Livestock Protective Fence (LPF) for enhanced milk production and mastitis control in intensive zero-grazing dairy farms in Kenya-Dr. Rajinder Kumar Saini
This document summarizes a study on the use of livestock protective fences (LPFs) to control flies and improve dairy production in Kenya. The key findings were:
1) LPFs reduced fly populations by over 50%, mastitis infections by 46-88%, and malaria cases in humans by 36-61%.
2) Milk production increased by 27-45% with LPFs, resulting in $233-480 more income annually per household.
3) Treatment costs for mastitis and disease fell by $78-114 per household over 2 years with LPFs.
4) Farmers were willing to pay $0.9-2.35 annually for LPFs and wanted
Successful management of delayed case of mastitis in cowsuren vet
In this we tried & eliminated pathogens with low antibiotics. The withdrawl period of milk is decreased. Treatment is of low cost. Easily applicable in field condition....
Successful management of delayed case of mastitis in cowsuren vet
In this we tried & eliminated pathogens with low antibiotics. The withdrawl period of milk is decreased. Treatment is of low cost. Easily applicable in field condition....
Want it more automatic, accurate and faster? For milking robots (also called AMS, VMS, robotic milking) or for laboratories?
Try Ekomilk-AMP which includes Ekomilk Horizon, AMP and AMPI Sample Feeder:
http://animalmonitoring.com/
With Wifi, Bluetooth, barcode reader and RFID support, USB, ...
Youtube intro video:
https://www.youtube.com/watch?v=zE3_XrkW7rI
--------------------------------------------------
Ekomilk Scan+ for milk producers and veterinarians provides accurate and quick somatic cell count (SCC) per quarter, per cow and for the dairy herd at only around 0.04$/test. With somatic cell measurement and monitoring (thanks to the included software), udder inflammation “mastitis” of milk cows can be detected at an early stage and udder health can be improved. In turn, milk production and quality (also important for dairy processing like cheese and yoghurt) can be improved at the dairy farm. Ekomilk Scan is a cost-effective and easy-to-use digital cell meter (counter) which also helps reducing laboratory costs. It is important to avoid a too high cell level in the milk tank.
Current status and future challenges in mastitis researchHenk Hogeveen
A couple of years ago, we gathered with 9 individual mastitis experts, to freely discuss issues around mastitis.
One of the results was an overview paper on the current status and future challenges of mastitis research. It was presented at the 50th anniversary Annual Meeting of the NMC (www.nmconline.org). These are the slides of this presentation, given by Joe Hogan and myself.
Mastitis disease effects on cheese making via influence on time of milk clotting by rennet, softness of clotting, more leak of whey and developed of acidity.
Implementing and Evaluating a Selective Dry Cow Therapy ProgramDAIReXNET
Pamela Ruegg joins us to discuss selective dry cow therapy. Learn about implementing and evaluating a program, as well as how to decide whether selective therapy might be a good fit for your operation. View the full presentation at https://www.youtube.com/watch?v=VKRAqHQZIng
Want it more automatic, accurate and faster? For milking robots (also called AMS, VMS, robotic milking) or for laboratories?
Try Ekomilk-AMP which includes Ekomilk Horizon, AMP and AMPI Sample Feeder:
http://animalmonitoring.com/
With Wifi, Bluetooth, barcode reader and RFID support, USB, ...
Youtube intro video:
https://www.youtube.com/watch?v=zE3_XrkW7rI
--------------------------------------------------
Ekomilk Scan+ for milk producers and veterinarians provides accurate and quick somatic cell count (SCC) per quarter, per cow and for the dairy herd at only around 0.04$/test. With somatic cell measurement and monitoring (thanks to the included software), udder inflammation “mastitis” of milk cows can be detected at an early stage and udder health can be improved. In turn, milk production and quality (also important for dairy processing like cheese and yoghurt) can be improved at the dairy farm. Ekomilk Scan is a cost-effective and easy-to-use digital cell meter (counter) which also helps reducing laboratory costs. It is important to avoid a too high cell level in the milk tank.
Current status and future challenges in mastitis researchHenk Hogeveen
A couple of years ago, we gathered with 9 individual mastitis experts, to freely discuss issues around mastitis.
One of the results was an overview paper on the current status and future challenges of mastitis research. It was presented at the 50th anniversary Annual Meeting of the NMC (www.nmconline.org). These are the slides of this presentation, given by Joe Hogan and myself.
Mastitis disease effects on cheese making via influence on time of milk clotting by rennet, softness of clotting, more leak of whey and developed of acidity.
Implementing and Evaluating a Selective Dry Cow Therapy ProgramDAIReXNET
Pamela Ruegg joins us to discuss selective dry cow therapy. Learn about implementing and evaluating a program, as well as how to decide whether selective therapy might be a good fit for your operation. View the full presentation at https://www.youtube.com/watch?v=VKRAqHQZIng
Presentations from a session held during the 2013 National Mastitis Council Annual Meeting provide a brief overview of milk quality from various dairy industries across the globe. Includes demographics, milk quality parameters, and other unique practices from Colombia, Italy, Spain, Uruguay, Chile, Germany, New Zealand, United States, Canada, and Great Britain.
rumen, microbes of the rumen, bacteria of the rumen, process in ruminant animals, gut of ruminant animals, bacterial concentrations in ruminant animals, bacterial fluctuations in ruminant animals
Kenyan perceptions of aflatoxins: An analysis of raw milk consumptionILRI
Presentation by Maria Walke, Nadhem Mtimet, Derek Baker, Johanna Lindahl, Monika Hartmann and Delia Grace at the 14th congress of the European Association of Agricultural Economists (EAAE), Ljubljana, Slovenia, 26-29 August 2014.
Clinical Pathology Laboratory Report by Kula Jilo 2016kula jilo
Clinical pathology is a subspecialty of pathology that deals with the use of laboratory methods (clinical chemistry, microbiology, hematology and emerging subspecialties such as molecular diagnostics) for the diagnosis and treatment of disease. Hematology studies the blood and blood-forming tissues to evaluate presence of disease and assist in therapeutic interventions as clinically indicated. Clinical chemistry (also known as chemical pathology and clinical biochemistry) is the area of clinical pathology that is generally concerned with analysis of bodily fluids. Some of the objectives of this manual are to identify the most important hematological and functional pathological tests of vet importance, to diagnose different animal diseases by confirming the pathological causes that constraint livestock production and to have knowledge more about clinical pathology. Part one discusses about hematology which includes equipment’s and reagents, blood collection sites and procedures, preparation method for working solution, staining methods (staining procedures), hemoglobin determination, hematocrit determination (PCV), total RBC count, total WBC count, differential leukocyte count, determination of ESR, coagulation time determination, bleeding time, calculating red blood cell indices and blood group and Rh factor determination. Part two deals with function tests which includes determination of Aspartate Amino Trasferase (AST) and Glutamic OxalacetateTransminase (GOT), determination of Alkaline Phosphtase (ALP), determination of creatinine, total protein determination, urea determination, total and direct bilirubin determination, enzymatic kinetic colorimeter test, liver function test, kidney function test, rumen function test and pancreatic function test. In general, the outline of this laboratory manual deals with the basic hematological procedures and clinical chemistry analysis.
Similar to Livestock Protective Fence (LPF) for enhanced milk production and mastitis control in intensive zero-grazing dairy farms in Kenya-Dr. Rajinder Kumar Saini
The future of sustainable livestock systems in low- and middle-income countriesILRI
Presented by Shirley Tarawali at the Expert dialogue: The future of sustainable agriculture. Let’s think about… livestock, German Federal Ministry for Economic Cooperation and Development (BMZ), 28 June 2022
No food security without food safety: Lessons from low- and middle-income cou...ILRI
Presentation by Delia Grace, Florence Mutua, Johanna Lindahl, Kristina Roesel and Silvia Alonso at the Australian Veterinary Association Annual Conference, Perth, Australia, 5–10 May 2019.
How can Animal Biotechnology contribute to Agenda 2063, ST&I Strategy for Afr...ILRI
Presented by Christian K. Tiambo, Jimmy Smith, Okeyo Mwai and Steve Kemp at the Animal Biotechnology: The Next Frontier Stakeholders Sensitization and Awareness Workshop on Animal Biotechnology Applications and Regulatory Perspectives, Naivasha, Kenya, 22-24 March 2021
Measuring and mitigating the risk of mycotoxins in maize and dairy products f...ILRI
Presentation by Johanna Lindahl, Alexia Pretari, Delia Grace, Hannu Korhonen and Vivian Hoffmann at a FoodAfrica seminar on global food security, Helsinki, Finland, 12 April 2016.
Measuring and mitigating the risk of mycotoxins in maize and dairy products for poor consumers in Kenya, Johanna Lindahl (ILRI) and Alexia Pretari (IFPRI)
Animal Disease Control Programs in India.pptBhoj Raj Singh
India is a hyperendemic country for many animal diseases and zoonotic diseases. Every year billions of rupees are spent on disease control, surveillance, monitoring, and vaccination against vaccine-preventable diseases. However, due to the failure of most animal disease control programs for one or other reasons India directly losses about 20 and 25 thousand crores annually due to endemicity of FMD & brucellosis, respectively. The presentation describes the pros and cons of different ongoing disease control programs going on in India.
Importance of livestock and the technological and policy challenges facing th...ILRI
Presented by Michael Blϋmmel, Phil Toye, Okeyo Mwai, Ian Wright, Tom Randolph and Steve Staal at the Global feed and food congress, Sun City, South Africa, 10-12 April 2013
Bacteriophages a viable alternative to antibiotic use in poultry farmingILRI
Poster prepared by Nicholas Svitek, ILRI Angela Makumi, Nicoline de Haan and Sylvain Moineau for the Virtual Livestock CRP Planning Meeting, 8-17 June 2020
Similar to Livestock Protective Fence (LPF) for enhanced milk production and mastitis control in intensive zero-grazing dairy farms in Kenya-Dr. Rajinder Kumar Saini (20)
Basics of animal nutrition
Feeding the rumen microbes
We need:
Certain limiting amino acids (Lys, Met)
In a certain ratio (Lys 3 : 1 Met)
And normal feedstuffs don’t supply this:
Not enough
Not the right ratio
So we need to supplement them
We need RUP
Weak, inequitable and inefficient systems
Poor are dependent on systems for their livelihoods that do not work well
TechnoServe strives to make Market Systems work for the poor
Improved production & more effective markets
Animal health Product development & adoption Partnership organisation
A not-for-profit Public-Private Partnership – registered charity
Sponsored by the UK Department for International Development (DFID) and The Bill & Melinda Gates Foundation (BMGF) and with projects funded by BMGF, DFID and EC.
Pro-poor focus: working with key partners to make a sustainable difference in access to animal health products for poor livestock keepers
Inadequate livestock farmers’ knowledge and skills is one of the limiting factors to the development of the industry. Knowledge and skills are important for quick adoption of appropriate technology, which has been developed and disseminated to livestock farmers.
Vision, Mission, Aim
VISION
To be the leading voice for the grain industry in Africa.
MISSION
To advocate for enabling environment and promote structured grain trade for optimum stakeholder benefits.
AIM
To develop, promote, and influence structured grain trading system in the Eastern Africa region with defined rules and regulations.
Improve the policy and trading environment in the regional grain trade
Strengthen market linkages and
Reduce constraints along the grain value chain.- Quality Grain
Animal Welfare is gaining recognition as an important element of commercial livestock operations worldwide.
This has wide-ranging implications for an industry with complex historical and cultural roots.
It is being addressed not only by governmental agencies and academic institutions, but by a growing number of professionals at different locations in the agricultural supply chain.
A number of regional and global initiatives have emerged to provide guidance on acceptable practices to actors ranging from individuals caring for animals on farms to large scale commercial enterprises providing animal-based products from different livestock systems.
To have at least two (and up to six) typical farms for each region.
The first farm is an average sized farm with an average management performance. The second farm is larger than the first one but also having an average management performance, to show economies of scale.
They represent major milk production systems, farms, milk produced in region
Consultancy specialising in the food and drinks industries.
Core of 50 staff based in Bath, UK, as well as a large network of on-the-ground analysts throughout the world who have specific specialist expertise.
All staff are specialists in food and drink, particularly in the beverages and dairy industry.
Commercial and technical expertise in the food and drinks industry, alongside our events.
To attain a fully integrated internationally competitive regional economic community
Mission
To achieve increased co-operation and integration in all fields of development
Complement National Agenda and address Trans- boundary Issues
Consultative Process
Apply Programme Approach – COMESA
Involves Regional Stakeholders including, MSs
Signed in Kinshasa DRC, 14th November 2014
Value Chain Devt – Significant
Milk Quality Tracking and Tracing System as a Basis for Quality Based Milk Payment System
In Kenya, raw milk safety has been disputed over a decade but no documented data exists.
Greatest milk quality challenge for the CBE’s are proper ways to maintain cold collection.
The regulatory institutions are constrained financially hence raw milk quality standards are reluctantly applied and enforced.
This creates a vacuum for farmers to switch between buyers of raw milk specially due to quality issues.
Realblends Tailor Made Stabilizers for the Food Industry
CONVENIENCE TREND
People increasingly have to “manage” competing demands on their time. Convenience impacts all aspects of people’s lives forcing them to constantly seek out more efficient and effective products that help improve busy lifestyles and free-up and maximize leisure time
Convenience is a major force behind much product innovation resulting in strong growth in ready to eat products as well as products which simplify routine tasks.
What Product/s do you want to produce?
•What will your capacity be?
•Milk Quality/Juice with preservatives?
•How Flexible do you want to be?
•Will you contract pack?
•Product Shelf Life/cold chain
SUSTAINABLE COOPERATIVE DEVELOPMENT IN AFRICA
Cooperatives play an important role in economic development of many countries across the continent.
In Kenya, cooperatives are controlling about 43% of GDP and 31% of national savings and deposits. They have 70% of the coffee market, 76% dairy, 90% pyrethrum, and 95% of cotton.
In Benin, FECECAM (Faitiere des caisses deparge et de credit agricole mutuel), a savings and credit cooperative federation, provided USD 16 million in rural loans in 2002.
In Côte d'Ivoire cooperatives invested USD 26 million for setting up schools, building rural roads and establishing maternal clinics.
In Kenya, over 300,000 people are directly employed by co-operatives
Globally, cooperatives provide over 100 million jobs around the world, 20% more than multinational enterprises.
Milk Makes People Great
About Acre Africa
Agricultural Risks
Why Dairy Insurance
Challenges
Way Forward
We are a micro-insurance product designer linking stakeholders in the agricultural sector to insurance products through localized solutions that reduce climate-associated risk.
We operate as an insurance intermediary – an organization that is not an insurance company, but rather working with local insurers and other stakeholders in the agricultural insurance value chain.
We are a registered insurance surveyor in Kenya, an insurance agent in Rwanda, with registration on-going in Tanzania.
We have 24 staff members from diverse professional fields such as Insurance, Agriculture and Veterinary Sciences, Actuarial Science, Marketing and Finance
Calf Coccidiosis
General about coccidia- Structure- Life cycle- Environmental factors for survival
Eimeria in cattle- Prevalence- Clinical coccidiosis- Sub-clinical coccidiosis
Surveillance and control
What is Coccidiosis?
Enteric disease caused by the protozoan parasites Eimeria spp
Daily routine of a dairy cow
voluminous products, which lay firm on the floor
…thick, wear resistant mats
…very durable but animal-friendly soft
…produced in a patented process
…single mats, easy to install
…the right mat for each purpose
More from African Dairy Conference and Exhibition (20)
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Livestock Protective Fence (LPF) for enhanced milk production and mastitis control in intensive zero-grazing dairy farms in Kenya-Dr. Rajinder Kumar Saini
1. Animal Health Packages
Livestock Protective Fence (LPF) for enhanced milk
production and mastitis control in intensive zero-grazing
dairy farms in Kenya
International Fund for Agricultural Development
Food and Agricultural Organization of UN
R.K. Saini, B. Bauer, M. Mattoni, R.C. Mattoli and P. Muasa
2. Zero-grazing Units and flies
Productivity of smallholder dairy cows is constrained
by multiple of animal diseases e.g. mastitis,
helminthosis, tick borne diseases and in some
cases tsetse transmitted trypanosomiasis
• Cows in zero grazing units attract flies
which bite the animals and cause agitation,
spread diseases and contribute to
unsanitary conditions.
• Flies reduce productivity of dairy cows and
cause weight loss
• Wounds from stable and biting flies may
become infected
• In some areas even tsetse flies are
attracted to zero-grazing units
3. Waste pits and flies
• Waste pits are breeding grounds of
biting (including mosquitoes)
and non-biting flies
• Waste management is also a problem
4. Biting flies in Zero Grazing Units
Stomoxys on a cow A Cow responding to biting
flies while feeding
Stable and other biting flies mechanically transfer disease agents
to the animal hosts causing, eye infections and mastitis
5. Development of site specific Animal Health Packages
As part of development of site specific animal
health packages, a Rapid Rural Appraisal of
zero-grazing units in Kenya was undertaken
to:
• Determine the diseases affecting their
cattle and control practices being adopted
• Assess the status of the zero grazing
units
• Identify appropriate project sites for
interventions
• Activities within the Smallholder Dairy
Commercialization Programme (SDCP) which
covers 9 districts (GoK project funded by IFAD)
ICIPE team setting a NGU trap
CDC trap
10. LPFs as part of Animal Health Package
• In Kisii, 105 zero- grazing units and waste pits
were protected with LPF as part of
development of site specific animal health
packages
• In Bungoma – 30 semi-zero grazing units were
protected
Bungoma
Kisii
11. HOW LPF WORKS
Flies are attracted to
odours of animals in
pens
LPF (Insecticide treated
screen) is attached to
pen perimeter
Flies don’t see open
mash; land on it and are
killed by insecticide in
fibers of the screen
Flies travel at low levels (<1.5m) and will land on the LPF, pick up the
insecticide (deltamethrin) and die within 24 hours (10-20 sec exposure is
enough)
LPF supplied by Vestergaard Frandsen
15. Milk Off take in Kisii
Before LPFs
Mosocho produced the least milk
while Keumbu produced the most
amongst the Dairy Commercialization
Areas (DCAs) under SDCP in Kisii
After introduction of LPFs
milk production in Mosocho has
surpassed all the DCAs where LPFs
were not introduced
29. Social and Economic Impacts of Livestock Protective
Fence (LPF) Technology for Protecting Dairy Cows in
Zero-grazing Enterprises in Kenya
30. LPNF mastitis incidence in Kisii & Bungoma
Dairy cows of 76% respondents
had previous mastitis infections
No. of biting flies positively
correlated with mastitis
infections (r=0.406 at 0.01
significance level)
Mean mastitis
infections per
cow before LPNF
use
Mean mastitis
infections per
cow after LPNF
use
% change
Kisii
Zero grazing LPNF 3.94 0.47 88.07%
Waste Pit LPNF 3.71 1.81 51.21%
Control (No LPNF) 3.5 3.5 -
Bungoma 2.67 0.25 9 1 %
Mean number of mastitis incidence in Kisii and Bungoma before and after LPNF
use
31. Constraint of flies to animal production
• 80 % farmers cite biting flies as a serious
constraint causing animal irritability,
agitation (97%); interference with stall
feeding, wastage of feeds (scattering and
trampling of feed – 100%)
• Common method of controlling flies –
swatting
• Use of human capital - during milking 2
persons deployed – one for swatting and
one for milking
• farmers estimate a loss of 1.5 liters per
milking event before LPFs – loss of 27%
milk in Kisii and 33% in Bungoma
32. LPNFs and Milk Production
Mean milk yields (litres/cow/day) in Kisii and Bungoma
Mean milk yield (litres/cow/day) in two years
Before LPNF After LPNF Percentage
LPNFs positively influence milk off-take by:
• reducing the number of biting and non-biting flies
• reducing disease morbidity
• improving dairy animal feeding behavior
• improving milking experience both for the animal and the farmer.
change
Kisii Zero grazing LPNF 5.99 8.18 37%
Kisii Waste Pit LPNF 5.25 6.98 33%
Overall Kisii LPNF 5.62 7.58 35%
Kisii No LPNF (Control) 5.17 5.17
Bungoma zero grazing
LPNF
4.50 7.65 70%
Bungoma No LPNF
(Control)
4.69 4.69
33. Impact on LPNFs on human diseases
Mean malaria infections per household per year
Mean malaria infections per household per year
Before LPNF After LPNF Percentage
change
Kisii Zero grazing LPNF 4.44 1.76 60%
Kisii Waste Pit LPNF 5.08 2.40 53%
Kisii No LPNF (Control) 4.70 -
Bungoma zero grazing LPNF 4.92 1.92 61%
Bungoma No LPNF (Control
5.14 -
group)
• LPNFs have positive effect on human health.
• LPNFs around zero grazing units were more
effective in controlling malaria-causing mosquitoes
than nets around waste pits
• This could be attributed to attraction of mosquitoes
to humans and cattle which are in closer proximity
of dwelling units next to zero grazing units than
waste pits.
34. Gender and development impacts of LPNFs
LPNFs and gross economic benefits from milk sales
Table 7: Gender disaggregated milk yields and gross economic
benefits
County LPNF
Household
type
Mean milk
production
before
LNPF
(Litres/Day)
Mean milk
production
after LNPF
(Litres/Day)
Yield
gain
(Litres
/day)
*Average
additional
economic
gain/HH/day
(Ksh)
Gross
annual
benefit/
Hh/Year
(Ksh.)
Gross
annual
benefit/
Hh/Year
(US$)
Kisii Male 6.63 9.22 2.59 129.63 27,222 324.07
Female 4.61 6.48 1.87 93.48 19,630 233.70
Bungoma Male 4.4 7.5 3.1 186.00 39,060 465.00
Female 4.6 7.8 3.2 192.00 40,320 480.00
Market price for milk in Kisii Ksh.50/litre and Bungoma Ksh.60/litre
35. LPNF and cost savings in the reduction of mastitis infections
Table 10: Gender disaggregated savings from reduced mastitis infections
per household over a 2 year period
County LPNF
Household
type
Mean
mastitis
infections
per Hh 2
years
before
LNPF
Mean
mastitis
infections
per Hh 2
years after
LNPF
Variance *Average
cost saving
per Hh
(Ksh)
Average cost
saving per Hh
(US $)
Kisii Male 3.85 0.65 3.19 9,577 114
Female 3.81 1.63 2.19 6,563 78
Bungoma Male 2.63 0.25 2.38 7,125 85
Female 2.72 0.25 2.47 7,395 88
* Average cost of treating uncomplicated mastitis is Ksh. 3000 (US$35.71)/animal for a single incident
Picture by M. Mattoni
36. Combined economic benefits two years after LPNFs
Table 13: Combined economic benefits realised in two years after LPNF
Benefit Average cost
savings per Hh
after LPNF (US $)
Additional average
gross income per
Hh after LPNF
(US $)
Kisii Bungoma Kisii Bungoma
Additional milk sales after LPNF 556 944
Cost savings in treatment of complicated malaria per
1187.5 1031.74
household
Cost savings in treatment of mastitis infections 96.07 86.43
Cost savings in treatment of helminthosis infections 28.19 39.3
Cost savings in reduced livestock mortality 670 611
Average combined cost savings per household 1,981.76 1,768.47
Average direct earnings per household 556 944
Total average benefit per household (cost savings +
2537.76 2712.47
direct earnings)
37. Farmers perceptions of the LPF technology
• 100% of farmers in Bungoma and Kisii rate LPF to be very effective against
controlling biting and non biting flies.
• All farmers want to continue using the LPF technology.
• All control group farmers are willing to adopt the technology
• No major negative effects were reported except for skin irritation upon contact
with LPNF (20% of farmers in Kisii)
How much are farmers ready to pay for LPNFs?
• Bungoma: Ksh. up to 200 (US$2.35) /m/yr (average Ksh.120/ m/yr -US$1.41)
• Kisii: Ksh. up to 100 (US$1.8)/m/yr (average Ksh. 75/m/yr -US$ 0.9)
http://www.youtube.com/watch?v=eD6Ve_SjW08 on FAO website
38. Netting in a Dairy Farm in Nebraska, USA
Introduced by
USDA in
June 2013
39. International Fund for Agricultural Development
Acknowledgements
Centre International de Recherche-
Developpement Sur l'Elevage en Zone
Subhumide
Technical Staff:
John Andoke
Peter Muasa
David Mbuvi
Tiberius Marete
John Ngiela
Philip L. Kolei Caroline
Muya
Private Sector- LPF supplied by Vestergaard Frandsen
Consultants:
B. Bauer - Free University of Berlin, Institute for Parasitology and Tropical Veterinary
Medicine, Berlin, Germany
M. Mattoni - Università degli Studi di Torino Facoltà di Medicina Veterinaria Dipartimento
di Produzioni Animali, Epidemiologia ed Ecologia Via Leonardo Da Vinci,
Italy