Inorganic Non-Metallic Irritants, poisoning

1. Dr Mohd Kaleem Khan
Assistant Professor
Department Of Forensic Medicine
JNMCH AMU Aligarh

2.  It exists in two varieties:
◦ White/ yellow phosphorus
 Fertilizers, insecticide, rodenticide, incendiary bombs, smoke
screens, firework
◦ Red phosphorus
 matchbox

3. Red phosphorus White phosphorus
 Violet red/ reddish
brown
 Amorphous, solid
mass
 odourless, tasteless
 Non luminescent
 Soluble in carbon
disulphide
 Non toxic
 Does not ignite in air
 White or yellow
 Waxy, translucent, soft
stick
 Garlicky taste and
odour
 Luminescent in dark
 Insoluble
 Highly toxic
 May ignite in air

4. ◦ Protoplasmic poison
◦ Affect cellular oxidation
◦ Causes necrobiosis especially of liver ( yellow atrophy of
liver) and kidneys
◦ Causes bone formation in epiphysial cartilage and haversian
canal

5.  First stage(0.5-6 hr)
◦ Skin: painful penetration, second and third degree burn.
◦ Ingestion :
 Nausea, vomiting , diarrhoea, thirst,
 Burning pain in throat and abdomen,
 Garlicky odour in breath, vomitus and faeces,
 Luminescent smoking urine and faeces

6.  Symptoms second stage( after 2-3 days)
 Severe abdominal pain
 Nausea, vomiting, haematemesis, diarrhoea
 Tender hepatomegaly, jaundice, pruritis
 Oliguria, haematuria, albuminuria
 Headache, insomnia, convulsions, coma
 Carpopedal spasm, tetany, stridor, opisthotonus
 Purpura, epistaxis
 Death d/t cardiac dysrythmias, hypocalcemia and hyperkalemia.

7.  F.D.: 60- 120 mg
 F.P. : 24 hrs

8. ◦ Airway support and fluid maintenance
◦ External burns
◦ Gastric lavage: KMNO4 ( antidote), charcoal
◦ Demulscents are contraindicated
◦ Purgatives
◦ Vit K or blood transfusion
◦ Haemodialysis
◦ N acetylcystein, ubiquinon and sulphate to prevent liver
damage

9. ◦ Emacition, purpura, jaundice and garlicky odour
◦ Hypostasis dark brown in colour
◦ Liver is soft , swollen, fatty and easily ruptured
◦ Kidney; enlarged greasy and yellow

10. ◦ Accidental
◦ Homicidal
◦ Criminal abortion
◦ Arson

11. ◦ Necrosis of jaw in region of decayed tooth
◦ Phossy jaw: toothache, swelling of jaw, loosening of teeth,
necrosis of gums and sequestration of bone with multiple
sinuses discharging foul smelling pus
◦ nausea, vomitig , diarrhoea, thirst, burning pain in throat and
abdomen, joint pain, jaundice, ascitis, anaemia