Uremic encephalopathy occurs when toxins that are normally cleared by the kidneys build up in the bloodstream due to kidney failure. It causes a range of neurological symptoms from mild issues like fatigue to severe problems like seizures and coma. The condition develops when kidney function declines to the point that creatinine clearance levels fall below 15 mL/min. While the exact cause is unknown, it involves the accumulation of various toxins in the brain that disrupts cell metabolism and function. Prompt treatment with dialysis or kidney transplantation can reverse the neurological symptoms.

3. Uremic Encephalopathy Dr. Abrar Ali Katpar Resident Nephrology King Khalid Hospital, Hail, K.S.A

28. Workup

46. Lumbar puncture

47. Treatment

53. Follow-up

60. Thank You