transport
in humans
learningOBJECTIVES
  At the end of the lesson, you should be able to:

- Explain why multi-cellular organisms such as human
   beings and plants need a transport system.
- Describe the parts of the human transport system –
   heart, vessels, blood.
- Describe the parts of the heart - atrium, ventricle. 4
   main vessels from and to the heart.
- Describe the different components of blood and
   their functions.
- Explain how blood acts as a transport medium.
- Explain how diffusion and osmosis are involved in the
   transport system.
- Describe double circulation.
funFACT



It would take about
1,200,000 mosquito bites
to completely drain the
average human of blood.

(Discover magazine,
August 2007)
whyTRANSPORT?




If you stay within 500 m – 1 km of the school,


you probably would not mind walking to school…
whyTRANSPORT?
whyTRANSPORT?




BUT if you stayed at Bedok, Woodlands, or even Boon
Lay…


You would probably take a form of public transport.
(or go to a school within walking distance…)


WHY?
whyTRANSPORT?
whyTRANSPORT?



Likewise, in unicellular organisms,

The cell is in direct contact with the external
environment.

Diffusion alone is enough to:
       - transport essential materials such as oxygen
       and nutrients to the cell
       - remove waste such as carbon dioxide rapidly
whyTRANSPORT?
whyTRANSPORT?



In multicellular (complex) organisms,

Cells are far from the external environment.

Diffusion alone is too slow to:
       - transport essential materials such as food to
       the various organs
       - remove waste products efficiently
whyTRANSPORT?



Thus, a transport system is developed to move these
substances
    eg. Blood system in humans

This will ensure
- a continual supply of nutrients, oxygen and other
useful materials for metabolism
- the removal of toxic waste products produced by
metabolism
circulatorySYSTEM

The human circulatory
system consists of three
parts:                       heart
• heart (pumps blood
                             blood
around the body)
                             vessels
• blood (liquid which
                             blood
carries materials)

• blood vessels (tubes
which carry blood around
the body)
theHEART




                        left atrium
right atrium




                         left ventricle


      right ventricle
theHEART
theHEART

• pumps blood around the body
• all mammals have hearts that are
similar in structure
• human heart is about the size of our
fists
• made up of cardiac muscles
• comprises 4 chambers
      2 upper chambers called atria
        (left and right)
      2 lower chambers called
        ventricles (left and right)
theHEART



• right side of heart pumps blood to
lungs only (which are a short
distance from the heart)
• left side of heart pumps blood
around the body (which are further
away from the heart)
• hence left ventricle has thicker
muscular walls than the right
ventricle
theHEART

                       The blood is then
   De-oxygenated pumped from the
              This blood passes
blood from the body ventricle out of
                      left            Oxygenated blood
                from the right
enters the right atrium heart to the restthe lungs enter
                                     from
           ventricle the out into
                      then
  and then into the                   the left atrium and
                   the lungsthe body
                           of
    right ventricle                     flow into the left
                                            ventricle




  Right atrium                           Left atrium

                                         Left ventricle
Right ventricle
theHEART

                 This blood passes         The blood is then
                   from the right          pumped from the
               ventricle then out into    left ventricle out of
                      the lungs          the heart to the rest
                                               of the body

   De-oxygenated                                            Oxygenated blood
blood from the body                                        from the lungs enter
enters the right atrium                                     the left atrium and
  and then into the                                           flow into the left
    right ventricle                                               ventricle

           Right atrium                               Left atrium

                                                      Left ventricle
         Right ventricle
bloodCIRCULATION




• In mammals, blood flows through the heart
twice in one complete circuit. This is known as
double circulation.
bloodCIRCULATION


       From the heart to the lungs and
       back to the heart,

       • In the lungs, the blood collects
       oxygen and releases carbon
       dioxide.
       • Blood that returns to the heart
       is now rich in oxygen, called
       oxygenated blood.
bloodCIRCULATION


       From the heart to the rest of the
       body and back to the heart,

       • As blood passes the small
       intestine, it collects digested
       food.
       • The blood supplies all the cells
       of the body with this digested
       food together with oxygen
       picked up in the lungs.
       • After oxygen is deposited in
       body tissues, the blood now has
       little oxygen, called
       deoxygenated blood.
systemicCIRCULATION
circulatorySYSTEM

The human circulatory
system consists of three
parts:                       heart
• heart (pumps blood
                             blood
around the body)
                             vessels
• blood (liquid which
                             blood
carries materials)

• blood vessels (tubes
which carry blood around
the body)
bloodCOMPONENTS
BLOOD
         Has two main functions:

          To carry materials round the body. These
         materials include nutrients, oxygen, carbon
         dioxide and other waste substances.

          To protect us against diseases.


                             BLOOD


plasma         red blood cells   white blood cells   platelets
bloodCOMPONENTS

                          BLOOD


            red blood cells   white blood cells      Platelets
plasma
             (erythrocytes)    (leukocytes)       (thrombocytes)


  PLASMA
  •Pale yellowish liquid

  •Contains mainly water (90%)

  •Contains mainly dissolved substances
   like nutrients (digested food), hormones,
  antibodies and waste products (carbon
  dioxide and urea).
bloodCOMPONENTS

                         BLOOD


           red blood cells   white blood cells      Platelets
plasma
            (erythrocytes)    (leukocytes)       (thrombocytes)

 •Contains haemoglobin

  gives RBC red colour when
 combined with oxygen; or
 purplish colour when
 combined with carbon dioxide

  combines reversibly with
 oxygen so RBC can transport
 oxygen around the body
bloodCOMPONENTS

                         BLOOD


           red blood cells   white blood cells      Platelets
plasma
            (erythrocytes)    (leukocytes)       (thrombocytes)

 •Does not contain nuclei

  More space to contain
 haemoglobin for oxygen
 transport
bloodCOMPONENTS

                         BLOOD


           red blood cells   white blood cells      Platelets
plasma
            (erythrocytes)    (leukocytes)       (thrombocytes)


  WHITE BLOOD CELLS
bloodCOMPONENTS

                         BLOOD


           red blood cells   white blood cells      Platelets
plasma
            (erythrocytes)    (leukocytes)       (thrombocytes)


  WHITE BLOOD CELLS
  •Much bigger in size than RBC

  •Fewer in number than RBC

  •Colourless (no haemoglobin)

  •Contains a nucleus
bloodCOMPONENTS

                          BLOOD


            red blood cells   white blood cells      Platelets
plasma
             (erythrocytes)    (leukocytes)       (thrombocytes)


  WHITE BLOOD CELLS
  •Two types:

          Phagocytes  Ingests foreign
           particles by phagocytosis

          Lymphocytes  Produces antibodies
           that neutralise bacteria and viruses
bloodCOMPONENTS

                          BLOOD

            red blood cells   white blood cells       Platelets
plasma
             (erythrocytes)    (leukocytes)       (thrombocytes)


  PLATELETS
  •Cell fragments (not complete cells)

  •No nucleus

  •Involved in the process of blood clotting
circulatorySYSTEM



The human circulatory
system consists of three       heart
parts:
                               blood
• blood                        vessels

• heart                        blood

• blood vessels
bloodVESSELS


• The blood vessels are a network of tubes to carry
blood around the body.

• Namely the artery, vein & capillary
bloodVESSELS - summary


               Artery             Vein          Capillary


Structure   Thick, elastic,    Thinner, less   One-cell thick
            muscular walls     elastic, less   endothelium
                              muscular walls

Functions      Transports       Transports      Transports
              blood away      blood towards     nutrients &
            from the heart       the heart        waste
                                                 materials
 Blood       High blood       Lowest blood      Low blood
            pressure from       pressure         pressure
Pressure        heart
bloodDISORDERS


Condition/      Description              Possible causes         Treatment
Disease
Haemophilia     Genetic illnesses that   Lack of one of the      No cure, controlled
                affect the ability of    clotting factors        by regular injection of
                blood to clot            caused by a deficient   the deficient clotting
                                         gene                    factor
Anaemia         Deficiency of red        Excessive blood loss,   Iron supplement,
                blood cells or           deficient blood cell    increased intake of
                haemoglobin              production (such as     food rich in iron,
                                         due to deficient iron   blood transfusion
                                         intake)
Leukaemia       Cancer of the blood      Exposure to             Chemotherapy, bone
                or bone marrow           radiation, certain      marrow transplant
                characterised by         chemicals or viruses,
                excessive production     genetic
                of usually white blood   predisposition
                cells
heartDISEASES



Disease        Description                          Possible causes            Treatment
Heart attack   Occurs when blood supply to a        Blood clot in heart        Ensure oxygen intake,
               part of the heart is interrupted     arteries                   bypass surgery,
               leading to damage or death of        Increased risk factor:     medications
               heart tissue                         smoking, excessive
                                                    alcohol consumption,
                                                    abuse of drugs, high
                                                    cholesterol,
                                                    hypertension,
                                                    diabetes, heart
                                                    diseases
Stroke         Rapid loss of brain function due     Blood clot,                Medications, ensure
               to interruption of blood supply to   haemorrhage (share         oxygen intake, surgery
               all or part of the brain             some of the risk
                                                    factors as heart attack)
bloodTRANSFUSION


• Process of transferring blood or blood-based
products from one person to the circulatory system of
another
• Life-saving especially to people who suffer
excessive blood loss due to trauma or surgery
• Compatibility of blood types:
    Individual with blood type   Can accept blood of type
                A                         A, O
                B                         B, O
               AB                      A, B, AB, O
       (Universal recipient)
               O                            O
        (Universal donor)

1E1N transport in humans 2012

  • 1.
  • 2.
    learningOBJECTIVES Atthe end of the lesson, you should be able to: - Explain why multi-cellular organisms such as human beings and plants need a transport system. - Describe the parts of the human transport system – heart, vessels, blood. - Describe the parts of the heart - atrium, ventricle. 4 main vessels from and to the heart. - Describe the different components of blood and their functions. - Explain how blood acts as a transport medium. - Explain how diffusion and osmosis are involved in the transport system. - Describe double circulation.
  • 3.
    funFACT It would takeabout 1,200,000 mosquito bites to completely drain the average human of blood. (Discover magazine, August 2007)
  • 4.
    whyTRANSPORT? If you staywithin 500 m – 1 km of the school, you probably would not mind walking to school…
  • 5.
  • 6.
    whyTRANSPORT? BUT if youstayed at Bedok, Woodlands, or even Boon Lay… You would probably take a form of public transport. (or go to a school within walking distance…) WHY?
  • 7.
  • 8.
    whyTRANSPORT? Likewise, in unicellularorganisms, The cell is in direct contact with the external environment. Diffusion alone is enough to: - transport essential materials such as oxygen and nutrients to the cell - remove waste such as carbon dioxide rapidly
  • 9.
  • 10.
    whyTRANSPORT? In multicellular (complex)organisms, Cells are far from the external environment. Diffusion alone is too slow to: - transport essential materials such as food to the various organs - remove waste products efficiently
  • 11.
    whyTRANSPORT? Thus, a transportsystem is developed to move these substances  eg. Blood system in humans This will ensure - a continual supply of nutrients, oxygen and other useful materials for metabolism - the removal of toxic waste products produced by metabolism
  • 12.
    circulatorySYSTEM The human circulatory systemconsists of three parts: heart • heart (pumps blood blood around the body) vessels • blood (liquid which blood carries materials) • blood vessels (tubes which carry blood around the body)
  • 13.
    theHEART left atrium right atrium left ventricle right ventricle
  • 14.
  • 15.
    theHEART • pumps bloodaround the body • all mammals have hearts that are similar in structure • human heart is about the size of our fists • made up of cardiac muscles • comprises 4 chambers  2 upper chambers called atria (left and right)  2 lower chambers called ventricles (left and right)
  • 16.
    theHEART • right sideof heart pumps blood to lungs only (which are a short distance from the heart) • left side of heart pumps blood around the body (which are further away from the heart) • hence left ventricle has thicker muscular walls than the right ventricle
  • 17.
    theHEART The blood is then De-oxygenated pumped from the This blood passes blood from the body ventricle out of left Oxygenated blood from the right enters the right atrium heart to the restthe lungs enter from ventricle the out into then and then into the the left atrium and the lungsthe body of right ventricle flow into the left ventricle Right atrium Left atrium Left ventricle Right ventricle
  • 18.
    theHEART This blood passes The blood is then from the right pumped from the ventricle then out into left ventricle out of the lungs the heart to the rest of the body De-oxygenated Oxygenated blood blood from the body from the lungs enter enters the right atrium the left atrium and and then into the flow into the left right ventricle ventricle Right atrium Left atrium Left ventricle Right ventricle
  • 19.
    bloodCIRCULATION • In mammals,blood flows through the heart twice in one complete circuit. This is known as double circulation.
  • 20.
    bloodCIRCULATION From the heart to the lungs and back to the heart, • In the lungs, the blood collects oxygen and releases carbon dioxide. • Blood that returns to the heart is now rich in oxygen, called oxygenated blood.
  • 21.
    bloodCIRCULATION From the heart to the rest of the body and back to the heart, • As blood passes the small intestine, it collects digested food. • The blood supplies all the cells of the body with this digested food together with oxygen picked up in the lungs. • After oxygen is deposited in body tissues, the blood now has little oxygen, called deoxygenated blood.
  • 22.
  • 23.
    circulatorySYSTEM The human circulatory systemconsists of three parts: heart • heart (pumps blood blood around the body) vessels • blood (liquid which blood carries materials) • blood vessels (tubes which carry blood around the body)
  • 24.
  • 25.
    BLOOD Has two main functions:  To carry materials round the body. These materials include nutrients, oxygen, carbon dioxide and other waste substances.  To protect us against diseases. BLOOD plasma red blood cells white blood cells platelets
  • 26.
    bloodCOMPONENTS BLOOD red blood cells white blood cells Platelets plasma (erythrocytes) (leukocytes) (thrombocytes) PLASMA •Pale yellowish liquid •Contains mainly water (90%) •Contains mainly dissolved substances  like nutrients (digested food), hormones, antibodies and waste products (carbon dioxide and urea).
  • 27.
    bloodCOMPONENTS BLOOD red blood cells white blood cells Platelets plasma (erythrocytes) (leukocytes) (thrombocytes) •Contains haemoglobin  gives RBC red colour when combined with oxygen; or purplish colour when combined with carbon dioxide  combines reversibly with oxygen so RBC can transport oxygen around the body
  • 28.
    bloodCOMPONENTS BLOOD red blood cells white blood cells Platelets plasma (erythrocytes) (leukocytes) (thrombocytes) •Does not contain nuclei  More space to contain haemoglobin for oxygen transport
  • 29.
    bloodCOMPONENTS BLOOD red blood cells white blood cells Platelets plasma (erythrocytes) (leukocytes) (thrombocytes) WHITE BLOOD CELLS
  • 30.
    bloodCOMPONENTS BLOOD red blood cells white blood cells Platelets plasma (erythrocytes) (leukocytes) (thrombocytes) WHITE BLOOD CELLS •Much bigger in size than RBC •Fewer in number than RBC •Colourless (no haemoglobin) •Contains a nucleus
  • 31.
    bloodCOMPONENTS BLOOD red blood cells white blood cells Platelets plasma (erythrocytes) (leukocytes) (thrombocytes) WHITE BLOOD CELLS •Two types:  Phagocytes  Ingests foreign particles by phagocytosis  Lymphocytes  Produces antibodies that neutralise bacteria and viruses
  • 32.
    bloodCOMPONENTS BLOOD red blood cells white blood cells Platelets plasma (erythrocytes) (leukocytes) (thrombocytes) PLATELETS •Cell fragments (not complete cells) •No nucleus •Involved in the process of blood clotting
  • 33.
    circulatorySYSTEM The human circulatory systemconsists of three heart parts: blood • blood vessels • heart blood • blood vessels
  • 34.
    bloodVESSELS • The bloodvessels are a network of tubes to carry blood around the body. • Namely the artery, vein & capillary
  • 35.
    bloodVESSELS - summary Artery Vein Capillary Structure Thick, elastic, Thinner, less One-cell thick muscular walls elastic, less endothelium muscular walls Functions Transports Transports Transports blood away blood towards nutrients & from the heart the heart waste materials Blood High blood Lowest blood Low blood pressure from pressure pressure Pressure heart
  • 36.
    bloodDISORDERS Condition/ Description Possible causes Treatment Disease Haemophilia Genetic illnesses that Lack of one of the No cure, controlled affect the ability of clotting factors by regular injection of blood to clot caused by a deficient the deficient clotting gene factor Anaemia Deficiency of red Excessive blood loss, Iron supplement, blood cells or deficient blood cell increased intake of haemoglobin production (such as food rich in iron, due to deficient iron blood transfusion intake) Leukaemia Cancer of the blood Exposure to Chemotherapy, bone or bone marrow radiation, certain marrow transplant characterised by chemicals or viruses, excessive production genetic of usually white blood predisposition cells
  • 37.
    heartDISEASES Disease Description Possible causes Treatment Heart attack Occurs when blood supply to a Blood clot in heart Ensure oxygen intake, part of the heart is interrupted arteries bypass surgery, leading to damage or death of Increased risk factor: medications heart tissue smoking, excessive alcohol consumption, abuse of drugs, high cholesterol, hypertension, diabetes, heart diseases Stroke Rapid loss of brain function due Blood clot, Medications, ensure to interruption of blood supply to haemorrhage (share oxygen intake, surgery all or part of the brain some of the risk factors as heart attack)
  • 38.
    bloodTRANSFUSION • Process oftransferring blood or blood-based products from one person to the circulatory system of another • Life-saving especially to people who suffer excessive blood loss due to trauma or surgery • Compatibility of blood types: Individual with blood type Can accept blood of type A A, O B B, O AB A, B, AB, O (Universal recipient) O O (Universal donor)