The document discusses Mycobacterium tuberculosis, the bacteria that causes tuberculosis. It describes the bacteria's morphology, staining properties, growth characteristics, and pathogenesis. It also covers the transmission and progression of tuberculosis infection, from primary infection to potential extrapulmonary sites. Granuloma formation and caseation necrosis are key aspects of the immune response and typical disease progression.
The PPT is mainly all about Mycobacterium Tuberculosis. Agents causing the disease Tuberculosis, pathogenesis, laboratory diagnosis, treatment and prophylaxis. It was made for both BSc and MSc students.
Cryptococcosis also called as Torulosis is a subacute or chronic fungal infection caused by Cryptococcus neoformans. It leads to compications such as fatal meningoencephalitis. It is an opportunistic infection in HIV-infected patients. The PPT discuss on the morphology of the fungus, pathogenesis, laboratory diagnosis and treatment.
What is Klebsiella? Klebsiella is a Gram-negative rod-shaped bacteria, which belongs to a family of bacteria called the Enterobacteriaceae.
As the channel name suggests, our channel will be a perfect lounge for the malayali medicos..we wil be covering videos which will be like lecture classes related to the subjects biochemistry and microbiology in which we are specialised.. It will be a better learning experience for the students especially for those who are not able to understand and follow the normal classes in college..we assure the students that you will get a basic idea regarding the topic and extra reading can be done from the reference textbooks..
Maneesha M Joseph
MSc MLT (Microbiology)
Assistant Professor
Baby memorial college of allied Health science
Kozhikode
Our Partner Channel
Health & Voyage channel link - https://youtu.be/nzKqRVjlwc0
#Klebsiella
#Medical
#Microbiology
#Biochemistry
#Mallu Medicos Lounge
##MalluMedicosLounge
#MLT
#Channel introduction
#HealthAndVoyage
#New Youtube Channel introduction
#Klebsiella pneumoniae
The PPT is mainly all about Mycobacterium Tuberculosis. Agents causing the disease Tuberculosis, pathogenesis, laboratory diagnosis, treatment and prophylaxis. It was made for both BSc and MSc students.
Cryptococcosis also called as Torulosis is a subacute or chronic fungal infection caused by Cryptococcus neoformans. It leads to compications such as fatal meningoencephalitis. It is an opportunistic infection in HIV-infected patients. The PPT discuss on the morphology of the fungus, pathogenesis, laboratory diagnosis and treatment.
What is Klebsiella? Klebsiella is a Gram-negative rod-shaped bacteria, which belongs to a family of bacteria called the Enterobacteriaceae.
As the channel name suggests, our channel will be a perfect lounge for the malayali medicos..we wil be covering videos which will be like lecture classes related to the subjects biochemistry and microbiology in which we are specialised.. It will be a better learning experience for the students especially for those who are not able to understand and follow the normal classes in college..we assure the students that you will get a basic idea regarding the topic and extra reading can be done from the reference textbooks..
Maneesha M Joseph
MSc MLT (Microbiology)
Assistant Professor
Baby memorial college of allied Health science
Kozhikode
Our Partner Channel
Health & Voyage channel link - https://youtu.be/nzKqRVjlwc0
#Klebsiella
#Medical
#Microbiology
#Biochemistry
#Mallu Medicos Lounge
##MalluMedicosLounge
#MLT
#Channel introduction
#HealthAndVoyage
#New Youtube Channel introduction
#Klebsiella pneumoniae
The genus Shigella exclusively infects human intestine.
Shigella dysenteriae is the causative agent of bacillary dysentery or shigellosis in humans.
It is a diarrheal illness which is characterized by frequent passage of blood stained mucopurulent stools.
The four important species of the genus Shigella are:
Shigella dysenteriae
Shigella flexneri
Shigella sonnei
Shigella boydii.
The genus Shigella exclusively infects human intestine.
Shigella dysenteriae is the causative agent of bacillary dysentery or shigellosis in humans.
It is a diarrheal illness which is characterized by frequent passage of blood stained mucopurulent stools.
The four important species of the genus Shigella are:
Shigella dysenteriae
Shigella flexneri
Shigella sonnei
Shigella boydii.
Spinal Tuberculosis by Dr. Monsif IqbalMonsif Iqbal
This is the case presentation of a middle aged lady who presented with severe backache for the last one month with topic review after the case presentation
En el marco del curso Vacunas antibacterianas, desarrollado por el programa SOS Telemedicina, se presenta la conferencia de la Dra. Sonia Z. Sifontes C. sobre Vacuna BCG.
All you need to know about Tuberculosis (TB)GLRA India
The core activity of GLRA is to cure people affected by leprosy, tuberculosis and to address physical disabilities.
In this presentation, GLRA describes
WHAT WE NEED TO KNOW ABOUT TUBERCULOSIS?
Tuberculosis (TB) is a potentially serious infectious disease that mainly affects the lungs. The bacteria that cause tuberculosis are spread from person to person through tiny droplets released into the air via coughs and sneezes.
Mycobacterium tuberculosis-importance of TB day,classification of Mycobacterium species,Details on Mycobacterium tuberculosis-morphology,culture,resistance,biochemical reactions,antigenic characters,mode of transmission,pathogenesis,complications,lab diagnosis,treatment,DOTS Strategy and prophylaxis
Generating a custom Ruby SDK for your web service or Rails API using Smithyg2nightmarescribd
Have you ever wanted a Ruby client API to communicate with your web service? Smithy is a protocol-agnostic language for defining services and SDKs. Smithy Ruby is an implementation of Smithy that generates a Ruby SDK using a Smithy model. In this talk, we will explore Smithy and Smithy Ruby to learn how to generate custom feature-rich SDKs that can communicate with any web service, such as a Rails JSON API.
Smart TV Buyer Insights Survey 2024 by 91mobiles.pdf91mobiles
91mobiles recently conducted a Smart TV Buyer Insights Survey in which we asked over 3,000 respondents about the TV they own, aspects they look at on a new TV, and their TV buying preferences.
Slack (or Teams) Automation for Bonterra Impact Management (fka Social Soluti...Jeffrey Haguewood
Sidekick Solutions uses Bonterra Impact Management (fka Social Solutions Apricot) and automation solutions to integrate data for business workflows.
We believe integration and automation are essential to user experience and the promise of efficient work through technology. Automation is the critical ingredient to realizing that full vision. We develop integration products and services for Bonterra Case Management software to support the deployment of automations for a variety of use cases.
This video focuses on the notifications, alerts, and approval requests using Slack for Bonterra Impact Management. The solutions covered in this webinar can also be deployed for Microsoft Teams.
Interested in deploying notification automations for Bonterra Impact Management? Contact us at sales@sidekicksolutionsllc.com to discuss next steps.
DevOps and Testing slides at DASA ConnectKari Kakkonen
My and Rik Marselis slides at 30.5.2024 DASA Connect conference. We discuss about what is testing, then what is agile testing and finally what is Testing in DevOps. Finally we had lovely workshop with the participants trying to find out different ways to think about quality and testing in different parts of the DevOps infinity loop.
Kubernetes & AI - Beauty and the Beast !?! @KCD Istanbul 2024Tobias Schneck
As AI technology is pushing into IT I was wondering myself, as an “infrastructure container kubernetes guy”, how get this fancy AI technology get managed from an infrastructure operational view? Is it possible to apply our lovely cloud native principals as well? What benefit’s both technologies could bring to each other?
Let me take this questions and provide you a short journey through existing deployment models and use cases for AI software. On practical examples, we discuss what cloud/on-premise strategy we may need for applying it to our own infrastructure to get it to work from an enterprise perspective. I want to give an overview about infrastructure requirements and technologies, what could be beneficial or limiting your AI use cases in an enterprise environment. An interactive Demo will give you some insides, what approaches I got already working for real.
Connector Corner: Automate dynamic content and events by pushing a buttonDianaGray10
Here is something new! In our next Connector Corner webinar, we will demonstrate how you can use a single workflow to:
Create a campaign using Mailchimp with merge tags/fields
Send an interactive Slack channel message (using buttons)
Have the message received by managers and peers along with a test email for review
But there’s more:
In a second workflow supporting the same use case, you’ll see:
Your campaign sent to target colleagues for approval
If the “Approve” button is clicked, a Jira/Zendesk ticket is created for the marketing design team
But—if the “Reject” button is pushed, colleagues will be alerted via Slack message
Join us to learn more about this new, human-in-the-loop capability, brought to you by Integration Service connectors.
And...
Speakers:
Akshay Agnihotri, Product Manager
Charlie Greenberg, Host
Key Trends Shaping the Future of Infrastructure.pdfCheryl Hung
Keynote at DIGIT West Expo, Glasgow on 29 May 2024.
Cheryl Hung, ochery.com
Sr Director, Infrastructure Ecosystem, Arm.
The key trends across hardware, cloud and open-source; exploring how these areas are likely to mature and develop over the short and long-term, and then considering how organisations can position themselves to adapt and thrive.
Essentials of Automations: Optimizing FME Workflows with ParametersSafe Software
Are you looking to streamline your workflows and boost your projects’ efficiency? Do you find yourself searching for ways to add flexibility and control over your FME workflows? If so, you’re in the right place.
Join us for an insightful dive into the world of FME parameters, a critical element in optimizing workflow efficiency. This webinar marks the beginning of our three-part “Essentials of Automation” series. This first webinar is designed to equip you with the knowledge and skills to utilize parameters effectively: enhancing the flexibility, maintainability, and user control of your FME projects.
Here’s what you’ll gain:
- Essentials of FME Parameters: Understand the pivotal role of parameters, including Reader/Writer, Transformer, User, and FME Flow categories. Discover how they are the key to unlocking automation and optimization within your workflows.
- Practical Applications in FME Form: Delve into key user parameter types including choice, connections, and file URLs. Allow users to control how a workflow runs, making your workflows more reusable. Learn to import values and deliver the best user experience for your workflows while enhancing accuracy.
- Optimization Strategies in FME Flow: Explore the creation and strategic deployment of parameters in FME Flow, including the use of deployment and geometry parameters, to maximize workflow efficiency.
- Pro Tips for Success: Gain insights on parameterizing connections and leveraging new features like Conditional Visibility for clarity and simplicity.
We’ll wrap up with a glimpse into future webinars, followed by a Q&A session to address your specific questions surrounding this topic.
Don’t miss this opportunity to elevate your FME expertise and drive your projects to new heights of efficiency.
Builder.ai Founder Sachin Dev Duggal's Strategic Approach to Create an Innova...Ramesh Iyer
In today's fast-changing business world, Companies that adapt and embrace new ideas often need help to keep up with the competition. However, fostering a culture of innovation takes much work. It takes vision, leadership and willingness to take risks in the right proportion. Sachin Dev Duggal, co-founder of Builder.ai, has perfected the art of this balance, creating a company culture where creativity and growth are nurtured at each stage.
UiPath Test Automation using UiPath Test Suite series, part 3DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 3. In this session, we will cover desktop automation along with UI automation.
Topics covered:
UI automation Introduction,
UI automation Sample
Desktop automation flow
Pradeep Chinnala, Senior Consultant Automation Developer @WonderBotz and UiPath MVP
Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
6. Organisms belonging to the genus Mycobacterium are---- 1.Very Thin 2.Rod shaped 3.0.2 to 0.4 X 2 to 10 µ m 4.Non motile 5.Sometimes showing filamentous branching like fungus. 6.Forming mould like pellicle in liquid culture. HENCE CALLED MYCOBACTERIA
17. CMN Group: Unusual cell wall lipids (mycolic acids,etc.) ( P urified P rotein D erivative) Lipid Rich Cell Wall Of Mycobacterium tuberculosis Mycolic acids
18.
19. ACID FASTNESS OF MYCOBACTERIUM TUBERCULOSIS IS DUE TO PRESENCE OF A HIGH MOLECULAR WEIGHT HYDROXY ACID CONTAINING CARBOXYL GROUPS CALLED MYCOLIC ACID IN THE BACTERIAL CELL WALL OR TO A SEMIPERMIABLE MEMBRANE AROUND THE CELL.
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24. Colonies of Mycobacterium tuberculosis on Lowenstein-Jensen medium.
41. Diagram of a Granuloma NOTE: ultimately a fibrin layer develops around granuloma (fibrosis) , further “walling off” the lesion. Typical progression in pulmonary TB involves caseation , calcification and cavity formation .
47. She has tuberculosis of peripheral lymph nodes. Although lymphatic tuberculosis may appear to be a localized disease process, it is not as the systemic signs and symptoms in this child indicate. At least five lesions can be seen, but it is likely that there are more less apparent ones in deeper structures.
48.
49. This patient was referred to the tuberculosis clinic with the question of otitis media. There was no otitis. The patient had lost weight and had signs and symptoms of systemic illness. The pre-auricular lesion was cold to the touch and was apparently fluctuating. The abscess was aspirated. A Gram stain showed no organisms and careful examination of a Ziehl-Neelsen stained smear revealed acid-fast bacilli.
50. While peripheral lymphatic tuberculosis is most frequently found around the neck, the axilla may also affected. Several lymph nodes may be matted together as in this patient. Some nodes have undergone liquefaction leading to discoloration of the skin.
51. In this patient, any affected lymph node in the lesion had undergone complete caseation with discoloration of the skin.
52. This abscess was close to breaking through the skin, yet it felt cold to the touch and the child felt remarkably little pain when the lesion was touched. Such a finding should raise a high index of suspicion for tuberculosis.
53. This patient has chronic peripheral lymphatic tuberculosis with some lesions healed with scaring, while others are still showing activity.
54. This patient had a seven-year history of lymphatic tuberculosis. Many lesions have apparently healed, but some are still active (note inflammation surrounding the most caudal axillary lesion).
55. At first sight, all of the lesions resulting form peripheral lymphatic tuberculosis in this patient have healed. However, as the example of the previous patient demonstrates, one can never be certain. It thus may be good policy to offer curative chemotherapy to any patient with signs of tuberculosis of peripheral lymph nodes.
56. This boy presented with several lesions. On a chest radiograph, he had a segmental lesion. In addition, he had a lesion in the neck (rendered dark by traditional medicine), an axillary lesion, and a lesion in the arm (the hump on the arm is the tuberculin skin test reaction), and the hand.
58. This patient with tuberculosis of the spine and a visible abscess, slightly discoloring the overlaying skin, on the lower left back almost escaped a correct diagnosis but for an astute laboratory technician. The abscess was warm to the touch and a Gram stain showed Gram-positive cocci. Nevertheless, the laboratory technician insisted on rigorous examination for acid-fast bacilli and found them, confirming tuberculosis of the spine with a super-infected abscess.
59. The vertebral lesions are usually anterior in location, often triangular in shape. The bony structure adjacent to both sides of the disk becomes eroded, leading to the seemingly narrowing of inter-vertebral disk space.
60. As a result of the anterior lesion, the disk or disks collapse, building a triangular shape, leading the typical gibbus
63. In addition to the paralysis caused by the lower lumbar lesion, this child also had a pyopneumothorax (and an accelerated response to a BCG vaccination).
65. This patient with a 90 degree lesion in the spine was ambulatory when interviewed. He had had received a full course of anti-tuberculosis treatment and had no neurologic symptoms.
66. The reason for the complete recovery from neurologic symptoms in the majority of patients is most likely attributable to the anterior location of the disease process that often leaves the spinal canal spared. The neurologic symptoms seen in the beginning are thus most likely attributable to edema and compression from abscesses that resolve with chemotherapy. In some patients, boney particles may, however, reach the spinal canal and then may cause permanent disability.
67. This girl had an almost completely destroyed hip joint.
68. The diagnosis of tuberculosis of the left hip in this boy was made from the secretion from a sinus draining through the skin by demonstrating acid-fast bacilli.
70. This patient has a sinus draining from both the dorsal and volar aspect of the thumb. He squeezed pus out from the lesions directly onto a Lowenstein-Jensen medium, on which Mycobacterium tuberculosis was isolated (a smear examination for acid-fast bacilli was negative).
72. This patient had tuberculosis of the ankle. The bacteriologic diagnosis was made by demonstrating acid-fast bacilli from the visible secretions draining from a sinus.
73. The patient did not only have tuberculosis of the ankle, he also had peripheral lymphatic tuberculosis, tuberculous mastitis (exceedingly rare in men), pleural thickening from past pleural tuberculosis, multiple abscesses, and had been operated for a presumable tuberculous epididymitis. While such multi-system disease in a young man should pose little difficulties in making the diagnosis of tuberculosis, it had not been taken into consideration for a prolonged period of time.
74. The patient did not only have tuberculosis of the ankle, he also had peripheral lymphatic tuberculosis, tuberculous mastitis (exceedingly rare in men), pleural thickening from past pleural tuberculosis, multiple abscesses, and had been operated for a presumable tuberculous epididymitis. While such multi-system disease in a young man should pose little difficulties in making the diagnosis of tuberculosis, it had not been taken into consideration for a prolonged period of time.
75. The diagnosis of female genitourinary tuberculosis is probably made in only of a fraction of cases. It is believed, however, that Falloppian tube and endometrial tuberculosis may account for much female infertility in high-incidence countries. This patient is an example to the case: an observant clinician requested a histological examination of an endometrium biopsy specimen and caseous granulomata were reported. Subsequently, the index of suspician rose, and numerous other cases were diagnosed subsequently.
76. Warty skin tuberculosis is a perhaps difficult to diagnose manifestation of tuberculosis of the skin if it is not thought of. This patient testifies to the remarkable efficacy of modern anti-tuberculosis chemotherapy in such a patient.
77. Tuberculosis of the spine is most frequently located in the lower thoracic and the lumber region of the spine.
Once a tubercle is formed, the immune system is activated, but by this time the bacteria may have already spread to other bronchi (Reviewed by Schaff, et al. , 2003). Necrosis occurs in the center of tubercles because of the toxins secreted by the surrounding immune cells. The caseous centers of tubercles liquefy, the bacteria continue to multiply, and then bronchi necrosis occurs. TB is often associated with caseous necrosis, which resembles soft white cheese. Fisher (2002) noted that most well-nourished and immunocompetent individuals can eliminate the bacteria before a more serious condition occurs. In 90% of cases, the bacteria are eliminated and the tubercle heals, evidenced by scar formation. On close inspection, the caseous tan necrotic tissue in this image constitutes the granulomas in this lung.
Infection begins as T-lymphocytes secrete cytokines that recruit macrophages in response to the presence of the pathogen (Reviewed by Sharma and Mohran, 2004). These macrophages accumulate and aggregate in tissues to become spherical granulomas. Granulomas prevent the spread of M. tuberculosis by confining the bacteria in a compact area where the immune cells can work together to isolate and destroy the bacteria. The central zones of granulomas contain large macrophages surrounded by T-lymphocytes. Granulomas in TB are called tubercles and are visible as white spots (1-2 mm). Once in the alveoli, the bacteria can then spread to local lymph nodes, the bloodstream, and eventually, to distant organs (lung apices, peripheral lymph nodes, kidneys, brain, and bone).