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Presented by: Nesar Ahmad
Moderator: Dr Raghib Hussain
Aktc. d/o jarahat
10/07/2017
ANATOMY of
kidney
Introduction
• Urinary system comprises the kidneys, ureters,
urinary bladder, and urethra.
• The structures of kidney precisely maintain the
internal chemical environment of the body—perform
various excretory and regulatory functions.
EMBRYOLOGY
• Development starts at 4th week
• The urogenital glands and ducts develop from the intermediate
mesoderm.
• primordial components ----pronephros ,mesonephros,metanephros ,
and the mesonephric and paramesonephric ducts.
• pronephros :appear as solid cell groups in cervical region ,which then
regresses
• mesonephros : forms glomerulus bowman’s capsule, which opens
into mesonephric duct
• except mesonephric duct rest of these structures regresses
• mesonephric duct forms internal genitalia in males , an out growth
from it forms ureteric bud
 metanephros forms excretory part of
definitive kidney upto DCT
 ureteric bud forms the rest, from collecting
tubules upto trigone of the bladder
 interaction between metanephros and ureteric
bud initiates development of kidney
Kidneys
LOCATION:
 The Kidneys (renes) are a pair of excretory organs situated
on the posterial abdominal wall, one on each side of
vertebral column, covered by the peritoneum and
surrounded by a mass of fat and loose areolar tissue.
 The kidneys occupy the epigastric, hypochondriac, lumbar
and umblical regions
 Vertically they extend from the upper border of twelfth
thoracic vertebra to the center of the body of third lumbar
vertebra.
The right kidney is usually slightly lower than the left,
and the left kidney is a little nearer to the median plane than
the right.
The tranpyloric plane passes through the upper part of the
hilus of the right kidney, and through the lower part of the
hilus of the left kidney.
The long axis of each kidney is directed downwards and
laterally.
The upper poles of kidneys are more medial and posterior
than the inferior poles.
Kidneys
COLOUR AND SHAPE:
Reddish brown in colour and bean shaped.
HEIGHT & WEIGHT:
• Each kidney is about 11cm long, 6 cm wide, and rather
more than 2.5 cm thick. The left is somewhat longer and
narrower than the right.
• In the adult male, the kidney weighs 125 to 170 gm; in the
adult female, 115 to 155 gm.
• The combined weight of the two kidneys in proportion to
that of the body is about 1:240.
• The newborn kineys in proportion to the body weight are
about three times larger than the adult kidneys.
11 cm
6cm
3cm
10
Surface marking
The kidney can be marked both on the back as well as
on the front.
On the back: it is marked within Morris
parellelogram which is drawn in the following way.
2 horizontal lines-T11 & L3 spine
2 vertical lines- 2.5 & 9cm from median plane
Hilum 5cm from median plane,near the level of
transpyloric plane,
Little above it in the left
Little below it in the right
On the front: the bean shaped kidney is marked
with the following specifications:
1) On the right side the center of the hilum lies
5cm from the median plane, a little below the
transpyloric plane.
On the left side it lies 5cm from the median plane,
a little above the transpyloric plane.
2) the upper pole lies 4 to 5cm from the midline,
halfway between the xiphisternum and the
transpyloric plane right one, a little lower.
3) The lower pole lies 6 to 7cm from the midline
on the right side at the umblical plane and on the
left side at the subcostal plane.
CAPSULES OR COVERINGS OF
KIDNEYS• Fibrous capsule –
– Thin membrane, covers the kidneys, may be separated from them
• Perirenal fat –
– Layer of fat surrounding the fibrous capsule and also filling up area in
the renal sinus
• Renal fascia of Gerota-
– Fibroareolar sheath surrounding the kidney and perirenal fat
– helps maintain organ position
– superiorly, is continuous with fascia of inferior diaphragm
– medially the left and right fascia blend with each other anterior to
abdominal aorta and IVC
– posterior layer of fascia blends with fascia overlying psoas
Anterior layer– fascia of Toldt
Posterior layer – fascia of Zucherkandl
• Pararenal fat –
– Fat that surrounds the renal fascia, more abundant posteriorly and at
lower pole
– Fills up paravertebral gutter and forms a cushion for the kidney
Relations of kidney with other
organs and structures
kidney has :
Two poles (extremity) –
– Upper/cranial extremity – broad due to presence of adrenal
glands
– Lower/caudal extremity – pointed
Two borders
– Lateral – convex
– Medial – concave with hilum in the middle
Two surfaces
– Anterior – irregular
– Posterior - flat
Surfaces
Ventral/anterior surface:
The ventral surface of each kidney is convex and
faces ventralward and slightly lateralward
Anterior surfaces right kidney
It’s relations
Upper part
With right suprarenal glands
With the visceral surface of the liver
With second part of duodenum
Lower part
Laterally With right colic (hepatic) flexure of
ascending colon
Medially With small intestine
Anterior surface of left kidney
It’s relations:
Left suprarenal gland
Spleen
Body of pancreas
Left renal vessels
Posterior surface of stomach
Splenic flexure
jejunum
Peritoneum of omental bursa
Peritoneum of the greater sac
The ventral surfaces of the kidneys, showing the areas of contact of neighboring viscera
Posterior/Dorsal surface
The posterior surface of each kidney is directed dorsalward and
medialward.
It is embeded in areolar and fatty tissue and entirely devoid of
peritoneal covering.
It’s relations
Diaphragm
Medial and lateral lumbocostal arches
Muscles: psoas major, quadratus lumborum, tendon of
transversus abdominis
Arteries: subcostal and one or two of the upper lumbar arteries
Nerves: subcostal, iliohypogastric and ilioinguinal nerves
On the right side: 12th rib
On the left side: 11th & 12th ribs both
The dorsal surfaces of the kidneys, showing areas of relation to the parietes
Borders
Kidney has two borders
1. Lateral border (external border): is convex and and
directed towards the posterolateral wall of the
abdomen. On the left side it is in contact with the
spleen.
2. Medial border (internal border): is concave in the
center and convex toward either extremity; it is
directed anteriorly and a little downward. Its central
part has a deep longitudinal fissure. This fissure
named the Hilum, transmits the renal vessels, renal
nerves and pelvis. Above the hilum the medial border
is in relation with the suprarenal gland; below the
hilum, with the ureter.
The medial border
Extremities
1. Cranial extremity (upper pole): is thick and round and
is nearer the median line than the caudal extremity. It is
surrounded by suprarenal gland.
2. Caudal extremity (lower pole): is smaller and thinner
than the superior and farther from the median line.
General structure of the kidney
The kidney is invested by a fibrous tunic or capsule that forms a
firm, smooth covering to the organ. The tunic can be stripped off
easily, so the surface of the kidney becomes smooth and deep
red.
If a vertical section of the kidney were made from its convex to
its concave border, it would be seen that the hilum expands into
a central cavity, the renal sinus; this contains the renal pelvis
and the calyces, surrounded by some fat in which the branches
of the renal vessels and nerves are embedded.
The minor renal calyces, numbering 4 to 13, are cup shaped
tubes. They unite to form two or three short tubes, the major
calyces, and these in turn join to form a funnel-shaped sac, the
renal pelvis.
As the pelvis leaves the renal sinus, it diminishes rapidly in
caliber and merges insensibly into the ureter, the excretory duct
of the kidney
The kidney is composed of an internal medullary and an
external cortical substance.
The medullary substance consist of a series of striated
conical masses, termed the renal pyramids, of which there
are 8 to 18. Their bases are directed toward the
circumference of the kidney, while their apices converge
toward the renal sinus, where they form prominent papillae
projecting into the lumen of the minor calyces.
The cortical substance is reddish brown, soft and granular.
It lies immediately beneath the fibrous tunic, arches over the
bases of the pyramids, and dips in between adjacent
pyramids toward the renal sinus. The parts dipping between
the pyramids are named renal columns, while the portions
that connect the renal columns to each other and intervene
between the bases of the pyramids and the fibrous tunic are
called the cortical arches.
GROSS STRUCTURE OF THE KIDNEY
Longitudinal section there are 3 areas.
I. Fibrous capsule
II. Cortex
III. Medulla
33
RENAL FIBROUS CAPSULE: surrounds the kidney,
made of dense fibrous connective tissue.
34
CORTEX: A reddish brown layer of tissue
immediately below the capsule and out side the
pyramids.
35
MEDULLA: the inner most layer consisting of pale
conical shaped striations called renal pyramids.
Surface anatomy of the Kidney
• Hilum is located on
the medial surface
HILUM: it is the concave medial border or deep
fissure of the kidney where the renal blood & lymph
vessels , urater & nerve enters.
Renal Sinus:
Space within hilus.
Kidneys receive
blood vessels and
nerves.
37
RENAL PELVIS: it is the funnel shaped structure
which acts as a receptacle of the urine formed by
the kidney.
Renal Vasculature
• Renal arteries branch from the abdominal aorta
laterally between L1 and L2, below the origin of the
superior mesenteric artery
• The right renal artery passes posterior to the IVC
• There may be more than one renal artery (on one or
both sides) in 20-30% cases
Renal Vasculature
• Renal veins drain into inferior vena cava
• Renal veins lie anterior to the arteries
• Left renal vein is longer and passes anterior to the
aorta before draining into the inferior vena cava.
Aorta
Renal artery
Segmental artery
Interlobar artery
Arcuate artery
Interlobular artery
Afferent arteriole
Glomerulus (capillaries)
Nephron-associated blood vessels
Inferior vena cava
Renal vein
Interlobar vein
Arcuate vein
Cortical radiate
vein / interlobular vein
Peritubular
capillaries
and vasa recta
Efferent arteriole
Path of blood flow through renal blood vessels
Regulates blood flow to the kidney by
causing vasodilation or vaso constriction of
renal arterioles.
Autonomic plexuses in the abdomen and pelvis
Renal Lymphatics
The lymphatics of the kidney drain into the lateral
aortic nodes located at the level of origin of the
renal arteries
Histological structures of the kidney
Histologically each kidney is composed of 1-3
million uriniferous tubules. Each tubule consists of
two parts.
1) The secretory part, called the nephron, which is
the functional unit of the kidney. It comprises two
parts.
a) Renal corpuscle or Malphigian corpscle; made up
of glomerulus and Bowman’s capsule
b) Renal tubule; made up of the proximal
convoluted tubule, loop of Henle with its
descending and ascending limbs, and the distal
convoluted tubule.
2) Collecting tubule: which begins as a junctional
tubule from the distal convoluted tubule. Many
tubules unite together to forms the ducts of Bellini
which open into the minor calices through the renal
papillae.
Kidneys functions
• Urine formation
• Excretion of waste products
• Regulation of electrolytes
• Regulation of acid–base balance
• Control of water balance
• Control of blood pressure
• Renal clearance
• Regulation of red blood cell production
• Synthesis of vitamin D to active form
• Secretion of prostaglandins
Applied anatomy
Congenital anomalies of the kidney:
Agenesis of kidney: absence of kiney on one side is often
associated with absence of ureter, either one kidney is absent
with ureter or ureter and pelvis is present but the kidney is
absent. In both these cases the present single kidney
becomes hypertrophied and functions almost double the
normal
Hypoplasia and Dysplasia: when the metanephrogenic cap
fails to develop properly, such condition may develop when
one kidney becomes small and less functioning.
Supernumerary kidney: there may be more than one kidney
on one or both sides.
Duplex kidney & ureter: Sometimes the pelvis is
duplicated, while a double ureter is not uncommon.
Foetal lobulation: in the foetal life the kidney is lobulated
and is made up about 12 lobules, after birth the lobules
gradually fuse, however the evidence of foetal lobulation
may persists.
Fused kidney: three types are found:-
1) Horse shoe kidney is caused by fusion of lower poles of
both kidneys with a bridge.
2) Unilateral fused kidney or crossed renal ectopia: in
which both kidneys may lie on any one side of the body.
3) S-shaped kidney
Defect in the position of the kidney or ectopic kidney: One or both
kidneys may be misplaced congenitally and remain fixed in this
abnormal position. They may be displaced into the iliac fossa, over
the sacroiliac joint, onto the promontary of the sacrum, or into the
pelvis between the rectum and bladder.
Floating kidney: The kidney may also be displaced congenitally
but not fixed.they can move up and down within the renal fascia, but
not from side to side.
Movable kidney: The kidney may also be misplaced as an acquired
condition; in these cases the kidney is mobile in the tissues that
surround it, moving with the capsule in the perinephric tissues.
Cystic disorders of the kidney: Nonunion of the secratory and
collecting parts of the kidney results in the formation of either
polycystic kidney or medullary sponge kidney or unilateral
multicystic kidney or solitary renal cyst.
Renal arteriovenous fistula: may be congenital in 25% of cases
Applied anatomy cont...........
• Renal injuries
• Perinephric abcess
• Nephroptosis
• Renal cyst
• Renal calculi
• Glomerular nephritis
• Renal transplantation
Renal injuries
Renal injuries can be classified into slight, severe and critical.
Slight injuries comprise those where the parenchyma is
damaged without rupture of the capsule or extension of the
laceration into the renal pelvis or calyx. This produces
subscapular haematoma. This condition does not produce
haematuria but slight tenderness at the renal angle can be
elicited.
Severe injuries are those where the capsule is broken, renal
pelvis or calyx is distorted. This produces haematuria or a mass
in the loin from a perirenal haematoma. There may be leakage
of urine in the retroperitoneal tissue.
Critical injury is such when the kidney is shattered or there is a
tear in the renal artery or one of its branches. The patient rarely
survives after this type of injury.
Perinephric abcess
o Pus around the kidney
o The attachment of renal facia determine the path
of extension of perinephric abcess.
o The pus from abcess may force its way into
pelvis between the loosely attached anterior and
posterior attached layers of renal fascia.
Nephroptosis
• Because the renal fascia do not fuse firmly
inferiorly to offer resistance, abnormaly mobile
kidney may descend more than 3cm to their
normal position when body is erect.
• Distinguished from an ectopic kidney by the
length of ureter.
Renal cyst
• Solitary or multiple
• Adult polycystic disease of kidney is an
important cause of renal failure.
• The kidneys are markedly increased by 5 cm of
the normal size.
Renal calculi
• Description: common cause of urine obstruction
• Etiology: low urine volume, dehydration, UTI,
prolonged bedrest
• Four types of kidney stones:
– Calcium stones (i.e., oxalate or phosphate)
– Magnesium ammonium phosphate stones
– Uric acid stones
– Cystine stones
Glomerular nephritis
• Glomerular nephritis refers to an inflammation of
the glomerulas .
• Results in nephrotic syndrome.
• Oedema
• Increased protein in urine.
• decreased protein in urine.
Hydronephritis
• Expansion of the kidney with urine
– Increased pressure inside the renal capsule
– Compartment syndrome compresses blood
vessels inside kidney
– Renal ischemia
Renal transplantation
• Established operation for chronic renal failure.
• Kidney can be removed from donor without
damaging the supra renal gland because of
weak septum of renal fascia that separates the
kidney from this gland.
• Site- iliac fossa of greater pelvis.
• Renal artery and veins are joined to the external
iliac artery and vein respectively. Ureter is
sutured.
Questions?

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Anatomy of kidney - Dr Nesar, AKTC, AMU, Aligarh

  • 1. Presented by: Nesar Ahmad Moderator: Dr Raghib Hussain Aktc. d/o jarahat 10/07/2017 ANATOMY of kidney
  • 2. Introduction • Urinary system comprises the kidneys, ureters, urinary bladder, and urethra. • The structures of kidney precisely maintain the internal chemical environment of the body—perform various excretory and regulatory functions.
  • 3.
  • 4. EMBRYOLOGY • Development starts at 4th week • The urogenital glands and ducts develop from the intermediate mesoderm. • primordial components ----pronephros ,mesonephros,metanephros , and the mesonephric and paramesonephric ducts. • pronephros :appear as solid cell groups in cervical region ,which then regresses • mesonephros : forms glomerulus bowman’s capsule, which opens into mesonephric duct • except mesonephric duct rest of these structures regresses • mesonephric duct forms internal genitalia in males , an out growth from it forms ureteric bud
  • 5.  metanephros forms excretory part of definitive kidney upto DCT  ureteric bud forms the rest, from collecting tubules upto trigone of the bladder  interaction between metanephros and ureteric bud initiates development of kidney
  • 6. Kidneys LOCATION:  The Kidneys (renes) are a pair of excretory organs situated on the posterial abdominal wall, one on each side of vertebral column, covered by the peritoneum and surrounded by a mass of fat and loose areolar tissue.  The kidneys occupy the epigastric, hypochondriac, lumbar and umblical regions  Vertically they extend from the upper border of twelfth thoracic vertebra to the center of the body of third lumbar vertebra.
  • 7.
  • 8. The right kidney is usually slightly lower than the left, and the left kidney is a little nearer to the median plane than the right. The tranpyloric plane passes through the upper part of the hilus of the right kidney, and through the lower part of the hilus of the left kidney. The long axis of each kidney is directed downwards and laterally. The upper poles of kidneys are more medial and posterior than the inferior poles.
  • 9. Kidneys COLOUR AND SHAPE: Reddish brown in colour and bean shaped. HEIGHT & WEIGHT: • Each kidney is about 11cm long, 6 cm wide, and rather more than 2.5 cm thick. The left is somewhat longer and narrower than the right. • In the adult male, the kidney weighs 125 to 170 gm; in the adult female, 115 to 155 gm. • The combined weight of the two kidneys in proportion to that of the body is about 1:240. • The newborn kineys in proportion to the body weight are about three times larger than the adult kidneys.
  • 11. Surface marking The kidney can be marked both on the back as well as on the front. On the back: it is marked within Morris parellelogram which is drawn in the following way. 2 horizontal lines-T11 & L3 spine 2 vertical lines- 2.5 & 9cm from median plane Hilum 5cm from median plane,near the level of transpyloric plane, Little above it in the left Little below it in the right
  • 12.
  • 13. On the front: the bean shaped kidney is marked with the following specifications: 1) On the right side the center of the hilum lies 5cm from the median plane, a little below the transpyloric plane. On the left side it lies 5cm from the median plane, a little above the transpyloric plane. 2) the upper pole lies 4 to 5cm from the midline, halfway between the xiphisternum and the transpyloric plane right one, a little lower. 3) The lower pole lies 6 to 7cm from the midline on the right side at the umblical plane and on the left side at the subcostal plane.
  • 14.
  • 15. CAPSULES OR COVERINGS OF KIDNEYS• Fibrous capsule – – Thin membrane, covers the kidneys, may be separated from them • Perirenal fat – – Layer of fat surrounding the fibrous capsule and also filling up area in the renal sinus • Renal fascia of Gerota- – Fibroareolar sheath surrounding the kidney and perirenal fat – helps maintain organ position – superiorly, is continuous with fascia of inferior diaphragm – medially the left and right fascia blend with each other anterior to abdominal aorta and IVC – posterior layer of fascia blends with fascia overlying psoas Anterior layer– fascia of Toldt Posterior layer – fascia of Zucherkandl • Pararenal fat – – Fat that surrounds the renal fascia, more abundant posteriorly and at lower pole – Fills up paravertebral gutter and forms a cushion for the kidney
  • 16.
  • 17.
  • 18. Relations of kidney with other organs and structures kidney has : Two poles (extremity) – – Upper/cranial extremity – broad due to presence of adrenal glands – Lower/caudal extremity – pointed Two borders – Lateral – convex – Medial – concave with hilum in the middle Two surfaces – Anterior – irregular – Posterior - flat
  • 19. Surfaces Ventral/anterior surface: The ventral surface of each kidney is convex and faces ventralward and slightly lateralward
  • 20. Anterior surfaces right kidney It’s relations Upper part With right suprarenal glands With the visceral surface of the liver With second part of duodenum Lower part Laterally With right colic (hepatic) flexure of ascending colon Medially With small intestine
  • 21. Anterior surface of left kidney It’s relations: Left suprarenal gland Spleen Body of pancreas Left renal vessels Posterior surface of stomach Splenic flexure jejunum Peritoneum of omental bursa Peritoneum of the greater sac
  • 22. The ventral surfaces of the kidneys, showing the areas of contact of neighboring viscera
  • 23. Posterior/Dorsal surface The posterior surface of each kidney is directed dorsalward and medialward. It is embeded in areolar and fatty tissue and entirely devoid of peritoneal covering. It’s relations Diaphragm Medial and lateral lumbocostal arches Muscles: psoas major, quadratus lumborum, tendon of transversus abdominis Arteries: subcostal and one or two of the upper lumbar arteries Nerves: subcostal, iliohypogastric and ilioinguinal nerves On the right side: 12th rib On the left side: 11th & 12th ribs both
  • 24. The dorsal surfaces of the kidneys, showing areas of relation to the parietes
  • 25.
  • 26. Borders Kidney has two borders 1. Lateral border (external border): is convex and and directed towards the posterolateral wall of the abdomen. On the left side it is in contact with the spleen. 2. Medial border (internal border): is concave in the center and convex toward either extremity; it is directed anteriorly and a little downward. Its central part has a deep longitudinal fissure. This fissure named the Hilum, transmits the renal vessels, renal nerves and pelvis. Above the hilum the medial border is in relation with the suprarenal gland; below the hilum, with the ureter.
  • 28. Extremities 1. Cranial extremity (upper pole): is thick and round and is nearer the median line than the caudal extremity. It is surrounded by suprarenal gland. 2. Caudal extremity (lower pole): is smaller and thinner than the superior and farther from the median line.
  • 29. General structure of the kidney The kidney is invested by a fibrous tunic or capsule that forms a firm, smooth covering to the organ. The tunic can be stripped off easily, so the surface of the kidney becomes smooth and deep red. If a vertical section of the kidney were made from its convex to its concave border, it would be seen that the hilum expands into a central cavity, the renal sinus; this contains the renal pelvis and the calyces, surrounded by some fat in which the branches of the renal vessels and nerves are embedded. The minor renal calyces, numbering 4 to 13, are cup shaped tubes. They unite to form two or three short tubes, the major calyces, and these in turn join to form a funnel-shaped sac, the renal pelvis. As the pelvis leaves the renal sinus, it diminishes rapidly in caliber and merges insensibly into the ureter, the excretory duct of the kidney
  • 30. The kidney is composed of an internal medullary and an external cortical substance. The medullary substance consist of a series of striated conical masses, termed the renal pyramids, of which there are 8 to 18. Their bases are directed toward the circumference of the kidney, while their apices converge toward the renal sinus, where they form prominent papillae projecting into the lumen of the minor calyces. The cortical substance is reddish brown, soft and granular. It lies immediately beneath the fibrous tunic, arches over the bases of the pyramids, and dips in between adjacent pyramids toward the renal sinus. The parts dipping between the pyramids are named renal columns, while the portions that connect the renal columns to each other and intervene between the bases of the pyramids and the fibrous tunic are called the cortical arches.
  • 31.
  • 32. GROSS STRUCTURE OF THE KIDNEY Longitudinal section there are 3 areas. I. Fibrous capsule II. Cortex III. Medulla
  • 33. 33 RENAL FIBROUS CAPSULE: surrounds the kidney, made of dense fibrous connective tissue.
  • 34. 34 CORTEX: A reddish brown layer of tissue immediately below the capsule and out side the pyramids.
  • 35. 35 MEDULLA: the inner most layer consisting of pale conical shaped striations called renal pyramids.
  • 36. Surface anatomy of the Kidney • Hilum is located on the medial surface HILUM: it is the concave medial border or deep fissure of the kidney where the renal blood & lymph vessels , urater & nerve enters. Renal Sinus: Space within hilus. Kidneys receive blood vessels and nerves.
  • 37. 37 RENAL PELVIS: it is the funnel shaped structure which acts as a receptacle of the urine formed by the kidney.
  • 38. Renal Vasculature • Renal arteries branch from the abdominal aorta laterally between L1 and L2, below the origin of the superior mesenteric artery • The right renal artery passes posterior to the IVC • There may be more than one renal artery (on one or both sides) in 20-30% cases
  • 39. Renal Vasculature • Renal veins drain into inferior vena cava • Renal veins lie anterior to the arteries • Left renal vein is longer and passes anterior to the aorta before draining into the inferior vena cava.
  • 40. Aorta Renal artery Segmental artery Interlobar artery Arcuate artery Interlobular artery Afferent arteriole Glomerulus (capillaries) Nephron-associated blood vessels Inferior vena cava Renal vein Interlobar vein Arcuate vein Cortical radiate vein / interlobular vein Peritubular capillaries and vasa recta Efferent arteriole Path of blood flow through renal blood vessels
  • 41.
  • 42. Regulates blood flow to the kidney by causing vasodilation or vaso constriction of renal arterioles. Autonomic plexuses in the abdomen and pelvis
  • 43. Renal Lymphatics The lymphatics of the kidney drain into the lateral aortic nodes located at the level of origin of the renal arteries
  • 44. Histological structures of the kidney Histologically each kidney is composed of 1-3 million uriniferous tubules. Each tubule consists of two parts. 1) The secretory part, called the nephron, which is the functional unit of the kidney. It comprises two parts. a) Renal corpuscle or Malphigian corpscle; made up of glomerulus and Bowman’s capsule b) Renal tubule; made up of the proximal convoluted tubule, loop of Henle with its descending and ascending limbs, and the distal convoluted tubule.
  • 45. 2) Collecting tubule: which begins as a junctional tubule from the distal convoluted tubule. Many tubules unite together to forms the ducts of Bellini which open into the minor calices through the renal papillae.
  • 46.
  • 47. Kidneys functions • Urine formation • Excretion of waste products • Regulation of electrolytes • Regulation of acid–base balance • Control of water balance • Control of blood pressure • Renal clearance • Regulation of red blood cell production • Synthesis of vitamin D to active form • Secretion of prostaglandins
  • 48. Applied anatomy Congenital anomalies of the kidney: Agenesis of kidney: absence of kiney on one side is often associated with absence of ureter, either one kidney is absent with ureter or ureter and pelvis is present but the kidney is absent. In both these cases the present single kidney becomes hypertrophied and functions almost double the normal Hypoplasia and Dysplasia: when the metanephrogenic cap fails to develop properly, such condition may develop when one kidney becomes small and less functioning. Supernumerary kidney: there may be more than one kidney on one or both sides.
  • 49. Duplex kidney & ureter: Sometimes the pelvis is duplicated, while a double ureter is not uncommon. Foetal lobulation: in the foetal life the kidney is lobulated and is made up about 12 lobules, after birth the lobules gradually fuse, however the evidence of foetal lobulation may persists. Fused kidney: three types are found:- 1) Horse shoe kidney is caused by fusion of lower poles of both kidneys with a bridge. 2) Unilateral fused kidney or crossed renal ectopia: in which both kidneys may lie on any one side of the body. 3) S-shaped kidney
  • 50. Defect in the position of the kidney or ectopic kidney: One or both kidneys may be misplaced congenitally and remain fixed in this abnormal position. They may be displaced into the iliac fossa, over the sacroiliac joint, onto the promontary of the sacrum, or into the pelvis between the rectum and bladder. Floating kidney: The kidney may also be displaced congenitally but not fixed.they can move up and down within the renal fascia, but not from side to side. Movable kidney: The kidney may also be misplaced as an acquired condition; in these cases the kidney is mobile in the tissues that surround it, moving with the capsule in the perinephric tissues. Cystic disorders of the kidney: Nonunion of the secratory and collecting parts of the kidney results in the formation of either polycystic kidney or medullary sponge kidney or unilateral multicystic kidney or solitary renal cyst. Renal arteriovenous fistula: may be congenital in 25% of cases
  • 51. Applied anatomy cont........... • Renal injuries • Perinephric abcess • Nephroptosis • Renal cyst • Renal calculi • Glomerular nephritis • Renal transplantation
  • 52. Renal injuries Renal injuries can be classified into slight, severe and critical. Slight injuries comprise those where the parenchyma is damaged without rupture of the capsule or extension of the laceration into the renal pelvis or calyx. This produces subscapular haematoma. This condition does not produce haematuria but slight tenderness at the renal angle can be elicited. Severe injuries are those where the capsule is broken, renal pelvis or calyx is distorted. This produces haematuria or a mass in the loin from a perirenal haematoma. There may be leakage of urine in the retroperitoneal tissue. Critical injury is such when the kidney is shattered or there is a tear in the renal artery or one of its branches. The patient rarely survives after this type of injury.
  • 53. Perinephric abcess o Pus around the kidney o The attachment of renal facia determine the path of extension of perinephric abcess. o The pus from abcess may force its way into pelvis between the loosely attached anterior and posterior attached layers of renal fascia.
  • 54. Nephroptosis • Because the renal fascia do not fuse firmly inferiorly to offer resistance, abnormaly mobile kidney may descend more than 3cm to their normal position when body is erect. • Distinguished from an ectopic kidney by the length of ureter.
  • 55. Renal cyst • Solitary or multiple • Adult polycystic disease of kidney is an important cause of renal failure. • The kidneys are markedly increased by 5 cm of the normal size.
  • 56. Renal calculi • Description: common cause of urine obstruction • Etiology: low urine volume, dehydration, UTI, prolonged bedrest • Four types of kidney stones: – Calcium stones (i.e., oxalate or phosphate) – Magnesium ammonium phosphate stones – Uric acid stones – Cystine stones
  • 57. Glomerular nephritis • Glomerular nephritis refers to an inflammation of the glomerulas . • Results in nephrotic syndrome. • Oedema • Increased protein in urine. • decreased protein in urine.
  • 58. Hydronephritis • Expansion of the kidney with urine – Increased pressure inside the renal capsule – Compartment syndrome compresses blood vessels inside kidney – Renal ischemia
  • 59. Renal transplantation • Established operation for chronic renal failure. • Kidney can be removed from donor without damaging the supra renal gland because of weak septum of renal fascia that separates the kidney from this gland. • Site- iliac fossa of greater pelvis. • Renal artery and veins are joined to the external iliac artery and vein respectively. Ureter is sutured.
  • 60.