Transplants and eugenics raise complex ethical issues. Transplants require lifelong immunosuppressant drugs and organ shortages remain an issue. Eugenics aims to improve genetics but has been discredited due to flawed science and links to atrocities. While genetic screening now focuses on counseling rather than control, debates continue on prenatal testing, genetic engineering, and enhancing traits.
This ppt have a detailed source about the Biosafety issues in Biotechnology and their implements over by the government. It have a topics about the issues in antibiotic resistance gene , GMO crops etc.
This ppt have a detailed source about the Biosafety issues in Biotechnology and their implements over by the government. It have a topics about the issues in antibiotic resistance gene , GMO crops etc.
Ethical issues in biotechnology and related areas.
For soft copy of this document please feel free to contact us on info@biotechsupportbase.com or snjogdand@gmail.com
Ethical implication of Human genome project,
International ethical & legal issues connected with human genome diversity research,
Genetic studies of ethnic races.
Ethical issues related to animal biotechnologyKAUSHAL SAHU
Introduction
Why are genetically modified animals produced?
Examples of transgenic animals
Why are animals used instead of genetically modified microbes or plants?
Ethical issues
Religious concerns
Responsibility of Scientists
Need for Guidelines
Conclusion
References
What is Genome,Genome mapping,types of Genome mapping,linkage or genetic mapping,Physical mapping,Somatic cell hybridization
Radiation hybridization ,Fish( =fluorescence in - situ hybridization),Types of probes for FISH,applications,Molecular markers,Rflp(= Restriction fragment length polymorphism),RFLPs may have the following Applications;Advantages of rflp,disAdvantages of rflp, Rapd(=Random amplification of polymorphic DNA),Process of rapd, Difference between rflp &rapd
History,evaluation,principles and players of bioethics its importance why it is prerequisite to follow ,how to resolve a dilemma which arise during a research and to make considerations in such dilemma
Ethical issues in biotechnology and related areas.
For soft copy of this document please feel free to contact us on info@biotechsupportbase.com or snjogdand@gmail.com
Ethical implication of Human genome project,
International ethical & legal issues connected with human genome diversity research,
Genetic studies of ethnic races.
Ethical issues related to animal biotechnologyKAUSHAL SAHU
Introduction
Why are genetically modified animals produced?
Examples of transgenic animals
Why are animals used instead of genetically modified microbes or plants?
Ethical issues
Religious concerns
Responsibility of Scientists
Need for Guidelines
Conclusion
References
What is Genome,Genome mapping,types of Genome mapping,linkage or genetic mapping,Physical mapping,Somatic cell hybridization
Radiation hybridization ,Fish( =fluorescence in - situ hybridization),Types of probes for FISH,applications,Molecular markers,Rflp(= Restriction fragment length polymorphism),RFLPs may have the following Applications;Advantages of rflp,disAdvantages of rflp, Rapd(=Random amplification of polymorphic DNA),Process of rapd, Difference between rflp &rapd
History,evaluation,principles and players of bioethics its importance why it is prerequisite to follow ,how to resolve a dilemma which arise during a research and to make considerations in such dilemma
Gene counselling a developing field has more effect on both the developing and developed countries. So this ppt provides the basic idea about genetic counselling
Cloning, types and challenges
What types of cloning have been successful?
What are the Three Types of Cloning?
Human Cloning: The Good and The Bad
Ethical Issues regarding Human Reproductive Cloning
Challenges
Global and Religious Views
Final Thought
Assisted Reproductive Technologies (ART)
First Successful IVF: Birth of Louise Brown in 1978
Rapid developments in the field of ART
Moral panic
Ethics
Ethical issues
Ethical concerns
Moral issues
Social issues
Religion
Case study
Eugenics is the science which deals with all influences that improve inborn qualities of a race, also with those that develop them to almost advantage.
Connector Corner: Automate dynamic content and events by pushing a buttonDianaGray10
Here is something new! In our next Connector Corner webinar, we will demonstrate how you can use a single workflow to:
Create a campaign using Mailchimp with merge tags/fields
Send an interactive Slack channel message (using buttons)
Have the message received by managers and peers along with a test email for review
But there’s more:
In a second workflow supporting the same use case, you’ll see:
Your campaign sent to target colleagues for approval
If the “Approve” button is clicked, a Jira/Zendesk ticket is created for the marketing design team
But—if the “Reject” button is pushed, colleagues will be alerted via Slack message
Join us to learn more about this new, human-in-the-loop capability, brought to you by Integration Service connectors.
And...
Speakers:
Akshay Agnihotri, Product Manager
Charlie Greenberg, Host
Let's dive deeper into the world of ODC! Ricardo Alves (OutSystems) will join us to tell all about the new Data Fabric. After that, Sezen de Bruijn (OutSystems) will get into the details on how to best design a sturdy architecture within ODC.
State of ICS and IoT Cyber Threat Landscape Report 2024 previewPrayukth K V
The IoT and OT threat landscape report has been prepared by the Threat Research Team at Sectrio using data from Sectrio, cyber threat intelligence farming facilities spread across over 85 cities around the world. In addition, Sectrio also runs AI-based advanced threat and payload engagement facilities that serve as sinks to attract and engage sophisticated threat actors, and newer malware including new variants and latent threats that are at an earlier stage of development.
The latest edition of the OT/ICS and IoT security Threat Landscape Report 2024 also covers:
State of global ICS asset and network exposure
Sectoral targets and attacks as well as the cost of ransom
Global APT activity, AI usage, actor and tactic profiles, and implications
Rise in volumes of AI-powered cyberattacks
Major cyber events in 2024
Malware and malicious payload trends
Cyberattack types and targets
Vulnerability exploit attempts on CVEs
Attacks on counties – USA
Expansion of bot farms – how, where, and why
In-depth analysis of the cyber threat landscape across North America, South America, Europe, APAC, and the Middle East
Why are attacks on smart factories rising?
Cyber risk predictions
Axis of attacks – Europe
Systemic attacks in the Middle East
Download the full report from here:
https://sectrio.com/resources/ot-threat-landscape-reports/sectrio-releases-ot-ics-and-iot-security-threat-landscape-report-2024/
Essentials of Automations: Optimizing FME Workflows with ParametersSafe Software
Are you looking to streamline your workflows and boost your projects’ efficiency? Do you find yourself searching for ways to add flexibility and control over your FME workflows? If so, you’re in the right place.
Join us for an insightful dive into the world of FME parameters, a critical element in optimizing workflow efficiency. This webinar marks the beginning of our three-part “Essentials of Automation” series. This first webinar is designed to equip you with the knowledge and skills to utilize parameters effectively: enhancing the flexibility, maintainability, and user control of your FME projects.
Here’s what you’ll gain:
- Essentials of FME Parameters: Understand the pivotal role of parameters, including Reader/Writer, Transformer, User, and FME Flow categories. Discover how they are the key to unlocking automation and optimization within your workflows.
- Practical Applications in FME Form: Delve into key user parameter types including choice, connections, and file URLs. Allow users to control how a workflow runs, making your workflows more reusable. Learn to import values and deliver the best user experience for your workflows while enhancing accuracy.
- Optimization Strategies in FME Flow: Explore the creation and strategic deployment of parameters in FME Flow, including the use of deployment and geometry parameters, to maximize workflow efficiency.
- Pro Tips for Success: Gain insights on parameterizing connections and leveraging new features like Conditional Visibility for clarity and simplicity.
We’ll wrap up with a glimpse into future webinars, followed by a Q&A session to address your specific questions surrounding this topic.
Don’t miss this opportunity to elevate your FME expertise and drive your projects to new heights of efficiency.
LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...DanBrown980551
Do you want to learn how to model and simulate an electrical network from scratch in under an hour?
Then welcome to this PowSyBl workshop, hosted by Rte, the French Transmission System Operator (TSO)!
During the webinar, you will discover the PowSyBl ecosystem as well as handle and study an electrical network through an interactive Python notebook.
PowSyBl is an open source project hosted by LF Energy, which offers a comprehensive set of features for electrical grid modelling and simulation. Among other advanced features, PowSyBl provides:
- A fully editable and extendable library for grid component modelling;
- Visualization tools to display your network;
- Grid simulation tools, such as power flows, security analyses (with or without remedial actions) and sensitivity analyses;
The framework is mostly written in Java, with a Python binding so that Python developers can access PowSyBl functionalities as well.
What you will learn during the webinar:
- For beginners: discover PowSyBl's functionalities through a quick general presentation and the notebook, without needing any expert coding skills;
- For advanced developers: master the skills to efficiently apply PowSyBl functionalities to your real-world scenarios.
Smart TV Buyer Insights Survey 2024 by 91mobiles.pdf91mobiles
91mobiles recently conducted a Smart TV Buyer Insights Survey in which we asked over 3,000 respondents about the TV they own, aspects they look at on a new TV, and their TV buying preferences.
Dev Dives: Train smarter, not harder – active learning and UiPath LLMs for do...UiPathCommunity
💥 Speed, accuracy, and scaling – discover the superpowers of GenAI in action with UiPath Document Understanding and Communications Mining™:
See how to accelerate model training and optimize model performance with active learning
Learn about the latest enhancements to out-of-the-box document processing – with little to no training required
Get an exclusive demo of the new family of UiPath LLMs – GenAI models specialized for processing different types of documents and messages
This is a hands-on session specifically designed for automation developers and AI enthusiasts seeking to enhance their knowledge in leveraging the latest intelligent document processing capabilities offered by UiPath.
Speakers:
👨🏫 Andras Palfi, Senior Product Manager, UiPath
👩🏫 Lenka Dulovicova, Product Program Manager, UiPath
Slack (or Teams) Automation for Bonterra Impact Management (fka Social Soluti...Jeffrey Haguewood
Sidekick Solutions uses Bonterra Impact Management (fka Social Solutions Apricot) and automation solutions to integrate data for business workflows.
We believe integration and automation are essential to user experience and the promise of efficient work through technology. Automation is the critical ingredient to realizing that full vision. We develop integration products and services for Bonterra Case Management software to support the deployment of automations for a variety of use cases.
This video focuses on the notifications, alerts, and approval requests using Slack for Bonterra Impact Management. The solutions covered in this webinar can also be deployed for Microsoft Teams.
Interested in deploying notification automations for Bonterra Impact Management? Contact us at sales@sidekicksolutionsllc.com to discuss next steps.
Builder.ai Founder Sachin Dev Duggal's Strategic Approach to Create an Innova...Ramesh Iyer
In today's fast-changing business world, Companies that adapt and embrace new ideas often need help to keep up with the competition. However, fostering a culture of innovation takes much work. It takes vision, leadership and willingness to take risks in the right proportion. Sachin Dev Duggal, co-founder of Builder.ai, has perfected the art of this balance, creating a company culture where creativity and growth are nurtured at each stage.
The Art of the Pitch: WordPress Relationships and SalesLaura Byrne
Clients don’t know what they don’t know. What web solutions are right for them? How does WordPress come into the picture? How do you make sure you understand scope and timeline? What do you do if sometime changes?
All these questions and more will be explored as we talk about matching clients’ needs with what your agency offers without pulling teeth or pulling your hair out. Practical tips, and strategies for successful relationship building that leads to closing the deal.
UiPath Test Automation using UiPath Test Suite series, part 3DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 3. In this session, we will cover desktop automation along with UI automation.
Topics covered:
UI automation Introduction,
UI automation Sample
Desktop automation flow
Pradeep Chinnala, Senior Consultant Automation Developer @WonderBotz and UiPath MVP
Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
Search and Society: Reimagining Information Access for Radical FuturesBhaskar Mitra
The field of Information retrieval (IR) is currently undergoing a transformative shift, at least partly due to the emerging applications of generative AI to information access. In this talk, we will deliberate on the sociotechnical implications of generative AI for information access. We will argue that there is both a critical necessity and an exciting opportunity for the IR community to re-center our research agendas on societal needs while dismantling the artificial separation between the work on fairness, accountability, transparency, and ethics in IR and the rest of IR research. Instead of adopting a reactionary strategy of trying to mitigate potential social harms from emerging technologies, the community should aim to proactively set the research agenda for the kinds of systems we should build inspired by diverse explicitly stated sociotechnical imaginaries. The sociotechnical imaginaries that underpin the design and development of information access technologies needs to be explicitly articulated, and we need to develop theories of change in context of these diverse perspectives. Our guiding future imaginaries must be informed by other academic fields, such as democratic theory and critical theory, and should be co-developed with social science scholars, legal scholars, civil rights and social justice activists, and artists, among others.
5. Transplant
An operation in which an organ or tissue is transplanted.
Organ transplant
The surgical removal of a healthy organ from one person and its transplantation
into another person whose organ has failed or was injured is often lifesaving and
gives the recipient a wonderful new lease on life.
e.g. heart, kidneys, liver, lungs, pancreas, intestine, and thymus
Tissue Transplant
Tissues include bones, tendons, cornea, skin, heart valves, nerves and veins.
6.
7. Organ transplant candidates need to make
some substantial lifestyle changes
• Such as losing a moderate or large amount of weight
• Stopping smoking
• Don’t be a silent sufferer!
• Dental cleaning is generally recommended every six months for
transplant recipients.
• Keep stress low
8. How long will it take?
Transplant surgery times differ a lot. A few examples
include:
• Liver, 5 to 8 hours
• Kidney, 4 to 5 hours
• Pancreas, 2 to 4 hours
• Both kidney and pancreas, 5 to 7 hours
Your surgeon can give you a better estimate, taking into
account your specific circumstances.
9. After the Treatment
• After an organ transplant, most patients quickly feel better. They go on to enjoy a significantly
improved quality of life.
• You will need to take immunosuppressant (anti-rejection) drugs. These drugs help prevent
your immune system from attacking ("rejecting") the donor organ. (for lifetime)
• Hair growth or hair loss
• Acne
• Mood swings
• Weight gain
• Diarrhea
• High blood pressure and High cholesterol
• Elevated blood sugar level
10. The symptoms of rejection
• The organ's function may start to decrease
• General discomfort, uneasiness, or ill feeling
• Pain or swelling in the area of the organ (rare)
• Fever (rare)
• Flu-like symptoms, including chills, body aches, nausea, cough, and shortness
of breath
• The symptoms depend on the transplanted organ or tissue. For example,
patients who reject a kidney may have less urine and patients who reject a heart
may have symptoms of heart failure
11. Precautions after Transplant
• Wash your hands often
• Avoid people who are sick.
• Avoid people who have been recently vaccinated.
• Stay out of crowded areas
• Don't take care of pets.
• Don't garden.
• Brush and floss daily.
• Don't ignore cuts or scratches.
13. Organ Transplantation:
• Organ donation is the donation of biological tissue or an organ of the human
body, from a living or dead person to a living recipient in need of a
transplantation
14. Ethical Principles:
• Autonomy
Implies that a person should be given choices in regards to the situations
involved in their dying
• Non-maleficence
Protects the patient from more harm. A patient can donate their vital organs for
as long as it does not cause further harm
16. Deontological Issues:
• Certain groups oppose organ donation on religious grounds,
• Most of the world's religions support donation as a charitable act of great benefit
to the community.
• Issues surrounding patient autonomy, living wills, and guardianship.
17. Cloning Issues
• The use of cloning to produce organs with an identical genotype to
the recipient has issues all its own.
• Creation of an entire being for the sole purpose of using it as spare
parts.
• zero-percent chance of transplant rejection.
• The use of cloning to produce organs.
• However, it may be possible in the future to use cloned stem-cells to
grow a new organ without creating a new human being.
18. Xenotransplant Issues
• Highly successful means of transplant
• Xenotransplantation, the transplantation of organs, tissues or cells from one
species to another.
• If applied to man, would offer the possibility of a huge supply of organs, tissues
and cells for transplantation thereby relieving the “chronic” shortage of human
donor.
19. Health Risks:
• the introduction of new infectious agents into the human population.
• Risk by means of two characteristics: the level of probability and the extent of
damage.
21. Eugenics
• Good genes” or “good birth”
• Term coined 1883
• The use of genetics to improve the health of a population.
• It is a movement that is aimed at improving the genetic composition of the
human race.
• Eugenicists advocated selective breeding to achieve these goals.
22. Defining Eugenics
• “Improving human genetic qualities”
• "Eugenics is the study of agencies under social control that may
improve or impair the racial qualities of future generations,
whether physically or mentally."
23. Eugenics is influenced by
• Origin of Species: Natural Selection
• “Survival of the fittest”
• Mendel’s studies on the inheritance of traits
• Agriculture/Animal Breeding
24. Types
• Eugenics can be divided into two types : Negative & positive eugenics
Positive eugenics:
Encourage people with “good genes” to have more children.
Negative selection:
People with inferior and undesirable trait are prevented from reproducing
. It don’t allow “bad genes” to be reproduced.
26. Negative Eugenics
Decrease frequency of deleterious genes
• 2 - 2.5% of children born in the US are markedly defective - mentally or
physically
• Two reasons for prevalence of deleterious genes
1. Although deleterious in homozygous condition, may produce hybrid vigor in
heterozygous
2. Frequency of deleterious genes is now high because natural selection has been
artificially reduced
27.
28. EXAMPLE
• Sterilization of men is done by vasectomy involving an operation in which sperm
duct is blocked.
• Sterilization of women is done by tubectomy which involves an operation in
which fallopian tube is blocked.
29. US Laws supporting Eugenics
• Miscegenation laws against mixing races
• Immigration Laws
Limits on Eastern and Southern Europeans (based on IQ tests, inmate/asylum
studies
• Sterilization Laws
Model Eugenical Sterilization Law (Laughlin, 1922) defines socially inadequate
classes
30. US Supreme Court Case
The case of Buck vs. Bell Carrie Buck
• Mother, Emma, was in asylum
• Gave birth at age 17 out of wedlock
• Daughter, Vivian, was examined at seven months and deemed feebleminded
• Charged with feeblemindedness, immorality, prostitution, and untruthfulness
• Supreme Court Ruling: “It is better for all the world, if instead
of waiting to execute degenerate offspring for crime, or to let them starve for
their imbecility, society can prevent those who are manifestly unfit from
continuing their kind…Three generations of imbeciles is enough.” – Justice
Oliver Holmes
31. Eugenics and Research
EUGENICS CLAIMED THROUGH SCIENCE THEY WERE ABLE TO IDENTIFY……
Desirables
• Emotional stability
• Strong character
• Considerateness for other people
• Intelligence
• Tendency to uphold or improve moral
standards
• The quality which makes people feel a
personal responsibility for the public
welfare
Undesirables
• Pauperism
• Alcoholism
• Feeblemindedness
• Promiscuity
• Criminality
33. Concepts in Eugenics
• Intelligence and social class
• Miscegenation (racial purity)
• Hemophilia and Huntington’s Disease
• Genetic defects
34. How they are doing it?
• Genetic screening
• Birth control
• Promotion differential birth rates
• Marriage restrictions
• Segregation (racial and mentally ill)
• Forced abortions or pregnancies
• Genocide
35. Methods of Eugenics
• Mandatory eugenics: government-mandated
• Promotional voluntary eugenics: suggested to the general population
• Private eugenics: voluntary participation
36. Genetic Testing
• Predictive testing: Polycystic kidney disease
• Fluid-filled sacs grow on kidneys, possibly other organs
• Autosomal dominant (50% chance if one parent is affected)
• Onset: 30 to 40 years, possibly earlier/later
• No cure available; life-prolonging treatment possible (dialysis or kidney
transplantation)
37. Genetic Counseling
• “An informative and supportive dialogue regarding a known, potential, or
unsuspected genetic condition.”
• Manic-depressive illness (Kay Redfield Jamison)
“To whom is the genetic counselor responsible? The
patient or married couple alone? Other family
members? Future generations who may suffer
increasing numbers of persons with genetic defects?”
Ruth Macklin, “Moral Issues in Human Genetics: Counseling or Control?”
38. Prenatal Genetic Testing
• Cystic fibrosis
• Recessive (25% chance if both parents are carriers)
• Life expectancy: 30 years
• Carrier test available to pregnant couples or those planning to become pregnant
39. Flaws of Eugenics
• Failure to recognize the complexity of human traits
• Disregard of environmental/social factors
• Skewed results
• Linking undesirable traits with racial and ethnic groups
• Disregard of effects on genetic diversity
• Flawed IQ testing
40. The Fall of Eugenics
• Mainly due to atrocities committed by Nazis
• Emerging evidence against Eugenic claims
• Reginald Punnet
• Hardy-Weinberg
• Opposition from the Church/Mosque
41. Eugenics Then and Now
• Then: Focus on selective breeding.
• Now: Focus on prenatal testing and screening, genetic counseling, birth control,
in vitro fertilization, and genetic engineering.
42. Role-Play Activity
• The Review Board has to determine a policy for the hospital
regarding whether PGD should be permitted for the following
purposes:
• to help two CF carriers avoid passing on the disease;
• to help a couple produce umbilical cord cells for an existing child with Fanconi’s
anemia;
• to help a couple select the sex of their child for “family balancing”;
• To help a short couple produce a taller child.
Editor's Notes
More than anything else, eugenics was a biological way of thinking about social, economic, political and cultural change… it gave scientific credibility… to… prejudices, anxieties, and fears that… were prevalent primarily… among the middle and upper classes.’ (Richard Soloway)
The movement began in the late 19th century with reasonable goals. Both scientists and members of the general public were interested in using their newly acquired knowledge of inheritance to work toward making improvements in the human "stock." But, with time, the eugenics movement became a tool for discriminating against and harming individuals and groups. By the end of World War II, the word "eugenics" was forever linked to acts of discrimination and extreme cruelty