The Role of Inflammatory Cytokines in Type 2 Diabetes Mellitus : Short Review
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The Role of Inflammatory Cytokines in Type 2 Diabetes Mellitus : Short Review.
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The Role of Inflammatory Cytokines in Type 2 Diabetes Mellitus : Short Review
- 1. The Role of Inflammatory Cytokines in type 2 Diabetes : Short Review B I O C H E M I S T R Y A s h o k K a t t a , A s s t . P r o f e s s o r , D e p t . o f B i o c h e m i s t r y
- 2. 2 But..we have changed from a primitive hunter- caveman to a sophisticated modern man, especially in the urban areas
- 3. Gains •Better living conditions •Variety of foods •Better transportation •Better communication Losses •More eating •Less physical activity •More stress
- 5. 5 Diabetes
- 6. 6 Diabetes: A global emergency
- 7. 7 Diabetes around the world
- 8. 8 Diabetes around the world
- 9. 9
- 10. 10 Diabetes around the world
- 11. 11 Diabetes around the world
- 12. 12 Diabetes around the world
- 13. 13
- 14. 14
- 16. 17
- 17. 18
- 18. 21
- 20. 23 Cytokines and Diabetes TNF-α and Diabetes
- 23. 26Action of TNFα
- 25. 28 IL-6 and TNF alpha deactivate IRS-2.
- 29. 33
- 30. 34 Conclusion
- 31. 36
- 32. 37
- 33. 38
Editor's Notes
- Intracellular cytokine-associated signaling pathways. JAK, Janus kinase; Tyk, Tirosine kinase; STAT, signal transducer and activator of transcription; MYD88, myeloid differentiation factor-88; IRAK, IL receptor–associated kinase; TRAF, TNF receptor–associated factor; TAK, TGF-β–associated kinase; NIK, NF-κB–inducing kinase; IKK, inhibitor of NF-κB kinase; TRADD, TNF receptor–associated death domain; RIP, receptor interacting protein; MEKK, mitogen-activated protein kinase/Erk kinase kinase; JNK, c-Jun N-terminal kinase.