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Vijay kumar
Language is the ability to encode ideas into signals 
which will be streamed as speech. 
It is one of the important cognitive ability humans 
have. 
Language is different from thinking or thought. 
It involves usage of words which links sounds to the 
meaning.
Syntax : rules for combining words into phrases and 
sentences & determining relations among words. 
Phonology : rules combining sounds into a consistent 
pattern in language. 
Grammer: system specifying how vocabulary units 
can be combined into words,phrases & sentences .
Descartes gave his description on language 1637 
Meynert, Hughling jackson 
Paul broca – Broca’s motor speech area 1861 
Carl Wernicke – Wernicke’s area for comprehension 
in 1874. 
Noam chomsky – Father of modern linguistics.
Marc D. Hauser et al Science 298,(2002) 
.
Marc D. Hauser et al Science 298,(2002) 
.
Language implementation system: 
- Broca’s area (Broadmann area no 44) 
- Wernicke’s area(Broadmann area no 22) 
- Insular cortex 
- Basal ganglia 
Mediational system: 
Regions in temporal ,parietal & frontal association 
cortices. 
Conceptual system: Higher order association cortices.
Marc D. Hauser et al Science 298,(2002) 
.
Angela D. Friederici, Trends in Cognitive Sciences 2009
Lesion studies done by Broca and Wernicke helped to 
identify the centers of language. 
Later critical analysis of patients using new 
techniques changed this view. 
Sign language also stimulates the same brain areas 
which are stimulated by verbal stimuli.
Left cerebral hemisphere is dominant in right handed 
individual. 
Right cerebral hemisphere is for colouring of language 
i.e. adding of emotional intonation for spoken words. 
Language centers are more prominent in left 
hemisphere.
Arcuate fasciculus was the only link between 
Wernicke’s area & Broca’s area. 
Due to Functional MRI, MEG,Diffusion tensor imaging 
tractography neural networks involved in language 
processing can be dileneated.
Dorothee Saur et al, PNAS 2008
Dorsal stream: Responsible for repetition of speech. 
Ventral stream: Listening to meaningful speech 
Gregory Hickok Phys Life Rev. 2009
Dorothee Saur et al, PNAS 2008
Linguistic genes: 
FOXP2 gene mutation in KE family with Specific 
language impairment. 
Quantitative trait loci – set of genes which are critical 
for language function. 
Critical period for language acquisition: 
Time window during which proper input signals are 
necessary for activation of the genetic programs 
underlying the normal development of brain 
structures and their functions. 
Yuri I. Arshavsky, Brain research review 2009
At birth infants exhibits a universal capacity to detect 
differences b/w phonetic contrasts used in world’s 
language. 
Native language phonetic abilities significantly 
increase. 
Infants make language like sounds at 5-7 months 
Babble in syllables at 7-8 months 
Patricia Kuhl et al Annu. Rev. Neurosci. 2008
Form sentence like streams by first year. 
By the end of first year infant brain is primed for 
language which it is exposed. 
First words are spoken around first birthday. 
Patricia Kuhl et al Annu. Rev. Neurosci. 2008
Patricia Kuhl et al Annual. Rev. Neurosci. 2008
Definition: 
Aphasias are language 
disorders which are 
caused by focal brain 
lesions due to stroke or 
head injury. 
Medical physiology, Ganong 22 nd edition
Principles of neuroscience,4th edi ,Kandel
Principles of neuroscience,4th edi ,Kandel
Principles of neuroscience,4th edi ,Kandel
Thank you

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Neurophysiology of language

  • 2. Language is the ability to encode ideas into signals which will be streamed as speech. It is one of the important cognitive ability humans have. Language is different from thinking or thought. It involves usage of words which links sounds to the meaning.
  • 3. Syntax : rules for combining words into phrases and sentences & determining relations among words. Phonology : rules combining sounds into a consistent pattern in language. Grammer: system specifying how vocabulary units can be combined into words,phrases & sentences .
  • 4. Descartes gave his description on language 1637 Meynert, Hughling jackson Paul broca – Broca’s motor speech area 1861 Carl Wernicke – Wernicke’s area for comprehension in 1874. Noam chomsky – Father of modern linguistics.
  • 5. Marc D. Hauser et al Science 298,(2002) .
  • 6. Marc D. Hauser et al Science 298,(2002) .
  • 7. Language implementation system: - Broca’s area (Broadmann area no 44) - Wernicke’s area(Broadmann area no 22) - Insular cortex - Basal ganglia Mediational system: Regions in temporal ,parietal & frontal association cortices. Conceptual system: Higher order association cortices.
  • 8. Marc D. Hauser et al Science 298,(2002) .
  • 9. Angela D. Friederici, Trends in Cognitive Sciences 2009
  • 10. Lesion studies done by Broca and Wernicke helped to identify the centers of language. Later critical analysis of patients using new techniques changed this view. Sign language also stimulates the same brain areas which are stimulated by verbal stimuli.
  • 11. Left cerebral hemisphere is dominant in right handed individual. Right cerebral hemisphere is for colouring of language i.e. adding of emotional intonation for spoken words. Language centers are more prominent in left hemisphere.
  • 12. Arcuate fasciculus was the only link between Wernicke’s area & Broca’s area. Due to Functional MRI, MEG,Diffusion tensor imaging tractography neural networks involved in language processing can be dileneated.
  • 13. Dorothee Saur et al, PNAS 2008
  • 14. Dorsal stream: Responsible for repetition of speech. Ventral stream: Listening to meaningful speech Gregory Hickok Phys Life Rev. 2009
  • 15. Dorothee Saur et al, PNAS 2008
  • 16. Linguistic genes: FOXP2 gene mutation in KE family with Specific language impairment. Quantitative trait loci – set of genes which are critical for language function. Critical period for language acquisition: Time window during which proper input signals are necessary for activation of the genetic programs underlying the normal development of brain structures and their functions. Yuri I. Arshavsky, Brain research review 2009
  • 17. At birth infants exhibits a universal capacity to detect differences b/w phonetic contrasts used in world’s language. Native language phonetic abilities significantly increase. Infants make language like sounds at 5-7 months Babble in syllables at 7-8 months Patricia Kuhl et al Annu. Rev. Neurosci. 2008
  • 18. Form sentence like streams by first year. By the end of first year infant brain is primed for language which it is exposed. First words are spoken around first birthday. Patricia Kuhl et al Annu. Rev. Neurosci. 2008
  • 19. Patricia Kuhl et al Annual. Rev. Neurosci. 2008
  • 20. Definition: Aphasias are language disorders which are caused by focal brain lesions due to stroke or head injury. Medical physiology, Ganong 22 nd edition

Editor's Notes

  1. Spotted dog biting a man….the dog bit a man…a dalmation attacked gentleman… stuffy nose can be stuff he knows…
  2. Example of wild children…specific language impairment