Psychopharmacology
PSYCHOPHARMACOLOGY Antipsychotics Antiparkinsonisms Antidepressants Mood stabilizers Sedative Hypnotics Medications used to treat ADHD
Principles of psychopharmacotherapy The diagnostic assessment is fundamental to our model Pharmacotherapy is insufficient for complete recovery. The phase of an illness is of critical importance in terms of the initial intervention and the duration of treatment The risks to benefit ratio must always be considered when developing a treatment strategy
Principles of psychopharmacotherapy Prior personal history of good and bad response to a specific agent usually dictates the first line of choice for a subsequent episode. It is important to target specific symptoms that serves as a marker for the underlying psychopathology. Observe the development of adverse side effects.
Indications of antipsychotics Brief psychotic disorders Schizophreniform Schizophrenia Schizoaffective Disorders Delusional disorders Psychotic mood disorders Organic psychoses
Antipsychotics Phenothiazines Aliphatic Chlorpromazine ( Thorazine 25, 50,100mg) Piperidines Thioridazine ( Melleril 50, 100mg )  Mesoridazine ( Serentil 10mg.) Piperazines Fluphenazine Perphenazine ( Trilafon 4, & 8 mg.) Trifluoperazine ( Stelazine 5 mg.)
Antipsychotics THIOXANTHENES Thiothexenes – Navane Zuclophentixol HCl – Clopixol 10, 25mg tab Zuclophentixol decanoate – Clopixol depot Zuclophentixol acetate – Clopixol Acuphase
Antipsychotics Butyrophenones Haloperidol ( Haldol, 1, 2, 5, 10 mg/tab)  ( Serenace 5, 10, 20mg/tab ) ( Serenace 5mg/ampule )
Antipsychotics Benzamides Sulpiride – Dogmatil Amisulpiride - Solian
Antipsychotics Serotonin-Dopamine Antagonists Dibenzodiazepines Clozapine - Leponex Thiobenzodiazepines Olanzapine - Zyprexa Benzothiazepines Quetiapine - seroquel Benzisoxasoles Risperidone - Risperdal Benzisothiasole piperazine Ziprasidone - Zeldox (Geodon)
Unclassified Aripiprazole Abilify – 5,10, 15mg/tab
Antiparkinsonism Biperidin HCl – Akineton 2mg. Diphenhydramine – Benadryl 50mg Amantadine – Symmetrel 100mg Benztropine mesylate – Cogentin 2mg Trihexylphenidyl HCl – Artane 2mg
Antidepressants Heterocyclics MAOI’s RIMA Dopamine Agonists SSRI SNRI
Antidepressants Heterocyclics Tricyclics Imipramine - Tofranil Clomipramine - Anafranil Tetracyclics Maprotiline - Ludiomil Dothiepine – Prothiaden Mirtazapine - Remeron
Antidepressants Monoamine Oxidase Inhibitors (MAOI ) Increases biogenic amines by inhibiting their degradation Should not be taken with foods w/ tyramine Examples Tranylcypromine ( Parnate ) Phenelzine ( Nardil ) Iproniazid ( Marsilid )
Antidepressants Reuptake Inhibitor of Monoamine Oxidase Inhibitor type A (RIMA) Moclobemide – Aurorix 150 mg Brofaromine
Antidepressants Dopamine Agonists Amineptine HCl – Survector 100mg/tab
Antidepressants Selective Serotonin Reuptake Inhibitors (SSRI) Paroxetine – Paxil, Seroxat 20/tab Fluovoxamine – Luvox, Faverin 50mg/tab Fluoxetine – Prozac 20mg/pulvules Sertraline – Zoloft 50mg/tab
Antidepressants Serotonin-Norepinephrine Reuptake Inhibitors Venlafaxine – Effexor 50mg./tab
Medications used for ADHD Stimulants Methylphenidate –(Ritalin, Metadate, Concerta, Daytrana) Amphetamine – (Adderall) Dextroamphetamine – (dexedrine, Dextrostat) Lisdexamfetamine mesylate ( vyvanse) Non stimulant Atomoxetine ( Strattera )
Mood Stabilizers Lithium carbonate – Quilonium R 450mg/tab Carbamazepine – Tegretol 200mg/tab Oxcarbazepine – Trileptal 300 & 600mg Depakene – Valproic Acid Divalproate sodium – Epival 250mg/tab
Sedative - Hypnotics Benzodiazepines Imidazopyridines Cyclopyrrolone derivatives
Benzodiazepines Estazolam Lorazepam Clobazam Clorazepate dipotassium alprazolam Clonazepam Flurazepam Triazolam Midazolam Diazepam Short-acting Intermediate Long Acting
Imidazopyridines Zolpidem – Stilnox 10mg/tab  Ambien in US
Cyclopyrrolone derivative Zopiclone – Imovane 7.5mg/tab

Psychopharmacology