A urethral stricture is a narrowing of the urethra caused by injury, infection or instrumentation that blocks the flow of urine. Risk factors include being male as male urethras are longer and more susceptible to disease or injury. Common causes are trauma, sexually transmitted infections, catheterization or prostate surgery. Symptoms include painful urination, slow urine stream, decreased urine output and urinary tract infections. Diagnosis involves history, exam, imaging tests and cystoscopy. Treatment options include dilation, urethrotomy, urethroplasty or stents to reopen the blocked urethra. Complications can include urinary retention, infections and kidney damage if left untreated.