This document discusses risk and protective factors for substance abuse from individual, peer, family, school, and community levels. It identifies factors such as low self-esteem, inappropriate coping skills, peer drug use, family history of drug abuse, academic failure, and drug availability as increasing risk, while bonding to pro-social values, social competence, clear family rules, school commitment, and community involvement reduce risk. The document advocates a multidisciplinary approach incorporating available community resources to prevent co-occurring disorders.
DRUG SCENARIO IN THE PHILIPPINES
*COMMON CONCEPTS IN DRUG EDUCATION
The following are the usual words you will encounter in studying substance use and abuse:
DRUGS
DRUGS OF ABUSE
DRUG DEPENDENCE
DRUG MISUSE
DRUG ABUSE
DRUG TOLERANCE
PROFILE OF DRUG ABUSERS
(Facility Based)
CY 2018
• AGE : Mean age of 32 years old
• SEX : Ratio of Male to Female (9:1)
• CIVIL STATUS : Single (51.20%)
• STATUS OF EMPLOYMENT : Unemployed (50.06%)
• EDUCATIONAL ATTAINMENT : High School Level (28.14%)
• ECONOMIC STATUS : Average Family Income Php 11,265.10
• PLACE OF RESIDENCE : Urban (specifically NCR (4.81%)
• DURATION OF DRUG USE : More than six (6) years
• NATURE OF DRUG TAKING : Mono drug use (abuse of 1 drug only)
• DRUGS/SUBSTANCES OF ABUSE :
Methamphetamine Hydrochloride (Shabu)
Cannabis (Marijuana)
Contact Cement (Rugby)
Risk and Protective Factors for Drug Use, Misuse, Abuse and Dependence (Lesso...Jewel Jem
Risk and Protective Factors for Drug Use, Misuse, Abuse and Dependence
Lesson for Grade 9 (Health) MAPEH
Contents:
> Risk & Protective Factors (meaning)
> Factors composed of influences in Life Domains
- Personal
- Family
- Peer and Friends
- School
- Community
There are many myths surrounding drug addiction, such as 'all drug users are addicts' or 'only hard drugs are dangerous'. In this slideshow, we bust these myths and provide the truth around drug addiction.
www.drugabuse.com
DRUG SCENARIO IN THE PHILIPPINES
*COMMON CONCEPTS IN DRUG EDUCATION
The following are the usual words you will encounter in studying substance use and abuse:
DRUGS
DRUGS OF ABUSE
DRUG DEPENDENCE
DRUG MISUSE
DRUG ABUSE
DRUG TOLERANCE
PROFILE OF DRUG ABUSERS
(Facility Based)
CY 2018
• AGE : Mean age of 32 years old
• SEX : Ratio of Male to Female (9:1)
• CIVIL STATUS : Single (51.20%)
• STATUS OF EMPLOYMENT : Unemployed (50.06%)
• EDUCATIONAL ATTAINMENT : High School Level (28.14%)
• ECONOMIC STATUS : Average Family Income Php 11,265.10
• PLACE OF RESIDENCE : Urban (specifically NCR (4.81%)
• DURATION OF DRUG USE : More than six (6) years
• NATURE OF DRUG TAKING : Mono drug use (abuse of 1 drug only)
• DRUGS/SUBSTANCES OF ABUSE :
Methamphetamine Hydrochloride (Shabu)
Cannabis (Marijuana)
Contact Cement (Rugby)
Risk and Protective Factors for Drug Use, Misuse, Abuse and Dependence (Lesso...Jewel Jem
Risk and Protective Factors for Drug Use, Misuse, Abuse and Dependence
Lesson for Grade 9 (Health) MAPEH
Contents:
> Risk & Protective Factors (meaning)
> Factors composed of influences in Life Domains
- Personal
- Family
- Peer and Friends
- School
- Community
There are many myths surrounding drug addiction, such as 'all drug users are addicts' or 'only hard drugs are dangerous'. In this slideshow, we bust these myths and provide the truth around drug addiction.
www.drugabuse.com
There is an epademic of cocaine and other drugs use in our schools. This presentation was created to be used at High Schools to explain and illustrate to the students about the bad affects of using drugs.
Prevention of Substance Use & Abuse (Gateway Drugs - Cigarettes)Jewel Jem
GRADE 9 Lesson on
Prevention of Substance Use & Abuse
and
Gateway Drugs (focusing on Cigarettes)
Cigarettes
Contents of Cigarettes
Risks and Other factors :)
The Dangers of Alcohol - MAPEH 8 (Health 4th Quarter)Carlo Luna
HEALTH Unit 4: Prevention of Substance Use and Abuse
Lesson 2: The Dangers of Alcohol
This material is designed to inform your students about the dangers of alcohol and teach them the various strategies to prevent substance use and abuse.
The Six Classifications of Drugs of Abuse (Grade 9 (Mapeh) Health Lesson)Jewel Jem
The Six Classifications of Drugs of Abuse
> Gateway Drugs
> Depressants
> Stimulants
> Narcotics
> Hallucinogens
> Inhalants
Along with meanings, types and pictures
The good and bad effects of each classifications of the drugs of abuse
Slide Show: Risk Factors for Alcoholism & Drug AddictionHillside
Drug and alcohol addiction develops over time, but it often comes with copious warning signs before casual use grows into full-blown addiction. Even before a person uses, there are many signs that could indicate a person is more likely to fall into abusive patterns of drug use. While risk factors don’t necessarily mean that addiction is inevitable, it’s important for individuals to be aware of their risk level so their behavior will be more informed if they choose to engage in drug use. Watch our slide show for information and statistics about drug and alcohol abuse risk factors. For more information about seeking help with addiction recovery for yourself or a loved one, contact Hillside.
There is an epademic of cocaine and other drugs use in our schools. This presentation was created to be used at High Schools to explain and illustrate to the students about the bad affects of using drugs.
Prevention of Substance Use & Abuse (Gateway Drugs - Cigarettes)Jewel Jem
GRADE 9 Lesson on
Prevention of Substance Use & Abuse
and
Gateway Drugs (focusing on Cigarettes)
Cigarettes
Contents of Cigarettes
Risks and Other factors :)
The Dangers of Alcohol - MAPEH 8 (Health 4th Quarter)Carlo Luna
HEALTH Unit 4: Prevention of Substance Use and Abuse
Lesson 2: The Dangers of Alcohol
This material is designed to inform your students about the dangers of alcohol and teach them the various strategies to prevent substance use and abuse.
The Six Classifications of Drugs of Abuse (Grade 9 (Mapeh) Health Lesson)Jewel Jem
The Six Classifications of Drugs of Abuse
> Gateway Drugs
> Depressants
> Stimulants
> Narcotics
> Hallucinogens
> Inhalants
Along with meanings, types and pictures
The good and bad effects of each classifications of the drugs of abuse
Slide Show: Risk Factors for Alcoholism & Drug AddictionHillside
Drug and alcohol addiction develops over time, but it often comes with copious warning signs before casual use grows into full-blown addiction. Even before a person uses, there are many signs that could indicate a person is more likely to fall into abusive patterns of drug use. While risk factors don’t necessarily mean that addiction is inevitable, it’s important for individuals to be aware of their risk level so their behavior will be more informed if they choose to engage in drug use. Watch our slide show for information and statistics about drug and alcohol abuse risk factors. For more information about seeking help with addiction recovery for yourself or a loved one, contact Hillside.
The video for this presentation is available on our Youtube channel:
https://youtube.com/allceuseducation A continuing education course for this presentation can be found at https://www.allceus.com/member/cart/index/index?c=
Part of the Addiction counselor training curriculum
Social Determinants and Global Health
Julius Global Health, Julius Center, University Medical Center Utrecht, The Netherlands.
For more information: www.globalhealth.eu
The historical development of Abnormal Psychology or Psychopathology is worth studying. The progressive as well as conservative steps have contributed to a balanced view of abnormal behavior.
Theories of Psychopathology
Psychoanalytic theory – Sigmund Freud
Developmental Theories
Psychosocial Stages – Erik Erikson
Cognitive Stages – Jean Piaget
Interpersonal Theories
Harry Stack Sullivan
Hildegard Peplau
Humanistic Theories
Hierarchy of Needs - Abraham Maslow
Client-centered Theory - Carl Rogers
Behavioral Theories
Classical Conditioning - Ivan Pavlov
Operant Conditioning – Burrhus F. Skinner
This course provides training and CEUs for addicitons counselors and LPCs working in Addictions, Mental Health and Co-Occurring Disorders will help counselors, social workers, marriage and family therapists, alcohol and drug counselors and addictions professionals get continuing education and certification training to aid them in providing services guided by best practices. AllCEUs is approved by the california Association of Alcohol and Drug Abuse Counselors (CAADAC), NAADAC, the Association for Addictions Professionals, the Alcohol and Drug Abuse Counseling Board of Georgia (ADACB-GA), the National Board for Certified Counselors (NBCC) and most states.
Overview of substance abuse/addiction prevention principles including risk and protective factors. NBCC, NAADAC, CAADAC, and California Board of Behavioral Sciences approved Mental Health continuing education and addictions counselor training series. Narrated versions and CEUs available at http://www.allceus.com
Reviews addiction theory, the Jellenik curve, reasons for use and risk and protective factors related to substance abuse. NBCC, NAADAC, CAADAC, and California Board of Behavioral Sciences approved Mental Health continuing education and addictions counselor training series. Narrated versions and CEUs available at http://www.allceus.com
JUVENILE
DELINQUENCY
THE CORE 5E
Chapter 10:
Drug Use and
Delinquency
Marijuana and Hashish
Marijuana
Produced from the leaves of cannabis
sativa
Hashish
Concentrated form of cannabis made of
unadulterated resin from the female plant
Main ingredient in both is tetrahydrocannabinol
(THC)
A mild hallucinogen
Most commonly used drug by teenagers
Large amounts causes distortions that produce
hallucinatory effects
Not physically addictive, but long term effects debatable
Cocaine, Crack & Heroin
Cocaine
Alkaloid derivative of the coca plant
Most powerful natural stimulant that produces euphoria, restlessness,
and excitement
It can be sniffed, snorted, or injected
Immediate feeling or rush is short lived
Crack
Processed street cocaine
Gained popularity in the mid-1980s
Relatively inexpensive
Can provide a powerful high and is highly addictive
Heroin
Most dangerous commonly abused drug
Alcohol
Drug of choice for most teenagers
64% of high school seniors reported abusing it in the past
year
70% say they have tried it
By the 12th grade, 51% reported having been drunk
Negatively impacts society
Factor in nearly half of all murders, suicides, and
accidental deaths
1.4 million drivers are arrested each year for D.U.I.
840,000 more are arrested for alcohol-related offenses
The economic cost is staggering: $185 billion lost lost
each year
Impact on Health
Long term use is linked to depression and physical
ailments, ranging from heart disease to cirrhosis of the
liver
Perceived Benefits
Reduces tension, enhances pleasure, improves social
skills, and some claim it transforms experiences for the
better
Other Drugs
Anesthetic Drugs
Central nervous system depressants
Most widely abused is phencyclidine (PCP), aka angel dust
Inhalants
Some youths inhale vapors that cause a euphoric feeling that is
followed by disorientation, slurred speech, and drowsiness
Sedatives and barbiturates
Depress the central nervous system, creating a sleeplike condition
Tranquillizers
Reduce anxiety and promote relaxation
Overuse can lead to addiction, and withdrawal can be painful and
hazardous
Other Drugs
• Hallucinogens
• Provide vivid distortions of the senses without greatly
disturbing the viewers consciousness
• Examples of common hallucinogens:
• Mescaline
• LSD
• Stimulants
• Synthetic drugs that increase blood pressure, breathing rate,
bodily activity, and elevate mood
• Methedrine is the most widely used dangerous amphetamine
• aka “meth”, “speed”, “crystal meth”
• Economic cost of meth use in the U.S. exceeds $23
billion a year
Other Drugs
Steroids
Anabolic steroids are used to gain muscle bulk and strength
Black market sales approach $1 billion annually
Cause health problems such as liver ailments, tumors, kidney
problems, sexual dysfunc ...
Robert W Ball, Service and Workforce Development,
HIV/AIDS & Related Programs (HARP)
This presentation will discuss the focus testing of the same-sex domestic violence identification tool for health and community care workers developed by the HARP Unit of Sydney South West Area Health Service. Now in its final design, the screening tool is
flexible enough to be used both within government health care settings and throughout non-government support and care organisations.
Counselor Toolbox Podcast with Dr. Dawn-Elise Snipes produces 2 episodes each week in the form of live webinars (https://allceus.com/webinar ) and offers CEUs based on the podcast at AllCEUs.com/counselortoolbox
Counselor Toolbox Podcast with Dr. Dawn-Elise Snipes produces 2 episodes each week in the form of live webinars (https://allceus.com/webinar ) and offers CEUs based on the podcast at AllCEUs.com/counselortoolbox
Counselor Toolbox Podcast with Dr. Dawn-Elise Snipes produces 2 episodes each week in the form of live webinars (https://allceus.com/webinar ) and offers CEUs based on the podcast at AllCEUs.com/counselortoolbox
Counselor Toolbox Podcast with Dr. Dawn-Elise Snipes produces 2 episodes each week in the form of live webinars (https://allceus.com/webinar ) and offers CEUs based on the podcast at AllCEUs.com/counselortoolbox
Counselor Toolbox Podcast with Dr. Dawn-Elise Snipes produces 2 episodes each week in the form of live webinars (https://allceus.com/webinar ) and offers CEUs based on the podcast at AllCEUs.com/counselortoolbox
Counselor Toolbox Podcast with Dr. Dawn-Elise Snipes produces 2 episodes each week and offers CEUs based on the podcast at AllCEUs.com/counselortoolbox
Counselor Toolbox Podcast with Dr. Dawn-Elise Snipes produces 2 episodes each week and offers CEUs based on the podcast at AllCEUs.com/counselortoolbox
Counselor Toolbox Podcast with Dr. Dawn-Elise Snipes produces 2 episodes each week and offers CEUs based on the podcast at AllCEUs.com/counselortoolbox
Counselor Toolbox Podcast with Dr. Dawn-Elise Snipes produces 2 episodes each week and offers CEUs based on the podcast at AllCEUs.com/counselortoolbox
Counselor Toolbox Podcast with Dr. Dawn-Elise Snipes produces 2 episodes each week and offers CEUs based on the podcast at AllCEUs.com/counselortoolbox
Counselor Toolbox Podcast with Dr. Dawn-Elise Snipes produces 2 episodes each week and offers CEUs based on the podcast at AllCEUs.com/counselortoolbox
Counselor Toolbox Podcast with Dr. Dawn-Elise Snipes produces 2 episodes each week and offers CEUs based on the podcast at AllCEUs.com/counselortoolbox
Counselor Toolbox Podcast with Dr. Dawn-Elise Snipes produces 2 episodes each week and offers CEUs based on the podcast at AllCEUs.com/counselortoolbox
Counselor Toolbox Podcast with Dr. Dawn-Elise Snipes produces 2 episodes each week and offers CEUs based on the podcast at AllCEUs.com/counselortoolbox
Counselor Toolbox Podcast with Dr. Dawn-Elise Snipes produces 2 episodes each week and offers CEUs based on the podcast at AllCEUs.com/counselortoolbox
Infographic is based on Counselor Toolbox Podcast which can be subscribed to on any podcast player like Apple Podcasts, Castbox or Google Play. Counseling and Social Work CEUs are available on this topic at AllCEUs.com
Infographic is based on Counselor Toolbox Podcast which can be subscribed to on any podcast player like Apple Podcasts, Castbox or Google Play. Counseling and Social Work CEUs are available on this topic at AllCEUs.com
More from Dr. DawnElise Snipes ★AllCEUs★ Unlimited Counselor Training (20)
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
2. Learning Objectives Recognize the social, political, economic, and cultural context within which addiction and substance abuse exist Basic concepts of social, political, economic, and cultural systems and their impact on drug-taking activity. Identify risk and resiliency factors that characterize individuals and groups and their living environments. The history of licit and illicit drug use. Research reports and other literature identifying risk and resiliency factors for substance use. Statistical information regarding the incidence and prevalence of substance use disorders in the general population and major demographic groups.
3. Addiction Contextual Factors Social Social supports Social skills Environment Political Economic Availability Cultural context
4. Individual Risk/Resiliency Factors RISK FACTORS Certain physical, emotional or personality traits Inherited genetic vulnerability Low self esteem Psychological disturbances Inappropriate coping responses Violence/ aggression Risk taking propensity/impulsivity Alienation and rebelliousness Rejection of pro-social values/religion Lack of peer refusal skills Early and persistent problem behaviors Early sexual activity/teen pregnancy Peer rejection in elementary grades Academic Failure Less involved in recreational, social, activities Lack of information on positive health behaviors PROTECTIVE FACTORS Knowledge regarding risks associated with substance abuse/use Negative attitudes toward substances and substance use Bonding to pro-social culture Positive relationships with adults Views parents, teachers, doctors, law enforcement officers and other adults as allies Social competence Youth involvement in alternative activities Sense of well-being/self confidence Has positive future plans
5. Peer Risk/Resiliency Factors RISK FACTORS Reinforcement of negative norms and expectations within peer group Thinks alcohol and drug use is "cool" Inappropriate sexual activity among peers Ties to deviant peers/gang involvement PROTECTIVE FACTORS Involved in substance-free activities Friends disapprove of alcohol and other drug use
6. Family Risk/Resiliency Factors RISK FACTORS Family members with a history of alcohol or other drug abuse Family members don't spend much time together Parents have trouble keeping track of teens, who they're with and where they go Lack of clear rules and consequences regarding alcohol and other drug use Parents use drugs, involve youth in their use ("Get me a beer, would you?") or tolerate use by youth Parents have trouble setting consistent expectations and limits Family conflict/abuse Loss of employment PROTECTIVE FACTORS Close family relationships Consistency of parenting Education is valued and encouraged, and parents are actively involved Copes with stress in a positive way Clear expectations and limits regarding alcohol and other drug use Encourages supportive relationships with caring adults beyond the immediate family Share family responsibilities, including chores and decision making Family members are nurturing and support each other
7. School Risk/Resiliency Factors RISK FACTORS Lack of clear expectations, both academic and behavioral Students lack commitment or sense of belonging at school High numbers of students who fail academically at school Parents and community members not actively involved PROTECTIVE FACTORS Positive attitudes toward school School bonding Regular school attendance Communicates high academic and behavioral expectations Encourages goal-setting, academic achievement and positive social development Tutoring available Positive instructional climate Provides leadership and decision making opportunities for students Fosters active involvement of students, parents and community members Sponsors substance-free events School responsive to students' needs
8. Community Risk/Resiliency Factors RISK FACTORS Alcohol/other drugs readily available Irresponsible servers and sellers Laws and ordinances are unclear or inconsistently enforced Norms are unclear or encourage use No sense of "connection" to community Neighborhood disorganization Rapid changes in neighborhood High unemployment Residents at or below the poverty level Lack of strong social institutions Lack of monitoring youths' activities Inadequate media portrayals Misleading advertising Pro-use messages PROTECTIVE FACTORS Opportunities for community involvement Community religious composition Laws are consistently enforced Informal social control Policies and norms encourage non-use Community service opportunities Resources (housing, healthcare, childcare, jobs, recreation, etc.) available Comprehensive risk focused programs available for youth Programs for parents of children and adolescents Early childhood and family support programs
9. Statistics Reading Alcohol use, heavy drinking, and binge drinking: State and National data Illicit Drug Use: Special reports Co-Occurring Disorders OAS Short Reports: Fact sheets are available on poly drug use, marijuana, "club drugs", injecting heroin use, crack cocaine, and other major drugs of abuse. Trends and prevalence in alcohol, tobacco, and illegal drug use and characteristics of drug users: Data are provided on the following: Alcohol, any illegal or nonmedical drug use, marijuana and hashish, cocaine, crack cocaine, inhalants, hallucinogens, PCP, LSD, heroin, nonmedical use of prescription drugs (stimulants, sedatives, tranquilizers, and analgesics), binge drinking, heavy alcohol use, cigarettes, and smokeless tobacco.
10. Summary A multidisciplinary approach is imperative for effective prevention of co-occurring disorders It is not yet known which R/P factors (if any) are more influential than others Community coalitions are especially effective at integrating currently available resources to increase accessibility and utilization