The circulatory system comprises the heart, blood vessels, and blood, and allows blood to circulate nutrients, oxygen, hormones, and other materials to all body tissues, while transporting wastes away. It has two loops - pulmonary circulation which oxygenates blood in the lungs, and systemic circulation which provides oxygenated blood to the rest of the body. The lymphatic system is part of the circulatory system and circulates lymph fluid filtered from tissues back into the blood. Diseases can affect both the cardiovascular and lymphatic systems.