The circulatory system consists of the heart, blood vessels, and blood. The heart pumps blood through two circuits - pulmonary circulation to the lungs and systemic circulation to the rest of the body. Blood flows from the right side of the heart to the lungs to receive oxygen, then to the left side to pump oxygenated blood to all body tissues through arteries and returning deoxygenated blood back to the heart through veins. The circulatory system transports oxygen, nutrients, hormones, and wastes throughout the body.
The Human Blood Circulatory system
Humans and other vertebrates have a closed blood circulatory system:
This system consists of
the heart (pump),
series of blood vessels
the blood that flows through them.
This means that circulating blood is pumped through a system of vessels.
Functions of Human Blood Circulatory System
1. oxygen
2. carbon dioxide
3 nutrients
4. water
5. ions
6. hormones
7. antibodies
8. metabolic wastes
The Human Blood Circulatory system
Humans and other vertebrates have a closed blood circulatory system:
This system consists of
the heart (pump),
series of blood vessels
the blood that flows through them.
This means that circulating blood is pumped through a system of vessels.
Functions of Human Blood Circulatory System
1. oxygen
2. carbon dioxide
3 nutrients
4. water
5. ions
6. hormones
7. antibodies
8. metabolic wastes
Blood is carried through the body via blood vessels. An artery is a blood vessel that carries blood away from the heart, where it branches into ever-smaller vessels.
Definition
Location of heart
Function of heart
Different layers of heart
Functions of different layers of heart
Chambers of heart
Valves of heart
Functions of the valves of the heart
Blood flow and cardiac cycle of heart
conducting system of heart
An 8th grade lesson introductory lesson on the circulatory system ... in addition to the powerpoint I had the students take their pulse at rest at the beginning of class and then again during the middle of class after having them run in place for 30 seconds
Blood vessels: Arteries, Veins and CapillariesAmir Rifaat
It is one of the circulatory systems. This explains the roles of arteries, veins and capillaries. It also differentiate between the arteries, veins and capillaries. This slide also explained the pulmonary circuit and systemic curcuit. This is an interesting notes and easy to be understand.
In this course you will learn the cardiovascular system is Responsible for transporting oxygen, nutrients, hormones, and cellular waste products throughout the body, the cardiovascular system is powered by the body's hardest-working organ — the heart, which is only about the size of a closed fist.
Blood is carried through the body via blood vessels. An artery is a blood vessel that carries blood away from the heart, where it branches into ever-smaller vessels.
Definition
Location of heart
Function of heart
Different layers of heart
Functions of different layers of heart
Chambers of heart
Valves of heart
Functions of the valves of the heart
Blood flow and cardiac cycle of heart
conducting system of heart
An 8th grade lesson introductory lesson on the circulatory system ... in addition to the powerpoint I had the students take their pulse at rest at the beginning of class and then again during the middle of class after having them run in place for 30 seconds
Blood vessels: Arteries, Veins and CapillariesAmir Rifaat
It is one of the circulatory systems. This explains the roles of arteries, veins and capillaries. It also differentiate between the arteries, veins and capillaries. This slide also explained the pulmonary circuit and systemic curcuit. This is an interesting notes and easy to be understand.
In this course you will learn the cardiovascular system is Responsible for transporting oxygen, nutrients, hormones, and cellular waste products throughout the body, the cardiovascular system is powered by the body's hardest-working organ — the heart, which is only about the size of a closed fist.
This comprehensive PowerPoint presentation delves into the intricate details of the cardiovascular system. It is designed to engage students from 9th grade through to graduation, making it an invaluable resource for learners at various levels.
The cardiovascular system The cardiovascular system is essential for overall health.
You can take steps to improve your cardiovascular health.
Talk to your doctor about your heart health.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
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Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
2. The Circulatory System
• Consists of organs and tissues that transport
essential materials to body cells and remove their
waste products.
• This body system is also known as the
CARDIOVASCULAR SYSTEM.
3. FUNCTIONS
Transport nutrients, hormones
Remove waste products
Gaseous exchange
Immunity
Blood vessels transport blood
◦ Carries oxygen and carbon dioxide
◦ Also carries nutrients and wastes
Heart pumps blood through blood vessels
4. How the Circulatory System Works
• Hormones from glands
help regulate cell activity.
• Oxygen from the lungs
combines with nutrients
to provide energy.
• Nutrients provided by
food gives energy to cells.
5. Blood Vessels -A network of tubes
–Arteriesarterioles move away from the heart
•Elastic Fibers
•Circular Smooth Muscle
–Capillaries – where gas exchange takes place.
•One cell thick
•Serves the Respiratory System
–VeinsVenules moves towards the heart
•Skeletal Muscles contract to force blood back
from legs
•One way values
6. ARTERIES
Blood vessels that
carry blood away from
the heart are called
arteries.
They are the thickest
blood vessels and they
carry blood high in
oxygen known as
oxygenated blood
(oxygen rich blood).
8. CLASSIFICATION OF ARTERIES
• Elastic- e.g. (Aorta & its Major branches)
• Muscular -e.g.(Renal, Testicular, Radial, Tibial
etc.)
9. CAPILLARIES (5-8 micron)
• The smallest blood
vessels are
capillaries and they
connect the arteries
and veins.
• This is where the
exchange of
nutrients and gases
occurs.
10. BODY CONTAINS TWO KINDS OF CAPILLARIES
• CONTINUOUS-
• SKIN, LUNG, SMOOTH MUSCLE, CONNECTIVE
TISSUES
• FENESTRATED-
• PANCREAS,ENDOCRINE GLANDS, SMALL
INTESTINE, etc.
11. VEINS
• Blood vessels that carry
blood back to the heart
are called veins.
• They have one-way
valves which prevent
blood from flowing
backwards.
• They carry blood that is
high in carbon dioxide
known as deoxygenated
blood (oxygen poor
blood).
12. VEINS
• Thin Walled
• Large irregular lumen
• Have valves
• Types:
Large
Medium
Small
13. How the Circulatory System Works
• Germ fighters (antibodies)
from different parts of the
body help to fight infection
and disease.
• Wastes are carried to the liver
and kidneys for removal from
the body.
• Carbon Dioxide, a waste gas,
is carried away and delivered
to the lungs, which remove it
from the body.
14. Parts of the Circulatory System
• Heart: heart pumps
blood through two
major pathways.
• Blood Vessels
• Blood
• Pulmonary Circulation:
flow blood from the
heart to the lungs and
back to the heart.
• Systemic Circulation: is
the flow of blood to all
the body tissues except
the lungs.
15. CIRCULATION
–Coronary circulation – the circulation
of blood within the heart.
–Pulmonary circulation – the flow of
blood between the heart and lungs.
–Systemic circulation – the flow of
blood between the heart and the cells
of the body.
16. SYSTEMIC AND PULMONARY CIRCULATION
Pulmonary circulation
The flow of blood
between the heart
and lungs.
Systemic circulation
The flow of blood
between the heart
and the cells of the
body.
Chapter 18, Cardiovascular
System
16
Figure 18.5
18. The Heart
Consists of four chambers in which blood flows.
• Blood enters the R atrium and
passes through the right
ventricle.
• The R ventricle pumps the blood
to the lungs where it becomes
oxygenated.
• The oxygenated blood is brought
back to the heart by the
pulmonary veins which enter
the L atrium.
• From the L atrium blood flows to
the L ventricle.
• The L ventricle pumps blood to
the aorta which distributes the
oxygenated blood throughout
the rest of the body.
19. Blood enters the R
atrium and passes
through the right
ventricle.
The R ventricle pumps
the blood to the lungs
where it becomes
oxygenated.
The oxygenated blood is
brought back to the
heart by the pulmonary
veins which enter the L
atrium.
From the L atrium blood
flows to the L ventricle.
The L ventricle pumps
blood to the aorta which
distributes the
oxygenated blood
throughout the rest of
the body.
20. Pathway of the blood
•Superior Vena Cava
•Right Atrium
•Right Ventricle
•Lungs
•Pulmonary Vein
•Left auricle
•Bicuspid Valve
•Left Ventricle
•Aorta
•To the bodies organs & cells
24. • heart is an amazing organ. It continuously pumps
oxygen and nutrient-rich blood throughout body to
sustain life.
• This fist-sized powerhouse beats (expands and
contracts) 100,000 times per day, pumping five or six
quarts of blood each minute, or about 2,000 gallons
per day
• The heart beats 2.5 billion times in a lifetime. The 5
quarts of blood an adult male continually pumps (4
quarts for women) flow at an average speed of 3 to 4
mph — walking speed. That's fast enough so that a
drug injected into an arm reaches the brain in only a
few seconds.
25. SUMMARY
• Blood flows through heart and lungs in four steps:
• The right atrium receives oxygen-poor blood from
the body and pumps it to the right
ventricle through the tricuspid valve. ... The left
atrium receives oxygen-rich blood from the lungs
and pumps it to the left ventricle through the mitral
valve.
27. Blood: a mixture of solids in a large amount
of liquid called plasma.
• Plasma: is about 92%
water. It transports
blood solids, nutrients,
hormones, and other
materials.
• Red Blood Cells: carry
oxygen to cells and
carbon dioxide away
from them.
28. Blood: a mixture of solids in a large amount
of liquid called plasma.
• White Blood Cells: help
fight disease and
infection by attacking
germs that enter the
body.
• Platelets: help blood
form a clot at the site of
a wound. A clot seals a
cut and prevents
excessive blood loss.
29. Blood Pressure
As blood is moved through body, it exerts pressure against the walls of blood
vessels.
• Systolic Pressure: as
heart contracts to push
blood into arteries,
blood pressure is at its
highest point.
• Diastolic Pressure: As
heart relaxes to refill,
blood pressure is at its
lowest point.
30. Problems of the Circulatory System
• Hypertension: is a condition in which blood
pressure is consistently higher than normal,
which can lead to heart attack, stroke, or
kidney failure.
• Stroke usually results from blood clots that
block vessels in the brain, or from the rupture
of a blood vessel.
• Heart Attack is a blockage of the flow of blood
to the heart.
31. Problems of the Circulatory System
• Anemia is an abnormally low level of
hemoglobin, a protein that binds to oxygen in
red blood cells.
• Leukemia is a disease in which extra white
blood cells are produced.
• Hemophilia is a disease in which the blood
plasma does not contain substances that help
the blood to clot.
32. Care of the Circulatory System
• Limit fat in your foods.
• Get regular physical
activity.
• Avoid tobacco.
• Aviod stress.