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MALARIA
INTRODUCTION
MALARIA is a protozoal disease by
infection of plasmodium and
transmission to man by “
anopheline mosquito ” .
DEFINITION
MALXARIA IS A LIFE THREATING DISEASE
TRANSMITTED THROUGH THE BITE OF AN
INFECTED (ANOPHELES MOSQUITO)THEY
CARRY INFECTED PLASMODIUM PARASITE .
ANOTHER DEFINITION
•A DISEASE CAUSED BY A
PLASMODIUM PARASITE ,
TRANSMITTED BY BITE OF INFECTED
MOSQUITO AND SEVERITY DEPENDS
UPON THE SPECIES OF PLASMODIUM.
RISK
GROUPS• YOUNG CHILD
• NON IMMUNE
PREGNANT WOMEN
• PEOPLE WITH HIV
• IMMIGRANTS AND
INTERNATIONAL
TRAVELLERS
EPIDERMIOLOCICAL
DETERMINANTS
THIS IS VEDIO ON WHERE THE CASES
REPORTED MOST IN THE COUNTRY
AGENT FACTOR
MALARIA IS CAUSED BY 4 DIFFERENT
SPECIES OF PLASMODIUM .
• PLASMODIUM VIVAX
• PLAMODIUM FALCIPARUM
• PLASMODIUM MALARIA
• PLASMODIUM OVALE
• RESERVOIR OF INFECION
HUMAN IS ONE
WHO HARBOURS
THE SEXUAL
FORM BOTH THE
SEXES OF
GAMETOCYTE IN
BLOOD .
PERIOD OF
COMMUNICABILITY
ITS COMMUNICABLE AS LONG AS
MATURE , VIABLE GAMETOCYTE
EXIST IN CIRCULATING BLOOD IN
SUFFICIENT DENSITY TO INFECT
VECTOR MOSQUITES
HOST FACTOR
• AGE , SEX , RACE .
• OCCUPATION, SOCO ECONOMIC STATUS
• POPULATION MOBILITY
• IMMUNITY , HUMAN HABITS
ENVIORNMENTAL
FACTOR
• SEASON
• TEMPERATURE
• RAILFALL
• HUMIDITY
• ALTITUDE
LIFE CYCLE
LIFE CYCLE OF
MALARIAL PARASITE
• MALARIAL PARASITE WHENAN INFECTED
FEMALE ANOPHELES BITES A PERSON AND
INJECTING PARASITE IN FORM OF
SPOROZOITES INTO BLOOD STREAM .
THE SPOROZOITES PASS QUICKLY
INTO THE HUMAN LIVER
THE SPOROZOITES MULTIPLY
ASEXUALLY IN THE LIVER CELLS
OVER THE NEXT 7 TO 10 DYS
IN THE FORM OF MEROZOITES ARE
RELEASED FROM THE LIVER CELLS IN
VESSELS , JOURNEY THROUGH THE
HEART ARRIVE LUNGS , WHERE THEY
SETTLE IN THE LUNGS CAPILLARIES
THEN VESSICLES DISINTEGRATE ,
FREEING THE MEROZOITES TO
ENTER THE BLOOD PHASE OF THEIR
DEVELOPMENT
SOME INFECTED BLOOD CELLS LEAVE THE CYCLE OF
ASEXUAL MULTIPLICATION , AND ENTER THE SEXUAL
FORMS OF PARASITE , CALLED GAMETOCYTES
CIRCULATE IN BLOOD STREAM.
WHEN MOSQUITO BITES AN INFECTED HUMAN , IT
INGEST GAMETOCYTES , WHICH DEVELOP INTO
MATURE SEX CELLS CALLED GAMATES
FERTALIZED FEMALE GAMETES
DEVELOP INTO MOVING OOKINITE
THAT BURROW THROUGH MIDGUT WALL
OF MOSQUITO AND FORM OOCYSTS .
INSIDE OOCYST THERE IS ACTIVE
SPOROZOITES DEVELOP . THEY
EVENTUALLY BURST AND RELEASE
SPOROZOITES INTO BODY CAVITY THAT
TRAVEL TO THE MOSQUITO SALIVARY
GLAND .
THE INFECTION CYCLE OF HUMAN
INFCTION BEGINS AGAIN WHEN
MOSQUITO BITE ANOTHER PERSON
THIS IS A VEDIO ON LIFE CYCLE OF
MALARIAL PARASITE
TYPES OF MALARIA
•PLASMODIUM FALCIPARUM
•PLASMODIUM MALARIAE
•PLASMODIUM VIVAX
•PLASMODIUM OVALE
•PLASMODIUM KNOWLESI
Plasmodium falciparum
It’s a unicellular protozoan
parasite of humans and the
deadliest species of
plasmodiumthat causes
malaria in humans .
It causes the most
dangerous form .
Plasmodium vivax
It’s a protozoal parasite and
human pathogen . This is
most frequently and widely
distributed cause of
recurring malaria.
Plasmodium malariae
Its relatively mild form of malaria . The undifferentiated
febrile presentation is indistinguishable from other
malarias . Deaths in this is mainly caused by end stage
renal disease
Plasmodium ovale
It’s a non falciparum malaria infection .
Indigenous malaria decreased over recent decades . Mixed
infections occur in area where more that one species is
epidemic . It has been given relatively little attension
compared to other species .
Plasmodium knowlesi
Is considered as a fifth pathogenic species , which is
mainly a simian malaria occurring in Southeast Asia ,
and human can be infected occasionally .
INCUBATION
PERIOD
CAUSES
• IF YOU HAVE BITTEN BY AN INFECTED
FEMALE ANOPHELES MOSQUITO.
• IF YOU RECEIVE INFECTED BLOOD FROM
A MALARIA PATIENT DURING BLOOD
TRANSFUSION .
• INFECTED MOTHER TO THE CHILD
DURING PREGNANCY .
SYMPTOMS
• SHAKING CHILLS (MODERATE TO SEVERE)
• HIGH FEVER
• HEADACHE
• NAUSEA / VOMITING
SYMPTOMS
•Non stop dry cough
•Profuse sweating
•Loose motion
DIAGNOSIS
• HISTORY TAKING
• PHYSICAL EXAMINATION
DIAGNOSIS
• BLOOD TEST
• LIVER FUNCTION TEST
DIAGNOSIS
• ULTRASOUND (FOR ENLARGED SPLEEN)
• KIDNEY FUNCTION TEST
TREATMENT
THE TREATMENT CHOOSEN BY UR DOCTOR
DEPENDS ON FOLLOWING :-
• TYPE OF MALARIA
• AREA YOU TRAVELED TO
• SEVERITY OF ILLNESS
• YOUR MEDICAL HISTORY
• WHETHER YOU ARE PREGNANT
PREVENTION
• SAFEGUARD YOURSELF AND YOUR FAMILY
AGAINST MOSQUITES
• CLEAR ANY SOURCES OF STAGNANT WATER
PREVENTION
• WEAR PANTS AND LONG SLEEVED CLOTHES
• AVOID DANGER PLACES FIELDS , FOREST ,
SWAMPS AS MOSQUITOES ARE NIGHT
BREEDERS
COMPLICATIONS• SWELLING OF BLOOD VESSELS
• ACCUMULATON OF FLUID IN LUNGS OR
PLUMONARY EDEMA
COMPLICATIONS
• JAUNDICE
• SHOCK (Sudden fall in B.P)
• HYPOGLYCEMIA
• KIDNEY FAILURE
• DEHYDRATION
MANAGEMENT
MEDICAL
MANAGEMENT
• COMBNATION OF
PYRIMETHAMIN AND
SULFADOXINE [FANSIDAR]
• MOSQUITO NET
• COMBINATION OF
QUINIDE OR
QUININE PLUS
DOXYCYCLINE .
• ARTESCINATE
• SUPPORTIVE TREAMENT
WITH IV FLUIDS
AND BLOOD
INVESTIGATION
NURSING
MANAGEMENT
A .MAINTAIN A CLEAR AIRWAY.
B .REMOVE STOMACH CONTENTS
USING NG TUBE.
C . MAINTAIN INPUT AND OUTPUT
CHART.
D . NOTE APPEARANCE OF
HEMOGLOBINURIA.
E . MONITOR VITALS .
F . CHECK {LOC}.
CONCLUSION
MALARIA IS CONSIDERED AS THE MOST WIDELY
OCCURING DISEASE AFFECTING HUMANS OF THE
WORLD WHICH GETS SPREAD BY THE BITE OF
FEMALE ANOPHELES MOSQUITO , , MALARIA KILLS
THOUSANDS OF PEOPLE UNNECESSARILY . WITH
IMMEDIATE AND CORRECT TREATMENT PEOPLE ARE
ABLE TO RECOVER FROM THIS DISEASE WITH NO
PROBLEM . ANY DELAY IN SYMPTOMS MUST BE
REPORTED .
SUMMARYIN THIS TOPIC “ MALARIA ” WE LEARNED ABOUT ITS
DEFINITION ,
RISK GROUPS ,
 EPIDEMIIOLOGIAL DETERMINANCE ,
CAUSES ,
 SYMPTOMS ,
PREVENTION ,
TREATMENT ABOUT MALARIA
Video to revise what is learnedbefore

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Malaria for medicoz...............