SMTP is a protocol used to transfer email between servers. It uses a push protocol to send email from the sender to the receiver's email server, while POP3 or IMAP are used by the receiver to retrieve emails. SMTP uses TCP connections to transfer emails and operates using a client-server model, with SMTP servers listening for connections from SMTP clients to deliver emails. SMTP can use either an end-to-end or store-and-forward delivery method to route emails between organizations or within an organization.