Corticosteroids

CORTICOSTEROIDS Prof. Dr. Shah Murad HOD, Pharmacology LM&DC, Lahore

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Physiological control of steroids secretion

Adrenal Steroids ,[object Object],[object Object]

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Short Acting (12 hrs) ,[object Object],[object Object]

Intermediate Acting (12-36 hrs) ,[object Object],[object Object],[object Object],[object Object]

Long Acting (>48 hrs) ,[object Object],[object Object],[object Object]

Pharmacokinetics ,[object Object],[object Object],[object Object],[object Object]

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Glucocorticoid Products (Esters and dose forms) ,[object Object]

ORAL ROUTE ,[object Object],[object Object],[object Object]

IM, Subcutanous, Intralesional ,[object Object],[object Object]

Intravenous ,[object Object],[object Object]

Pharmacodynamics ,[object Object],[object Object],[object Object],[object Object],[object Object]

inflammation ,[object Object],[object Object],[object Object],[object Object]

Discontinuation of glucocorticoids ,[object Object],[object Object],[object Object]

Inhibit immunologic responses ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Reducing dose rates ,[object Object],[object Object]

Alternate day therapy (Anti-inflammatory OR Anti-immunologic) ,[object Object]

How? ,[object Object],[object Object]

Which drugs? ,[object Object],[object Object],[object Object]

Why? ,[object Object],[object Object]

IV use of Glucocorticoids ,[object Object],[object Object],[object Object]

Mineralocorticoids ,[object Object],[object Object],[object Object],[object Object],[object Object]

Aldosterone and Mineralocorticoid Receptors ,[object Object]

Physiologic Effects of Mineralocorticoids ,[object Object],[object Object]

Control of Aldosterone Secretion ,[object Object]

The two most significant regulators of aldosterone secretion are: ,[object Object],[object Object]

Disease States ,[object Object]

Mechanism of action ,[object Object],[object Object]

The androgenic effects of AAS ,[object Object]

Body composition and strength improvements ,[object Object]

Psychiatric effects ,[object Object]

Corticosteroids

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Corticosteroids