This document provides information about a normal newborn, including circulatory changes at birth, lung changes, carbohydrate metabolism, temperature regulation, and essential newborn care. It discusses assessment of gestational age, physical examination of the newborn, and neonatal immunization in Singapore. The key points are circulatory adaptation to extrauterine life, lung fluid reabsorption, temperature regulation, glucose level changes, screening for malformations, danger signs, and the neonatal immunization schedule in Singapore.
It can be useful to evaluate practical skill competence of students, teachers, professionals, self evaluation, staff nurses, etc, in performing postnatal assessment
It can be useful to evaluate practical skill competence of students, teachers, professionals, self evaluation, staff nurses, etc, in performing postnatal assessment
This topic contains detail information about all abnormalities during puerperium like puerperial pyrexia, sepsis, subinvolution, breast complications, urinary complications, puerperal venous thrombosis, pulmonary embolism, obstetric palsies, puerperal emergencies, psychiatric disroders, perinatal management
Normal newborn care, by Dr Amal Khalil, Dean of Nursing college, Port said University, Port said. Presented in the NICU nursing workshop, organized by Nursing syndicate in Suez canal & Sinai in cooperation with Port said university college of nursing & Port said neonatology society, December,2014 Port said
This topic contains detail information about all abnormalities during puerperium like puerperial pyrexia, sepsis, subinvolution, breast complications, urinary complications, puerperal venous thrombosis, pulmonary embolism, obstetric palsies, puerperal emergencies, psychiatric disroders, perinatal management
Normal newborn care, by Dr Amal Khalil, Dean of Nursing college, Port said University, Port said. Presented in the NICU nursing workshop, organized by Nursing syndicate in Suez canal & Sinai in cooperation with Port said university college of nursing & Port said neonatology society, December,2014 Port said
Growth of the fetus begins soon after fertilization, when the first cell division occurs.
Cell division, hypertrophy, and differentiation are highly coordinated events that result in the growth and development of specialized organ systems.
The fetus, fetal membranes, and placenta develop and function as a unit throughout pregnancy, and their development is interdependent or symbiotic.
The growth trajectory of fetal mass is relatively flat during the first trimester, increases linearly at the beginning of the second trimester, and rises rapidly during the third trimester.
Neonatal and Pediatric Critical Care - Mostafa QalavandWang Lang
Neonatal and pediatric critical care is markedly different from adult critical care because of the physiologic and hemodynamic dissimilarities between immature and adult animals. Clinicians are often wary of treating these patients because of their small size and the presumptive limitations in diagnostic and therapeutic interventions. Nevertheless, we have the ability to treat these young animals aggressively. In doing so, however, we must be cognizant of the unique distinctions among pediatric patients with regard to normal physiologic variables that affect physical examination findings and diagnostic test results.
This is the first part of my Neonatology Powerpoint series.
It comprises an illustrative demonstrations of:-
Introduction to neonatology.
The APGAR score
General are of the newborn.
Neonatal examination & assessment.
Approach to cardiac murmurs and cardiac examination in childrenVarsha Shah
Cardiovascular examination in children for MBBS undergraduate, Residents, Trainees, pediatricians, GP, family physicians, nursing , dental, allied health students
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Best Ayurvedic medicine for Gas and IndigestionSwastikAyurveda
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Basavarajeeyam - Ayurvedic heritage book of Andhra pradesh
Normal newborn final
1. Normal Newborn
Dr Varsha Atul Shah
Consultant
Dept. of Neonatal& Dev Medicine
Singapore General Hospital
2. Newborn Adaptation At Birth
o Circulatory changes (gas exchange from placenta to the lungs)
g Reabsorption of fetal lung fluid
f Closure of patent ductus arteriosus
t Stabilization of cardiac rhythm
Establishment of regular breathing
Temperature regulation
l Changes in carbohydrate metabolism
3. Circulatory changes
g Reduction of pulmonary vascular resistance, increased PBF by
10 folds
m Increase in left atrial pressure
Closes foramen ovale
v Increase systemic vascular resistance
c Rt to lt flow at PDA diminishes, closes PDA
PS: failure to achieve reduce PVR cause PPHN
8. Lung changes
Lung fluid absorption (failure cause TTNB, Transient
Tachypnea of Newborn)
b RR rises to 60/min
i Transient grunting, mild retraction, ala nasi flare may
be seen
9. Carbohydrate Metabolism
a Cessation of maternal glucose supply
e Decline in glucose level by 2 hrs
s 20-30% CHO comes from milk
Gluconeogenesis from AA, glycerol, lactate
10. Temperature regulation
l Low ambient temp, evaporation, radiation, convection,
conduction loss of heat –Hypothermia
o Achieve Neutral thermal environment
t Drying, swaddling, skin-skin contact, radiant warmer, leave
vernix, wrapping, early feeding
11. Immediate care after birth
Prevent hypothermia
Eye, skin, cord care
Give injection vitamin K
Breastfeed within ½ hour of birth
Search for malformations
12. Increased risk of malformation
Single umbilical artery
Simian crease
Dysmorphic features
Asymmetric cry due to absence of Depressor
Angularis Oris Muscle
Excessive drooling of saliva
13. Quick screening for malformations
Screen from top to bottom and in midline
Orifice examination
– Anal opening
– Oesophagus patency*
– Choanal atresia
– * SGA baby, polyhydramnios, excessive drooling,
• single umbilical artery
14. Essential postnatal care
Nurse in thermal comfort
(warm to touch, pink soles)
Check umbilicus, skin, eyes
Good sucking at breast
Screen for danger signals
Advice on immunization
15. Care of umbilical stump
Inspect 2 to 4 hours after ligation for bleeding
Do not apply anything, keep cord
clean and dry
Inspect for discharge or infection till healing
occurs
16. Care of the skin
Dry using soft prewarmed clean cloth
Bathing soon after birth is not
recommended
Do not make vigorous attempts to
remove vernix caseosa
Inspect for superficial infections
17. Care of the eyes
Clean at birth and subsequently daily
For sticky eyes use normal saline or appropriate
medication
u Nasolacrimal duct blockage, Massaging helps
18. Danger signs
Lethargy r Bleeding
Hypothermia r Yellow palms/ sole
Respiratory distress l Excessive wt loss
r Cyanosis s Vomiting
r Convulsions s Diarrhoea
r Abd distension
19. Infant Classification
-by Gestational Age
ATerm : 37-41+6/7 weeks
Preterm: <37 weeks
k Post-term: 42 or more weeks
20. Infant Classification
-by birthweight
a Macrosomia: 4000 gm or more
Normal birthweight: 2500-3999 gm
h Low birthweight: <2500 gm
Very low birthweight: <1500 gm
i Extremely low birthweight: <1000 gm
21. Term infant
A well term infant loses up to 10% of birth weight in
the first week of life;
f Birth weight is regained by 10-14 day and thereafter
gains 30g/day.
r His caloric intake/requirement is 100-120 kcal/kg/day
k with 2-5 g/kg/day of protein for cellular growth.
22. Infant Classification
-by Gestational Sizes
S Appropriate for gestational age
g Large for gestational age
i Small for gestational age
i classify based on maturity
and intrauterine growth
PS:Energy stores in the fetus builds up mostly
during the 3rd trimester of the pregnancy.
23. Gestational Age Assessment
A Maternal dates
S Early Ultrasound dating
Dates of first recorded fetal activity
e Dates of first recorded fetal heart sounds
e Dubowitz or Ballard scores
26. Physical Examination
of the Newborn
t Purpose
- detect malformations or deformations
- determine manifestations of various neonatal
diseases
- evaluate the effects of labour and delivery
on newborn
27. Physical Examination
t General appearance
- cyanosis, nasal flaring, intercostal retractions, grunting, meconium staining
of skin, perfusion, level of spontaneous activity, tone, cry
Vital signs
- HR (120-160 beats/min), RR (30-60 breaths/min), To, b/p, Wt, length and
OFC In term healthy infants, the core temperature will fall after birth by about
0.8-2 degrees Celsius.
l Gestational age assessment
28. Physical Examination
t Skin
- harlequin color change, hair tufts, mongolian spots, naevus
flammus, malia malenocytic naevus, haemangiomas, pustular
melanosis, erythema toxicum
e Skull
- cranial synostosis, fontanels, craniotabes, caput
succedaneum, subgaleal hemorrhage
44. Milky white or blood-streaked vaginal
discharge is the result of maternal
hormone withdrawal.
45. Physical Examination
t Hip assessment
- Barlow test, Ortolani manoeuver to determine whether femoral head
can be displaced from acetabulum and replaced respectively
Neurologic assessment
- tone, alterness, primitive reflexes (Moro’s, palmar grasp, rooting
reflex), deep tendon reflexes, spontaneous motor activity, cranial nerves