Major depressive disorder and childhood bipolar disorder can present with a variety of symptoms beyond just depressed mood. Assessment of these conditions requires evaluating potential comorbidities, social contexts, relationships, and risk factors. Treatment may involve antidepressant medication, psychotherapy like CBT, and monitoring for several months. Bipolar disorder in particular can be hard to diagnose in children due to overlapping symptoms with other conditions.
Introduction to Depressive Disorders in Children and AdolescentsStephen Grcevich, MD
This is the slide set to the lectures I provided to the medical staff of Child and Adolescent Behavioral Health in Canton, OH during the Fall-Winter of 2018
Depression In Children: Behavioral Manifestations and InterventionDavid Songco
Presentation delivered to the West Side Health Authority. This presentation was attended by program developers, teachers, principals, and directors of local community organizations.
Introduction to Depressive Disorders in Children and AdolescentsStephen Grcevich, MD
This is the slide set to the lectures I provided to the medical staff of Child and Adolescent Behavioral Health in Canton, OH during the Fall-Winter of 2018
Depression In Children: Behavioral Manifestations and InterventionDavid Songco
Presentation delivered to the West Side Health Authority. This presentation was attended by program developers, teachers, principals, and directors of local community organizations.
What is Oppositional Defiant Disorder - InfographicLiahona Academy
Some teens just don't want to listen. Sometimes as parents it is hard to understand why teen are just troublesome and defiant. There are many teens that could have Oppositional Defiant Disorder, could your teen have troubles with authority. Infographic presented by Liahona Academy. Find out how to help your teen boy with ODD at http://www.liahonaacademy.com/
A brief discussion about Neurocognitive disorders.
NCD are on the rise especially due to the ageing population and good treatment modalities leading to less mortality.
The burden of NCD is to increase with time especially due to the little interventions available
What is Oppositional Defiant Disorder - InfographicLiahona Academy
Some teens just don't want to listen. Sometimes as parents it is hard to understand why teen are just troublesome and defiant. There are many teens that could have Oppositional Defiant Disorder, could your teen have troubles with authority. Infographic presented by Liahona Academy. Find out how to help your teen boy with ODD at http://www.liahonaacademy.com/
A brief discussion about Neurocognitive disorders.
NCD are on the rise especially due to the ageing population and good treatment modalities leading to less mortality.
The burden of NCD is to increase with time especially due to the little interventions available
This PowerPoint is one small part of the Taxonomy and Classification unit from www.sciencepowerpoint.com. A 3800+ slide Five Part PowerPoint presentation becomes the roadmap for an amazing and interactive science experience full of built-in lab activities, built-in quizzes, video links, class notes(red slides),review games, projects, unit notes, answer keys, and much more. Also included is a student version of the unit that is much like the teachers but missing the answer keys, quizzes, PowerPoint review games, hidden box challenges, owl, and surprises meant for the classroom. This is a great resource to distribute to your students and support professionals. The Classification and Taxonomy Unit covers topics associated with Taxonomy and Classification. The unit examines all of the Kingdoms of Life in detail. Areas of Focus within The Taxonomy and Classification Unit: -Taxonomy, Classification, Need for Taxonomy vs. Common Names, What is a Species?, Dichotomous Keys, What does Classification Use?, The Domains of Life, Kingdoms of Life,The 8 Taxonomic Ranks, Humans Taxonomic Classification, Kingdom Monera, Prokaryotic Cells, Types of Eubacteria, Bacteria Classification, Gram Staining,Bacterial Food Borne Illnesses, Penicillin and Antiseptic, Oral Hygiene and Plaque, Bacterial Reproduction (Binary Fission), Asexual Reproduction, Positives and Negatives of Bacteria, Protista, Plant-like Protists, Animal-like Protists, Fungi-like Protists, Animalia, Characteristics of Animalia, Animal Symmetry, Phylums of Animalia (Extensive), Classes of Chordata, Mammals, Subclasses of Mammals, Characteristics of Mammals, Fungi, Positives and Negatives of Fungi, Divisions of Fungi (Extensive), Parts of a Mushroom, 3 Roles of Fungi, Fungi Reproduction, Mold Prevention, Plant Divisions, Kingdom Plantae. If you have any questions please feel free to contact me. Thanks again and best wishes. Sincerely, Ryan Murphy www.sciencepowerpoint@gmail.com
Children are at high risk of emotional disorders. These have become the most common reasons for their visits to the psychiatrist.
They include mood disorders, anxiety disorders, and trauma and stress-related disorders.
This slide explains each of these in details.
Enjoy
A detailed ppt which explains everything about the importance of human mental health
Including PTSD , Depression , ADHD , Obesity , Autism , Social media over usage , Inferior and superior complexity
Anxiety, defined as dread or apprehension, is not considered pathologic, is seen across the life span, and can be adaptive (e.g. the anxiety one might feel during an automobile crash).
Anxiety becomes disabling.
Interfering with social interactions, development.
Achievement of goals or quality of life.
Can lead to slow self esteem, social withdrawal.
Academic underachievement.
The average age of onset of anxiety disorder is 11 years.
This is the most common psychiatric disorders of childhood.
Occurs in 5-18% of all children and adolescents.
Prevalence rate is comparable to physical disorders such as asthma and diabetes.
One of the most common childhood anxiety disorder.
Prevalence- 3.5-5.4%
Girls ˃ boys
Common in prepubertal children. Average age of onset 7.5 yrs.
It is developmentally normal when it begins about 10 month of age and tapers off by 18 month.
By 3 years of age, most children can accept the temporary absence of their mother or primary caregiver.
SAD is characterised by unrealistic and persistent worries about separation from home or a major attachment figure.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
2. Major Depressive Disorder:
Diagnostic Criteria
5 of following symptoms, must include one
of first two, occurred almost every day for two
weeks
• Depressed mood
• Pleasure or interest/ Loss
• Appetite
• Sleep disturbance, too much or too little
• Agitation or retardation
• Fatigue
• Feelings of worthlessness or guilt
• Difficulty concentrating or deciding
• Recurrent thoughts of death
3. Depressive Symptoms Mnemonic:
”Space Drags
S leep disturbance D epressed mood
P leasure/interest (lack R etardation movement
of)
A ppetite disturbance
A gitation
G uilt, worthless,
C oncentration useless
E nergy (lack
of)/fatigue
4. Common presentation of
Depression in Children
• Frequent vague, non-specific physical complaints such
as headaches, muscle aches, stomachaches or
tiredness
• Frequent absences from school or poor performance in
school
• Talk of or efforts to run away from home
• Outbursts of shouting, complaining, unexplained
irritability, or crying
• Being bored
• Lack of interest in playing with friends
• Alcohol or substance abuse
5. Common presentation of
Depression in Children
• Social isolation, poor communication
• Fear of death
• Extreme sensitivity to rejection or failure
• Increased irritability, anger, or hostility
• Reckless behavior
• Difficulty with relationships
6. Assessment
• Consider the following when assessing a
child/young person
• with depression and record in the notes:
• potential co morbidities
• social, educational and family context for the
patient and family members
• quality of patient’s relationships with family
members, friends and peers.
7. Assessment
• Assess with the young person their social
network before treatment starts
• identify factors that:
– contributed to the development and
maintenance of depression
– impact in a positive or negative way on
treatment efficacy.
• Indicate ways to work in partnership with
their social and
• professional network
8. Assessment
• Always ask the child/young person and
their parents directly about the patient’s:
– alcohol and drug use
– experience of being bullied
– experience of being abused
– self-harm
– ideas about suicide
9. Assessment
• Give young people the opportunity to
discuss these issues initially in private.
• Pay special attention to:
– confidentiality
– young person’s consent (including
competence)
– parental consent
– child protection
10. Assessment
Consider parents’ mental health
● Consider the possibility of parental
depression and substance misuse (or
other mental health problems and
associated problems of living).
● Obtain a family history to check for uni-
polar or bipolar depression in parents and
grandparents in all children/young people
with suspected mood disorder.
11. General treatment
considerations
• Treat most children/young people on
an outpatient or community basis
12. Mild depression
• Antidepressant medication should not be
used for the initial treatment of children
and young people with mild depression
13. Moderate to severe
depression
first-line treatment:
• specific psychological therapy
– individual cognitive behavioral therapy [CBT],
– interpersonal therapy or
– shorter-term family therapy
• it is suggested that this should be of at least 3 months’
duration.
• Antidepressant medication should not be offered to a
child or young person with moderate to severe
depression except in combination with a concurrent
psychological therapy
14. • Fluoxetine should be prescribed as this is
the only antidepressant for which trials
show that benefits outweigh the risks.
• The starting dose should be 10 mg daily,
increased if necessary to 20 mg daily after
1 week.
• Consider lower doses for children of lower
body weight.
• ●).
15. • Consider the use of another
antidepressant (sertraline or citalopram
are the recommended second-line
treatments
• The starting dose should be half the daily
starting dose for adults,
• increased if necessary to the daily adult
dose gradually over 2 to 4 weeks.
Consider lower doses in children of lower
body weight
16. Length of treatment
• After remission (no symptoms and full
functioning for at least 8 weeks)
continue medication for at
least 6 months (after the 8-week
period).
17. Childhood Bipolar Disorder
• Forget a lot of what you know about adult
bipolar disorder symptoms
• symptoms of bipolar in children are quite
different. Mood swings in children can be
extremely fast, and various angry and
irritable behaviors are very common
18. Symptoms of mania
• euphoria (elevated mood)—silliness or elation that is inappropriate
and impairing
• grandiosity
• flight of ideas or racing thoughts
• more talkative than usual or pressure to keep talking
• irritability or hostility when demands are not met
• excessive distractibility
• decreased need for sleep without daytime fatigue
• excessive involvement in pleasurable but risky activities (daredevil
acts, hyper sexuality)
• poor judgment
• hallucinations and psychosis
For an episode to qualify as mania, there must be elevated mood plus
at least three other symptoms, or irritable mood plus at least four
other symptoms.
19. Symptoms of depression
• lack of joy and pleasure in life
• withdrawal from activities formerly enjoyed
• agitation and irritability
• pervasive sadness and/or crying spells
• sleeping too much or inability to sleep
• drop in grades or inability to concentrate
• thoughts of death and suicide
• fatigue or loss of energy
• feelings of worthlessness
• significant weight loss, weight gain or change in appetite
20. Very Common presentation of
Childhood Bipolar Disorder
• Separation anxiety
• Rages & explosive temper tantrums (lasting up to se
• Marked irritability
• Oppositional behavior
• Frequent mood swings
• Distractibility
• Hyperactivity
• Impulsivity
21. • Racing thoughts
• Restlessness/ fidgetiness
• Silliness, goofiness
• Sexualized behavior unusual for the child’s age
• Aggressive behavior
• Grandiosity
• Delusional beliefs and hallucinations
• Risk-taking behaviors
• Depressed mood
• Lethargy
• Low self-esteem
22. Challenges in Diagnosing
Children's Bipolar Disorder
• Distinguishing between normal behaviors and those that
may indicate bipolar disorder in a kid is more challenging
because:
• There are a significant number of other conditions whose
symptoms overlap with bipolar disorder, including
attention deficit hyperactivity disorder (ADHD),
oppositional defiant disorder (ODD), conduct disorder
(CD), obsessive compulsive disorder (OCD), anxiety,
depressive disorders and learning disabilities
23. Lines of treatment
A good treatment plan includes
• Medication,
• Close monitoring of symptoms,
• Education about the illness,
• Counseling or psychotherapy for the individual
and family,
• Stress reduction,
• Good nutrition,
• Regular sleep and exercise, and
• Participation in a network of support.
24. Psychotherapy
can help patients and their families
understand the illness, can teach the
importance of early relapse detection, and
ensure compliance with medication
• It include:
– Cognitive behavioral therapy
– interpersonal therapy
– multi-family support groups
25. Medication
• Atypical Antipsychotics Agents
• Risperdal, Zyprexa, Seroquel, Aripiprazole– These
newer agents are often used to treat bipolar disorders
in adults, children and adolescents and appear to be
effective mood stabilizers
• Mood Stabilizers
– Lithium
– anticonvulsant
• sodium valproic acid
• Carbamazepine
• Oxcarbazepine
• Lamotrigine