The document provides guidelines for universal and transmission-based precautions for healthcare workers. It discusses different types of precautions including airborne, droplet, and contact precautions. Airborne precautions require a private room with negative air pressure for patients with illnesses transmitted via airborne particles like tuberculosis. Droplet precautions require a private room or spatial separation of 3 feet for illnesses transmitted by droplets like influenza. Contact precautions require a private room and use of gloves and gowns for direct and indirect contact transmission of illnesses like MRSA. Handwashing and proper handling of equipment, linen and waste is also covered.