Dental plaque is a biofilm that forms on teeth and consists of bacteria, host cells, and an extracellular matrix. It exists as both supragingival plaque above the gums and subgingival plaque below the gums. Subgingival plaque has a different composition than supragingival plaque due to the anaerobic environment below the gums. Plaque forms through an initial adhesion of bacteria to the acquired pellicle on the tooth surface followed by colonization and maturation of the biofilm. Factors such as surface topography, individual variables, and gingival inflammation can influence plaque formation.
This document discusses various tests that can be used to measure dental caries activity and susceptibility. It describes tests such as the Lactobacillus colony count test, Snyder test, Alben's test, swab test, reductase test, enamel solubility test, and saliva flow test. These tests measure factors like the number of acid-producing bacteria in saliva, ability of salivary bacteria to produce acid from carbohydrates, changes in saliva pH, and saliva flow rate, which can help indicate a person's risk of developing new dental caries.
Dental plaque is a microbial biofilm that forms on teeth. It is composed of bacteria, salivary components, food debris and other substances. As plaque matures over time, initially harmless streptococci are replaced with more pathogenic gram-negative bacteria and anaerobes. Mature plaque near the gums can cause inflammation and is associated with conditions like gingivitis and periodontitis. Plaque is assessed visually using disclosing agents or tactilely with probes, and proper removal through brushing and flossing is important for oral health.
Restorative materials used in paediatric dentistrykamini singh
This document provides an overview of restorative materials used in pediatric dentistry, including recent advancements. It discusses the need for restoration in deciduous teeth and the requirements of ideal restorative materials. The main materials covered are glass ionomer cement, composite resins, and amalgam. For glass ionomer cement, it describes the composition, setting reaction, properties, classifications, and recent modifications like resin-modified, nano, and compomer versions. Recent advancements discussed include alternatives to amalgam and improvements to composites and glass ionomer cement.
The document discusses furcation, which refers to the anatomical area where tooth roots divide. It defines furcation as a complex area that is difficult to clean. Factors like root anatomy, length, and enamel projections can influence furcation involvement. Furcation involvement is graded on a scale from I-IV based on probing depth and bone loss. Nonsurgical treatments include scaling and root planing while surgical options range from osseous resection to hemisection depending on the grade. Prognosis is best when thorough diagnosis and treatment are combined with good oral hygiene.
MPDS, or myofascial pain disorder syndrome, is a pain disorder characterized by unilateral pain referred from trigger points in muscles of the head and neck. These trigger points are localized tender areas within taut muscle bands caused by micro- or macro-trauma to the musculoskeletal system. Accumulation of chemicals like lactic acid and prostaglandins in the muscles lowers the pain threshold, leading to MPDS symptoms like pain, limited jaw motion, and joint noises. Diagnosis involves assessing range of motion, palpating muscles for tenderness, and grading joint clicks. Treatment aims to inactivate trigger points, prevent recurrence, and correct perpetuating factors through therapies like physical modalities, anesthesia, pharmacotherapy, and occasionally
This document discusses Necrotizing Ulcerative Gingivitis (NUG), also known as trench mouth. It defines NUG as a microbial disease of the gingiva caused by an impaired host response. Key clinical features include necrosis of gingival tissue and pain. Diagnosis is based on these clinical findings and microscopic examination. Management involves reducing the microbial load, removing necrotic tissue, treating any systemic conditions, and supportive periodontal therapy. Prognosis is generally good with treatment but recurrence is possible without ongoing maintenance of oral hygiene.
A absolutely minimalist way to describe each and every diagnostic aid in the beautiful stream of endodontics.
one has to understand the topic by going through the bible, "Grossman 13th Edition" along with the slides I've created.
Hope this helps.
by Dr. Ishaan Adhaulia
This document discusses irrigation in endodontics. It provides an introduction to irrigation solutions and devices used, challenges of irrigation, and recent advances. It describes the ideal characteristics of endodontic irrigants and commonly used solutions such as sodium hypochlorite. Sodium hypochlorite is the current irrigant of choice and its properties, concentrations, effects on dentin, and safety considerations are discussed in detail. The document concludes by emphasizing the importance of irrigation in endodontic treatment.
This document discusses various tests that can be used to measure dental caries activity and susceptibility. It describes tests such as the Lactobacillus colony count test, Snyder test, Alben's test, swab test, reductase test, enamel solubility test, and saliva flow test. These tests measure factors like the number of acid-producing bacteria in saliva, ability of salivary bacteria to produce acid from carbohydrates, changes in saliva pH, and saliva flow rate, which can help indicate a person's risk of developing new dental caries.
Dental plaque is a microbial biofilm that forms on teeth. It is composed of bacteria, salivary components, food debris and other substances. As plaque matures over time, initially harmless streptococci are replaced with more pathogenic gram-negative bacteria and anaerobes. Mature plaque near the gums can cause inflammation and is associated with conditions like gingivitis and periodontitis. Plaque is assessed visually using disclosing agents or tactilely with probes, and proper removal through brushing and flossing is important for oral health.
Restorative materials used in paediatric dentistrykamini singh
This document provides an overview of restorative materials used in pediatric dentistry, including recent advancements. It discusses the need for restoration in deciduous teeth and the requirements of ideal restorative materials. The main materials covered are glass ionomer cement, composite resins, and amalgam. For glass ionomer cement, it describes the composition, setting reaction, properties, classifications, and recent modifications like resin-modified, nano, and compomer versions. Recent advancements discussed include alternatives to amalgam and improvements to composites and glass ionomer cement.
The document discusses furcation, which refers to the anatomical area where tooth roots divide. It defines furcation as a complex area that is difficult to clean. Factors like root anatomy, length, and enamel projections can influence furcation involvement. Furcation involvement is graded on a scale from I-IV based on probing depth and bone loss. Nonsurgical treatments include scaling and root planing while surgical options range from osseous resection to hemisection depending on the grade. Prognosis is best when thorough diagnosis and treatment are combined with good oral hygiene.
MPDS, or myofascial pain disorder syndrome, is a pain disorder characterized by unilateral pain referred from trigger points in muscles of the head and neck. These trigger points are localized tender areas within taut muscle bands caused by micro- or macro-trauma to the musculoskeletal system. Accumulation of chemicals like lactic acid and prostaglandins in the muscles lowers the pain threshold, leading to MPDS symptoms like pain, limited jaw motion, and joint noises. Diagnosis involves assessing range of motion, palpating muscles for tenderness, and grading joint clicks. Treatment aims to inactivate trigger points, prevent recurrence, and correct perpetuating factors through therapies like physical modalities, anesthesia, pharmacotherapy, and occasionally
This document discusses Necrotizing Ulcerative Gingivitis (NUG), also known as trench mouth. It defines NUG as a microbial disease of the gingiva caused by an impaired host response. Key clinical features include necrosis of gingival tissue and pain. Diagnosis is based on these clinical findings and microscopic examination. Management involves reducing the microbial load, removing necrotic tissue, treating any systemic conditions, and supportive periodontal therapy. Prognosis is generally good with treatment but recurrence is possible without ongoing maintenance of oral hygiene.
A absolutely minimalist way to describe each and every diagnostic aid in the beautiful stream of endodontics.
one has to understand the topic by going through the bible, "Grossman 13th Edition" along with the slides I've created.
Hope this helps.
by Dr. Ishaan Adhaulia
This document discusses irrigation in endodontics. It provides an introduction to irrigation solutions and devices used, challenges of irrigation, and recent advances. It describes the ideal characteristics of endodontic irrigants and commonly used solutions such as sodium hypochlorite. Sodium hypochlorite is the current irrigant of choice and its properties, concentrations, effects on dentin, and safety considerations are discussed in detail. The document concludes by emphasizing the importance of irrigation in endodontic treatment.
To sum up, the risk/benefit ratio should be always weighed before prescribing antibiotics.
Appropriately selected patients will benefit from systemically administered antibiotics.
A restrictive and conservative use of antibiotics is highly recommended in endodontic practice, but indiscriminate use is contrary to sound clinical practice
Future generations will thank us for today’s conscientious and judicious use of antibiotics
This document discusses the potential for a dental caries vaccine. It begins by defining dental caries and explaining why it is a major public health problem. It then covers how the immune system works and classifications of immunity. Key aspects of the microbiology of dental caries are explained, focusing on Streptococcus mutans and its antigenic determinants. The document discusses the need for a caries vaccine, potential routes of administration including mucosal and systemic routes, and advantages and disadvantages of passive immunization approaches. It concludes by considering the public health perspective on a potential caries vaccine and analyzing whether it could help reduce the global burden of dental caries.
1. Orthodontic tooth movement occurs through remodeling of the alveolar bone in response to prolonged mechanical forces on teeth. Bone resorbs on the pressure side and forms on the tension side of the periodontal ligament.
2. Physiologic tooth movements include eruption, drift, and minor movements during mastication. Eruption occurs through growth of the root and forces from the periodontal ligament.
3. When forces are within physiologic limits, tooth movement occurs through frontal resorption on the pressure side and bone formation on the tension side. Excessive forces cause hyalinization and undermining resorption.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The document defines and describes periodontal pockets. It notes that periodontal pockets can be classified based on their location relative to the alveolar bone as either suprabony or infrabony. Suprabony pockets have bone loss horizontally while infrabony pockets have bone loss vertically. The document also discusses the pathogenesis of pocket formation, clinical features, histopathology, and diagnosis and probing of periodontal pockets.
The document discusses various acute gingival conditions including necrotizing ulcerative gingivitis, acute herpetic gingivostomatitis, thermal/chemical gingivostomatitis, pericoronitis, and gingival abscess. It provides details on the etiology, clinical features, diagnosis, and treatment approaches for each condition. The conditions can cause pain, ulceration and necrosis of gingival tissues if left untreated.
Dr. Gopika Sukumaran provides post-operative instructions for patients after various dental treatments. After deep scaling, patients may experience discomfort, tooth sensitivity, bleeding, and appearance changes as the gums heal over the next few days. Following scaling and root planing, patients should not smoke, apply ice, rinse with salt water, and see their dentist for a follow up cleaning in 6 weeks. For fillings, patients should avoid hard foods and be careful not to bite their lip or tongue if numb. After extractions, patients should bite on gauze, avoid rinsing or sucking for 24 hours, and then begin gentle rinsing and a soft diet.
Certains medications have been associated with gingival enlargement.
the seminar gives a complete analysis of etilogy and pathogenesis involved in digo as well as sequlae of it
This document describes a case report of cracked tooth syndrome (CTS) in an unrestored maxillary premolar. A 22-year-old female patient reported discomfort when chewing soft foods with her maxillary left premolar. Clinical examinations and diagnostic tests revealed a crack on the occlusal surface. Banding the tooth eliminated the symptoms, confirming a diagnosis of CTS. After removing the crack, the tooth was restored with a direct composite to successfully treat the patient's CTS.
This document discusses the history, definition, etiology, clinical characteristics, diagnostic methods, and treatment of myofascial pain dysfunction syndrome (MPDS). Some key points:
- MPDS is a pain disorder caused by trigger points in the muscles of mastication that refer pain to the head and neck. It is the most common cause of masticatory pain.
- Etiology may include occlusal factors, prosthetic problems, malocclusion, psychophysiologic factors, and trauma.
- Clinical characteristics include pain in the head/neck, limited jaw motion, joint noises, and tender muscles.
- Treatment involves a multidisciplinary approach including medications, trigger point injections, physical
Diagnosis Of Pulpal Pathology In PedodonticsDr. Shirin
This document provides an overview of dental pulp and classifications of pulpal diseases. It discusses the characteristics and clinical findings of normal pulp, reversible pulpitis, irreversible pulpitis, pulpal necrosis, and other conditions. A variety of diagnostic procedures and tests are also described, including reviewing history, clinical examination, percussion, radiographs, as well as newer pulp testing methods like laser Doppler flowmetry and pulse oximetry. The conclusion emphasizes the importance of gathering all available information to make an accurate diagnosis prior to providing endodontic treatment or other dental procedures.
The document summarizes the biology of tooth movement during orthodontic treatment. It discusses how application of force leads to bone remodeling through pressure and tension on the periodontal ligament. Optimal force causes bone resorption on the pressure side and deposition on the tension side through cellular processes. Tooth movement occurs in initial, lag, and post-lag phases as the hyalinized tissue is removed and bone remodeling allows for further movement.
This document discusses trauma from occlusion (TFO). It begins by defining TFO as pathologic alterations or adaptive changes that develop in the periodontium as a result of undue force from chewing muscles. It describes primary TFO resulting from sudden impacts and secondary TFO from gradual changes that occur with reduced bone support. Clinical features include tooth pain and mobility. Radiographic features include widened ligament space and buttressing bone. Treatment focuses on reducing tooth mobility, eliminating prematurities, and using splints. While TFO alone may increase mobility, inflammation is required for attachment loss.
This document discusses methods for achieving isolation during dental procedures. It describes direct isolation techniques like rubber dams and cotton rolls, as well as indirect methods like patient positioning and local anesthesia. Rubber dams provide a dry, clean operating field but can be time-consuming for patients. The document outlines different types of rubber dams, clamps, frames and other accessories needed and provides guidelines on their proper use to maximize isolation and patient comfort. Maintaining a dry environment is important for restorative procedures and materials.
This document provides an overview of dental plaque, including its definition, structure, composition, formation process, and role in periodontal diseases. It discusses how plaque begins as a biofilm that forms on teeth, consisting primarily of bacteria embedded in an extracellular matrix. Over time, the plaque matures as early colonizing bacteria prepare the surface for secondary colonizers, causing the biofilm to shift from aerobic to anaerobic organisms. Mature plaque is associated with periodontal diseases as it grows below the gingival margin. The document outlines the key stages and microbial changes involved in dental plaque formation and maturation.
This document discusses calcium hydroxide, including its classification, properties, mechanisms of action, and applications. Calcium hydroxide can be classified based on setting time or mechanism of setting. It has high pH and alkalinity which provides its therapeutic effects such as antibacterial action and stimulation of hard tissue formation. Its main applications include pulp capping, pulpotomy, apexification, and as an intracanal medicament. It promotes healing through formation of a zone of coagulation necrosis followed by a dentinal bridge. Overall, calcium hydroxide is a widely used material in endodontics due to its biocompatibility and ability to stimulate hard tissue repair.
This document discusses aggressive periodontitis, a rare and severe form of periodontitis. It is characterized by early onset, rapid progression, and familial aggregation. There are two main types: localized aggressive periodontitis, which mainly affects first molars and incisors, and generalized aggressive periodontitis, which affects at least three teeth across the mouth. Risk factors include certain bacteria like Aggregatibacter actinomycetemcomitans, genetic factors, and immune system abnormalities. The document provides details on the clinical features, causes, and differences between the chronic and aggressive forms of periodontitis.
Tooth mobility refers to loose teeth that can move within their sockets. It is classified on a scale of 0 to 3 based on the degree of horizontal and vertical movement. Physiologic mobility of about 0.25mm is normal, while pathologic mobility over 1mm indicates loose teeth from periodontal disease or trauma. Periodontal disease is a primary cause as it leads to loss of attachment and bone supporting the teeth. Treatment involves splinting loose teeth together, replacing missing teeth, and correcting occlusal surfaces to reduce excessive forces. For advanced periodontal cases, extraction may be necessary.
This document discusses dental plaque and the role of bacteria in periodontal diseases. It begins by describing how the oral cavity is colonized by bacteria from birth and how plaque forms on teeth. Plaque is made up of over 500 types of bacteria embedded in an extracellular matrix. The document then discusses plaque structure and composition, the diversity of surfaces in the oral cavity that bacteria can adhere to, and factors that influence individual plaque formation. It describes the ultrastructure of plaque formation over time, as early colonizers attach followed by maturation into a biofilm. Physiological properties and growth dynamics of plaque are also summarized.
This document discusses dental plaque, including its definition, classification, composition, and development. It defines dental plaque as a soft deposit that adheres to teeth and consists of bacteria embedded in an extracellular matrix. Plaque is classified based on location, such as supragingival vs subgingival. It has both bacterial and non-bacterial components, with bacteria making up 70-80% of the solid content. Plaque develops first through the formation of a salivary pellicle on the tooth surface, followed by initial bacterial attachment and colonization by primary colonizers like streptococci. Over time, secondary colonizers adhere and plaque matures into a biofilm.
To sum up, the risk/benefit ratio should be always weighed before prescribing antibiotics.
Appropriately selected patients will benefit from systemically administered antibiotics.
A restrictive and conservative use of antibiotics is highly recommended in endodontic practice, but indiscriminate use is contrary to sound clinical practice
Future generations will thank us for today’s conscientious and judicious use of antibiotics
This document discusses the potential for a dental caries vaccine. It begins by defining dental caries and explaining why it is a major public health problem. It then covers how the immune system works and classifications of immunity. Key aspects of the microbiology of dental caries are explained, focusing on Streptococcus mutans and its antigenic determinants. The document discusses the need for a caries vaccine, potential routes of administration including mucosal and systemic routes, and advantages and disadvantages of passive immunization approaches. It concludes by considering the public health perspective on a potential caries vaccine and analyzing whether it could help reduce the global burden of dental caries.
1. Orthodontic tooth movement occurs through remodeling of the alveolar bone in response to prolonged mechanical forces on teeth. Bone resorbs on the pressure side and forms on the tension side of the periodontal ligament.
2. Physiologic tooth movements include eruption, drift, and minor movements during mastication. Eruption occurs through growth of the root and forces from the periodontal ligament.
3. When forces are within physiologic limits, tooth movement occurs through frontal resorption on the pressure side and bone formation on the tension side. Excessive forces cause hyalinization and undermining resorption.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The document defines and describes periodontal pockets. It notes that periodontal pockets can be classified based on their location relative to the alveolar bone as either suprabony or infrabony. Suprabony pockets have bone loss horizontally while infrabony pockets have bone loss vertically. The document also discusses the pathogenesis of pocket formation, clinical features, histopathology, and diagnosis and probing of periodontal pockets.
The document discusses various acute gingival conditions including necrotizing ulcerative gingivitis, acute herpetic gingivostomatitis, thermal/chemical gingivostomatitis, pericoronitis, and gingival abscess. It provides details on the etiology, clinical features, diagnosis, and treatment approaches for each condition. The conditions can cause pain, ulceration and necrosis of gingival tissues if left untreated.
Dr. Gopika Sukumaran provides post-operative instructions for patients after various dental treatments. After deep scaling, patients may experience discomfort, tooth sensitivity, bleeding, and appearance changes as the gums heal over the next few days. Following scaling and root planing, patients should not smoke, apply ice, rinse with salt water, and see their dentist for a follow up cleaning in 6 weeks. For fillings, patients should avoid hard foods and be careful not to bite their lip or tongue if numb. After extractions, patients should bite on gauze, avoid rinsing or sucking for 24 hours, and then begin gentle rinsing and a soft diet.
Certains medications have been associated with gingival enlargement.
the seminar gives a complete analysis of etilogy and pathogenesis involved in digo as well as sequlae of it
This document describes a case report of cracked tooth syndrome (CTS) in an unrestored maxillary premolar. A 22-year-old female patient reported discomfort when chewing soft foods with her maxillary left premolar. Clinical examinations and diagnostic tests revealed a crack on the occlusal surface. Banding the tooth eliminated the symptoms, confirming a diagnosis of CTS. After removing the crack, the tooth was restored with a direct composite to successfully treat the patient's CTS.
This document discusses the history, definition, etiology, clinical characteristics, diagnostic methods, and treatment of myofascial pain dysfunction syndrome (MPDS). Some key points:
- MPDS is a pain disorder caused by trigger points in the muscles of mastication that refer pain to the head and neck. It is the most common cause of masticatory pain.
- Etiology may include occlusal factors, prosthetic problems, malocclusion, psychophysiologic factors, and trauma.
- Clinical characteristics include pain in the head/neck, limited jaw motion, joint noises, and tender muscles.
- Treatment involves a multidisciplinary approach including medications, trigger point injections, physical
Diagnosis Of Pulpal Pathology In PedodonticsDr. Shirin
This document provides an overview of dental pulp and classifications of pulpal diseases. It discusses the characteristics and clinical findings of normal pulp, reversible pulpitis, irreversible pulpitis, pulpal necrosis, and other conditions. A variety of diagnostic procedures and tests are also described, including reviewing history, clinical examination, percussion, radiographs, as well as newer pulp testing methods like laser Doppler flowmetry and pulse oximetry. The conclusion emphasizes the importance of gathering all available information to make an accurate diagnosis prior to providing endodontic treatment or other dental procedures.
The document summarizes the biology of tooth movement during orthodontic treatment. It discusses how application of force leads to bone remodeling through pressure and tension on the periodontal ligament. Optimal force causes bone resorption on the pressure side and deposition on the tension side through cellular processes. Tooth movement occurs in initial, lag, and post-lag phases as the hyalinized tissue is removed and bone remodeling allows for further movement.
This document discusses trauma from occlusion (TFO). It begins by defining TFO as pathologic alterations or adaptive changes that develop in the periodontium as a result of undue force from chewing muscles. It describes primary TFO resulting from sudden impacts and secondary TFO from gradual changes that occur with reduced bone support. Clinical features include tooth pain and mobility. Radiographic features include widened ligament space and buttressing bone. Treatment focuses on reducing tooth mobility, eliminating prematurities, and using splints. While TFO alone may increase mobility, inflammation is required for attachment loss.
This document discusses methods for achieving isolation during dental procedures. It describes direct isolation techniques like rubber dams and cotton rolls, as well as indirect methods like patient positioning and local anesthesia. Rubber dams provide a dry, clean operating field but can be time-consuming for patients. The document outlines different types of rubber dams, clamps, frames and other accessories needed and provides guidelines on their proper use to maximize isolation and patient comfort. Maintaining a dry environment is important for restorative procedures and materials.
This document provides an overview of dental plaque, including its definition, structure, composition, formation process, and role in periodontal diseases. It discusses how plaque begins as a biofilm that forms on teeth, consisting primarily of bacteria embedded in an extracellular matrix. Over time, the plaque matures as early colonizing bacteria prepare the surface for secondary colonizers, causing the biofilm to shift from aerobic to anaerobic organisms. Mature plaque is associated with periodontal diseases as it grows below the gingival margin. The document outlines the key stages and microbial changes involved in dental plaque formation and maturation.
This document discusses calcium hydroxide, including its classification, properties, mechanisms of action, and applications. Calcium hydroxide can be classified based on setting time or mechanism of setting. It has high pH and alkalinity which provides its therapeutic effects such as antibacterial action and stimulation of hard tissue formation. Its main applications include pulp capping, pulpotomy, apexification, and as an intracanal medicament. It promotes healing through formation of a zone of coagulation necrosis followed by a dentinal bridge. Overall, calcium hydroxide is a widely used material in endodontics due to its biocompatibility and ability to stimulate hard tissue repair.
This document discusses aggressive periodontitis, a rare and severe form of periodontitis. It is characterized by early onset, rapid progression, and familial aggregation. There are two main types: localized aggressive periodontitis, which mainly affects first molars and incisors, and generalized aggressive periodontitis, which affects at least three teeth across the mouth. Risk factors include certain bacteria like Aggregatibacter actinomycetemcomitans, genetic factors, and immune system abnormalities. The document provides details on the clinical features, causes, and differences between the chronic and aggressive forms of periodontitis.
Tooth mobility refers to loose teeth that can move within their sockets. It is classified on a scale of 0 to 3 based on the degree of horizontal and vertical movement. Physiologic mobility of about 0.25mm is normal, while pathologic mobility over 1mm indicates loose teeth from periodontal disease or trauma. Periodontal disease is a primary cause as it leads to loss of attachment and bone supporting the teeth. Treatment involves splinting loose teeth together, replacing missing teeth, and correcting occlusal surfaces to reduce excessive forces. For advanced periodontal cases, extraction may be necessary.
This document discusses dental plaque and the role of bacteria in periodontal diseases. It begins by describing how the oral cavity is colonized by bacteria from birth and how plaque forms on teeth. Plaque is made up of over 500 types of bacteria embedded in an extracellular matrix. The document then discusses plaque structure and composition, the diversity of surfaces in the oral cavity that bacteria can adhere to, and factors that influence individual plaque formation. It describes the ultrastructure of plaque formation over time, as early colonizers attach followed by maturation into a biofilm. Physiological properties and growth dynamics of plaque are also summarized.
This document discusses dental plaque, including its definition, classification, composition, and development. It defines dental plaque as a soft deposit that adheres to teeth and consists of bacteria embedded in an extracellular matrix. Plaque is classified based on location, such as supragingival vs subgingival. It has both bacterial and non-bacterial components, with bacteria making up 70-80% of the solid content. Plaque develops first through the formation of a salivary pellicle on the tooth surface, followed by initial bacterial attachment and colonization by primary colonizers like streptococci. Over time, secondary colonizers adhere and plaque matures into a biofilm.
This document summarizes a seminar presentation on dental plaque as an oral biofilm. It defines plaque, describes its structure and composition, and explains the process of plaque formation. Plaque is defined as a bacterial biofilm that adheres to tooth surfaces. It has a stratified organization and is composed of bacteria, water, extracellular matrix, and host cells. Plaque formation begins with the development of an acquired pellicle on the tooth surface, which bacteria then attach to initially through non-specific interactions. This leads to the development of dental biofilm.
Dental plaque is a biofilm that forms on teeth and consists of bacteria, salivary proteins, and food debris. It begins forming within 1 minute of tooth eruption as the pellicle layer develops. Early colonizing bacteria like Streptococcus attach within hours and begin biofilm maturation. The biofilm composition changes over days as more gram-negative and anaerobic bacteria colonize. Without removal, plaque accumulation leads to gingivitis within a few days. Mature biofilm develops complex microbial communities and interactions that can promote periodontal disease if left unchecked.
Dental plaque is a biofilm that forms on teeth and consists of bacteria embedded in an extracellular matrix. It develops in stages, beginning with the formation of a protein pellicle layer on the tooth surface within seconds of cleaning. Initial colonizers like streptococci then adhere to the pellicle. Secondary colonization involves more species adhering directly or co-aggregating with initial colonizers. Co-aggregation involves specific adhesins on bacteria binding together different species in complex biofilms. The plaque matures into distinct supragingival and subgingival biofilms as the environment changes below the gumline.
Dental plaque biofilm cannot be eliminated permanently.
However, the pathogenic nature of the dental plaque biofilm can be reduced by reducing the bio burden (total microbial load and different pathogenic isolates within that dental plaque biofilm) and maintaining a normal flora with appropriate oral hygiene methods that include daily brushing, flossing and rinsing with antimicrobial mouth rinses.
This can result in the prevention or management of the associated squeal, including the development of periodontal diseases and possibly the impact of periodontal diseases on specific systemic disorders.
This document discusses plaque as a biofilm and the microbiology of periodontal diseases. It begins by introducing the complex microbial flora that inhabits the oral cavity. A key point is that while most of these microbes coexist harmlessly with the host, a subset of organisms can lead to periodontal diseases either through overgrowth or new pathogenic properties. The document then examines historical and modern evidence that supports the infectious nature of periodontal diseases. It discusses the unique features of periodontal infections as biofilms outside of the body on tooth surfaces. Finally, it reviews the current understanding of suspected periodontal pathogens and their role in destructive periodontal disease.
This document provides an overview of dental plaque, including its:
1) Classification, composition, structure and formation as a biofilm on teeth. Dental plaque is made up of bacteria and an intercellular matrix that accumulates on teeth.
2) Role in dental diseases like caries and periodontitis. The specific bacteria present in plaque influence which diseases may develop.
3) Methods of detection and removal, which are important for oral health maintenance and disease prevention. Effective plaque removal is needed to prevent its buildup and the diseases it can cause.
The document discusses dental plaque, which represents a biofilm that forms on teeth. It begins by describing how plaque formation starts after birth as microorganisms colonize the oral cavity. Plaque is defined as a structural entity resulting from the colonization of microorganisms on tooth surfaces. Over time it can calcify to form calculus. Plaque formation involves an initial phase where a pellicle layer forms, followed by the adhesion and colonization of bacteria. As plaque matures it develops a complex structure and composition. Certain bacterial complexes like the red complex are associated with periodontal disease. The document also discusses the nonspecific and specific plaque hypotheses for the causes of periodontal disease.
This document discusses biofilms and dental plaque. It begins by defining biofilms as self-produced extracellular matrices composed of biopolymers that allow microorganisms to stick to surfaces. Biofilms are found in various environments and contain diverse microbial communities embedded in a protective glycocalyx layer. As more microbes colonize the surface, mushroom-shaped structures called microcolonies form within the biofilm. Fluid channels also develop to transport nutrients and waste. Dental plaque is a specific oral biofilm that forms on teeth and other surfaces. It has both supragingival and subgingival components composed primarily of streptococci and other bacteria. Coaggregation and coadhesion between early and late colonizers aid in plaque maturation over time
Introduction……
Uterus……..Sterile
After birth……… few facultative & aerobic microorganisms
Second day……... anaerobic
2 weeks …….. Nearly mature microbiota
> 2 years …….. 400 different spp (10 14 )
After tooth eruption …… > 500 spp.
Any individual contains ≥150 spp.
6 Ecological niches
Or
Microbial habitats within the mouth
EARLYCOLONIZERS
Dental plaque
Formation
2. Specific Plaque Hypothesis
Only certain plaque is pathogenic, and its pathogenicity depends on the presence of or increase in specific microorganisms.
This concept predicts that plaque harboring specific bacterial pathogens results in periodontal disease because these organisms produce substances that mediate the destruction of host tissues.
3. Ecological plaque hypothesis
In 1990, PD Marsh et al developed the ecologic plaque hypothesis
According to this, both the total no. of dental plaque and the specific microbial composition of plaque may contribute to the transition from health to disease.
A change in the nutrient status of a pocket or chemical and physical changes to the habitat are thus considered the primary cause for overgrowth by pathogens.
This document provides information on dental plaque, including its definition, composition, formation, and role in periodontal diseases. It defines dental plaque as a biofilm that forms on teeth and consists of bacteria, salivary and tissue components embedded in an extracellular matrix. Plaque forms in stages, beginning with the formation of a dental pellicle that bacteria then adhere to. The plaque develops over time as different bacterial species colonize. Mature plaque has a complex structure and composition. Certain complexes of bacteria in plaque are associated with periodontal health and disease. Methods for analyzing plaque include microscopy, culture, enzymatic assays, immunoassays, and nucleic acid-based techniques.
This document provides information on dental plaque, including its definition, composition, formation, and role in periodontal diseases. It defines dental plaque as a biofilm that forms on teeth and consists of bacteria, salivary and tissue components embedded in an extracellular matrix. Plaque forms in stages, beginning with the formation of a dental pellicle that bacteria then adhere to. The plaque develops over time as different bacterial species colonize. Mature plaque has a complex structure and composition. Certain complexes of bacteria in plaque are associated with periodontal health and disease. Methods for analyzing plaque include microscopy, culture, enzymatic assays, immunoassays, and nucleic acid-based techniques.
Dental plaque is a biofilm that forms on teeth and consists of a complex community of over 700 bacterial species. It is composed of 60-70% bacteria embedded in a matrix of 30-40% extracellular polymers, proteins and carbohydrates. Plaque forms in stages, beginning with the pellicle layer coating the tooth surface within hours, followed by colonization of primary colonizers like Streptococcus and Actinomyces. Secondary colonizers like Prevotella, Fusobacterium and Porphyromonas then adhere, forming the mature biofilm structure with stratified layers of cocci and rods. Plaque morphology demonstrates specific coaggregation of bacteria into corncob formations that contribute to pathogenesis of dental diseases.
This document discusses dental plaque, beginning with definitions of dental plaque, dental calculus, and materia alba. It then covers the classification, composition, and formation of plaque. Plaque is classified as supragingival or subgingival. Its organic composition includes polysaccharides, proteins, glycoproteins, and lipids, while its inorganic composition contains calcium, phosphorus, sodium, potassium, and fluoride. Plaque formation is a sequential process whereby early colonizers like Streptococcus species facilitate the later colonization of pathogens like Porphyromonas gingivalis and Treponema denticola. Biofilms provide structure and protection for the hundreds of bacterial species that comprise plaque.
The document discusses biofilms, also known as dental plaque. It defines biofilms as clusters of microorganisms embedded in a self-produced matrix on surfaces. In the oral cavity, biofilms form on teeth and gums. They begin forming within hours of birth as pioneer bacteria like Streptococcus adhere. Over days and years, the biofilm becomes more complex as more species colonize. Mature dental plaque biofilms have a layered structure and are embedded in an extracellular matrix that is resistant to removal.
1. Dental plaque is a biofilm that forms on teeth and consists of bacteria, host cells, and an extracellular matrix. It begins forming within minutes on teeth as the salivary pellicle.
2. Primary colonizers like streptococci initially adhere to the pellicle via electrostatic or hydrophobic interactions. They facilitate the adherence of secondary colonizers as plaque matures.
3. Coaggregation and coadhesion allow later colonizers like Porphyromonas gingivalis and Tannerella forsythia to join the biofilm through protein-carbohydrate interactions between species. Bacteria like Fusobacterium nucleatum act as bridges between early and late colonizers.
Dental plaque is a biofilm that forms on teeth and other oral surfaces. It is composed of bacteria embedded in an extracellular matrix. As plaque develops over time, the bacterial composition changes from primarily aerobic gram-positive bacteria to include more gram-negative and anaerobic bacteria. Plaque forms in distinct phases - initially with reversible bacterial adhesion to the acquired pellicle on the tooth surface, followed by irreversible adhesion and growth of microcolonies within the matrix. Mature plaque has a complex structure as a biofilm with water channels and bacterial clusters. Dental plaque is the primary cause of dental caries and periodontal disease.
The maxillary sinus is an air-filled space within the body of the maxilla bone. It develops from the lateral nasal wall and communicates with the nasal cavity via the middle meatus. It has a four-sided pyramid shape with four walls. Its epithelial lining contains ciliated pseudostratified columnar cells that help clear mucus and debris. The maxillary sinus serves functions like warming inhaled air, moisturizing dry climates, and protecting the brain from cold temperatures. Clinical considerations include sinusitis, fistulas, and infections of the mucoperiosteal layers.
This document provides an introduction to dental anatomy and oral histology. It discusses the number and types of both deciduous and permanent teeth. The key parts of a tooth are described including the crown, root, cementum, dentin, enamel, and pulp. The normal eruption times for both deciduous and permanent teeth are outlined. Important anatomical landmarks found on teeth such as cusps, ridges, fossae, and grooves are defined. Finally, different tooth numbering systems including universal, Palmer, and FDI are explained.
The document discusses the rationale for endodontic treatment. It begins by explaining how endodontic pathology is caused by physical, chemical, or bacterial injury to the pulp, resulting in inflammatory and immune reactions. The goal of endodontic therapy is to completely debride the root canal system and achieve a three-dimensional seal during obturation. This prevents reinfection and aids healing of periapical tissues. The document covers various theories of infection spread, microorganisms involved, routes of entry, tissue changes, inflammatory responses, and the rationale behind nonsurgical and surgical endodontic treatments.
This document summarizes various diseases of the dental pulp and periapical tissues. It describes diseases such as pulpitis, periapical periodontitis, periapical abscess, and osteomyelitis. Acute and chronic forms of each disease are discussed along with their etiology, clinical features, radiographic features, histopathological features, and treatment. Different types of pulpitis include reversible and irreversible, as well as closed and opened chronic pulpitis. Periapical diseases range from acute and chronic periapical periodontitis to periapical abscesses and cysts. Osteomyelitis can be acute, chronic suppurative, or chronic focal sclerosing. Garres oste
1. Cleaning and shaping of the root canal involves removing debris and establishing a continuously tapering canal to allow for disinfection and filling.
2. There are various techniques for cleaning and shaping including step-back, crown-down, and balanced force, each aiming to optimize the mechanical, biological and clinical objectives.
3. The techniques differ in whether they work from the apex to the crown or vice versa, and use hand or rotary instruments in various sequences to safely and effectively prepare the complex root canal system.
This document discusses cavity preparation for cast metal restorations. It defines inlays and onlays, and describes the different classes of dental casting alloys based on their composition, including gold alloys, low gold alloys, non-gold platinum alloys, nickel-chromium alloys, and castable ceramics. It outlines the principles of cavity preparation, including requirements for resistance and retention form, with features like divergent walls, line angles, and beveled margins. Proper preparation is important for the strength and fit of cast metal restorations.
This document discusses factors to consider when selecting cases for endodontic treatment. It begins by introducing the importance of proper case selection to avoid treatment failures. Key considerations for case selection include assessing the need for the tooth, its restorability, periodontal health, and the clinician's ability to perform the necessary procedures. Factors associated specifically with teeth include indications for treatment, as well as contraindications like insufficient support, improper positioning, excessive calcification or abnormal canal morphology. Patient health factors that may impact treatment include medical history, physical status, and conditions requiring antibiotic prophylaxis like cardiovascular diseases. The document provides guidelines on evaluating these case selection factors to optimize endodontic treatment outcomes.
Root canal sealers are used to fill the space between the root canal filling material and the wall of the root canal. They help seal the root canal system to prevent reinfection. Dr. Ashwini M Patil is a Reader at Navodaya dental college in Raichur who has expertise in root canal sealers.
Mercury toxicity can occur from exposure to mercury in various forms. Elemental mercury is a liquid metal that vaporizes at room temperature into an odorless gas. Inorganic mercury combines with other elements to form salts, while organic mercury combines with carbon. Dental amalgam used in fillings contains mercury. Exposure risks include inhalation of vapors during placement or removal of fillings. Mercury is a potent neurotoxin that can cross the blood-brain barrier and cause neurological and developmental effects. Symptoms of toxicity depend on the level and route of exposure, ranging from rashes to kidney damage.
Direct filling gold is the oldest restorative material used in dentistry due to its biological and mechanical properties. It exists in various forms including gold foil, electrolytic precipitate, and powdered gold. Gold foil can be cohesive or non-cohesive depending on surface contaminants. Manipulation of direct gold restorations involves degassing to remove surface gases followed by compaction. It is primarily indicated for small, non-stress bearing cavities where esthetics are not a concern due to its biocompatibility and ability to be cold welded. Disadvantages include its color, potential for increased sensitivity, and difficulty of manipulation.
This document discusses dental contacts and contours. It begins by explaining the importance of proper occlusal and proximal contacts in stabilizing teeth and resisting mesial drift. Contours on the facial, lingual, and proximal surfaces protect supporting tissues during mastication. Proper proximal contacts and embrasures are important for preventing food impaction and protecting soft tissues. The document then discusses techniques for developing correct contacts and contours during restorative procedures, including tooth separation, wedging, and matrix placement. Maintaining proper contacts and contours is important for dental and periodontal health.
Root resorption can be caused by various factors and occurs through a multistep process. It begins with injury to the protective layers of the root, followed by an inflammatory response and recruitment of cells like osteoclasts and odontoclasts that resorb the hard tissues. External root resorption includes types like surface resorption from trauma that typically repairs on its own without treatment. Diagnosis involves radiographs and other advanced imaging while the goal of treatment is to arrest the resorptive process.
This document summarizes pulpal reactions to various restorative materials and dental procedures. It discusses how microbial, physical, and chemical irritants can damage the pulp, including through dental caries, operative procedures, trauma, and restorative materials. It also describes the pulp's defensive reactions like formation of reactionary dentin, reparative dentin, and inflammation. Treatment options for vital pulp like indirect pulp capping, direct pulp capping, and medicaments are outlined, with calcium hydroxide and mineral trioxide aggregate highlighted as common capping materials that stimulate hard tissue formation.
1. Periodontal diseases can damage the pulp through microbial, physical, or chemical irritants. Microbial irritants like dental caries or periodontal infections allow bacteria to enter the pulp. Physical irritants include operative procedures, trauma, orthodontic movements, and deep periodontal curettage. Chemical irritants involve dental materials and antibacterial agents.
2. In response, the pulp attempts defense reactions like tubular sclerosis, tertiary dentin formation, and varying degrees of inflammation. Calcium hydroxide is commonly used in direct and indirect pulp capping procedures due to its ability to stimulate hard tissue formation and create an alkaline environment against bacteria. Successful outcomes depend on several factors.
NON CARIOUS LESIONS AND MANAGEMENT.pptxDentalYoutube
The document discusses various types of non-carious lesions including attrition, abrasion, abfraction, and erosion. It describes the causes and characteristics of each lesion and provides examples of cases. Treatment options are focused on removing the cause, restoring the tooth if needed, and addressing sensitivity or risk of further damage. Restorative materials suggested include composites, glass ionomers, and sometimes metal restorations depending on the location and severity of the lesion. Management involves correcting habits, protecting exposed dentin, and restoring integrity and function of the tooth.
This document provides a historical overview of endodontics from the 17th century to present day. Some key developments include Fauchard describing pulp removal in 1746, the introduction of gutta-percha as a filling material in 1847, and the discovery of X-rays in 1895 which allowed for better diagnosis and treatment planning. Over time, procedures have become more refined with the adoption of rubber dams, improved instruments, irrigants, and obturation techniques. Modern endodontics utilizes technologies like CBCT, electronic apex locators, microscopes, rotary files, ultrasonic irrigation, and biocompatible sealers to optimize outcomes.
This document discusses intracanal medicaments used in endodontic treatment. It defines intracanal medicaments as temporary placement of biocompatible medications into root canals to inhibit bacterial invasion from the oral cavity. The document outlines the history and ideal requirements of intracanal medications. It describes common medications used like chlorhexidine, formocresol, calcium hydroxide, antibiotics, steroids, and herbal options. The functions and mechanisms of these various medications are summarized.
1. There are various cavity designs for amalgam restorations depending on the location and extent of the dental caries. Cavity designs are classified based on the Black Classification system as Class I through Class VI cavities.
2. Key principles of tooth preparation for amalgam restorations include establishing an outline form that extends the cavity margins into sound tooth structure. The cavity should have a primary resistance form and features like cavosurface margins, reverse curves, and retention forms or locks to resist forces and retain the restoration.
3. Specific cavity preparations are described for different classes of cavities, including designs for single surface Class I cavities, multi-surface Class I cavities, various Class II cavity designs for proximal lesions
Air abrasion uses compressed air to propel aluminum oxide particles to remove tooth structure for restorations. It is a minimally invasive alternative to drills that causes little damage to sound tooth structures. Air abrasion works quickly without vibration, pressure, or heat compared to drills. It is well-suited for removing small areas of decay, repairing existing restorations, and preparing surfaces for bonding and sealants. Precautions include protecting the patient and dental team from abrasive particles and controlling the air pressure and distance from the tooth.
PAIN CONTROL in operative dentistry.pptxDentalYoutube
This document discusses pain control in operative dentistry. It begins with definitions of pain and classifications of pain based on duration (acute, persistent, chronic) and sensory characteristics (fast and slow pain). The neural pathways of pain and various theories of pain are described. Methods of assessing pain and factors that influence pain perception are outlined. Common causes of orofacial pain are listed along with differential diagnosis of pain. Techniques for controlling pain in restorative dentistry are provided, including local anesthesia and gaining patient confidence.
Travel Clinic Cardiff: Health Advice for International TravelersNX Healthcare
Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
Nano-gold for Cancer Therapy chemistry investigatory projectSIVAVINAYAKPK
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
Are you looking for a long-lasting solution to your missing tooth?
Dental implants are the most common type of method for replacing the missing tooth. Unlike dentures or bridges, implants are surgically placed in the jawbone. In layman’s terms, a dental implant is similar to the natural root of the tooth. It offers a stable foundation for the artificial tooth giving it the look, feel, and function similar to the natural tooth.
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort.
NAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdfRahul Sen
Time-lapse embryo monitoring is an advanced imaging technique used in IVF to continuously observe embryo development. It captures high-resolution images at regular intervals, allowing embryologists to select the most viable embryos for transfer based on detailed growth patterns. This technology enhances embryo selection, potentially increasing pregnancy success rates.
2. DEFINITION
Dental plaque
is defined clinically as a structured, resilient, yellow-
grayish substance that adheres tenaciously to the intraoral
hard surfaces, including removable and fixed
restorations.(Caranzza)
3. Material
Alba Calculus
Material Alba – soft accumulations of bacteria and tissue cells that
lack the organized structure of dental plaque & it is easily displaced
with a water spray
Calculus – is a hard deposit that form by mineralization of dental
plaque & it is generally covered by a layer of unmineralized plaque
4. Supra-
gingival
At/above gingival margin
Sub gingival
Below gingival margin &
gingival pocket epithelium
CLASSIFICATION
If in direct contact
with gingival margin
c/as MARGINAL
PLAQUE
Tooth associated
Tissue associated
5. Composed primarily of microorganisms.
>500 distinct microbial species found in
dental plaque
Composition
Non-bacterial species
-mycoplasma species
-yeasts
-protozoa
-viruses
Micro-org exist
within an
intracellular matrix
that also contains
few host cells
Epithelial
cells
Macrophag
es
Leuckocyte
s
6. SUPRA-GINGIVAL PLAQUE
Stratified organization of
multilayered accumulation
of bacterial morphocytes
Gram +ve cocci
Short rods
Gram –ve rods
Filaments & spirochetes
Predominate at
tooth surface
Predominate at
outer surface of
maute plaque
7. SUB-GINGIVAL PLAQUE
Subgingival composition differs from supragingival plaque
>Low oxidation-reduction (redox) potential with characteristics of anaerobic
environment
>Local availability of blood products
Environmental parameter differ from those of supragingival plaque
>Gingival crevice/pocket – bathed by the flow of GCF which contains many substances
that bacteria may use nutrients
>Host inflammatory cells + mediators have considerate influence on the
establishment & growth of bacteria in subgingival region
8. TOOTH ASSOCIATED SUB-GINGIVAL PLAQUE
Adheres to root Cementum.
Generally does not differ greatly
from that observed in gingivitis.
Dominance : filamentous micro-organism but cocci, rods
also occur
Gram +ve
rods, cocci
Streptococc
us mitis
S. Sanguis
Actinomyce
s viscous
A Naeslundi
Eubacterium
species
Deeper part : filamentous
Apically : virtually absent
(instead smaller micro-
organisms without proper
orientation)
Apical border of plaque mass is
separated from JE by a layer of
host leucocytes
Concentration of gram –ve rods
Thus composition of sub gingival plaque
depends upon the pocket depth
APICAL – spirochets, cocci, rods
CORONAL – more filamentous
9. TISSUE ASSOCIATED SUB-GINGIVAL PLAQUE
Lacks a definite intermicrobial matrix &
contains primarily
Gram –ve rods & cocci
Also large no of filamentous, flagellated rods
and spirochetes
Studies done
by Dibart et
al & Dzink et
al indicate
predominanc
e of
- Streptococcus oralis
- Strptococcus
intermedius
-Peptostreptococcus
micros
- Porphyromonas
Gingivalis
- Prevotella Intermedia
- Fusobaterium
nucleatum
Host tissue cells (e.g WBC’s , Epithelial cells)
10. Between subgingival plaque & tooth an electron – dense organic
material is interposed “Cuticle”
This cuticle is porbably contains the remains of the epithelial
attachment lamina, originally connecting J.E to the tooth, with
addition of the material deposited from gingival exudate.
{ Frank & Cimasoni 1970, Lie & Selvig 1975, Eide et al 1983 }
Schroeder & Listgarten 1977 – suggested the cuticle represents
a severity product of the adjacent epithelial cells
11. Thus there are 4 different subgingival ecologic niches which are
probably different in their composition
subgingival
ecologic niches
Tooth/implant
surface
Gingival
exudate fluid
medium
Surface of
epithelial cells
Superficial
portion of
the pocket
epithelium
12. Characteristic
s
Supragingival Subgingival
Location At or above the gingival margin
Marginal plaque
Below the gingival margin
Between the tooth and gingival pocket
epithelium
Gram reaction +/- Dominated by -
Morphotypes Gm +ve Cocci, short rods, -
at tooth surface
Gm-ve rods & filaments
predominate in outer
surface of mature plaque
Dominated by rods and
spirochetes
Energy
metabolism
Facultative aerobic with
some anaerobes
Dominated by anaerobes
( due to local availability of blood products ,
low red-ox potential )
Energy sources Generally ferment
carbohydrates
Many proteolytic forms
Motility Firmly adherent to plaque
matrix
Adherence less pronounced with
many motile forms
12
13. The intercellular matrix consists or organic and inorganic
materials derived from saliva, gingival crevicular fluid, and
bacterial products.
INTERCELLULAR MATRIX:
ORGANIC CONSTITUENTS INORGANIC COMPONENTS
- Albumin - Predominantly
calcium and
- Lipid material phosphorous.
- Glycoproteins - trace amt, of
sodium,
- Polysaccharides-dextran potassium, and
fluoride.
The source of inorganic constituents:
Supragingival plaque - primarily saliva
Subgingival plaque – Crevicular fluid (a serum
transudate).
The fluoride component of plaque is largely derived
from external sources such as fluoridated toothpastes,
Organic content source:
1. Albumin – GCF
2. Lipid – disrupted
membrane of acteria &
host cells
3. Glycoprotein – saliva
4. polysaccharide-
produced by bacteria
14. SITE SPECIFICITY OF PLAQUE
Marginal Plaque
Supragingival
plaque + tooth
ass. Plaque
Tissue associated
subgingival plaque
15. FORMATION OF DENTAL PLAQUE
Formation of
the pellicle.
Initial
adhesion and
attachment of
bacteria
Colonization
and plaque
maturation.
16. THE FORMATION OF THE PELLICLE &
BIOFILM ON THE TOOTH SURFACES
• All The Surfaces Of The Oral Cavity Are Coated With A Pellicle.
• Within Nanoseconds After Vigorously Polishing The Teeth, A Thin Saliva
Derived Layer, Called Acquired Pellicle (Term No Longer Used Since
Misleading), Covers The Tooth Surface.
• The Pellicle Forms By Selective Adsorption Of The Environment
Macromolecules.
• Electrostatic, Vanderwaals & Hydrophobic Forces
17. INITIALADHESION & ATTACHMENT OF BACTERIA
• Microbial Adhesion To Surfaces In An Aquatic Environment
As A Four Stages Sequences:
I. Transport To The Surface.
II. Initial Adhesion.
III. Attachment.
IV. Colonization Of The Surface And Biofilm Formation.
18. PHASE I: TRANSPORT TO THE SURFACE
-Transport Of Bacterium To The Tooth Surface.
- Random Contact May Occur, Through:
- Brownian Motion.
- Sedimentation Of Microorganisms
- Liquid Flow
- Active Bacterial Movement.
19. PHASE II : INITIALADHESION.
- Initially Adhesion Of Bacterium By Long Range
Force (50nm) Ie, Reversible.
- Later By Short Range Forces ( Less Than 2 Nm)
Ie, Irreversible.
- These Includes Electrostatic Repulsive Forces( E)
And
Vanderwals Attractive Forces ( A).
20. • PHASE III: ATTACHMENT:
- Here Firm Anchorage Between Bacterium And Surface Will Be
Established By Specific Interactions
(Covalent, Ionic, Or Hydrogen Bonding).
- This Is Followed By Direct Contact Or Bridging Through Extra
Cellular Filamentous Appendages.
- The Bonding Between Bacteria And Pellicle Is Mediated By
Specific Extrcellular Proteinaceous Components ( Adhesions) Of
The Organisms And Complementary Receptors( Ie Proteins,
Glycoprotein, Or Polysaccharides) On The Surfaces ( E.G.,
Pellicle) And Is Species Specific.
21. COLONIZATION AND PLAQUE MATURATION
• Here Early Colonizers Start Growing And Allow For Newly Formed Bacterial
Clusters Remain Attached, Micro Colonies And Biofilm Can Develop.
• New Mechanism Involved Characterized By Inter Bacterial Connections.
• 18 Genera From The Oral Cavity Shows Co Aggregation
• ( Cell-to-cell Recognition Of Genetically Distinct Partner Cell Types).
• Co Aggregation Is Interaction Of Protein And Carbohydrate Molecules Located On
The Bacterial Cell Surfaces. Hydrophobic, Electrostatic, Vanderwals Forces Also
Participates.
22. SECONDERY COLONIZATION AND PLAQUE
MATUARATION
SECONDARY COLONIZERS
PROVETELLA INTERMEDIA ,PREVOTELLA
LOESCHII,
CAPNOCYTOPHAGA,FUSOBACTERIUM
NUCLEATUM &P.GINGIVALIS
• CO-AGGREGATION
ABILITY OF DIFFERENT SPECIES & GENERA OF
PLAQUE MICROORGANISMS TO ADHERE TO
ONE OTHER
EG F. NUCLEATUM WITH S.SANGUIS
P.LOESCHII WITH A .VISCOSUS
C.OCHRACEA WITH A .VISCOSUS
F.NUCLEATUM WITH P.GINGIVALIS
F.NUCLEATUM WITH T.DENTICOLA
23. LATER STAGE COAGGREGATION BETWEEN THE
GRAM –VE SPECIES PREDOMINATE:
• F. NULEATUM WITH P. GINGIVALIS OR T.
DENTICOLA.
• “CORNCOB” FORMATION (STREPTOCOCCI WITH
B. MATRUCHOTII OR ACTINOMYCES.
• “TEST TUBE BRUSH” FILAMENTOUS TO GRAM –
VE RODS.
25. PATHOGENIC POTENTIAL OF DENTAL PLAQUE IN
PERIODONTAL DISEASES
specific
plaque
hypothesis
ecological
plaque
hypothesis
Non-
specific
plaque
hypothesis
26. FACTORS AFFECTING PLAQUE FORMATION
Topography of
supragingival plaque
Surface micro-roughness
Individual variables
Variations in dentition
Gingival inflammation
Age
27. Early Plaque Formation On Teeth Initial Growth Along The Gingival Margin And
From The Interdental Space. (Protected From Shear Forces). Later Extend In
Coronal Direction
Plaque Formation Can Also Start From Surface Irregularities Like Grooves, Cracks,
Perikymata, Or Pits
By Multiplication, The Bacteria Subsequently Spread Out From These Initial Areas
As A Relatively Even Monolayer.
28. SURFACE MICROROUGHNESS
Rough Intraoral Surfaces (E.G. Crowns, Implant Abutments, Denture Bases)
Accumulate And Retain More Plaque And Calculus In Terms Of Thickness,
Area, And Colony Forming Units. (Quirynen And Bollen ,1995).
Smoothing An Intraoral Surface Decreases The Rate Of Plaque Formation.
Threshold Level For Surface Roughness (About 0.2 µm), Above Which
Bacterial Adhesion Will Be Facilitated.
30. Noticed only minor
differences between
the groups -
Simonsson et al
( 1987)
After one day, the
heavy plaque formers
showed more plaque
with a more complex
supragingival
structure.
From 1- 14 days,
there were no
discernible
differences between
both groups, except
for a more prominent
inter microbial matrix
in the group of fast
growers.
Higher level of Gram
–ve rods in 4 day old
plaque-Zee KY et al (
1996,97)
32. VARIATION WITHIN THE DENTITION:
EARLY PLAQUE FORMATION OCCUR FASTERS IN:
• In The Lower Jaw Compare To The Upper Jaw.
• In The Molar Areas.
• On Buccal Tooth Surfaces Compare To Oral Sites.
• In The Interdental Areas Compare To Strict Buccal Or Oral
Surfaces.
QUIRYNEN M ( 1986)
33. IMPACT OF GINGIVAL INFLAMMATION:
• Plaque Formation Is More Rapid On Tooth Surfaces Facing
Inflammed Gingival Margins Than On Those Adjacent To
Healthy Gingiva
• Increase In Crevicular Fluid Production Enhances Plaque
Formation.
Ramberg P, Et Al (1994)
34. IMPACT OF PATIENTS AGE :
• Could Detect No Differences In De Nevo Plaque Formation, Either In
Amount Or In Composition Between A Group Of Young And Older
Subjects.
FRANSSON ET AL (1996)
35. 35
PERI IMPLANT PLAQUE
Mombelli etal -1988
Quirynen and Listgarten et al 1990
Apse et al 1984
Studies characterized deposits of plaque in human
peri-implant sulcus but no study has documented
the structure of supramucosal and submucosal
(peri-implant ) microbiota
However ,similarities between peri-implant and sub
gingival microbial deposits
Mombelli 1987, 1995,
Pontoreiro 1994
Also recently QUIRYNEN et al 2005
complex subgingival microbiota
( periopathogens ) is established in 1 week after
abutment insertion which increase with time
36. Characteristics of sub-gingival
flora around implant
Degree of
periodonitis in
remaining
dentition
Presence of
remaining
teeth
Smoothness of
abutments(
<0.2 um)25
times less
flora then
rough ones
37. 37
BIOFILM CONTROL
doxycycline
Authors like bonito etal 2005 confirmed
that tetracycline , minocycline most effective
in terms of PD reduction & CAL gain
locally
Under systemic antibiotics amox –metro
combination beneficial otcomes 6 months
after FMD. Also beneficaial are tetracyclines
and metronidazole haffajee, 2003, hererra
2002, cionca 2009
38. CONCLUSION
• Because Of The Various Risk Factors That Contribute To Periodontitis, It Is Possible That
There Will Be No Magic Bullet Treatment.
• It Is Also Probably True That The Underlying Cause Of Periodontitis Is Different In
Different Patients.
• For Instance, One Patients Periodontitis May Be Due To A Shift In The Oral Microflora
Due To Poor Hygiene, While Another Patients Periodontitis May Be Due To An
Underlying Genetic Abnormality That Leads To A Destructive Immune Response.
• In Light Of This, Periodontitis Is Perhaps Better Described Not As A Disease But As A
Symptom Of An Underlying Condition.
• For Successful Treatment, It Is Imperative That This Underlying Cause Is Being
Identified And Addressed.
The process of plque formation cn b divided into 3 parts
Goldstd scaling –rp but clinical outcomes not desirable in severe conditions recolonization and recurrence more common (onditions wer SRP cannot offr maximum benefits --
So adjunctive tt are necessary
Authors like bonito etal 2005 confirmed that tetracycline , minocycline most effective in terms of PD reduction & CAL gain locally
Under systemic antibiotics amox –metro combination beneficial otcomes 6 months after FMD. Also beneficaial are tetracyclines and metronidazole haffajee, 2003, hererra 2002, cionca 2009
But complications should be considered before administering Antibiotics systemically
Long wavelength visible light is used to activate photosensitizing agents that produce reactive oxygen species which then reacts with DN, lipids & protiens leading to cell death