Bordetella

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Hari, Thoothukudi Govt. Medical College, Thoothukudi

Bordetella pertussis causes whooping cough. It is a gram-negative coccobacillus that forms characteristic colonies on nutrient agar. Its virulence factors include pertussis toxin, filamentous hemagglutinin, and adenylate cyclase. The disease progresses through catarrhal, paroxysmal, and convalescent stages characterized by violent coughing fits followed by a whooping sound. Diagnosis involves culture on Bordet-Gengou or charcoal agar from throat swabs or sputum. Treatment includes erythromycin or other antibiotics, while vaccination with pertussis toxoid can prevent the disease.

BORDETELLA (WHOOPING COUGH) BORDETELLA PERTUSSIS KING OF COUGH!!! G.HARIPRASAD M.Sc.,(Med micro),M.phil., Lecturer in Microbiology Department of Microbiology Thoothukudi Govt. Medical College Thoothukudi

GENERAL FEATURES: ,[object Object],[object Object],[object Object]

VIRULENCE FACTORS: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],PERTUSSIS TOXIN

PATHOGENESIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Entry through inhalation of droplet nuclei.

LABORATORY DIAGNOSIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],CHARCOAL AGAR BORDET-GENGOU MEDIUM

[object Object],[object Object],Erythromycin, Chloramphenicol, Cotrimoxazole Ampicillin . TREATMENT PROPHYLAXIS

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1. BORDETELLA (WHOOPING COUGH) BORDETELLA PERTUSSIS KING OF COUGH!!! G.HARIPRASAD M.Sc.,(Med micro),M.phil., Lecturer in Microbiology Department of Microbiology Thoothukudi Govt. Medical College Thoothukudi

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