Dear all,
This ppt contains the cause, types, clinical and radiological features, treatment and complication of Knee ligament injury and meniscus injury. I hope this is useful to you.
Thank you
Functional Movement Screens for the Tennis ProfessionalEsserHealth
Functional Movement screens are an outstanding way to evaluate athletes for injury and for injury risk. Here is a recent presentation for tennis professionals on basic functional movement injury screens.
Reconstrução do Ligamento Cruzado Anterior com técnica All-inside - Graftlink...David Sadigursky
Aula a respeito da reconstrução do Ligamento Cruzado Anterior pela técnica All-inside com implantes da Arthrex® - Graftlink.
Enxerto: T. semitendíneo quadruplo
Fixação: TightRope
Guias: FlipCutter
David Sadigursky MD MSc
Total Hip replacement for Ankylosing Spondylitis: Planning & Execution Vaibhav Bagaria
Performing Total Hip replacement in Ankylosing Spondylitis requires a well thought of strategy. Preoperative planning, Inventory ordering, positioning, cup and stem orientation all play a role.
Rotator cuff Repair - New Techniques and ChallengesShoulderPain
This presentation reviews the current challenges and advances in state of the art rotator cuff repair. Learn more at https://www.theshouldercenter.com/
Dear all,
This ppt contains the cause, types, clinical and radiological features, treatment and complication of condylar fracture of femur and patella fracture. I hope this is useful to you.
Thank you
Functional Movement Screens for the Tennis ProfessionalEsserHealth
Functional Movement screens are an outstanding way to evaluate athletes for injury and for injury risk. Here is a recent presentation for tennis professionals on basic functional movement injury screens.
Reconstrução do Ligamento Cruzado Anterior com técnica All-inside - Graftlink...David Sadigursky
Aula a respeito da reconstrução do Ligamento Cruzado Anterior pela técnica All-inside com implantes da Arthrex® - Graftlink.
Enxerto: T. semitendíneo quadruplo
Fixação: TightRope
Guias: FlipCutter
David Sadigursky MD MSc
Total Hip replacement for Ankylosing Spondylitis: Planning & Execution Vaibhav Bagaria
Performing Total Hip replacement in Ankylosing Spondylitis requires a well thought of strategy. Preoperative planning, Inventory ordering, positioning, cup and stem orientation all play a role.
Rotator cuff Repair - New Techniques and ChallengesShoulderPain
This presentation reviews the current challenges and advances in state of the art rotator cuff repair. Learn more at https://www.theshouldercenter.com/
Dear all,
This ppt contains the cause, types, clinical and radiological features, treatment and complication of condylar fracture of femur and patella fracture. I hope this is useful to you.
Thank you
Objectives:
-Recognize the anatomy of the proximal tibia
-Describe initial evaluation and management
-Identify common fracture patterns
-Apply treatment principles and strategies for Partial articular fractures and Complete articular fractures
-Discuss rehabilitation and complications
-Learn Management in selected tibial plateau case scenarios
Dear all,
This ppt contains the cause, types, clinical and radiological features, treatment and complication of fracture of lateral condyle of the humerus, medial epicondyle of Humerus, and intercondylar fracture of Humerus. I hope this is useful to you.
Thank you
Dear all,
This ppt contains the cause, types, clinical and radiological features, treatment and complication of Colles' fracture, Barton's fracture and Smith's fracture. I hope this is useful to you.
Thank you
Dear all,
This ppt contains the cause, types, clinical and radiological features, treatment and complication of Femur shaft fracture. I hope this is useful to you.
Thank you
Dear all,
This ppt contains the cause, types, clinical and radiological features, treatment and complication of Inter-trochanteric fracture. I hope this is useful to you.
Thank you
Dear all,
This ppt contains the cause, types, clinical and radiological features, treatment and complication of dislocation of the Hip. I hope this is useful to you.
Thank you
Dear all,
This ppt contains the cause, clinical and radiological features, treatment and complication of fracture of the clavicle. I hope this is useful to you.
Thank you
Dear all,
This ppt contains the cause, types, clinical and radiological features, treatment and complication of dislocation of the shoulder. I hope this is useful to you.
Thank you
Dear all,
This ppt contains the cause, types, clinical and radiological features, treatment and complication of Scaphoid fracture, Benett's fracture, Rolando's fracture, Mallet's finger, Metacarpals fracture and Phalanges fracture. I hope this is useful to you.
Thank you
Dear all,
This ppt contains the cause, types, clinical and radiological features, treatment and complication of forearm bone fractures, Monteggia and Galeazzi fracture. I hope this is useful to you.
Thank you
Dear all,
This ppt contains the cause, types, clinical and radiological features, treatment and complication of dislocation of the elbow and fracture of the capitulum, the neck of radius, and head of radius. I hope this is useful to you.
Thank you
Dear all,
This ppt contains the cause, types, clinical and radiological features, treatment and complication of supra Condylar fracture of Humerus. I hope this is useful to you.
Thank you
Dear all,
This ppt contains the cause, types, clinical and radiological features, treatment and complication of fracture of shaft of Humerus. I hope this is useful to you.
Thank you
Dear all,
This ppt contains the cause, types, clinical and radiological features, treatment and complication of fracture of Greater Tuberosity and Surgical neck of Humerus. I hope this is useful to you.
Thank you
Dear all,
This ppt includes the acute and chronic effect of exercise on different body system which includes musculoskeletal systems, cardiovascular systems, respiratory system, endocrive system, psychological effects etc. I hope this is helpful for you.
Thank you
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
Email / Skype : kefaya1771@gmail.com
Threema: PXHY5PDH
New BATCH Ku !!! MUCH IN DEMAND FAST SALE EVERY BATCH HAPPY GOOD EFFECT BIG BATCH !
Contact me on Threema or skype to start big business!!
Hot-sale products:
NEW HOT EUTYLONE WHITE CRYSTAL!!
5cl-adba precursor (semi finished )
5cl-adba raw materials
ADBB precursor (semi finished )
ADBB raw materials
APVP powder
5fadb/4f-adb
Jwh018 / Jwh210
Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Surgical Site Infections, pathophysiology, and prevention.pptx
15. Knee ligament injury
1. By :- Dr. Bindesh D. Patel, PT
Deputy Registrar
P P Savani University
Ligament injuries
2. Mechanism
• Injured by mostly twisting or bending force
• MCL
– Valgus force. Abduction of leg on femur
• LCL
– Varus force. Adduction of leg on femur
– Avulsion fracture may occur
– Less common
3. • ACL
– Associated with MCL or LCL
– Twisting force on a semi flexed knee
– O’Donoghue triad
6. Diagnosis
• Pain and swelling
• History of fall, injury followed by sound of
something tearing
• Haemarthrosis
• MCL, LCL – Localized pain on medial, lateral
side
• ACL, PCL – Vague pain in knee
7. • Tests
– MCL tear test
– LCL tear test
– Anterior Drawer test
– Posterior Drawer test
8. • Radiological examination
• X-ray will be helpful in avulsion fracture. “No
bone fracture” in case of haemarthrosis
• MRI more helpful in diagnosis
• Arthroscopic examination may be done
9. Treatment
• Conservative method
• For Grade I, II injury
• Haematoma aspiration
• Once swelling subsides Physiotherapy will be
helpful
10. • Operative methods
• Indicated in grade III and in case of multiple
ligament injury
• Surgery after 2-3 week, once pain subsides
• Repair of ligament
– Done in case of fresh ligament injury
11. • Reconstruction
– Done in case of case presented late when knee
instability is there
– Ligament is reconstructed using patient’s tendon
and fascia
– Allograft or synthetic ligament has also been used
15. By :- Dr. Bindesh D. Patel, PT
Deputy Registrar
P P Savani University
Meniscal injuries
16. Mechanism
• Semi flexed knee and twisting
• May occur while walking on uneven surface
• Meniscus may be stuck in and nipped as
rotation occurs
• Medial meniscus injury is common as it is less
mobile
17. Pathoanatomy
• Menisucs is torn most commonly at posterior
horn
• Meniscus is avascular structure
• It left untreated undergoes subtears and can
damage articular surface
19. Clinical features
• Young male actively engaged in sports
• Recurrent episodes of pain and locking of
knee
• Patient may complaint of a sudden jerk while
walking or something flicking over inside the
joint
• Swelling, appears after few hours and lasting
for few days
20. • History of twisting injury followed by swelling
overnight
• Knee remains in 10 degree knee flexion.
Complete extension is difficult
• Mcmurray’s test
• Apley’s test
22. Treatment
• Acute meniscal tear
– If Knee is locked, it is manipulated under general
anesthesia. No special maneuver is needed.
– As knee relaxes, torn meniscus falls into place and
knee is unlocked
– Knee is immobilised for 2-3 weeks, followed by
Physiotherapy.
– Peripheral tear will heal.
23. • Chronic meniscal tear
– To excise the displaced fragment.
– Arthroscopic surgery is done
– Early return to work is possible
– Aim is to preserve the meniscus as much as
possible.
