [Ramsay
Hunt syndrome]) or cholesteatoma.
- Unilateral sensorineural hearing loss
suggests a peripheral lesion (eg,
Meniere disease).
Ear Examination
23. How does nystagmus help in
differentiating central from peripheral
vertigo ?
24. None 2-30 sec
> 30 sec 5-30 sec
No Yes
Usually absent Usually present
No suppression
- Bidirectional
- Vertical or horizontal
suppression
- Unidirectional
- Horizontal or rotatory
Central PeripheralFeature
Latency1
Duration
Fatigability2
Vertigo
Fixation
Direction
1 Time between attaining head position and onset of symptoms.
2 Disappearance of symptoms with maintenance of offending position.
3 Lessening of symptoms with repeated trials.
Habituation3 No Yes
25.
26. Sensitivity of 82% and a specificity of 71% in
posterior canal BPPV
Dix-Hallpike maneuver
Am J Otolaryngol. 2006;27:173-178.
Nystagmus from the Dix- Hallpike test in posterior
semicircular canal BPPV is upbeating & torsional.
27. Supine roll test
DIAGNOSIS OF LATERAL (HORIZONTAL) SEMICIRCULAR CANAL BPPV:
If the patient has a history compatible with BPPV and the Dix- Hallpike test
exhibits horizontal or no nystagmus, the clinician should perform, or refer to a
clinician who can perform, a supine roll test to assess for lateral semicircular
canal BPPV.
Clinical Practice Guideline: Benign Paroxysmal Positional Vertigo (Update)
Otolaryngology– Head and Neck Surgery 2017, Vol. 156(3S) S1– S47
28. Head Impulse
test
Nystagmus
Test of Skew
HINTS Examination
In stroke it is : INFARCT
Impulse Normal
Fast Phase Alternating
Refixation on Cover Test
Any positive one points
to stroke in AVS
29. Benign Examination : SEND HIM ON HOME
- Straight Eyes (normal eye alignment, esp. vertical)
- No Deafness (no moderate to severe hearing loss)
- Head Impulse Misses (unilaterally abnormal HIT)
- One-way Nystagmus (unidirectional, horizontal)
- Healthy Otic and Mastoid Examination (pearly; no pimples, pus,
perforation, or pain on palpation)
30. Investigations
- No routine investigations
But if indicated you can ask for
- CBC, TFT, KFT.
- C.T, MRI.
- ECG, Cardiac monitoring, carotid doppler .
- Audiometry
32. Treatment BPPV
Epley maneuver
- Clinicians should treat, or refer to a clinician who
can treat, patients with posterior canal BPPV.
Strong recommendation 1
- The success rate of the Epley maneuver is ~ 80% 2
1-Clinical Practice Guideline: Benign Paroxysmal Positional Vertigo (Update) Otolaryngology– Head and Neck Surgery 2017, Vol. 156(3S) S1– S47
2-emedicine.medscape.com/article/791414-treatment
When not to do it?
35. Treatment of vestibular neuritis
- In 50% of patients, the underlying nerve damage may take two months to
Resolve
- Reassurance, explanation, and advice are essential, in combination with
symptomatic treatment for the first few days .
- Antiemetics and antinausea medications should be used for no more than three
days because of their effects in blocking central compensation
- Although systemic corticosteroids have been recommended as a treatment for
vestibular neuritis, there is insufficient evidence for their routine use.
- Antiviral medications are ineffective.
Am Fam Physician. 2017 Feb 1;95(3):154-162
36. Treatment of vestibular neuritis
Medication Dosage
Antiemetics
Metoclopramide
Prochlorperazine
5 to 10 mg orally every 6 hours, or 5 to 10 mg slowly IV every 6 hours
5 to 10 mg orally or IM every 6 to 8 hours
Antihistamines
Dimenhydrinate
Meclizine
Promethazine
50 mg orally every 6 hours
12.5 to 50 mg orally every 4 to 8 hours
25 mg every 6 hours orally, IM, or rectally every 4 to 12 hours
Benzodiazepines
Diazepam (Valium)
Lorazepam (Ativan)
2 to 10 mg orally or IV every 4 to 8 hours
1 to 2 mg orally every 4 hours
Am Fam Physician. 2017 Feb 1;95(3):154-162
37. Betahistadine in vertigo
- This observational study found that treatment of vestibular vertigo with
betahistine (dosed at 48 mg/day) appeared to be effective in reducing vertigo-
associated symptoms in a routine outpatient clinical setting.
- Betahistine was well tolerated when administered at 48 mg/day for 2 months,
and should be considered as a good therapy option by physicians treating
vertigo
- Low quality evidence suggests that in patients suffering from vertigo from
different causes there may be a positive effect of betahistine in terms of
reduction in vertigo symptoms.
•First published: 21 June 2016
•Editorial Group: Cochrane ENT Group
•DOI: 10.1002/14651858.CD010696.pub2
•PLOS ONE | https://doi.org/10.1371/journal.pone.0174114 March 30, 2017