DR. WONG SEAK KHOON
(2 November 2011)
Present by: Soediqin
Akmal
 Abdomen
Abdomen is part of trunk that lies between the
thorax and pelvis.
It is divided into 9 parts by 2 vertical lin...
Epigastrium
Right
Hypochondriu
m
Left
Hypochondriu
m
Umbilic
al
Right Lumbar Left lumbar
Right iliac fossa Hypogastrium Le...
Stomach
Pancreas
Lt lobe of liver
Liver
Gallbladder
Spleen
Tail of pancreas
Fundus of
stomach
Coils of
small
instestine
Ri...
Stomach
DuodenumGallbladder Pancreas
Small
intestine
Caecum
Kidney Kidney
Caecum
Appendix
Transverse
colon
Bladder
Sigmoi
...
 Abdominal pain is pain that is felt in the
abdomen
 Acute abdomen refers to a sudden, severe
abdominal pain of unclear ...
1. Somatic pain:
- due to irritation of parietal peritoneum
- parietal peritoneum covers:
(a) anterior & posterior abd. wa...
- Nerve supply: derived from nerve supplying
muscles & skin of abdominal
wall (T5- L2)
*exception: central portion of diap...
- Response to irritation:
(i) reflex contraction of corresponding
segment of muscle guarding
(ii) hyperaesthesia of overly...
2. Visceral pain:
- due to irritation of visceral peritoneum
- visceral peritoneum covers partially/
completely the intra-...
- Sensitive only to tension
- Nature: dull, poorly localised, deep,
referred to overlying skin with
same embryological ori...
Causes of
Abdominal Pain
Surgical
Medical
Non-traumatic
Traumatic
Hemorrhage
Infarction/
Strangulation Obstruction
Perforation
Inflammation/
Infection
Non- traumatic
Abdominal Pain
Pathology Disease
Inflammation •Diverticulitis
•Salphingitis
•Acute Pancreatitis
•Acute appendicitis
•Acute cholecystitis
...
 The causes of generalized abdominal pain :
• Irritable bowel syndrome
• Recurrent adhesive obstruction
• Mesenterric car...
1. Mild attack:
◦ Fluid resuscitation and analgesia
◦ NBM meant to rest the pancreas
◦ Treat predisposing factors such as ...
2. Severe attack:
◦ Resuscitate
◦ Defined by Ranson’s or Glasgow criteria
◦ Admit to ICU immediately
◦ Fluid and electroly...
1. Pancreatic necrosis & pseudocyst
formation
2. Abscess formation
3. Haemorrhage
4. Thrombosis
5. Fistulae
6. Recurrent e...
 The stomach and duodenum.
1.The insulin test:
 Consist of an injection of insulin which produces hypoglycemia
 Stimula...
3. Barium meal:
 Radiographic investigation
 Patient swallows a suspension of radiopaque barium sulphate
 Principally u...
 Small intestine.
1.Barium meal follow through X-rays:
 Studied by thaking filmx of abdomen at intervals after a barium ...
2. Sigmoidoscopy:
 Necessary to examine the rectum and colon
 Proctitis,polyps and carcinomas may be seen.
 Particulary...
 The liver.
1.Ultrasound scan:
 Diagnosis of fluid-filled lesions such as cysts and abcesses
 Detecting intrahepatic bi...
 Gallbladder and bile ducts:
1.Percutaneous transhepatic cholangiography:
 Useful investigation in patients with jaundic...
 The pancreas.
1.Lundh test;
 Assessment of tryptic activity in pancreatic juice collected following duodenal
intubation...
Pain
1.Site-9 region
2.Onset: acute or recurrent or gradual
3.Character :
-colicky- comes and goes in waves and
indicates ...
5.Associated symptoms, e.g vomiting, diarrhoea,
painful micturition etc
6.Timing:
 since onset
 Episodic or continuous. ...
 Past medical history
 Ask especially about:
 Previous surgical procedures including peri-
and postoperative complicati...
 Drug history
 Think about drugs that can precipitate abdominal
diseases and remember to ask about over-the-counter
drug...
 Smoking
 Smokers are at risk of peptic ulceration,
oesophageal cancer, colorectal cancer.
Smoking may also have a detri...
 Urethral pain: variable in presentation ranging
from a tickling discomfort to a severe sharp pain
felt at the end of the...
 Bowel ischaemia: dull, severe, constant, right
upper quadrant/central abdominal pain
exacerbated by eating.
 Biliary pa...
1. Commenest abdominal emergency
(Lifetime incidence 6%)
2. Causes:
(a) Obstruction by faecolith or lesion in
caecum
(b) R...
Base of appendix: McBurney’s point
Initiation of inflammation
Acute inflammation of mucosa
Extension of inflammation across appendiceal wall
Involvement of s...
Necrotic glandular mucosa sloughs into lumen
Lumen distended with pus
End-artery (appendiceal artery) thrombosed
Appendix ...
Intense & extensive
walling-off rxn Inadequate
containment
Appendiceal
mass
Generalised
peritonitis
Appendiceal
abscess
1. Pain: -vague
- begin at central abdomen/
retrosternal
- poorly localised
- colicky
- assoc. with Nausea & Vomiting
- du...
2. Localising symptoms depends on anatomical
relations of inflammed appendix
e.g. inflammed retrocecal appendix:
- irritat...
1. General appearance:
- Facial flush
- Low-grade pyrexia
- Tachycardia
2. Abdomen:
(i) Inspection: - Mild abdominal diste...
(ii) Palpation: Rt iliac fossa:
- Guarding (indicator of tenderness
severity)
- Tenderness, Rebound tenderness
- +ve Rovsi...
1. abdominal pain <72 hours
2. Vomiting 1-3 times
3. Facial flush
4. Tenderness at Rt iliac fossa
5. Low-grade pyrexia
6. ...
 No need if it can be diagnosed through
history and physical examination
 AXR for confusing findings, may detect free
ga...
1. UTI
2. Mesenteric adenitis
3. Constipation
4. Gynaecological disorder
(ectopic pregnancy)
5. Acute pancreatitis
6. Dive...
 Medical
◦ Antibiotics
 Surgical
◦ Appendicectomy
 Abdominal wall incision ( Lanz/
Classic Gridiron incision)
 Dividin...
1. Perforation
2. Appendiceal mass (usually resolve in the
next 2-6 weeks)
- pyrexia - LOA
- malaise - dull on percussion
...
Aetiology :
- Gallstones (38%-60%)
- Ethanol (35%)
- Trauma (1.5%)
- Mumps
- Autoimmune (PAN)
- Scorpion venom
- Hyperlipi...
Duodenopancreatic reflux
Enterokinase reflux
Activate pancreatic proenzymes
Inflammation, arterioles thrombose, local infa...
1. Mild attack:
- Acute interstitial pancreatitis
2. Severe attack:
- Acute haemorrhagic pancreatitis
- Acute necrotising ...
1. epigastric pain:
- sudden onset
- radiate to back
- no relieving factor
- aggrevated by movement
- assoc. with - Nausea...
1. General appearance:
- in pain
- pale
- sweating
- dyspneic & cyanosed
(respiratory distress in severe
attack)
- jaundic...
2. Abdomen:
(i) Inspection:
- mild abdominal distension
- Grey Turner’s sign only in Acute
Haemorrhagic
- Cullen’s sign Pa...
- fullness in epigastrium (abscess,
pseudocyst)
(ii) Palpation:
- Tender
- Guarding
- Rebound tenderness
(iii) Percussion:...
(iv) Auscultation:
- Bowel sound present in first 24 hrs
- Bowel sound absent when
paralytic ileus develops
1. FBC (WBC ,RBC )
2. Plasma amylase (>1200 IU/mL), (rises
within 12 hrs, return to normal in next 48-
72 hrs)
3. Plasma l...
6. Plain CXR (free gas under diaphragm)
7. Plain AXR (no psoas shadow
>>retroperitoneal fluid)
8. Ultrasound
9. CT scan to...
1.Scoring system by Ranson
2.Glasgow Criteria by Imrie
A. At admission or
diagnosis
B. During initial 48 hrs
1. Age >55 years (70yrs in
gall stone disease)
1. Hematocrit fall >1...
 A - Age > 55
 P - PO2 < 8 kPa (60mmHg) n=10.6
 N - Neutrophil count ( > 16 x 109 /L )
 C - Calcium < 2.0 mmol/L
 R -...
 clinical assessment, relief of pain and
resuscitation come before imaging tests
Hematology biochemistr
y
imaging
Blood tests
1.Haemoglobin
◦ -may be normal immediately after an acute bleed
◦ -low haemoglobin concentration may represent...
1.C-reactive protein
◦ -non-specific indicator of inflammatory activation
◦ -confirms organic illness if substantially ele...
4.Glucose-for diabetics or those with glycosuria
(beware of hyperglycaemia due to acute stress or
steroid therapy)
5.Liver...
1.Plain radiography
1.Erect chest X-ray
◦ -cardiovascular disease or abnormality, e.g.
cardiomegaly, thoracic aneurysm, ao...
2.Supine abdominal X-ray (erect or decubitus if
necessary)
◦ -bowel (gas pattern and dilatation, fluid levels, gas
in the ...
2.Ultrasound
 Gallstones
 Pelvic abnormalities in obstetric and gynaecological practice
 'Chronic' enlargement of the s...
4. CT scanning
 rapid, cost-effective evaluation of acute abdominal pain
Assessment of abdominal trauma-severity and grad...
 Duodenal ulcer:
• Surgery (ulcer is sutured or plugged using an
omentum patch)
• Supportive treatment with nasogastric s...
 Acute cholecystitis
 1st line treatment (medical) :
Fasting, intravenous fluid, analgesic
Start IV antibiotics (if pt h...
Laparoscopic Cholecystectomy
 Optimal management
contraindications advantages disadvantages
(i) Uncorrectable
Coagulopath...
 Pain after cholecystectomy
(I) retained or recurrent stone
(ii) iatrogenic biliary leak
(iii) stricture of CBD
(iv) papi...
 Other treatment modalities :
(I) Oral bile acid treatment
- monotherapy or combine therapy (6-12 months)
- ursodeoxychol...
Criteria for non surgical treatment of
gallstones:
 Cholesterol stones (<20mm in diameter)
 Fewer than 4 stones
 Functi...
MILD ATTACK
 Hourly pulse, BP, urine output
 Fluid resuscitation to replace fluid loss from profuse vomiting
 Analgesic...
SEVERE ATTACK
 Admit to ICU for close monitoring and early Rx of complications
 Evaluated every 48 hours.
 May die earl...
 Medical
◦ Antibiotics
 Surgical
◦ Appendicectomy
 Gridiron / Lanz skin incision
 Abdominal wall incision
 Dividing t...
abdominal pain
abdominal pain
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abdominal pain

  1. 1. DR. WONG SEAK KHOON (2 November 2011) Present by: Soediqin Akmal
  2. 2.  Abdomen Abdomen is part of trunk that lies between the thorax and pelvis. It is divided into 9 parts by 2 vertical lines, right and left midclavicular lines and also 2 horizontal lines, subcostal and intertubercular lines.
  3. 3. Epigastrium Right Hypochondriu m Left Hypochondriu m Umbilic al Right Lumbar Left lumbar Right iliac fossa Hypogastrium Left iliac fossa
  4. 4. Stomach Pancreas Lt lobe of liver Liver Gallbladder Spleen Tail of pancreas Fundus of stomach Coils of small instestine Right kidney Ascending colon Left kidney Descending colon Caecum Appendix Urinary bladder Sigmoi d colon
  5. 5. Stomach DuodenumGallbladder Pancreas Small intestine Caecum Kidney Kidney Caecum Appendix Transverse colon Bladder Sigmoi d colon
  6. 6.  Abdominal pain is pain that is felt in the abdomen  Acute abdomen refers to a sudden, severe abdominal pain of unclear etiology that is less than a week in duration ◦ eg. acute peritonitis, acute pancreatitis, acute cholecystitis, acute cholangitis, acute appendicitis diabetic ketoacidosis
  7. 7. 1. Somatic pain: - due to irritation of parietal peritoneum - parietal peritoneum covers: (a) anterior & posterior abd. wall (b) undersurface of diaphgram (c) pelvic cavity
  8. 8. - Nerve supply: derived from nerve supplying muscles & skin of abdominal wall (T5- L2) *exception: central portion of diaphrgam (phrenic nerve: C3,C4,C5) - Sensitive to: mechanical thermal chemical
  9. 9. - Response to irritation: (i) reflex contraction of corresponding segment of muscle guarding (ii) hyperaesthesia of overlying skin - Nature: sharp, localised, knife-like
  10. 10. 2. Visceral pain: - due to irritation of visceral peritoneum - visceral peritoneum covers partially/ completely the intra-abdominal viscera - pain is mediated through sympathetic branches of autonomic system, to thoracic (T6-T12) & lumbar (L1,L2) segment of spinal cord
  11. 11. - Sensitive only to tension - Nature: dull, poorly localised, deep, referred to overlying skin with same embryological origin
  12. 12. Causes of Abdominal Pain Surgical Medical Non-traumatic Traumatic
  13. 13. Hemorrhage Infarction/ Strangulation Obstruction Perforation Inflammation/ Infection Non- traumatic Abdominal Pain
  14. 14. Pathology Disease Inflammation •Diverticulitis •Salphingitis •Acute Pancreatitis •Acute appendicitis •Acute cholecystitis Obstruction •Ureteric obstruction •Urinary retention •Intestinal obstruction •Biliary obstruction Ischaemia •Strangulated hernia •volvulus •Torsion of ovarian cyst Perforation •Perforated peptic ulcer •Perforated cancer •Biliary peritonitis Rupture •Ruptured ectopic pregnancy •Ruptured aneurysm
  15. 15.  The causes of generalized abdominal pain : • Irritable bowel syndrome • Recurrent adhesive obstruction • Mesenterric carcinoma • Carcinomatosis • Chronic constipation • Radiation damage • Reptriperitonial tumours • Endomettriosis • Pelvic-uriteric junction obstruction • Lumbar spine pain • Retroperitonial fibrosis • psychosomatic •
  16. 16. 1. Mild attack: ◦ Fluid resuscitation and analgesia ◦ NBM meant to rest the pancreas ◦ Treat predisposing factors such as gall stones ◦ Discouraged alcohol abuse ◦ NG tube to aspirate stomach content and prevent vomiting ◦ Prophylactic antibiotic i.e. imipenem and cephalosporin ◦ Daily measurement of plasma amylase – progression of ds ◦ LFT and renal profile
  17. 17. 2. Severe attack: ◦ Resuscitate ◦ Defined by Ranson’s or Glasgow criteria ◦ Admit to ICU immediately ◦ Fluid and electrolyte management ◦ Treat hypocalcaemia ◦ Ventilatory support 3. Surgery: - Abscess drainage - Cholecystectomy-if stone in gall bladder
  18. 18. 1. Pancreatic necrosis & pseudocyst formation 2. Abscess formation 3. Haemorrhage 4. Thrombosis 5. Fistulae 6. Recurrent edematous pancreatitis
  19. 19.  The stomach and duodenum. 1.The insulin test:  Consist of an injection of insulin which produces hypoglycemia  Stimulates the nucleus of vagus in the brain stem  Helpful when a patient develops a recurrent ulcer following vagotomy for duodenal ulceration.  The blood sugar has to fall below 45mg/100ml  Measure before and after insulin in injected by slow i.v infusion 2.Plain x-ray:  Patients lying in supine position  Suspected peritonitis due to perforation of gastric or duodenal ulcer  Gas maybe seen under the diaphragm  Usually on the right side
  20. 20. 3. Barium meal:  Radiographic investigation  Patient swallows a suspension of radiopaque barium sulphate  Principally use in the diagnosis of gastric and duodenal ulcer and gastric carcinoma.  Chronic gastric ulcer: seen as a projection from the wall or as a ronded deposit.  Duodenal ulcer:seen a face with a stellate appearance of the mucosal fold.  Pyloric stenosis: an increased amount of resting juice present and grossly enlarged stomach . 4.Endoscopy and biopsy:  Possible to see the whole of the oesophagus,stomach and duodenum  Biopsy forceps:to obtain specimens for histological and cytological examination.  Can differentiate benign from malignant lesions  Rapid diagnosis of upper gastrointestinal bleeding.
  21. 21.  Small intestine. 1.Barium meal follow through X-rays:  Studied by thaking filmx of abdomen at intervals after a barium meal.  Abnormalities in the transit time to the colon and in small bowel pattern such as dilatation,narrowing, fistula and mucosal abnormalities. 2. Biopsy:  Small intestine biopsy importance in diagnosis of the malabsorption syndrome where a flat mucosa is seen.  Colon ,rectum and anus. 1.Protoscopy:  Can see piles as reddish/blue swelling which bulge into the lumen  Can see internal opening of an anal fistula,an anal or low rectal polyp and chronic anal fissure
  22. 22. 2. Sigmoidoscopy:  Necessary to examine the rectum and colon  Proctitis,polyps and carcinomas may be seen.  Particulary useful in the differential diagnosis of diarrhoea of colonic region. 3. Barium enema:  Can see the obstruction of the colon,tumours,diverticular disease,fistulae and other abnormalities can be recognize. 4.Colonoscopy:  Inspect the whole colonis mucosa round to the caecum.  Polyps and diverticulitis can be seen.
  23. 23.  The liver. 1.Ultrasound scan:  Diagnosis of fluid-filled lesions such as cysts and abcesses  Detecting intrahepatic bile ducts. 2.Needle biopsy of liver:  Diagnosis for liver abcess 3. Liver function test:  To see the albumin,globulin,AST and ALT level.
  24. 24.  Gallbladder and bile ducts: 1.Percutaneous transhepatic cholangiography:  Useful investigation in patients with jaundice due to obstruction of the main bile ducts.  Investigations the site of the obstruction due to tumours of the head of the pancreas,iatrogenic and alignant bile ducts strictures –can be accurately localized and diffrentiated. 2.ERCP(endoscopic retrograde cholangiopancreatography)  Useful in the rapid diagnosis and localization of the different causes of jaundice due to obstruction of the main bile ducts.
  25. 25.  The pancreas. 1.Lundh test;  Assessment of tryptic activity in pancreatic juice collected following duodenal intubation  Indirect stimulation of the pancreas by prior ingestion of a meal.  Tryptic activity is less than 6 iu/litre. 2. Triple test.  Exocrine function.  Cytology  Hypotonic duodenography 3. ERCP
  26. 26. Pain 1.Site-9 region 2.Onset: acute or recurrent or gradual 3.Character : -colicky- comes and goes in waves and indicates obstruction of a hollow, muscular- walled organ (intestine, gallbladder, bile duct, ureter). -burning-an acid cause and is related to the stomach, duodenum or lower end of the oesophagus 4.Radiation: -Right scapula: gallbladder -Shoulder-tip: diaphragmatic irritation -Mid-back: pancreas.
  27. 27. 5.Associated symptoms, e.g vomiting, diarrhoea, painful micturition etc 6.Timing:  since onset  Episodic or continuous. If episodic, duration and frequency of attacks;  If continuous, any changes in the severity  Variation by day or night, during the week or month, e.g. relating to the menstrual cycle 7.exacerbation & relieving factor 8.Severity
  28. 28.  Past medical history  Ask especially about:  Previous surgical procedures including peri- and postoperative complications and anaesthetic complications.  Chronic bowel diseases (e.g. IBD including recent flare-ups and treatment to date).  Possible associated conditions (e.g. diabetes with haemachromatosis).
  29. 29.  Drug history  Think about drugs that can precipitate abdominal diseases and remember to ask about over-the-counter drugs. For example:  Hepatitis: halothane, phenytoin, chlorothiazides, pyrazinamide, isoniazid, methyl dopa, HMG CoA reductase inhibitors (statins, sodium valproate, amiodarone, antibiotics, NSAIDs.  Cholestasis: chlorpromazine, sulphonamides, sulphonylureas, rifampicin, nitrofurantoin, anabolic steroids, oral contraceptive pill.  Fatty liver: tetracycline, sodium valproate, amiodarone.  Acute liver necrosis: paracetamol.  Ask also about previous blood transfusions
  30. 30.  Smoking  Smokers are at risk of peptic ulceration, oesophageal cancer, colorectal cancer. Smoking may also have a detrimental outcome on the natural history of Crohn's disease.  Alcohol a detailed history is required.If dependence is suspected
  31. 31.  Urethral pain: variable in presentation ranging from a tickling discomfort to a severe sharp pain felt at the end of the urethra (tip of the penis in males) and exacerbated by micturition. Can be so severe that patients attempt to hold on to urine causing yet more problems!  Small bowel obstruction: colicky central pain associated with vomiting, abdominal distension & constipation.  Colonic pain: as above under small bowel but sometimes temporarily relieved by defaecation or passing flatus.
  32. 32.  Bowel ischaemia: dull, severe, constant, right upper quadrant/central abdominal pain exacerbated by eating.  Biliary pain: severe, constant, right upper quadrant/epigastric pain that can last hours and is often worse after eating fatty foods.  Pancreatic pain: epigastric, radiating to the back and partly relieved by sitting up and leaning forward.  Peptic ulcer pain: dull, burning pain in the epigastrium. Typically episodic at night, waking the patient from sleep. Exacerbated by eating and sometimes relieved by consuming
  33. 33. 1. Commenest abdominal emergency (Lifetime incidence 6%) 2. Causes: (a) Obstruction by faecolith or lesion in caecum (b) Recurrent inflammation (c) Enlargement of lymphoid follicles
  34. 34. Base of appendix: McBurney’s point
  35. 35. Initiation of inflammation Acute inflammation of mucosa Extension of inflammation across appendiceal wall Involvement of serosa by inflammation Visceral peritonitis (referred pain) Peritonitis spread to adjacent structure (localised pain)
  36. 36. Necrotic glandular mucosa sloughs into lumen Lumen distended with pus End-artery (appendiceal artery) thrombosed Appendix infarction Gangrenous appendix Perforation of appendix wall Attempt to wall off perforation by: omentum, adjacent bowel
  37. 37. Intense & extensive walling-off rxn Inadequate containment Appendiceal mass Generalised peritonitis Appendiceal abscess
  38. 38. 1. Pain: -vague - begin at central abdomen/ retrosternal - poorly localised - colicky - assoc. with Nausea & Vomiting - duration: few hours/ days - pain then shifted to Rt iliac fossa
  39. 39. 2. Localising symptoms depends on anatomical relations of inflammed appendix e.g. inflammed retrocecal appendix: - irritates psoas muscle>> involuntary Rt hip flexion, pain on extension
  40. 40. 1. General appearance: - Facial flush - Low-grade pyrexia - Tachycardia 2. Abdomen: (i) Inspection: - Mild abdominal distension - Reduced abd. movement at Rt iliac fossa
  41. 41. (ii) Palpation: Rt iliac fossa: - Guarding (indicator of tenderness severity) - Tenderness, Rebound tenderness - +ve Rovsing’s sign (iii) Percussion: pain at Rt iliac fossa (iv) Auscultaion: Bowel sound present Bowel sound absent when perforation & generalised peritonitis cause paralytic ileus
  42. 42. 1. abdominal pain <72 hours 2. Vomiting 1-3 times 3. Facial flush 4. Tenderness at Rt iliac fossa 5. Low-grade pyrexia 6. no evidence of UTI
  43. 43.  No need if it can be diagnosed through history and physical examination  AXR for confusing findings, may detect free gas from perforated appendix.
  44. 44. 1. UTI 2. Mesenteric adenitis 3. Constipation 4. Gynaecological disorder (ectopic pregnancy) 5. Acute pancreatitis 6. Diverticulitis 7. Perforated ulcer
  45. 45.  Medical ◦ Antibiotics  Surgical ◦ Appendicectomy  Abdominal wall incision ( Lanz/ Classic Gridiron incision)  Dividing the blood supply  Removing the appendix  Closure
  46. 46. 1. Perforation 2. Appendiceal mass (usually resolve in the next 2-6 weeks) - pyrexia - LOA - malaise - dull on percussion 3. Appendiceal abscess (formed from appendiceal mass that fails to resolve) - swinging pyrexia - tachycardia
  47. 47. Aetiology : - Gallstones (38%-60%) - Ethanol (35%) - Trauma (1.5%) - Mumps - Autoimmune (PAN) - Scorpion venom - Hyperlipidemia, hypercalcemia, hyperthyroidism - ERCP (5%) & emboli - Drugs * 10%-20% idiopathic
  48. 48. Duodenopancreatic reflux Enterokinase reflux Activate pancreatic proenzymes Inflammation, arterioles thrombose, local infarction More proenzymes leak out of necrotic cells to be activated Widespread autodigestion Obstuction of pancreatic duct
  49. 49. 1. Mild attack: - Acute interstitial pancreatitis 2. Severe attack: - Acute haemorrhagic pancreatitis - Acute necrotising pancreatitis
  50. 50. 1. epigastric pain: - sudden onset - radiate to back - no relieving factor - aggrevated by movement - assoc. with - Nausea & Vomiting
  51. 51. 1. General appearance: - in pain - pale - sweating - dyspneic & cyanosed (respiratory distress in severe attack) - jaundice - tachycardic - signs of hypovoolemic shock
  52. 52. 2. Abdomen: (i) Inspection: - mild abdominal distension - Grey Turner’s sign only in Acute Haemorrhagic - Cullen’s sign Pancreatitis
  53. 53. - fullness in epigastrium (abscess, pseudocyst) (ii) Palpation: - Tender - Guarding - Rebound tenderness (iii) Percussion: - Pain >> peritonitis - Dullness >> pseudocyst
  54. 54. (iv) Auscultation: - Bowel sound present in first 24 hrs - Bowel sound absent when paralytic ileus develops
  55. 55. 1. FBC (WBC ,RBC ) 2. Plasma amylase (>1200 IU/mL), (rises within 12 hrs, return to normal in next 48- 72 hrs) 3. Plasma lipase (elevated level persists for 7-10 days), usefull in late-presenting cases 4. LFT (bilirubin usually ) 5. ABG (hypoxia occurs in severe attack)
  56. 56. 6. Plain CXR (free gas under diaphragm) 7. Plain AXR (no psoas shadow >>retroperitoneal fluid) 8. Ultrasound 9. CT scan to confirm pancreatitis if amylase level normal 10. ERCP (to find the cause)
  57. 57. 1.Scoring system by Ranson 2.Glasgow Criteria by Imrie
  58. 58. A. At admission or diagnosis B. During initial 48 hrs 1. Age >55 years (70yrs in gall stone disease) 1. Hematocrit fall >10 percent 2. Leukocytosis >16,000 /mm3 2. Fluid sequestration >6L 3. Hyperglycemia >10 mmol/L 3. Hypocalcemia <2mmol/L 4. Serum LDH >400 IU/L 4. Hypoxemia (PO2 <60 mmHg) 5. Serum AST >250 IU/L 5. BUN rise >10mmol/L after IV fluids 6. Hypoalbuminemia <3.2 g/dL
  59. 59.  A - Age > 55  P - PO2 < 8 kPa (60mmHg) n=10.6  N - Neutrophil count ( > 16 x 109 /L )  C - Calcium < 2.0 mmol/L  R - Raised Urea > 10 mmol/L  E - Enzyme (LDH > 350 IU/L)  A – Albumin (plasma) < 32 g/L  S - Sugar (plasma glucose) >10mmol/L in the absence of history of diabetes) * (3 or > factors indicates severe pancreatitis)
  60. 60.  clinical assessment, relief of pain and resuscitation come before imaging tests Hematology biochemistr y imaging
  61. 61. Blood tests 1.Haemoglobin ◦ -may be normal immediately after an acute bleed ◦ -low haemoglobin concentration may represent chronic anaemia due to occult blood loss 2.White blood count -leucocytosis is non-specific and rarely of much diagnostic value unless greater than about 14 × 103/L 3.Pcv—degree of hydration(vomit,diarhoea) 4.Blood culture-only in patients with rigors or shock without obvious blood loss 5.Blood group and ordering of blood for transfusion- for severely anaemic patients, in major haemorrhage or when major surgery is contemplated
  62. 62. 1.C-reactive protein ◦ -non-specific indicator of inflammatory activation ◦ -confirms organic illness if substantially elevated 2.Plasma amylase-whenever pancreatitis cannot be excluded 3.Urea and electrolytes-indicated in vomiting and diarrhoea, dehydration, poor urine output, diuretic therapy, urinary tract disease, known or suspected renal failure, pancreatitis and sepsis
  63. 63. 4.Glucose-for diabetics or those with glycosuria (beware of hyperglycaemia due to acute stress or steroid therapy) 5.Liver function tests and calcium estimation-for pancreatitis and acute biliary disease 6.Clotting studies-for acute pancreatitis and septicaemia (DIC), severe bleeding (consumption coagulopathy) or those with a history of bleeding disorders
  64. 64. 1.Plain radiography 1.Erect chest X-ray ◦ -cardiovascular disease or abnormality, e.g. cardiomegaly, thoracic aneurysm, aortic dissection, cardiac failure ◦ -respiratory disease ◦ -suspected visceral perforation (gas under diaphragm)
  65. 65. 2.Supine abdominal X-ray (erect or decubitus if necessary) ◦ -bowel (gas pattern and dilatation, fluid levels, gas in the wall, faeces and faecoliths) ◦ -urinary tract ('KUB' = kidneys, ureters and bladder) shows kidney size and position, calculi ◦ -biliary tract (gallstones, gas in biliary tree in gallstone ileus) ◦ -aortic calcification (aneurysm) ◦ -psoas shadows (obscured by retroperitoneal inflammation or haemorrhage
  66. 66. 2.Ultrasound  Gallstones  Pelvic abnormalities in obstetric and gynaecological practice  'Chronic' enlargement of the spleen  Abdominal aortic aneurysm (AAA)  Free abdominal fluid and gas indicating perforated bowel  Other stones  Dilated ducts; air in biliary tree  Hydatid, teratomas and other cysts  Intra-abdominal abscesses and masses 3.Contrast radiology  'Instant' barium enema in colonic obstruction or acute colitis  Emergency intravenous urography in ureteric colic
  67. 67. 4. CT scanning  rapid, cost-effective evaluation of acute abdominal pain Assessment of abdominal trauma-severity and grading of solid organ injury, free intra-abdominal fluid and gas; retroperitoneal injuries including pancreatic and duodenal rupture and vascular injury  Often first choice for ureteric colic, suspected aortic aneurysm or aortic dissection  Useful where diagnosis remains in doubt, e.g. suspected bowel perforation (detects small amount of free gas), acute diverticulitis  Investigation of postoperative complications-abscesses, fluid collections  Severe acute pancreatitis, especially if necrosis suspected
  68. 68.  Duodenal ulcer: • Surgery (ulcer is sutured or plugged using an omentum patch) • Supportive treatment with nasogastric suction  Gastric ulcer: • ~15% of perforated gastric ulcer prove to be malignant. Therefore, definitive surgery is preferred • Simple closure with biopsy @ local excision (in poor-risk patients)
  69. 69.  Acute cholecystitis  1st line treatment (medical) : Fasting, intravenous fluid, analgesic Start IV antibiotics (if pt has systemic signs or if no improvement after 12-24 hours)  Surgery: Emergency vs elective Open vs laparoscopic
  70. 70. Laparoscopic Cholecystectomy  Optimal management contraindications advantages disadvantages (i) Uncorrectable Coagulopathy (ii) Unable to tolerate GA (iii) Known GB ca (i) Lower mortality (ii) Less pain (iii) Shorter hosp stay (iv) Recovery rate faster (i) Higher incidence of injury to the common hepatic and bile ducts (ii) Inj tend to be more extensive
  71. 71.  Pain after cholecystectomy (I) retained or recurrent stone (ii) iatrogenic biliary leak (iii) stricture of CBD (iv) papillary stenosis/dysfunction of Sphincter of Oddi (v) incorrect pre-op dx (eg irritable bowel syndrome, PUD, GOR
  72. 72.  Other treatment modalities : (I) Oral bile acid treatment - monotherapy or combine therapy (6-12 months) - ursodeoxycholic acid and chenodeoxycholic acid (ii) Contact dissolution therapy - chemical litholysis of cholesterol stones (MTBE) (iii) ESWL - used when GB is functioning ; technically difficult when it is subcoastal - long term recurrence rate high (between 28-61%) (iv) percutaneous cholecystectomy
  73. 73. Criteria for non surgical treatment of gallstones:  Cholesterol stones (<20mm in diameter)  Fewer than 4 stones  Functioning gallbladder  Patent cystic duct  Mild symptoms
  74. 74. MILD ATTACK  Hourly pulse, BP, urine output  Fluid resuscitation to replace fluid loss from profuse vomiting  Analgesics for pain relief – pethidine, morphine  Withhold oral intake  Treat predisposing factors  Remove stone endoscopically, stopped taking alcohol, laparoscopic cholecyctectomy with operative cholangiography before discharge.  Nasogastric tube to aspirate gastric content & relief discomfort.  Prophylactic parenteral antibiotic (cephalosporin) given.  Daily measurement of serum amylase, ABG, BUSE, LFT and serum calcium & phosphate to monitor progress
  75. 75. SEVERE ATTACK  Admit to ICU for close monitoring and early Rx of complications  Evaluated every 48 hours.  May die early b’coz of systemic toxaemia and multiple organ dysfunction.  If PaO2 deteriorating- urgent ventilation support before ARDS  Massive fluid & electrolytes loss esp protein-rich fluid into peritoneal cavity and 3rd space lead to shock  Rx- fluid resuscitation with large amount of colloid & crystalloid  Monitor urine output & central venous pressure.  Peritoneal lavage – reduce systemic absorption of enzymes & toxins.  Intravenous nutrition given in paralytic ileus patient
  76. 76.  Medical ◦ Antibiotics  Surgical ◦ Appendicectomy  Gridiron / Lanz skin incision  Abdominal wall incision  Dividing the blood supply  Removing the appendix  Closure
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