Describes about the importance of vitamins in our daily activities , classification of vitamins,various sources of vitamins and also about the problems which occurs due to the deficiency of vitamins.
Chemistry of Vitamin E, Biochemical role of Vitamin E, Recommended dietary Allowances, Dietary sources of Vitamin E, Deficiency symptoms of vitamin E, Hypervitaminosis of vitamin E, Toxicity of Vitamin E,
Describes about the importance of vitamins in our daily activities , classification of vitamins,various sources of vitamins and also about the problems which occurs due to the deficiency of vitamins.
Chemistry of Vitamin E, Biochemical role of Vitamin E, Recommended dietary Allowances, Dietary sources of Vitamin E, Deficiency symptoms of vitamin E, Hypervitaminosis of vitamin E, Toxicity of Vitamin E,
Small amounts of vitamins are required in the diet to promote growth, reproduction, and health. Vitamins A, D, E, and K are called the fat-soluble vitamins, because they are soluble in organic solvents and are absorbed and transported in a manner similar to that of fats.
Definition
Classification
Introduction
Types of WATER SOLUBLE vitamin
Public health significance
Dietary goals
Dietary guidelines
Vitamin C
the B Vitamins
Thiamin (Vitamin B1)
Riboflavin (Vitamin B2)
Niacin (Vitamin B3)
Pantothenic Acid
Vitamin B6
Folic Acid
Vitamin B12
Nutritional programmes in india
Small amounts of vitamins are required in the diet to promote growth, reproduction, and health. Vitamins A, D, E, and K are called the fat-soluble vitamins, because they are soluble in organic solvents and are absorbed and transported in a manner similar to that of fats.
Definition
Classification
Introduction
Types of WATER SOLUBLE vitamin
Public health significance
Dietary goals
Dietary guidelines
Vitamin C
the B Vitamins
Thiamin (Vitamin B1)
Riboflavin (Vitamin B2)
Niacin (Vitamin B3)
Pantothenic Acid
Vitamin B6
Folic Acid
Vitamin B12
Nutritional programmes in india
Vitamins are required in small quantities in the diet because they cannot be synthesized by the body.
Water soluble vitamins cannot be stored in human tissues. Their excess is excreted with urine.
Significant amounts of fat soluble vitamins can be stored in adipose tissue and the liver.
Synthetic vitamins are identical to natural vitamins.
Once growth and development are completed, vitamins remain essential nutrients for the healthy maintenance of the cells, tissues, and organs.
Vitamins are organic compounds that are essential for normal growth and nutrition and are required in small quantities, their deficiency causes diseases.
Biochemist Casimir Funk discovered vitamin B1 in 1912 in rice bran.
It cannot be synthesized in sufficient quantities by an organism and must be obtained from the diet.
A vitamin that can dissolve in water. Vitamins are nutrients that the body needs in small amounts to stay healthy and work the way it should. Water-soluble vitamins are carried to the body's tissues but are not stored in the body.
A Comprehensive Introduction to Vitamins and its chemistry, source, RDA, classification, deficiency states and biological importance. This will give readers a overall insight to this topic.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
3. The word "vitamin" comes from the Latin word “vita”, means
"life".
Vitamins are essential nutrients found in foods. They perform
specific and vital functions in a variety of body systems, and are
crucial for maintaining optimal health.
1.Introduction
3
4. Vitamins are required in small quantities in the diet because they cannot
be synthesized by the body.
Water soluble vitamins cannot be stored in humantissues.
Their excess is excreted with urine.
Significant amounts of fat soluble vitamins can be stored in adipose
tissue and the liver.
Synthetic vitamins are identical to naturalvitamins.
Once growth and development are completed, vitamins remain essential
nutrients for the healthy maintenance of the cells, tissues, and organs.
2.General characteristics
4
5. Vitamins are helpful for the health and life of the
body in the following respects:
(a) They build up the resistance of the body against diseases.
(b) Prevent and cure various diseases caused by deficiency.
(c) Help the digestion and utilization of mineral salts and Carbohydrates in the body.
(d) Stimulate and give strength to digestive and nervous system.
(e) Help health protection.
(f) Help maintenance of proper health and normal growth.
3. General Functions
5
6. 4. Classification
On the basis of their solubility vitamins are mainly 2 types-
1. Fat-soluble vitamins and
2. Water-soluble vitamins.
※ Fat-soluble vitamins:- vitamins A, D, E and K — dissolve in fat before they are
absorbed in the bloodstream to carry out their functions. Excesses of these vitamins are
stored in the liver, and are not needed every day in the diet.
※ In contrast, water-soluble vitamins dissolve in water and are not stored by the
body. Since they are eliminated in urine, we require a continuous daily supply in our
diet.
6
7. ※ The water-soluble vitamins include the vitamin B-complex group and vitamin C.
※ Water-soluble vitamins are easily destroyed or washed out during food storage or
preparation. Proper storage and preparation of food can minimize vitamin loss. To reduce
vitamin loss, always refrigerate fresh produce, keep milk and grains away from strong light,
and avoid boiling vegetables with the exception of soups where the broth is eaten.
7
9. 9
5.INDIVIDUAL CHARACTERISTIC
WATER SOLUBLE VITAMINS (B-COMPLEX VITAMINS)
It is also called Anti Beri-Beri factor, Anti Neuritic factor, and also Aneurin.
The Recommended Dietary Allowance (RDA) for thiamin is
1.2 mg/day for adult males and
1.1 mg/day for adult females
DAILY REQUIRMENT
VITAMIN-B1
10. 10
DIETARY SOURCES
FUNCTION
※ Act as co-enzyme
※ Essential for synthesis of healthy nerve.
※ Promotes normal appetite, and
※ Plays a role in muscle contraction and conduction of nerve signals.
DEFICIENCY
BERI-BERI
11. 11
It is also called as beauty vitamin.
The Recommended Dietary Allowance (RDA) for riboflavin is
1.3 mg/day for adult males
1.1 mg/day for adult females
DAILY REQUIRMENT
DIETARY SOURCES
VITAMIN:- B2
12. 12
• In humans riboflavin deficiency causes oral, facial, occular
lesions.
• Hair loss
• Growth failure
DEFICIENCY (Ariboflavinosis)
FUNCTION
Act as Coenzyme in energy metabolism of fat, carbohydrate, and
protein.
13. 13
Vitamin B3 is also known as niacin or nicotinic acid.
it is essential for metabolism of carbohydrate, protein & fat.
DAILY REQUIRMENT
16 mg/day for adult males and
14 mg/day for adult females
DIETARY SOURCES
VITAMIN:- B3
14. 14
FUNCTION
Vitamin B3, helps in releasing energy from carbohydrates, fats and
protiens.
Essential for the DNAsynthesis.
Essential for production of estrogen progesterone & testosterone
Also helpful in reducing migraine headaches.
DEFICIENCY
• Niacin deficiency causes pellagra in which skin, gastrointestinal
tract and nervous system are affected.
15. 15
VITAMIN-B-5
Vitamin B5 is also known as Pantothenic Acid, is a water-soluble vitamin.
This word derived from greek word pantos meaning everywhere.
DAILY REQUIRMENT
5 mg/day for both adult males & females .
DIETARY SOURCES
Almost all plant- and animal- based foods contain pantothenic acid in varying amounts.
FUNCTION
Act as Coenzyme in energy metabolism of fat, carbohydrate, and
protein
DEFICIENCY
Uncommon.
16. 16
VITAMIN- B-6
Vitamin B6, also known as pyridoxine.
DAILY REQUIRMENT
The Recommended Dietary Allowance (RDA) for vitamin B6 is :
1.3 mg/day for adult males and females
DIETARY SOURCES
17. 17
FUNCTION
Coenzyme in amino acid and lipid metabolism
Hemoglobin synthesis
Homocysteine metabolism
Act as antioxidant molecule
Helps in production of chemicals such as neurotransmitters and
hemoglobin.
Maintain normal nerve function
DEFICIENCY
Dermatitis
Depression
Convulsions, confusion, anemia
Peripheral neuritis
swollen tongue
18. 18
VITAMIN-B-7
DAILY REQUIRMENT
Vitamin B7 or Biotin, also known as vitamin H or coenzyme R, is a
water-solubleB-vitamin.
Biotin helps release energy from carbohydrates and aids in the metabolism
of fats, proteins and carbohydrates from food.
RDA IS 30 mcg/day for adult males and adult females.
DIETARY SOURCES
19. 19
FUNCTION
Act as Coenzyme in energy metabolism of
fat, carbohydrate, and protein
Maintenance of normal skin and mucous
membranes
Maintenance of normal hair;
The normal function of the nervous system;
DEFICIENCY
Rare
20. 20
VITAMIN- B -9
Vitamin B9 is also known as folic acid, folacin or folate.
It is a water soluble vitamin.
It is a yellow crystalline substance.
DAILY REQUIRMENT
The Recommended Dietary Allowance (RDA) for folate is 400
mcg/day for adult males and females. Pregnancy will increase the
RDA for folate to 600 mcg/day.
22. 22
Formation of RBC
Nerve – it is necessary for growth & division of all body cells,
Hair & Skin – it is essential for the health of skin &hair
Pregnancy – it is an important nutrient for the pregnant women &
her developing fetus.& folic acid improves the lactation.
DNAsynthesis
Homocysteine metabolism
Neurotransmitter formation
FUNCTION
DEFICIENCY
Megaloblastic anemia,
Neural tube defects: spina bifida
Affects cell growth and protein production
23. 23
VITAMIN- B- 12
Vitamin B12 is complex organomatrix compound called as cobalamin
which is cobalt containing porphyrin. It is freely soluble in water.
DAILY REQUIRMENT
2.4 mcg/day for adult males and females .
DIETARY SOURCES
All animal foods, fortified cereals
24. 24
FUNCTION
Maturation of RBC
Requires intrinsic factor from parietal cells for absorption
Cofactor in folate and homocysteine metabolism
Helps in maintenance of Nervous system.
DEFICIENCY
ANEMIA
Demyelination & irreversible nerve cell death.
25. 25
VITAMIN- C
It is also called ascorbic acid and antibiotic vitamin.
it is the most active reducing agent.
it is powerful antioxidant
Synthesized by most animals (not by human)
DAILY REQUIRMENT
The Recommended Dietary Allowance (RDA) for Vitamin C is 90 mg/day for
adult males and 75 mg/day for adult females
27. 27
FUNCTION
※ Boosting immunity.
※ Antioxidant
※ Collagen synthesis
※ Wound healing
※ Aids in absorption of iron
※ Strengthening blood vessels walls
※ Treating allergy-related conditions, such as asthma, eczema, and hay fever (called
allergic rhinitis).
30. 30
Gingiva is often swollen, red and edematous.
Inflammation often involves free gingiva, attached gingiva and alveolar mucosa.
Gingiva becomes brilliant red, tender and grossly swollen.
Spontaneous bleeding or bleeding on gentle stimulation such that while chewing is
common.
On long standing, the color may change to dark blue or purple.
Ulceration may occur leading to secondary infections.
Alveolar bone resorption with increased tooth mobility is seen
Periodontal features of scurvy:
31. 31
FAT SOLUBLE VITAMINS:-
※ VITAMIN-A
Vitamin A is a group of unsaturated nutritional organiccompounds, that includes
retinol, retinal, retinoic acid, and
several provitamin A carotenoids, among which beta-carotene is the most
important. Its active form is present only in AnimalTissue
DAILY REQUIRMENT
Recommended Dietary Allowance (RDA) for vitamin A is
※ 900 mcg/ day for adult males
※ 700 mcg/day for adult females.
33. 33
FUNCTION
Vitamin A plays a role in a variety of functions throughout
the body, such as:
Vision
Gene transcription
Immune function
Embryonic development and reproduction
Bone metabolism
Hematopoiesis (the production of blood cells and platelets)
Skin and cellular health
Antioxidant activity
34. 34
DEFICIENCY
Night blindness
Xerophthalmia
Poor growth
Keratinization of epithelium
Dry, scaly skin
Toxic in large doses: double vision, hair loss, dry mucous
membranes, joint pain, liver damage
35. 35
Vitamin D refers to a group of fat-soluble secosteroids (a type of steroid with a
"broken" ring) found in liver and fish oils, or obtained by irradiating
provitamin D with ultraviolet light and are responsible for enhancing intestinal
absorption of calcium, iron, magnesium, phosphate and zinc. It is also called
SUNSHINE VITAMIN.
DAILY REQUIRMENT
※ VITAMIN-
Men and women- 0.01 mg.
Pregnancy and lactation– 0.01 mg
Infants & Children –0.01 mg
37. 37
Calcium Balance
Cell Differentiation
Immunity
Blood Pressure Regulation
Development of Bones & Teeth
FUNCTION
DEFICIENCY
1. Rickets
2. Osteomalacia
3. Osteoporosis
38. 38
※ VITAMIN-E
※ Chemically they are tocopherol
※ It is also called anti-aging factor.
※ They are naturallyoccurring anti oxidant.
They are derivatives of tocol or 6-hydroxy chromane ring with phytyl side chain.
39. 39
DAILY REQUIRMENT
RDA guidelines state that males and females over the age of 14 should receive
15 mcg (22.5 IUs) of alpha-tocopherol per day.
DIETARY SOURCES
40. 40
FUNCTION
Antioxidant (most powerful natural)
Free radical scavenger
Protects cell membranes
Prevention of rancidity
Skin protection
DEFICIENCY
Vitamin E deficiency is rare.
41. 41
※ VITAMIN-
Vitamin K is naturally produced by the bacteria in the
intestines.
It is essential for production of a type of protein called prothrombin & other factor
involve in blood clotting mechanism. Hence it is known as anti – hemorrhagic
vitamin.
DAILY REQUIRMENT
Men and women – 70 – 140 mcg.
Children – 35 – 75mcg.
43. 43
FUNCTION
It is essential for the hepatic synthesis of
coagulation factor II, V,VII, IX, X.
CLOTTING – it prevents hemorrhage only in cases when there is defective
production of prothrombin
OXIDATIVE PHOSPHORYLATION
DEFICIENCY
Prolonged clotting time
Hemorrhage
44. 44
REFRENCES:-
http://en.wikipedia.org/wiki/Vitamin
http://www.precisionnutrition.com/all-about-vitamins-
http://www.encyclopedia.com/topic/vitamin.aspx
Berdanier, C.D., & Berdanier, L. (2015). Advanced Nutrition: Macronutrients, Micronutrients,
and Metabolism, Second Edition. Oakville: CRC Press. Gropper, S.A., Smith, J.L., & Carr,
T.P. (2018).
Advanced Nutrition and Human Metabolism, Seventh Edition. Boston, MA: Cengage
Learning. Stipanuk, M.H., & Caudill, M.A. (2018).
Biochemical, Physiological, Molecular Aspects of Human Nutrition, Fourth Edition. St.
Louis, MO: Elsevier. Duyff R.L. (2017).
Academy of Nutrition and Dietetics Complete Food and Nutrition Guide, Fifth Edition.
Boston: Houghton Mifflin Harcourt. National Institute of Health (2018).
[U Satyanarayana] Biochemistry