This document summarizes information about the third-generation cephalosporin antibiotic cefixime. It is used to treat ear, sinus, throat, chest and lung, and urinary infections caused by bacteria. Common side effects include diarrhea, nausea, and vomiting. There is no specific antidote for overdose. Cefixime is available as tablets, chewable tablets, dry syrup, and oral suspension under various brand names after its patent expired in 2003.

2.  CLASS- 3rd generation cephalosporin
 Mode of Action-The bactericidal action
of cephalosporin due to the inhibition of
cell wall synthesis.

3.  Use- to treat infections caused by bacteria. -
Ear (otitis media caused by Haemophilus
influenzae, Moraxella catarrhalis,S. pyogenes.)
 sinuses (sinusitis),
 Throat (tonsillitis, pharyngitis caused by S.
pyogenes),
 Chest and lungs (bronchitis, pneumonia
caused by Streptococcus pneumoniae and
Haemophilus influenzae)
 Urinary system and Uncomplicated gonorrhea
caused by Neisseria gonorrhoeae.

4. Adverse drug reactions-
 diarrhea
 dyspepsia
 nausea
 vomiting
 Hypersensitivity reactions like skin
rashes, utricaria, Stevens-Johnson syndrome.
 There is no specific antidote for cefixime
overdosage. Gastric lavage may performed.

5. Drug profile-
 Introduced by Wyeth pharmaceuticals USA.
 Patent expired in 2003
 Generic formulation introduced by Lupin
pharmaceutical and re-launched in USA as
dry syrup under the brand name of SUPRAX.

6. Available formulations-
 Tablet(50mg , 100mg, 200mg)
 Disintegrable Tablet(50mg, 100mg)
 Dry syrup(50mg/30ml)
 Oral suspension(50mg/30ml)

7. Available brand-
 Suprax(Lupin)-Oral suspension, tablet
 Roxim(Eskayef Bangladesh Ltd.)-tablet
 Elfi CV(Elder) –Dry syrup(M.R.P.-
 Trixon CV(Lincoln)- Tablet (M.R.P.-96.40
Rs)
 Zimnic CV - DT

8.  THANK YOU

9. We can't plan life. All we can do is be available for it.