The liver is the largest internal organ, weighing about 1.5 kg, located in the upper abdominal cavity and functions in bile production, detoxification, glycogen storage, and protein synthesis. It has two anatomical regions: a smooth diaphragmatic surface and a visceral surface related to various organs. The liver consists of right and left lobes, each with independent blood and nerve supply, and notable features include the porta hepatis, which serves as a passage for key blood vessels and ducts.