EEG is a non-invasive method to measure electrical activity in the brain. It can help in psychiatry by ruling out physical causes for psychiatric symptoms, aiding in differential diagnosis and treatment selection, and predicting prognosis. EEG findings can provide clues to underlying conditions in disorders like schizophrenia, mood disorders, OCD, panic attacks, dementia, delirium, and substance abuse. However, EEG findings in psychiatry are often nonspecific and EEG has limitations due to only recording cortical activity from the scalp. It currently has no definitive role in diagnosing Axis I or II psychiatric disorders.
Significance of Brain imaging in Psychiatry. Most of the major Psychiatric disorders are associated with statistically significant differences on various Neuroimaging measures, when comparing groups of patients and controls.
John Kane - Treatment-Resistant Schizophrenia: New Guidelines on Diagnosis an...wef
Presentation made at the live webinar hosted by the Schizophrenia Research Forum on the 21st of February, 2017 - http://www.schizophreniaforum.org/forums/treatment-resistant-schizophrenia-new-guidelines-diagnosis-and-terminology
Electroencephalography is the technique used to acquire electrical signals of brain through electrodes which are placed by certain montage. Different wave patterns can be observed which is useful in detecting any abnormal conditions or neurological brain disorders in human beings. There is broad future scope for medical research and creating EEG based equipments for real time applications.
Significance of Brain imaging in Psychiatry. Most of the major Psychiatric disorders are associated with statistically significant differences on various Neuroimaging measures, when comparing groups of patients and controls.
John Kane - Treatment-Resistant Schizophrenia: New Guidelines on Diagnosis an...wef
Presentation made at the live webinar hosted by the Schizophrenia Research Forum on the 21st of February, 2017 - http://www.schizophreniaforum.org/forums/treatment-resistant-schizophrenia-new-guidelines-diagnosis-and-terminology
Electroencephalography is the technique used to acquire electrical signals of brain through electrodes which are placed by certain montage. Different wave patterns can be observed which is useful in detecting any abnormal conditions or neurological brain disorders in human beings. There is broad future scope for medical research and creating EEG based equipments for real time applications.
This lecture is all about the recognition of an abnormal EEG, its characteristics, its appearance and all about how to differentiate the abnormal activity with normal EEG background.
Neuro electrophysiology is the study of the electrical properties of biological cells and tissues in the nervous system. The electroencephalogram (EEG) is the recording of electrical activity of brain.
Continuous spike and wave during slow wave sleep(CSWS)Faizan Abdullah
continuous spike and wave during slow wave sleep(CSWS) was first described by patry.
The syndrome is characterized by continuous spike and wave activity during non-REM sleep and is sometimes called as “Epilepsy with electrical status Epilepticus during slow sleep” (ESES ).
Onset ranges from 1-12 years peak age around 8 years.
2/3 of patients normal neurologically before onset. In time most patients have frequent seizures generalized tonic clonic , atypical absence and atonic also have a significant decline in IQ with deterioration in language, impaired memory , reduced attention span, and behavioral changes with aggression or psychosis epileptiform activity consists of generalized slow 1.5 to 2.5HZ spike wave as well as focal or multifocal spikes, which are sporadic in the waking state.
In sleep, spike-wave bursts become nearly continuous(CSWS pattern) , occupying more than 85% of the total NON-REM sleep time .
The csws pattern persists for one to several years. Similar to LKS, the EEG then tends to normalize and seizures remit spontaneously in most patients.
However recovery of neurological deficit and behavior is often incomplete and about half of the patients remain profoundly impaired.
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Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
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Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
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BÀI TẬP BỔ TRỢ TIẾNG ANH GLOBAL SUCCESS LỚP 3 - CẢ NĂM (CÓ FILE NGHE VÀ ĐÁP Á...
eeg basics in psychiatry
1. EEG IN PSYCHIATRY
- DR. DEEPIKA SINGH,
2ND YR RESIDENT,
DEPT. OF PSYCHIATRY,
GSMC & KEM HOSPITAL
2. WHAT IS EEG
Electroencephalography is non-invasive method for
investigation of electrical activity of brain.
Used to measure cortical neuronal activity through
detection of potential differences across scalp
3. HOW IT CAN
PSYCHIATRY:
HELP
IN
To rule out physical or
neurological causes before
making psychiatric diagnosis
May help in
diagnosis
and
selection
May help
prognosis
in
differential
treatment
predicting
4. OVERVIEW
How EEG is recorded
Normal EEG findings
Factors affecting EEG
Application of EEG
EEG in psychiatric disorders
5. How to record EEG
Electrode Placement
•10-20 percent system is used
•This system measures the distance
between readily identifiable
landmarks on the head and then puts
electrodes at 10 percent or 20 percent
of that distance in an anteriorposterior or transverse direction
•Even number for right hemisphere
and odd number for left hemisphere.
6. How to record EEG
Sensitivity:
Frequency
filter
setting
The amplification used in EEG recording
can be adjusted to visualize low-voltage
signals. Accepted standards across
laboratories for most recordings are
7microvolts for each millimeter of pen
deflection.
For clinical purpose frequency falls within
the range of 0.5 to 40.0 or 50.0 Hz. Setting
frequency filter appropriately helps to rule
out frequencies generated by non brain
sources.
7. SPECIAL ACTIVATIONS:
HYPERVENTILATION: Done with eyes closed and over breathing
through mouth. It is especially effective in eliciting Petit Mal
Seizure pattern.
PHOTIC STIMULATION: Done by placing an intense strobe light 12
inches in front of subject’s closed eyes and flashing at frequency
ranging from 1 to 50 Hz. More useful in detecting psychiatric
disorders
SLEEP: More useful in eliciting paroxysmal discharges
SLEEP DEPRIVATION: can be useful in eliciting paroxysmal
discharges
8. BRAIN WAVE
It is the difference in electric potential measured
between any two EEG electrodes which fluctuates
rapidly, many times a second leading to a “squiggly
line”.
10. NORMAL EEG TRACING
ALPHA RHYTHM
•Highly rhythmic with a frequency range from 8 to 13 Hz
•Constitute the dominant brain wave frequency of the normal eyes-closed
wake EEG.
•Alpha activity is also most prominent over the posterior cortex, particularly
the parietal, posterior temporal, and occipital cortex
•Occipital region being best suited to show this activity..
•Alpha activity is abolished by eye opening, and alpha activity also
disappears with drowsiness and sleep.
•Alpha activity can be highly responsive to cognitive activity, such as focused
attention or concentration. Example ,alpha can be blocked or attenuated by
engaging in visual imagery, numeric calculation etc.
11. NORMAL EEG TRACING
BETA RHYTHM
•Frequencies that are faster than the upper 13 Hz limit
•They are common in normal adult waking EEGs
•Particularly seen over frontal-central regions.
•The voltage of beta activity is also almost always lower
than that of activity in the other frequency bands
described previous
12. NORMAL EEG TRACING
THETA RHYTHM
•Waves with a frequency of 4.0 to 7.5 Hz
•It is a prominent feature of the drowsy and sleep tracing
•Although theta activity is limited in the waking EEG,
•A small amount of sporadic, arrhythmic, and isolated
theta activity can be seen in many normal waking EEGs,
particularly in frontal-temporal regions
•Excessive theta in wake, generalized or focal in nature,
suggests a focal pathological process
13. NORMAL EEG TRACING
NORMALRHYTHM
DELTA EEG TRACING
•Delta activity (equal to or less than 3.5 Hz) is not present in the
normal waking EEG
•Is a prominent feature of deeper stages of sleep.
•The presence of significant generalized or focal delta in the wake
EEG is strongly indicative of a Pathophysiological process
GAMMA RHYTHM
Evidence has been provided that high frequency oscillations
within the gamma band (>30Hz) reflect mechanisms of
cortical integration
14. FACTORS AFFECTING EEG
Changes with Age
•Preponderance of irregular medium- to highvoltage delta activity in the tracing of the infant
•EEG activity gradually increases in frequency and
becomes more rhythmic with increasing age
•Rhythmic activity in the upper theta–lower alpha
range (7~to 8 Hz) can be seen in posterior areas by
early childhood
•By mid-adolescence EEG has the appearance of
an adult tracing.
15. FACTORS AFFECTING EEG
Changes with sleep
•The rhythmic posterior alpha activity of the
waking state subsides during drowsiness and is
replaced by irregular low-voltage theta activity.
•As drowsiness deepens, slower frequencies
emerge, and sporadic vertex sharp waves may
appear at central electrode sites
•The progression into sleep is marked by the
appearance of 14-hz sleep spindles (also called
sigma waves)
•Which, in turn get replaced by high-voltage
delta waves as deep sleep stages are reached.
16.
17. FACTORS AFFECTING EEG
Artifacts
•Artifacts are electric potentials of
nonbrain origin that are in the frequency
and voltage range of EEG signals and that
are detected by scalp electrodes.
•Common artifacts include eye blinks,
vertical or lateral eye movements, muscle
potentials from jaw clenching, perspiration
artifacts (galvanic skin response), and head
movement.
•Automatic artifact rejection programs
exist for some computerized research
applications, but they have not strongly
entered the clinical arena.
18. FACTORS AFFECTING EEG
Changes with Medications
•Benzodiazepines always generate significant
amount of diffuse beta activity.
•The highest proportion of abnormal EEGs occurred
with Clozapine followed by lithium
•Lithium is capable of causing abnormal generalized
slowing, paroxysmal activity, or both, including a 10
percent incidence of toxic delirium
•The highest incidence of EEG abnormalities was
associated with clozapine >olanzapine > risperidone,
fluphenazine >haloperidol. There was no EEG
abnormalities seen with quetiapine.
19. EEG IN PSYCHIATRIC DISORDERS
Currently there is no accepted indication of EEG in diagnosing either axisI or II disorders
20. :
EEG IN
SCHIZOPHRENIA
•EEG abnormalities have overall frequency of 20-60%.
•May predict conversion of subjects at risk into
psychosis
•Their presence indicate worse outcome.
•It helps to identify those with comorbid epileptic
condition.
•Epileptiform variants are found in affective disorder
with psychotic feature and schizoaffective disorder but
not in schizophrenia.
EEG in Catatonia
EEG abnormalities in schizophrenia :
•Dysrhythmia
•Spike and spike –and- wave
•Generalized slowing
EEG can help to find out specific
etiology of catatonia as catatonia
may be caused by several organic
disorders
21. EEG IN MOOD DISORDERS:
•Abnormal EEG found in 20-40% of patients
•In bipolar patients increase in beta activity and
decrease in alpha activity noted
•Acute mania has increased posterior slow rhythms
•An asymmetric alpha activity in left frontal region
has been reported in depression
•Unipolar and bipolar depression have sleeping EEG
recording abnormality i.e., short REM latency,
increased REM density and reduction in stage 3 and
4 of sleep.
•Frequent increase sharp spikes,6/sec spike in
patients with suicidal ideation
22. EEG in OCD:
EEG in OCD
EEG abnormalities present in varying frequency]
Widespread increase in slow waves reported
EEG in Panic
disorders
•25-30% of panic attack patients have
EEG abnormalities
•Helps in differentiating panic attack from
epilepsy
•focal paroxysms of sharp wave activity
coinciding with spontaneous onset of
panic attack is noted
23. EEG in
DEMENTIA
•Increased slow activity and
decreased mean frequency are
correlated
with
cognitive
impairment and measures clinical
severity of Alzheimer's dementia
•The amount of theta activity shows
the best correlation with cognitive
deterioration
•Increased delta appears to be
correlate of severe advanced
dementia, occurring subsequent to
increased theta
24. EEG in
DELIRIUM
•Hallmark of delirium usually is the slowing of
the background EEG rhythm
•This is positively correlated with the degree
of severity of the condition
•Exception is in delirium tremens (DT), which
usually shows a normal EEG record with fast
rhythms.
•Delirium accompanying the neuroleptic
malignant syndrome shows only a mild diffuse
slow wave.
•Delirium can be differentiated from
dementia, and the significant factors are an
increased theta activity
25. EEG in Alcohol and
Substance Abuse
• Acute Alcoholic intoxication shows slowing in the EEG, seen
as decreased alpha frequency and abundance & increased
amount of theta, and even some generalized delta rhythm
• These slow waves have a relationship with the degree of
intoxication. The extent of the disturbance of consciousness
is related to the amount of slow activity
• Reports have appeared of an increased beta (relative
power) in alcohol dependence
• Increased alpha power, especially in anterior regions, has
been reported in withdrawal, as well as after acute exposure
to cannabis
26. PROBLEMS WITH EEG IN
PSYCHIATRY
•Nonspecificity of findings
•Problem with placing electrodes in
psychiatric patients
•Limitations of scalp EEG i.e.,Only onethird of brain can be covered,EEG
activity of sub-cortical area can’t be
recorded
•Currently there is no accepted
indication of EEG in diagnosing either
axis-I or II disorders
Editor's Notes
Nasopharyngeal and sphenoid electrodes can be used to improve readings from frontal, temporal regions.Sphenoidal electrode gives more positive results than regular electrodes but it is an invasive procedure