Cefixime is a third-generation cephalosporin antibiotic used to treat infections caused by bacteria in the ears, sinuses, throat, lungs, and urinary tract. It works by inhibiting cell wall synthesis in bacteria. Common side effects include diarrhea, nausea, vomiting, and skin rashes. There is no antidote for an overdose of cefixime, but gastric lavage may be performed. It was introduced by Wyeth pharmaceuticals and is now available generically from companies like Lupin in formulations such as capsules, suspensions, and dry syrups.

2. CLASS- 3rd generation cephalosporin
Mode of Action-The bactericidal
action of cephalosporin due to the
inhibition of cell wall synthesis.

3.  Use- to treat infections caused by bacteria. -Ear (otitis media
caused by Haemophilus influenzae, Moraxella catarrhalis,S.
pyogenes.)
 sinuses (sinusitis),
 Throat (tonsillitis, pharyngitis caused by S. pyogenes),
 Chest and lungs (bronchitis, pneumonia caused
by Streptococcus pneumoniae and Haemophilus influenzae)
 Urinary system and Uncomplicated gonorrhea caused
by Neisseria gonorrhoeae.

4.  Adverse drug reactions-
 Diarrhea,Dyspepsia,Nausea,Vomiting
 Hypersensitivity reactions like skin
rashes, utricaria, Stevens-Johnson syndrome.
 There is no specific antidote for cefixime overdosage.
Gastric lavage may performed.

5.  Drug profile-
 Introduced by Wyeth pharmaceuticals USA.
 Patent expired in 2003
 Generic formulation introduced by Lupin
pharmaceutical and re-launched in USA as dry syrup
under the brand name of SUPRAX.

6.  Available formulations-
Evofix Cap(400mg)
Evofix Susp (100mg/60ml)
Evofix Susp (100mg/30ml)
Evofix Susp DS(200mg/30ml)

7. Any Question????