This document discusses various methods of classifying crude drugs, including:
1. Morphological classification, which groups drugs based on the plant part used, such as leaves, roots, or stems.
2. Pharmacological classification, which arranges drugs according to their pharmacological actions or therapeutic uses.
3. Chemical classification, which categorizes drugs based on their active chemical constituents, such as alkaloids, glycosides, or tannins.
It provides examples and discusses the merits and demerits of each classification system. The goal is to adopt a method that is simple, easy to use, and avoids confusion, while recognizing each system has its own advantages and limitations.
Medicinal plants have been identified and used throughout human history. Plants make many chemical compounds that are for biological functions, including defence against insects, fungi and herbivorous mammals. At least 12,000 such compounds have been isolated so far; a number estimated to be less than 10% of the total.Chemical compounds in plants mediate their effect on the human body through processes identical to those already well understood for the chemical compounds in conventional drugs; thus herbal medicines do not differ greatly from conventional drugs in terms of how they work. it is important to know various factors that affects medicinal plant cultivation.
Crude drugs are plant, animal or their parts which after collection are subjected only to drying or making them into transverse/ longitudinal slices pieces or peeling them in some cases. They exist in natural form.
Crude drugs may be derived from various natural sources like Plants, Animals, Minerals, Marine and Micro-organisms etc
Medicinal plants have been identified and used throughout human history. Plants make many chemical compounds that are for biological functions, including defence against insects, fungi and herbivorous mammals. At least 12,000 such compounds have been isolated so far; a number estimated to be less than 10% of the total.Chemical compounds in plants mediate their effect on the human body through processes identical to those already well understood for the chemical compounds in conventional drugs; thus herbal medicines do not differ greatly from conventional drugs in terms of how they work. it is important to know various factors that affects medicinal plant cultivation.
Crude drugs are plant, animal or their parts which after collection are subjected only to drying or making them into transverse/ longitudinal slices pieces or peeling them in some cases. They exist in natural form.
Crude drugs may be derived from various natural sources like Plants, Animals, Minerals, Marine and Micro-organisms etc
Adulteration is a practice of substituting original crude drug partially or whole with other similar looking substances but the latter is either free from or inferior in chemical and therapeutic properties. Adulteration in simple words is the debasement of an article. OR Adulteration is broadly defined as admixture or substitution of original or genuine article/ drug with inferior, defective or otherwise useless or harmful substances.
ADULTRANT : The adulterant must be some material which in both cheap and available in fairly large amounts.
Cultivation,Collection, Processing and Storage of crude drugsJegan Nadar
Thus PPT covers Cultivation,Collection, Processing and Storage of crude drugs. This ppt includes different methods of propagation, pest and pest control management, growth regulators, polyploidy, hybridization, collection of crude drugs and storage of crude drugs.
PHARMACOGNOSY & Phytochemistry-I (BP405T)Unit-IIPart-2.FACTORS AFFECTING CULTIVATION
1. Altitude
2.Temperature
3. Rainfall
4. Day Length and Day Light
5. Soil
6. Soil Fertility
7. Fertilizers and Manures
a) Chemical fertilizers
(b) Manures
(c) Biofertilizers
8. Pests and Pests Control
a. Microbes
b) Insects
C) Non insect pests
d) Weeds
9. Other Factors that Affect the Cultivated Plants
a. Air Pollution
b. Herbicide
Cultivation and collection of drugs of natural originZuli Shingala
cultivation and collection of medicinal plants, processing, storage, etc. with various factors that affects cultivation and collection of medicinal plants
Evaluation of drug means confirmation of its identity and determination of its quality and purity and detection of nature of adulteration.Evaluation of herbal drug is an important tool in the formulation of high quality herbal products. Quality of herb is
depends upon on many factors like cultivation, collection, drying, storage, processing for market etc. Now a day’s
substitution and adulteration of herb is very common due to scarcity of drug and its high price prevailing in the
market. Owing to medicinal properties attributed to an herb, it is necessary to maintain its quality and purity in the
commercial market. A present overview covering various tool like morphological, microscopical, physical, chemical
and biological employed for evaluation of herbal drugs.
Classification of Crude Drugs. HARMACognosy & Phytochemistry-I (BP405T)Unit-I...Ms. Pooja Bhandare
Classification of Crude Drugs.PHARMACognosy & Phytochemistry-I (BP405T)Unit-I Part-2.
A method of classification should be:
a) simple,
b) easy to use, and
c) free from confusion and ambiguities.
TYPES OF CLASSIFICATION.
1.Alphabetical classification
2.Taxonomical classification
3.Morphological classification
4.Pharmacological classification
5.Chemical classification
6.Chemotaxonomical classification
7. Serotaxanomical Classification
Adulteration is a practice of substituting original crude drug partially or whole with other similar looking substances but the latter is either free from or inferior in chemical and therapeutic properties. Adulteration in simple words is the debasement of an article. OR Adulteration is broadly defined as admixture or substitution of original or genuine article/ drug with inferior, defective or otherwise useless or harmful substances.
ADULTRANT : The adulterant must be some material which in both cheap and available in fairly large amounts.
Cultivation,Collection, Processing and Storage of crude drugsJegan Nadar
Thus PPT covers Cultivation,Collection, Processing and Storage of crude drugs. This ppt includes different methods of propagation, pest and pest control management, growth regulators, polyploidy, hybridization, collection of crude drugs and storage of crude drugs.
PHARMACOGNOSY & Phytochemistry-I (BP405T)Unit-IIPart-2.FACTORS AFFECTING CULTIVATION
1. Altitude
2.Temperature
3. Rainfall
4. Day Length and Day Light
5. Soil
6. Soil Fertility
7. Fertilizers and Manures
a) Chemical fertilizers
(b) Manures
(c) Biofertilizers
8. Pests and Pests Control
a. Microbes
b) Insects
C) Non insect pests
d) Weeds
9. Other Factors that Affect the Cultivated Plants
a. Air Pollution
b. Herbicide
Cultivation and collection of drugs of natural originZuli Shingala
cultivation and collection of medicinal plants, processing, storage, etc. with various factors that affects cultivation and collection of medicinal plants
Evaluation of drug means confirmation of its identity and determination of its quality and purity and detection of nature of adulteration.Evaluation of herbal drug is an important tool in the formulation of high quality herbal products. Quality of herb is
depends upon on many factors like cultivation, collection, drying, storage, processing for market etc. Now a day’s
substitution and adulteration of herb is very common due to scarcity of drug and its high price prevailing in the
market. Owing to medicinal properties attributed to an herb, it is necessary to maintain its quality and purity in the
commercial market. A present overview covering various tool like morphological, microscopical, physical, chemical
and biological employed for evaluation of herbal drugs.
Classification of Crude Drugs. HARMACognosy & Phytochemistry-I (BP405T)Unit-I...Ms. Pooja Bhandare
Classification of Crude Drugs.PHARMACognosy & Phytochemistry-I (BP405T)Unit-I Part-2.
A method of classification should be:
a) simple,
b) easy to use, and
c) free from confusion and ambiguities.
TYPES OF CLASSIFICATION.
1.Alphabetical classification
2.Taxonomical classification
3.Morphological classification
4.Pharmacological classification
5.Chemical classification
6.Chemotaxonomical classification
7. Serotaxanomical Classification
Classification of Crude Drugs, topic from Pharmacognosy subject. These slides gives basic information about how the crude drugs are generally classified, its different forms and types.
The all the content in this profile is completed by the teachers, students as well as other health care peoples.
thank you, all the respected peoples, for giving the information to complete this presentation.
this information is free to use by anyone.
Classification of Crude Drugs by Mr. Qureshi Alfaiz shaikh iqbal.pptxShaikhAlfaiz
Classification of Crude Drugs in which variuos types of classification like morphological, Taxonomical, Serotaxonomical etc by Mr. Qureshi Alfaiz shaikh iqbal Assit. Professor, Department of Pharmacognosy at SMT. Sharadchandrika Suresh Patil College of Pharmacy Chopda-425107
classification of drugs from natural origin
alphabetical, morphological, pharmacological, chemical, taxonomical, chemotaxonomical, serotaxonomical classifications are included in the presentation
The Umbelliferae family is named after the shape of its flowers, which are called umbels.
The umbels are unique in their floral uniformity
These distinctive umbrella shaped blooms are attractive in arrangements and loved by numerous beneficial insects.
They pollinate freely which allow it to increase its natural distribution.
Seed dispersal occurs through wind.
CONIUM
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FENNEL
CORRIANDER
ASAFOETIDA
Tissues definition and classification, function & location of of epithelium tissues, connective tissues, muscular tissues, nervous tissue etc.. it is usefull for the diploma in pharmacy students , bachelor of pharmacy students and doctor of pharmacy students
it involves the general principles of poisoning treatment and various basic principles of management of poisoning IT IS USEFULL FOR THE IV.PHARM D STUDENTS AND MEDICAL STUDENTS
general principles of poisoning ang introduction to clinical toxicology it is useful for the doctor of pharmacy students and pharmacology students master of pharmacy students and bachelor of pharmacy students
structure and functions of heart and different stages of cardiac cycle, Electrocardiograph and its significance it is useful for the diploma in pharmacy students and bachelor off pharmacy and Doctor of Pharmacy Students an also Basic physiology students
IT IS USEFUL FOR THE STUDENTS OF DIPLAMO IN PHARMCY AND BACHELOR OF PHARMACY SRUDENTS IT IS ALSO USEFULL FOR THE SECOND YEAR DOCTOR OF PHARMCSY STUDENTS
IT SI USEFULL FOR THE STUDENTS OF DIPLOMA IN PHARMCY AND BACHELOR OF PHARMACY AND DOCTOR OF PHARMACY STUDENTS
IT IS VERY USEFULL FORTHE II.B.PHARM SECOND SEMESTER STRUDENTSSOURCE OF CRUDE DRUGS
IT IS USEFULL FOR THE PHARMCY STUDENTS FOR BACHELOR OF PHARMCY AND DOCTOR OF PHARMCY STUDENTS FOR B.PHARM SECOND YEAR STUDENTS AND SECOND YEAR DOCTOR OF PHARMACY STUDENTS
it is usefull for the students of diploma in pharmacy, II.B.PHARM FIRST SEMESTER AND DOCTOR OF PHARMACY SECOND YEAR STUDENTS AND ALSO BASIC KNOWLEDGE FOR IDENTIFICATION OF CRUDE DRUGS
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The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
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1. CLASSIFICATION OF CRUDE
DRUGS
The most important natural sources of drugs are higher plant, microbes and animals and marine
organisms. Some useful products are obtained from minerals that are both organic and
inorganic in nature. In order to pursue (or to follow) the study of the individual drugs, one must
adopt some particular sequence of arrangement, and this is referred to a system of
classification of drugs.
A method of classification should be:
a) simple,
b) easy to use, and
c) free from confusion and ambiguities.
2.
3. Because of their wide distribution, each arrangement of
classification has its own merits and demerits, but for the
purpose of study the drugs are classified in the following
different ways:
4. classified in the following different ways:
1. Alphabetical classification
2. Taxonomical classification
3. Morphological classification
4. Pharmacological classification
5. Chemical classification
6. Chemotaxonomical classification
7. Serotaxonomical classification
5. Alphabetical Classification
Alphabetical classification is the simplest way of classifica-tion of any disconnected
items. Crude drugs are arranged in alphabetical order of their Latin and English
names (common names) or sometimes local language names (ver-nacular names).
Some of the pharmacopoeias, dictionaries and reference books which classify crude
drugs according to this system are as follows:
6. Reference books
1. Indian Pharmacopoeia
2. British Pharmacopoeia
3. British Herbal Pharmacopoeia
4. United States Pharmacopoeia and
National Formu-lary
5. British Pharmaceutical Codex
6. European Pharmacopoeia
7. In European Pharmacopoeia these are
arranged according to their names in Latin
where in United States Pharmaco-poeia
(U.S.P.) and British Pharmaceutical Codex
(B.P.C.), these are arranged in English.
8. Merits
Merits
· It is easy and quick to use.
· There is no repetition of entries and is devoid of con-fusion.
· In this system location, tracing and addition of drug entries is easy.
Demerits
There is no relationship between previous and successive drug entries.
Examples: Acacia, Benzoin, Cinchona, Dill, Ergot, Fennel, Gentian,
Hyoscyamus, Ipecacuanha, Jalap, Kurchi, Liquorice, Mints, Nux vomica,
Opium, Podophyllum, Quassia, Rauwolfia, Senna, Vasaka, Wool fat,
Yellow bees wax, Zeodary.
9. Demerits
There is no relationship between previous and
successive drug entries.
Examples: Acacia, Benzoin, Cinchona, Dill,
Ergot, Fennel, Gentian, Hyoscyamus,
Ipecacuanha, Jalap, Kurchi, Liquorice, Mints, Nux
vomica, Opium, Podophyllum, Quassia,
Rauwolfia, Senna, Vasaka, Wool fat, Yellow bees
wax, Zeodary.
10. Taxonomical Classification
All the plants possess different characters of
morphologi-cal, microscopical, chemical,
embryological, serological and genetics. In this
classification the crude drugs are classified
according to kingdom, subkingdom, division,
class, order, family, genus and species as follows.
13. Superorder
A group of related plant families, classified in
the order in which they are thought to have
developed their dif-ferences from a common
ancestor. There are six superorders in the
Dicotyledonae (Magnoliidae, Hamamelidae,
Caryophyl-lidae, Dilleniidae, Rosidae, Asteridae),
and four superorders in the Monocotyledonae
(Alismatidae, Commelinidae, Arecidae,
and Liliidae). The names of the superorders end
in –idae.
14. Order
Each superorder is further divided into several
orders.
The names of the orders end in –ales.
15. Family
Each order is divided into families. These are plants with many
botanical features in common, and are the highest classification
normally used. At this level, the similarity between plants is often
easily recognizable by the layman. Modern botanical
classification assigns a type plant to each family, which has the
particular characteristics that separate this group of plants from
others, and names the family after this plant.
The number of plant families varies according to the botanist
whose classification you follow. Some botanists recognize only
150 or so families, preferring to classify other similar plants as
subfamilies, while others recognize nearly 500 plant families. A
widely accepted system is that devised by Cronquist in 1968,
which is only slightly revised today. The names of the families
end in –aceae.
16. Subfamily
The family may be further divided into a
number of subfamilies, which group together
plants within the family that have some
significant botanical differences. The names
of the subfamilies end in –oideae.
17. Tribe
A further division of plants within a family,
based on smaller botanical differences, bin
still usually comprising many different plants.
The names of the tribes end in –eae.
18. Subtribe
A further division based on even smaller
botanical differences, often only recognizable
to botanists. The names of the subtribes end
in –inae.
19. Genus
This is the part of the plant name that is most
famil-iar; the normal name that you give a
plant—Papaver (Poppy), Aquilegia
(Columbine), and so on. The plants in a
genus are often easily recognizable as
belonging to the same group.
20. Species
This is the level that defines an individual plant. Often,
the name will describe some aspect of the plant— the
colour of the flowers, size or shape of the leaves, or it
may be named after the place where it was found.
Together, the genus and species name refer to only
one plant, and they are used to identify that particular
plant. Sometimes, the species is further divided into
subspecies that contain plants not quite so distinct that
they are classified as variet-ies. The name, of the
species should be written after the genus name, in
small letters, with no capital letter.
21. Variety
A variety is a plant that is only slightly
different from the species plant, but the
differences are not so insig-nificant as the
differences in a form. The Latin is varietas,
which is usually abbreviated to var. The name
follows the genus and species name, with var.
before the individual variety name.
22. Form
A form is a plant within a species that has
minor botanical differences, such as the
colour of flower or shape of the leaves. The
name follows the genus and species name,
with form (or f.) before the individual variety
name.
23. Cultivar
A cultivar is a cultivated variety—a particular plant
that has arisen either naturally or through
deliberate hybridization, and can be reproduced
(vegetatively or by seed) to produce more of the
same plant.
The name follows the genus and species name. It
is written in the language of the person who
described it, and should not be translated. It is
either written in single quotation marks or has cv.
written in front of the name.
24.
25.
26. Merits &Demerits
Merits
Taxonomical classification is helpful for studying
evolution-ary developments.
Demerits
This system also does not correlate in between
the chemical constituents and biological activity of
the drugs.
27. Morphological Classification
In this system, the drugs are arranged according to the
morphological or external characters of the plant parts or
animal parts, i.e. which part of the plant is used as a
drug, e.g. leaves, roots, stem, etc.
28. unorga-nized drugs
The drugs which are pre-pared from plants by
some intermediate physical processes such
as incision, drying or extraction with a solvent
and not containing any cellular plant tissues
are called unorga-nized drugs. Aloe juice,
opium latex, agar, gambir, gelatin, tragacanth,
benzoin, honey, beeswax, lemon grass oil,
etc., are examples of unorganized drugs.
29. Organized drugs
The drugs obtained from the direct parts of
the plants and containing cellular tissues are
called as organized drugs, e.g. rhizomes,
barks, leaves, fruits, entire plants, hairs and
fibres.
37. Merits
Morphological classification is more helpful to
identify and detect adulteration.
This system of classification is more convenient
for practical study especially when the chemical
nature of the drug is not clearly understood.
38. Demerits
The main drawback of morphological
classification is that there is no corelation of
chemical constituents with the therapeutic
actions.
Repetition of drugs or plants occurs.
39. Pharmacological Classification
Grouping of drug according to their
pharmacological action or of most important
constituent or their therapeutic use is termed
as pharmacological or therapeutic
classification of drug.
40. Pharmacological Classification
This classification is more relevant and is
mostly a followed method.
Drugs like digitalis, squill and strophan-thus
having cardiotonic action are grouped
irrespective of their parts used or phylogenetic
relationship or the nature of phytoconstituents
they contain
43. Merits
This system of classification can be used for suggesting
substitutes of drugs, if they are not available at a
particular place or point of time.
The special advantage is that if even chemical
constituents of the crude drugs are not known they can
be classified properly on the basis of therapeutic or
pharmacological uses.
44. Demerits
Drugs having different action on the body get
classified separately in more than one group
that causes ambiguity and confusion.
Cinchona is antimalarial drug because of
presence of quinine but can be put under the
group of drug affecting heart because of
antiarrhythmic action of quinidine.
45. Demerits
Regardless of morphology, taxonomical status or
chemicalnature, the drugs are grouped together,
provided they exhibit similar pharmacological
uses.
Eg: Senna, Castor oil, Jalap, Colocynth are
grouped together as purgatives/laxatives because of
their common pharmacological action.
Same drug having different actions, may be
included in more than one category.
46. Chemical Classification
Depending upon the active constituents, the crude
drugs are classified. The plants contain various
constituents in them like alkaloids, glycosides,
tannins, carbohydrates, saponins, etc. Irrespective
of the morphological or taxonomical char-acters,
the drugs with similar chemical constituents are
grouped into the same group. The examples are
shown in this table.
47. Chemical Classification
Depending upon the active constituents, the crude
drugs are classified. The plants contain various
constituents in them like alkaloids, glycosides,
tannins, carbohydrates, saponins, etc. Irrespective
of the morphological or taxonomical char-acters,
the drugs with similar chemical constituents are
grouped into the same group. The examples are
shown in this table.
49. Merits
It is a popular approach for phytochemical
studies.
50. Demerits
Ambiguities arise when particular drugs
possess a number of compounds belonging to
different groups of compounds.
51. Chemotaxonomical Classification
This system of classification relies on the chemical similarity of a taxon,
i.e. it is based on the existence of relationship between constituents in
various plants.
There are certain types of chemical constituents that characterize
certain classes of plants.
This gives birth to entirely a new concept of chemotaxonomy that
utilizes chemical facts/characters for understanding the taxonomical
status, relationships and the evolution of the plants.
52. Chemotaxonomical Classification
For example, tropane alkaloids generally occur among the
members of Solanaceae, thereby, serving as a chemot-
axonomic marker.
Similarly, other secondary plant metabo-lites can serve as
the basis of classification of crude drugs. The berberine
alkaloid in Berberis and Argemone, Rutin in Rutaceae
members, Ranunculaceae alkaloids among its members,
etc., are other examples.
53.
54.
55. Serotaxonomical Classification
The serotaxonomy can be explained as the study about the
application or the utility of serology in solving the taxo nomical
problems.
Serology can be defined as the study of the antigen–antibody
reaction.
Antigens are those sub-stances which can stimulate the formation of
the antibody.
Antibodies are highly specific protein molecule produced by plasma
cells in the immune system. Protein are carri-ers of the taxonomical
information and commonly used as antigen in serotaxonomy.
56.
57.
58.
59.
60. Serotaxonomical Classification
It expresses the similarities and the
dissimilarities among different taxa, and these
data are helpful in taxonomy. It deter-mines
the degree of similarity between species,
genera, family, etc., by comparing the reaction
with antigens from various plant taxa with
antibodies present against a given taxon.
61.
62.
63.
64.
65.
66.
67.
68. Serotaxonomical Classification
Serology helps in comparing
nonmorphological charac-teristics, which
helps in the taxonomical data. This tech-nique
also helps in the comparison of single
proteins from different plant taxa.