Viscera is an important evidence in forensic toxicology to find out the poison used to kill a person. But how to preserve this viscera?
Read in this ppt!
this presentation deals with the forensic aspects of identification using various 2D & 3D techniques, including the facial approximation methods.....
The efforts of Dr. R V Singh and Ms. Alka Gupta in making of this presentation is appreciated..
Viscera is an important evidence in forensic toxicology to find out the poison used to kill a person. But how to preserve this viscera?
Read in this ppt!
this presentation deals with the forensic aspects of identification using various 2D & 3D techniques, including the facial approximation methods.....
The efforts of Dr. R V Singh and Ms. Alka Gupta in making of this presentation is appreciated..
whenever and wherever a Disaster takes place in the form of Tsunami, Earthquake, Terrorist attack or Bomb blast the bodies which we get at the crime scene are either damaged or sometimes face cannot be identified.
Portrait Parle via Bertillon System By G S ShaktawatG.S Shaktawat
The individualization of the human is very hard thing from the ages. People had done or invented certain ways for the proper individualization of the person. The Bertillon System is the first anthropological technique for individualization invented by Sir Bertillon.
This PPT contains the content mainly from the history to the decline of the Bertillon system. And the center point of the PPT is the Portrait Parle or Bertillonage.
Antropological Comparision Between Human and Non-human Skeleton RemainsG.S Shaktawat
The skeleton remains can be found at the scene of crime and to confirm the skeleton belongs to human or non human is very important. And for this one should able to do the camparision among them and should drive the investigation in right path. So, In this presentation you will see the some comparisions between human and non human skeleton remains,which is an important topic of the Forensic Anthropology.
VSC VIDEO SPECTRAL COMPARATAOR FORENSIC APPLICATIONS BY SHAILESH CHAUBEY STUDENT OF FORENSIC SCIENCE & CRIMINOLOGY FROM BUNDELKHAND UNIVERSITY JHANSI UTTAR PRADESH INDIA . THIS PPT SHOWS ABOUT THE FEATURES, APPLICATIONS , CASE LAWS & NEED OF VSC IN FORENSIC ASPECTS FOR DOCUMENT EXAMINATION & HANDWRITING . THIS PRESENTATION WILL HELP TO GET MORE INFORMATION ABOUT VSC BY VARIOUS SLIDES.
Fingerprint - Everything You Need To Know About FingerprintsSwaroopSonone
A detailed fingerprint presentation. Fingerprint is one of the most important criminal investigation tools due to their two significant features- uniqueness and persistence. The unique features of friction ridge skin persist from before birth, i.e. during fetal development to the decomposition after death...
whenever and wherever a Disaster takes place in the form of Tsunami, Earthquake, Terrorist attack or Bomb blast the bodies which we get at the crime scene are either damaged or sometimes face cannot be identified.
Portrait Parle via Bertillon System By G S ShaktawatG.S Shaktawat
The individualization of the human is very hard thing from the ages. People had done or invented certain ways for the proper individualization of the person. The Bertillon System is the first anthropological technique for individualization invented by Sir Bertillon.
This PPT contains the content mainly from the history to the decline of the Bertillon system. And the center point of the PPT is the Portrait Parle or Bertillonage.
Antropological Comparision Between Human and Non-human Skeleton RemainsG.S Shaktawat
The skeleton remains can be found at the scene of crime and to confirm the skeleton belongs to human or non human is very important. And for this one should able to do the camparision among them and should drive the investigation in right path. So, In this presentation you will see the some comparisions between human and non human skeleton remains,which is an important topic of the Forensic Anthropology.
VSC VIDEO SPECTRAL COMPARATAOR FORENSIC APPLICATIONS BY SHAILESH CHAUBEY STUDENT OF FORENSIC SCIENCE & CRIMINOLOGY FROM BUNDELKHAND UNIVERSITY JHANSI UTTAR PRADESH INDIA . THIS PPT SHOWS ABOUT THE FEATURES, APPLICATIONS , CASE LAWS & NEED OF VSC IN FORENSIC ASPECTS FOR DOCUMENT EXAMINATION & HANDWRITING . THIS PRESENTATION WILL HELP TO GET MORE INFORMATION ABOUT VSC BY VARIOUS SLIDES.
Fingerprint - Everything You Need To Know About FingerprintsSwaroopSonone
A detailed fingerprint presentation. Fingerprint is one of the most important criminal investigation tools due to their two significant features- uniqueness and persistence. The unique features of friction ridge skin persist from before birth, i.e. during fetal development to the decomposition after death...
QUICK guide to Skeletal System- Dr Gurjant Singh (PT)Dr. Gurjant Singh
So you have read well about human skeletal system and now just want to revise or go through it quickly? Here is the perfect one for you
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Anatomy of the pelvis, understand the clinical relevance and key landmarks,parts and function,blood and nerve supply and disorders associated with the pelvis.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
3. Introduction
Skeleton is an excellent material in living and non-living population
for genetic,anthropological,odontologic and forensic
examination.Skull and bone feature vary from male to female and
differentiation is usually based on the male features that are
typically more pronounced and marked than female features.
The human skeleton consists of both fused and individual bone.
Fused bones include those of the pelvis and the cranium. At birth a
newborn baby has approximately 300 bones, whereas on average
an adult human has 206 bones. The difference comes from a
number of small bones that fuse together during growth, such as
the sacrum and coccyx of the vertebral column.
4.
5. The determination of sex by examination of
skeleton is based up on the appearances of:
Pelvis (innominates + sacrum)
Skull (cranium + mandible)
Long bones (humerus + femur)
Sternum
Scapula
Metacarpal bones
6. Skull
The skull is a bony structure which serves as the general framework
for the head. The skull supports the structures of the face and
protects the head against injury.
Skull sub divided in to two parts:
CRANIUM
MANDIBLE
7. Skull
The features that indicates sex are:
General appearance
Supra orbital ridges
Orbits
Glabella
Zygomatic arches
Mastoid processes
External occipital protuberance
Mandible
palate
8. General appearance of skull
• Smaller
• More gracile
FEMALE
• Larger
• More rugged
MALE
9. Supra orbital ridges
This is the region directly above the orbit and nose, or the (brow ridge)
Less pronounced=female
More pronounced=male
12. Zygomatic arches
In females, the zygomatic arch is less pronounced and tends to not
extend posteriorly beyond the external auditory meatus.
In males, the zygomatic arch is more pronounced or robust, and tends
to extend posteriorly beyond the external auditory meatus.
15. Mandible
The mandible together with the
maxilla, the largest and strongest
bone of the face. It forms the
lower jaw and holds the lower
teeth in place.
The male mandible tends to
have a (square) shaped.
The female mandible tends to
have a (pointed) chin
17. Pelvis
The pelvic gridle is the most sexually dimorphic region of the
skeleton and it can be used to determine sex with a high degree
of accuracy
. The sexual dimorphism of pelvis is primarily the results of
reproductive mechanism and is not readily apparent untill
adolescence
Pelvis bone representing the union of three bones
{ilium, ischium, pubis}
18. Pelvis
Features that indicates sexes are as follows:
Pelvis as whole
Symphysis
Sub-pubic angle
Obturator foramen
Acetablulum
Greater sciatic notch
Ischipubic rami
sacro-iliac articulation
Ilium
Sacrum
Pelvic brim
19. Pelvis as whole
Male- massive, rugged, marked muscular sites.
Female- less massive, gracile, smoother.
30. Sternum
The sternum is an elongated, flattened
bone, forming the middle portion of
the thorax. Its upper end supports the
clavicles and its margins articulate with
the cartilages of the first seven pairs of
ribs.
It consists of three parts, from above
downwards.
Manubrium
Body of sternum
Xiphoid process
31. Sternum
Traits
Body
Level
manubrium
Male
The body of the sternum
is bigger and is at least
twice or more the length
of manubrium.
The upper border of the
sternum is usually at the
level of lower part of the
body of the 2nd thoracic
vertebrae.
Somewhat smaller.
Female
The body of the sternum
is shorter and is less
than twice the length of
the manubrium.
The upper border of the
sternum is usually at the
level of lower part of the
body of the 3rd thoracic
vertebrae.
Somewhat bigger.
