The document discusses the cerebrospinal fluid (CSF) pathway, including its formation in the choroid plexus, flow from the lateral and third ventricles to the fourth ventricle and subarachnoid space, and resorption through arachnoid granulations. It also addresses hydrocephalus, noting its signs and symptoms in adults like headache and vomiting and in children like macrocephaly. Treatment options for hydrocephalus mentioned are ventriculoperitoneal shunting and endoscopic third ventriculostomy.

1. CSF Pathway
Obstruction &
Clinical correlates
Integrated Teaching session for 1st MBBS
Department of Neurosurgery
MGMCRI

2. CSF pathway
Lateral ventricles,Third Ventricle, Fourth Ventricle

3. CSF pathway – FormationCSF pathway
Formation: Choroid plexus

4. • Lateral
ventricles
• Third
ventricle
• Fourth
ventricle
CSF pathway
Formation: Choroid plexus

5. CSF pathway
Formation: Choroid plexus
CSF production
is an active
process – ATP
is spent

6. CSF pathway
Lateral ventricles-> Third Ventricle

7. CSF pathwayCSF pathway
Fourth Ventricle -> Subarachnoid space

8. CSF pathway
Spinal Subarachnoid space

9. CSF pathwayCSF pathway
CSF resorption: Arachnoid granulations

10. CSF pathway
CSF resorption: Arachnoid granulations

11. CSF pathway
Monro-Kelly Doctrine
Normal ICP:
5-15 mm Hg
Raised ICP:
> 20 mm Hg

12. CSF pathway
Hydrocephalus
MRI of normal ventricles MRI of dilated ventricles

13. CSF pathway
Hydrocephalus - Adult
Headache
Vomiting
Altered sensorium
Diplopia

14. CSF pathway
Hydrocephalus - Child
Macrocephaly
Persistent AF – Bulging
Sun setting sign

15. Hydrocephalus
Treatment – Ventriculoperitoneal shunt

16. Hydrocephalus
Treatment – Endoscopic Third Ventriculostomy