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Classification of Crude Drugs
Presented by: Asst. Prof. Alfaiz Qureshi
(M. Pharm Pharmacognosy)
Dept. of Pharmacognosy
MGSM’s Smt. S. S. Patil College of Pharmacy Chopda, Dist. Jalgaon
Classification of Crude Drugs
Introduction
Alphabetical
Morphological
Taxonomical
Chemical
Pharmacological
Chemo and Serotaxonomical
Introduction
Classification of Crude Drugs
Crude drug:
Crude drugs are plant, animal or their parts which after
collection are subjected only to drying or making them into
transverse/ longitudinal slices pieces or peeling them in some
cases. They exist in natural form. Crude drugs may be
derived from various natural sources like plants, animals,
minerals and micro- organisms etc.
• Because of their wide distribution the arrangement of classification
in a definite sequence is necessary to understand easily. Although
each system of classification has its own merits and demerits, but
for the purpose of study the drugs are classified in the following
different ways:
• Alphabetical classification
• Morphological classification
• Taxonomical classification
• Pharmacological classification
• Chemical classification
• Chemo-taxonomical classification
Alphabetical Classification
The crude drugs are arranged according to the
alphabetical order/form of their Latin and English names.
Some of the Pharmacopoeias and reference books which
classify crude drugs according to this system are as follows.
1)Indian Pharmacopoeia (IP) 1955 (Latin)
2)Indian Pharmacopoeia (IP) 1966 (English)
3)British Pharmacopoeia (BP) (English)
4)British Pharmacopoeia Codex (BPC) (English)
5)United States of Pharmacopoeia (USP) (English)
6)European Pharmacopoeia (Latin)
Advantages:
• It is simple method, in this system location, Finding, tracing and addition of the drug is easy,
• No technical person is required for handling the system.
Disadvantages:
• Scientific nature of the drug cannot be identified by this method
• whether they are organized or unorganized drug.
• This system does not help in distinguishing the drugs Source- whether its from plant, animal and
mineral source.
• Examples:
• Acacia, Agar, Benzoin, Cinchona, Digitalis, Ephedra, Fennel, Ginger, Hyoscyamus, Isapgol,
Jalap, Kino, Linseed, Mustard, Nutmeg, Opium, Quassia, Rauwolfia, Senna, Vasaka, Wool fat,
Yellow bees wax, Zeodary
Morphological Classification
Here the crude drugs are arranged (Grouped) according to the part of
the plant or animal represented into organized (Cellular) drugs and
unorganized ( Acellular ) drugs.
Organized (Cellular): They are the direct parts of the plant and are
divided into leaves, barks wood, root, rhizome, seed, fruit, flower,
stem, hair and fibers.
Unorganized (Acellular): They are the products of plant, animal
and mineral source and they are divided into dried latex, dried juice,
dried extracts, gums, resins, fixed oils and fats, waxes, volatile oil,
animal products, minerals (Solids, liquids, semi solids etc.).
Organized Drug
Plant Parts Drugs
Leave Datura, Senna, Vasaka, Digitalis
Bark Cinchona, Cinnamon, Kurchi
Wood Quassia, Sandalwood, Red sander
Roots Rauwolfia, Liquorice, Ipecac
Rhizomes Ginger, Podophyllum, Turmeric
Seeds Nux Vomica, Linseed, Isapgol
Flower Clove, Saffron, Fennel, coriander
Stem Ephedra
Hair and Fibers Cotton, Hemp, Jute
Unorganized
Plant, Animal, Mineral Drugs
Dried Latex Opium, Papain
Dried Juice Aloe, Kino
Dried Extract Agar, Catechu, Pectin
Gums Acacia, Tragacanth, Sterculia
Resins Benzoin, Colophony, Asafoetida
Fixed Oil and Fats Castor, Chaulmogra, Cotton seed
Waxes Beesawax, Spermaceti
Advantages:
• This system of classification is more convenient for practical study especially when the
chemical nature of the drug is not clearly understood.
• This type of classification is very useful in identifying the adulterants used.
• Disadvantages:
• It does not give an idea about biological source, chemical constituents and uses.
• When different parts of the plant contain different chemical constituents, it is difficult to
classify them.
Chemical Classification
Here, the crude drugs are divided into different
groups according to the chemical nature of their
most important constituent present in the drug to
which the pharmacological/therapeutic activity of
drug is attributed.
Chemical Classification
Chemical Constituents Drug
Alkaloids Datura, Vasaka, Vinca, Lobelia
Glycosides Cascara, Senna, Digitalis
Tannins Catechu, Myrobalan, Ashoka
Volatile Oil Clove, Eucalyptus, Cinnamon
Lipids Castor Oil, Beeswax, Arachis oil,
Carbohydrate and derived Product Acacia, Agar, Honey, Linseed,
Tragacanth, Starch
Chemical Classification
Advantages:
• Chemical constituents are known
• Medicinal uses are known
Disadvantages :
• Drugs of different origin are grouped under similar chemical titles.
• This type of classification makes no proper placement of drugs containing two different
types of chemicals.
• Eg: Certain drugs are found to contain alkaloids and glycosides (Cinchona), Fixed oil and
volatile oil (Nutmeg) of equal importance together and hence it is difficult to categorize
them properly
Taxonomical Classification
• In this system the drug are arranged according
to taxonomical studies. The drugs are arranged
according to their phylum, order, family, genus
and species. It is purely a type of botanical
classification or biological classification and
restricted mainly to crude drugs from plant
source.
Taxonomical Classification
Phylum Order Family Drugs
Angiosperms
(Monocotyledons)
Liliflorae Liliacae Colchicum, Asparagus,
Dioscorea, Vanilla
Microspermae Dioscoriaceae
Angiosperms
(Dicotyledons)
Papaverales Papaveraceae Opium
Rosales Rosales Almond, Rose Oil
Leguminosae Glycyrrhiza, Senna
Rutales Rutaceae Bael, Lemon, Orange
Umbelliflorae Umbelliferae Coriander, Caraway, Fennel
Gentianales Loganiaceae Nux Vomica
Taxonomical Classification
Advantages:
• Easy for the classification of crude drugs
Disadvantages:
• The system is criticized for its failure to recognize the organised / unorganised nature of
crude drugs in their morphological studies.
• The system fails to face into an account chemical nature of active constituent and
therapeutic significance of crude drugs.
• The drugs obtained from plants having alternate leaves, flowers, seeds, capsules
(Hyocyamus, Datura, Bellodonna, Stromonium) are considered with other members of
solanaceae.
Pharmacological Classification
•Here, the crude drugs are grouped according to
pharmacological action (Therapeutic action) of
their chief active constituent (most important)
or therapeutic uses.
Pharmacological Classification
Pharmacological Effect Drugs
Bitter Quassia, Cinchona, Gentiana
Carminatives Dill, Clove, Fennel, Coriander
Emetics Ipecac
Antiamoebics Kurchi, Ipecac
Bulk Laxatives Agar, Isapgol
Purgative Senna, Castor Oil
Expectorants Liquorice,Vasaka, Ipecac
Anti-Tussive Opium
Bronchodilators Ephedra, Tea
Cardio-Tonics Digitalis, Squill, Stropanthus
Cardiac Depressants Cinchona, Veratrum
Anti-Hypertenssives Rauwolfia
Pharmacological Classification
Advantages:
• The special advantage is that if even chemical constituents of the crude drugs are not
known they can be classified properly on the basis of therapeutic or pharmacological
uses.
Disadvantages:
• Regardless of morphology, taxonomical status or chemical nature, the drugs are grouped
together, provided they exhibit similar pharmacological uses.
• Eg: Senna, Castor oil, Jalap, Colocynth are grouped together as purgatives/laxatives
because of their common pharmacological action.
Chemo-Taxonomical Classification
In this system of classification, the equal importance is
given for taxonomical status and chemical constituents.
There are certain types of chemical constituents which are
characteristics of certain classes of plants.
•Eg: Tropane alkaloids generally occur in most of the
members of Solanaceae
•Eg: Volatile oils occur in the members of Umbelliferae
and Rutaceae.
Serotaxonomical Classification
• serotaxonomy can be explained as the study about the application or the
utility of serology in solving the taxonomical problems.
• Serology can be defined as the study of the antigen–antibody reaction.
• Antigens are those substances which can stimulate the formation of the
antibody.
• Antibodies are highly specific protein molecule produced by plasma cells in
the immune system.
• Protein are carriers of the taxonomical information and commonly used as
antigen in serotaxonomy.
• When foreign cells or particles (antigens) are introduced into an organism,
antibodies are produced in the blood (antiserum).
Serotaxonomical Classification
• The classification is based on similar plants by means of differences in the
proteins they contain.
• It expresses the similarities and the dissimilarities among different taxa, and
these data are helpful in taxonomy.
• It determines the degree of similarity between species, genera, family, etc.,
by comparing the reaction with antigens from various plant taxa with
antibodies present against a given taxon.
• Serology helps in comparing nonmorphological characteristics, which helps
in the taxonomical data.
• This technique also helps in the comparison of single proteins from different
plants.
Thank You…

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Classification of Crude Drugs by Mr. Qureshi Alfaiz shaikh iqbal.pptx

  • 1. Classification of Crude Drugs Presented by: Asst. Prof. Alfaiz Qureshi (M. Pharm Pharmacognosy) Dept. of Pharmacognosy MGSM’s Smt. S. S. Patil College of Pharmacy Chopda, Dist. Jalgaon
  • 2. Classification of Crude Drugs Introduction Alphabetical Morphological Taxonomical Chemical Pharmacological Chemo and Serotaxonomical
  • 3. Introduction Classification of Crude Drugs Crude drug: Crude drugs are plant, animal or their parts which after collection are subjected only to drying or making them into transverse/ longitudinal slices pieces or peeling them in some cases. They exist in natural form. Crude drugs may be derived from various natural sources like plants, animals, minerals and micro- organisms etc.
  • 4. • Because of their wide distribution the arrangement of classification in a definite sequence is necessary to understand easily. Although each system of classification has its own merits and demerits, but for the purpose of study the drugs are classified in the following different ways: • Alphabetical classification • Morphological classification • Taxonomical classification • Pharmacological classification • Chemical classification • Chemo-taxonomical classification
  • 5. Alphabetical Classification The crude drugs are arranged according to the alphabetical order/form of their Latin and English names. Some of the Pharmacopoeias and reference books which classify crude drugs according to this system are as follows.
  • 6. 1)Indian Pharmacopoeia (IP) 1955 (Latin) 2)Indian Pharmacopoeia (IP) 1966 (English) 3)British Pharmacopoeia (BP) (English) 4)British Pharmacopoeia Codex (BPC) (English) 5)United States of Pharmacopoeia (USP) (English) 6)European Pharmacopoeia (Latin)
  • 7. Advantages: • It is simple method, in this system location, Finding, tracing and addition of the drug is easy, • No technical person is required for handling the system. Disadvantages: • Scientific nature of the drug cannot be identified by this method • whether they are organized or unorganized drug. • This system does not help in distinguishing the drugs Source- whether its from plant, animal and mineral source. • Examples: • Acacia, Agar, Benzoin, Cinchona, Digitalis, Ephedra, Fennel, Ginger, Hyoscyamus, Isapgol, Jalap, Kino, Linseed, Mustard, Nutmeg, Opium, Quassia, Rauwolfia, Senna, Vasaka, Wool fat, Yellow bees wax, Zeodary
  • 8. Morphological Classification Here the crude drugs are arranged (Grouped) according to the part of the plant or animal represented into organized (Cellular) drugs and unorganized ( Acellular ) drugs. Organized (Cellular): They are the direct parts of the plant and are divided into leaves, barks wood, root, rhizome, seed, fruit, flower, stem, hair and fibers. Unorganized (Acellular): They are the products of plant, animal and mineral source and they are divided into dried latex, dried juice, dried extracts, gums, resins, fixed oils and fats, waxes, volatile oil, animal products, minerals (Solids, liquids, semi solids etc.).
  • 9. Organized Drug Plant Parts Drugs Leave Datura, Senna, Vasaka, Digitalis Bark Cinchona, Cinnamon, Kurchi Wood Quassia, Sandalwood, Red sander Roots Rauwolfia, Liquorice, Ipecac Rhizomes Ginger, Podophyllum, Turmeric Seeds Nux Vomica, Linseed, Isapgol Flower Clove, Saffron, Fennel, coriander Stem Ephedra Hair and Fibers Cotton, Hemp, Jute
  • 10. Unorganized Plant, Animal, Mineral Drugs Dried Latex Opium, Papain Dried Juice Aloe, Kino Dried Extract Agar, Catechu, Pectin Gums Acacia, Tragacanth, Sterculia Resins Benzoin, Colophony, Asafoetida Fixed Oil and Fats Castor, Chaulmogra, Cotton seed Waxes Beesawax, Spermaceti
  • 11. Advantages: • This system of classification is more convenient for practical study especially when the chemical nature of the drug is not clearly understood. • This type of classification is very useful in identifying the adulterants used. • Disadvantages: • It does not give an idea about biological source, chemical constituents and uses. • When different parts of the plant contain different chemical constituents, it is difficult to classify them.
  • 12. Chemical Classification Here, the crude drugs are divided into different groups according to the chemical nature of their most important constituent present in the drug to which the pharmacological/therapeutic activity of drug is attributed.
  • 13. Chemical Classification Chemical Constituents Drug Alkaloids Datura, Vasaka, Vinca, Lobelia Glycosides Cascara, Senna, Digitalis Tannins Catechu, Myrobalan, Ashoka Volatile Oil Clove, Eucalyptus, Cinnamon Lipids Castor Oil, Beeswax, Arachis oil, Carbohydrate and derived Product Acacia, Agar, Honey, Linseed, Tragacanth, Starch
  • 14. Chemical Classification Advantages: • Chemical constituents are known • Medicinal uses are known Disadvantages : • Drugs of different origin are grouped under similar chemical titles. • This type of classification makes no proper placement of drugs containing two different types of chemicals. • Eg: Certain drugs are found to contain alkaloids and glycosides (Cinchona), Fixed oil and volatile oil (Nutmeg) of equal importance together and hence it is difficult to categorize them properly
  • 15. Taxonomical Classification • In this system the drug are arranged according to taxonomical studies. The drugs are arranged according to their phylum, order, family, genus and species. It is purely a type of botanical classification or biological classification and restricted mainly to crude drugs from plant source.
  • 16. Taxonomical Classification Phylum Order Family Drugs Angiosperms (Monocotyledons) Liliflorae Liliacae Colchicum, Asparagus, Dioscorea, Vanilla Microspermae Dioscoriaceae Angiosperms (Dicotyledons) Papaverales Papaveraceae Opium Rosales Rosales Almond, Rose Oil Leguminosae Glycyrrhiza, Senna Rutales Rutaceae Bael, Lemon, Orange Umbelliflorae Umbelliferae Coriander, Caraway, Fennel Gentianales Loganiaceae Nux Vomica
  • 17. Taxonomical Classification Advantages: • Easy for the classification of crude drugs Disadvantages: • The system is criticized for its failure to recognize the organised / unorganised nature of crude drugs in their morphological studies. • The system fails to face into an account chemical nature of active constituent and therapeutic significance of crude drugs. • The drugs obtained from plants having alternate leaves, flowers, seeds, capsules (Hyocyamus, Datura, Bellodonna, Stromonium) are considered with other members of solanaceae.
  • 18. Pharmacological Classification •Here, the crude drugs are grouped according to pharmacological action (Therapeutic action) of their chief active constituent (most important) or therapeutic uses.
  • 19. Pharmacological Classification Pharmacological Effect Drugs Bitter Quassia, Cinchona, Gentiana Carminatives Dill, Clove, Fennel, Coriander Emetics Ipecac Antiamoebics Kurchi, Ipecac Bulk Laxatives Agar, Isapgol Purgative Senna, Castor Oil Expectorants Liquorice,Vasaka, Ipecac Anti-Tussive Opium Bronchodilators Ephedra, Tea Cardio-Tonics Digitalis, Squill, Stropanthus Cardiac Depressants Cinchona, Veratrum Anti-Hypertenssives Rauwolfia
  • 20. Pharmacological Classification Advantages: • The special advantage is that if even chemical constituents of the crude drugs are not known they can be classified properly on the basis of therapeutic or pharmacological uses. Disadvantages: • Regardless of morphology, taxonomical status or chemical nature, the drugs are grouped together, provided they exhibit similar pharmacological uses. • Eg: Senna, Castor oil, Jalap, Colocynth are grouped together as purgatives/laxatives because of their common pharmacological action.
  • 21. Chemo-Taxonomical Classification In this system of classification, the equal importance is given for taxonomical status and chemical constituents. There are certain types of chemical constituents which are characteristics of certain classes of plants. •Eg: Tropane alkaloids generally occur in most of the members of Solanaceae •Eg: Volatile oils occur in the members of Umbelliferae and Rutaceae.
  • 22. Serotaxonomical Classification • serotaxonomy can be explained as the study about the application or the utility of serology in solving the taxonomical problems. • Serology can be defined as the study of the antigen–antibody reaction. • Antigens are those substances which can stimulate the formation of the antibody. • Antibodies are highly specific protein molecule produced by plasma cells in the immune system. • Protein are carriers of the taxonomical information and commonly used as antigen in serotaxonomy. • When foreign cells or particles (antigens) are introduced into an organism, antibodies are produced in the blood (antiserum).
  • 23. Serotaxonomical Classification • The classification is based on similar plants by means of differences in the proteins they contain. • It expresses the similarities and the dissimilarities among different taxa, and these data are helpful in taxonomy. • It determines the degree of similarity between species, genera, family, etc., by comparing the reaction with antigens from various plant taxa with antibodies present against a given taxon. • Serology helps in comparing nonmorphological characteristics, which helps in the taxonomical data. • This technique also helps in the comparison of single proteins from different plants.