This document provides guidance on designing questionnaires. It discusses the different types of questions, including open-ended questions that allow free responses and closed questions that provide response options. It outlines best practices for formulating clear, unbiased questions and sequencing questions logically. The document also covers formatting questionnaires, translating them if needed, and testing the design through a review process. The overall goal is to create a questionnaire that efficiently collects accurate data to meet study objectives.