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DR MOHD KALEEM KHAN
ASSISTANT PROFESSOR
DEPARTMENT OF FORENSIC MEDICINE
JNMCH AMU ALIGARH
DRUG ADDICTION
AND
DRUG ABUSE
Drug dependence
 Is a condition results from repeated consumption of
a drug characterized by
 Increased desire to take the drug.
 Increasing dose to get the desired effect
 An increasing effort to collect it.
 Causing physical and psychological dependence
 It includes both the terms
 Addiction
 Habituation
Drug addiction and drug abuse
 Addiction is a state of periodic or
chronic intoxication, produced by the
 Repeated consumption of a drug,
 Harmful to individual and society.
 Alcohol, cannabis and heroin are the most
commonly abused substances in the world.
 Physical Dependence is a biological phenomenon
which depends on the type, dose, and duration of
drug use irrespective of the personnel factors and
associated with withdrawal syndrome
 Psychological Dependence(drug Habituation) is a
condition resulting from the repeated consumption
of a drug, in which there is a psychological or
emotional dependency. Caffeine and nicotine are
most common habit forming drugs.
Drug use terms and descriptions
 Drug:

 In medicine, it refers to any substance with the
potential to prevent or cure disease or enhance
physical or mental well-being.
 In pharmacology, drug refers to any agent that
alters the biochemical or physiological
processes of tissue or organism.
 Street drug: Drug that is taken for non-medicinal
reasons (usually for mind-altering effects); drug
abuse can lead to physical and mental damage and
(with some substances) dependence and addiction.
Eg: Alcohol, heroin, methamphetamine, crack,
cocaine and marijuana
Drug use terms and descriptions
 Hard drug (lead to severe physical addiction):
– Drug that is generally considered to be more
dangerous, with a higher risk of dependence
that soft drugs. Eg.: Heroin, methamphetamine,
cocaine.
 Soft drug (do not cause physical addiction): –
While they do not cause physical addiction,
some of them may still lead to psychological
dependency.
 Psychological dependency is a dependency of the
mind. This means that people feel better when they
have the drug. Eg: lysergic acid diethylamide
(LSD), Cannabis
Drug use terms and descriptions
 Illicit drug: AN illegal drug, can’t prescribed. Eg.:
Cocaine, heroin, LSD, marijuana.
 Designer drug: A synthetic drug very similar in
chemical makeup to an existing drug and thus exerting
similar.
 Club drug: A drug whose use primarily occurs in
clubs, bars and trance parities. E.g: Rohypnol,
ketamine.
 Recreational drugs: – Recreational drugs are those
used for non medicinal purposes, in particular, for
fun or leisure. – Eg.: methamphetamine (potent
psychostimulant of the phenethylamine), that is used
to treat attention deficit hyperactivity disorder
(ADHD), drive long distances and obesity
Drug use terms and descriptions
 Adulterants: drugs that are added to mimic
or enhance the effects of the drug being
offered. Example, sometimes amphetamines
have been cut with caffeine or ephedrine.
 Diluents: Compounds such as sugars or
baking soda that are used to increase the
bulk of the drug sample.
Types of Abused Substances
 Legal Substances – Legal substances, approved by law
for sale over the counter or by doctor's
prescription, include caffeine, alcoholic beverages,
nicotine, and inhalants (nail polish, glue,
inhalers, gasoline).
 Prescription drugs such as tranquilizers,
amphetamines, benzodiazepines, barbiturates,
steroids, and analgesics can be knowingly or
unknowingly overprescribed or otherwise used
improperly.
Types of Abused Substances
 Illegal Substances – Prescription drugs are
considered illegal when diverted from proper use. –
Morphine, and synthetic opiates, such as fentanyl,
are most often abused by people in the medical
professions, who have easier access to these drugs.
 Other illegal substances include cocaine and crack,
marijuana and hashish, heroin, hallucinogenic drugs
such as lysergic acid diethylamide, phencycline or
"angel dust", "designer drugs" such as MDMA
(Ecstasy), and "party drugs" such as GHB (gamma
hydroxybutyrate).
Motivations for Drug Use
 People take drugs for many reasons, and they may
take

 Stimulants to keep alert, or
 Cocaine for the feeling of excitement it produces. –
Peer pressure – relief of stress – increased energy – to
relax – to relieve pain – to escape reality – to feel more
self-esteem, and for recreation. •
 Athletes and bodybuilders may take anabolic steroids
to increase muscle mass
 Effects of substance abuse • the effects of
substance abuse can be on many levels: – on the
individual, – on friends and family, – on
society.
Effects of Substance Abuse-
 Criminal activity, such as burglary and prostitution, to
raise the money to buy drugs, and some drugs, especially
alcohol, are associated with violent behaviour.
 Cocaine: anxiety, fatigue, depression, and an acute desire.
 Marijuana and alcohol interfere with motor control and are
factors in many automobile accidents.
 Users of marijuana and hallucinogenic drugs may experience
flashbacks, unwanted recurrences of the drug's effects weeks
or months after use.
 Sharing hypodermic needles - aids and hepatitis.
 Heroin withdrawal can cause vomiting, muscle cramps,
convulsions, and delirium.
Effects of Substance Abuse
 Marital problems and poor work performance.
 Pregnant drug users, because of the drugs
themselves or poor self-care in general,
bear a much higher rate of low birth-weight
babies than the average.
 In the workplace it is costly in terms of
lost work time and inefficiency.
 Drug-related crime can disrupt neighborhoods
due to violence among drug dealers, threats
to residents, and the crimes of the addicts
themselves.
Symptoms
 Failure to fulfil major role obligations at work, school,
or home.
 Poor performance, suspensions, or neglect of duties.
 Sign of abuse.
 Walking in a dangerous area while under the influence
indicates drug abuse.
 Recurrent drug-related legal problems, such as arrests
 Persistent or recurrent social or interpersonal problems,
caused or exacerbated by the effects of the drug,.
Treatment
 Treatment of substance abusers depends upon the
severity and nature of the addiction, motivation,
and the availability of services.
 Pharmacological treatment •
 Fighting Substance Abuse •
 Supply Reduction •
 Reduction of demand for drugs •
 Legalization and decriminalization
Treatment
 Pharmacotherapy • Both pharmacological and behavioural
treatments are used, often augmented by educational and
vocational services.
 Treatment may include detoxification, therapy, and
support groups, such as the 12-step groups Alcoholics
Anonymous, Narcotics Anonymous, and Cocaine Anonymous.
 – Disulfiram is a medicine used in the treatment of
alcoholism.
 – methadone or buprenorphine maintenance programs for heroin
addiction.
 The main drugs of abuse Type Examples Dependence
liability Narcotic analgesics Morphine Very strong
Diamorphine Very strong General CNS depressants Ethanol
Strong Barbiturates Strong Methaqualone Moderate
Glutethimide Moderate Anaesthetics Moderate Solvents
Strong
 The main drugs of abuse (continued) Anxiolytic drugs
Benzodiazepines Moderate Psychomotor stimulants
Amphetamines Strong Cocaine Very strong Caffeine Weak
Nicotine Very strong Psychotomimetic agents LSD Weak or
absent Mescaline Weak or absent Phencyclidine Moderate
Cannabis Weak or absent

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Drug addiction a& dependence

  • 1. DR MOHD KALEEM KHAN ASSISTANT PROFESSOR DEPARTMENT OF FORENSIC MEDICINE JNMCH AMU ALIGARH DRUG ADDICTION AND DRUG ABUSE
  • 2. Drug dependence  Is a condition results from repeated consumption of a drug characterized by  Increased desire to take the drug.  Increasing dose to get the desired effect  An increasing effort to collect it.  Causing physical and psychological dependence  It includes both the terms  Addiction  Habituation
  • 3. Drug addiction and drug abuse  Addiction is a state of periodic or chronic intoxication, produced by the  Repeated consumption of a drug,  Harmful to individual and society.  Alcohol, cannabis and heroin are the most commonly abused substances in the world.
  • 4.  Physical Dependence is a biological phenomenon which depends on the type, dose, and duration of drug use irrespective of the personnel factors and associated with withdrawal syndrome  Psychological Dependence(drug Habituation) is a condition resulting from the repeated consumption of a drug, in which there is a psychological or emotional dependency. Caffeine and nicotine are most common habit forming drugs.
  • 5. Drug use terms and descriptions  Drug:   In medicine, it refers to any substance with the potential to prevent or cure disease or enhance physical or mental well-being.  In pharmacology, drug refers to any agent that alters the biochemical or physiological processes of tissue or organism.  Street drug: Drug that is taken for non-medicinal reasons (usually for mind-altering effects); drug abuse can lead to physical and mental damage and (with some substances) dependence and addiction. Eg: Alcohol, heroin, methamphetamine, crack, cocaine and marijuana
  • 6. Drug use terms and descriptions  Hard drug (lead to severe physical addiction): – Drug that is generally considered to be more dangerous, with a higher risk of dependence that soft drugs. Eg.: Heroin, methamphetamine, cocaine.  Soft drug (do not cause physical addiction): – While they do not cause physical addiction, some of them may still lead to psychological dependency.  Psychological dependency is a dependency of the mind. This means that people feel better when they have the drug. Eg: lysergic acid diethylamide (LSD), Cannabis
  • 7. Drug use terms and descriptions  Illicit drug: AN illegal drug, can’t prescribed. Eg.: Cocaine, heroin, LSD, marijuana.  Designer drug: A synthetic drug very similar in chemical makeup to an existing drug and thus exerting similar.  Club drug: A drug whose use primarily occurs in clubs, bars and trance parities. E.g: Rohypnol, ketamine.  Recreational drugs: – Recreational drugs are those used for non medicinal purposes, in particular, for fun or leisure. – Eg.: methamphetamine (potent psychostimulant of the phenethylamine), that is used to treat attention deficit hyperactivity disorder (ADHD), drive long distances and obesity
  • 8. Drug use terms and descriptions  Adulterants: drugs that are added to mimic or enhance the effects of the drug being offered. Example, sometimes amphetamines have been cut with caffeine or ephedrine.  Diluents: Compounds such as sugars or baking soda that are used to increase the bulk of the drug sample.
  • 9. Types of Abused Substances  Legal Substances – Legal substances, approved by law for sale over the counter or by doctor's prescription, include caffeine, alcoholic beverages, nicotine, and inhalants (nail polish, glue, inhalers, gasoline).  Prescription drugs such as tranquilizers, amphetamines, benzodiazepines, barbiturates, steroids, and analgesics can be knowingly or unknowingly overprescribed or otherwise used improperly.
  • 10. Types of Abused Substances  Illegal Substances – Prescription drugs are considered illegal when diverted from proper use. – Morphine, and synthetic opiates, such as fentanyl, are most often abused by people in the medical professions, who have easier access to these drugs.  Other illegal substances include cocaine and crack, marijuana and hashish, heroin, hallucinogenic drugs such as lysergic acid diethylamide, phencycline or "angel dust", "designer drugs" such as MDMA (Ecstasy), and "party drugs" such as GHB (gamma hydroxybutyrate).
  • 11. Motivations for Drug Use  People take drugs for many reasons, and they may take   Stimulants to keep alert, or  Cocaine for the feeling of excitement it produces. – Peer pressure – relief of stress – increased energy – to relax – to relieve pain – to escape reality – to feel more self-esteem, and for recreation. •  Athletes and bodybuilders may take anabolic steroids to increase muscle mass  Effects of substance abuse • the effects of substance abuse can be on many levels: – on the individual, – on friends and family, – on society.
  • 12. Effects of Substance Abuse-  Criminal activity, such as burglary and prostitution, to raise the money to buy drugs, and some drugs, especially alcohol, are associated with violent behaviour.  Cocaine: anxiety, fatigue, depression, and an acute desire.  Marijuana and alcohol interfere with motor control and are factors in many automobile accidents.  Users of marijuana and hallucinogenic drugs may experience flashbacks, unwanted recurrences of the drug's effects weeks or months after use.  Sharing hypodermic needles - aids and hepatitis.  Heroin withdrawal can cause vomiting, muscle cramps, convulsions, and delirium.
  • 13. Effects of Substance Abuse  Marital problems and poor work performance.  Pregnant drug users, because of the drugs themselves or poor self-care in general, bear a much higher rate of low birth-weight babies than the average.  In the workplace it is costly in terms of lost work time and inefficiency.  Drug-related crime can disrupt neighborhoods due to violence among drug dealers, threats to residents, and the crimes of the addicts themselves.
  • 14. Symptoms  Failure to fulfil major role obligations at work, school, or home.  Poor performance, suspensions, or neglect of duties.  Sign of abuse.  Walking in a dangerous area while under the influence indicates drug abuse.  Recurrent drug-related legal problems, such as arrests  Persistent or recurrent social or interpersonal problems, caused or exacerbated by the effects of the drug,.
  • 15. Treatment  Treatment of substance abusers depends upon the severity and nature of the addiction, motivation, and the availability of services.  Pharmacological treatment •  Fighting Substance Abuse •  Supply Reduction •  Reduction of demand for drugs •  Legalization and decriminalization
  • 16. Treatment  Pharmacotherapy • Both pharmacological and behavioural treatments are used, often augmented by educational and vocational services.  Treatment may include detoxification, therapy, and support groups, such as the 12-step groups Alcoholics Anonymous, Narcotics Anonymous, and Cocaine Anonymous.  – Disulfiram is a medicine used in the treatment of alcoholism.  – methadone or buprenorphine maintenance programs for heroin addiction.
  • 17.  The main drugs of abuse Type Examples Dependence liability Narcotic analgesics Morphine Very strong Diamorphine Very strong General CNS depressants Ethanol Strong Barbiturates Strong Methaqualone Moderate Glutethimide Moderate Anaesthetics Moderate Solvents Strong  The main drugs of abuse (continued) Anxiolytic drugs Benzodiazepines Moderate Psychomotor stimulants Amphetamines Strong Cocaine Very strong Caffeine Weak Nicotine Very strong Psychotomimetic agents LSD Weak or absent Mescaline Weak or absent Phencyclidine Moderate Cannabis Weak or absent