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PCV2 vaccination strategies Jean-Bernard HERIN, Merial  France
Agenda ,[object Object],[object Object],[object Object],[object Object]
PCV2 characteristics and image ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],« What we currently know »
PCVD: 3 risk factors ,[object Object],[object Object],[object Object],[object Object],Courtesy: Dr K. Mc Cullough Immunostimulation « What we currently know »
Evolution of the disease  Sporadic Acute Chronic In France Very rare ≈  80% Quite all 1995-2002 Mortality  PCVD < 1 % Up to 35 % 5 to 15 % Control measures None Management Medication Genetic Before 1995 Since 2002 Vaccination: sow/piglets Management Medication Genetic « What we currently know »
PMWS in 1995-2000 « What we currently know »
PCVD in 2005-2010 « What we currently know »
In pigs, has the disease changed?  Yes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],« What we currently know »
Mortality rate in Brittany Zootechnical measures, genetic changes and vaccination  allowed to control PCVD Data from GTE –GTTT : source IFIP- EDE Bretagne 2010 Sow vaccination Piglet/Sow vaccination Madec’s rules Genetic «How to control this changing disease»
ADWG (8 to 115 kg) Growth performance improved with PCV2 vaccination Sow vaccination Piglet/Sow vaccination Madec’s rules Genetic Data from GTE –GTTT : source IFIP- EDE Bretagne 2010 «How to control this changing disease»
PCV2 vaccination challenges ,[object Object],[object Object],[object Object],«How to control this changing disease»
PCV2 Vaccination options ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],«Optimizing the vaccination strategy» Possible synergy ?
« Assault program » : piglets vaccination ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],«Optimizing the vaccination strategy»
« Complete program »: sow and piglets ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],«Optimizing the vaccination strategy»
« Basic program » : sows ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],«Optimizing the vaccination strategy»
Dynamics of the programs Choice of the program COMPLETE program : Sow + piglets No vaccination BASIC program: Sow + gilts ASSAULT program : piglets Clinical PMWS Subclinical PMWS Demonstrative? (Show) vaccination Coinfections Bad colostrum intake The best security Better coinfections management  To reduce vaccination cost Optimal colotrum intake «Optimizing the vaccination strategy»
Slaughter age (115 kg) /PCV2 vaccination program 18 herds, 63 500 piglets  «Field results of Circovac programs »
Mortality rate / PCV2 vaccination program *** ** ***p<0,001  **p<0,05 18 herds, 63 500 piglets  «Field results of Circovac programs »
Baromètre 2010 de la  Evolution of the  PCV2 vaccination
Evolution of the vaccination rate PCV2 Vaccination farmer phone survey : 301 FTF herds  PCV2– July – Aug 2010 33 35 21 15 19 21 16 14 2 2 0 5 10 15 20 25 30 35 40 2010 (301 herds) 2009 (313 herds) 2007 (304 herds) % of herds Vaccination rate (%) Sow vaccination only (%) Piglet vaccination only (%) Sow and/or piglet vaccination (%)
(*) technical level evaluated by the number of weaned piglets/sow/year: bottom group less than 23 piglets, Average group between 23 and 27,  top group more than 27.  PCV2 Vaccination farmer phone survey : 301 FTF herds  PCV2– July – Aug 2010 Evolution of the vaccination rate 33,2 27 34,8 61,5 31 36,1 44 26,2 32 0 10 20 30 40 50 60 70 Top group (*) Average group (*) Bottom group (*) Other areas Brittany 300 sows and + 200-299 sows 100-199 sows Farrow-to-finish farms Fréquence en % des éleveurs de chaque classe
Expected benefits of the different programs Basic (Sow) Assault (Piglets) Complete (Sow+Piglets) Gilts acclimatization ++ 0 ++(+) Sow reproduction ++ 0 ++(+) Post weaning ++ + ++(+) Fattening +(+) ++ ++(+) Vaccination cost 100 250-300 350-400 ROI 9 4 (3 or more !)
Possible herd segmentation* in 2015  * Source : C Roguet IFIP – JRP 09 French example CIRCOVAC Programs Brittany  (Density,PRRSV and  SIV +++) Other regions (Low density,PRRS and FLU -)   300 sows FTF farms (1-2 FTE) ,[object Object],[object Object],Basic Large multisite herds  (600 to 2000 sows, FTF or FTW) (2-7 FTE, excellent performances needed, security +++)   Complete (sow + piglets) Basic  Collectives farrowing units(< 860 sows) (2-3 FTE, excellent performances needed, security +++)   Assault (piglets)  Or Complete if reproductive problems  Basic if possible
Conclusion ,[object Object],[object Object],[object Object],[object Object]
CIRCOVAC benefits… ,[object Object]

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03 vaccinationstrategieslast herin

  • 1. PCV2 vaccination strategies Jean-Bernard HERIN, Merial France
  • 2.
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  • 5. Evolution of the disease Sporadic Acute Chronic In France Very rare ≈ 80% Quite all 1995-2002 Mortality PCVD < 1 % Up to 35 % 5 to 15 % Control measures None Management Medication Genetic Before 1995 Since 2002 Vaccination: sow/piglets Management Medication Genetic « What we currently know »
  • 6. PMWS in 1995-2000 « What we currently know »
  • 7. PCVD in 2005-2010 « What we currently know »
  • 8.
  • 9. Mortality rate in Brittany Zootechnical measures, genetic changes and vaccination allowed to control PCVD Data from GTE –GTTT : source IFIP- EDE Bretagne 2010 Sow vaccination Piglet/Sow vaccination Madec’s rules Genetic «How to control this changing disease»
  • 10. ADWG (8 to 115 kg) Growth performance improved with PCV2 vaccination Sow vaccination Piglet/Sow vaccination Madec’s rules Genetic Data from GTE –GTTT : source IFIP- EDE Bretagne 2010 «How to control this changing disease»
  • 11.
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  • 15.
  • 16. Dynamics of the programs Choice of the program COMPLETE program : Sow + piglets No vaccination BASIC program: Sow + gilts ASSAULT program : piglets Clinical PMWS Subclinical PMWS Demonstrative? (Show) vaccination Coinfections Bad colostrum intake The best security Better coinfections management To reduce vaccination cost Optimal colotrum intake «Optimizing the vaccination strategy»
  • 17. Slaughter age (115 kg) /PCV2 vaccination program 18 herds, 63 500 piglets «Field results of Circovac programs »
  • 18. Mortality rate / PCV2 vaccination program *** ** ***p<0,001 **p<0,05 18 herds, 63 500 piglets «Field results of Circovac programs »
  • 19. Baromètre 2010 de la Evolution of the PCV2 vaccination
  • 20. Evolution of the vaccination rate PCV2 Vaccination farmer phone survey : 301 FTF herds PCV2– July – Aug 2010 33 35 21 15 19 21 16 14 2 2 0 5 10 15 20 25 30 35 40 2010 (301 herds) 2009 (313 herds) 2007 (304 herds) % of herds Vaccination rate (%) Sow vaccination only (%) Piglet vaccination only (%) Sow and/or piglet vaccination (%)
  • 21. (*) technical level evaluated by the number of weaned piglets/sow/year: bottom group less than 23 piglets, Average group between 23 and 27, top group more than 27. PCV2 Vaccination farmer phone survey : 301 FTF herds PCV2– July – Aug 2010 Evolution of the vaccination rate 33,2 27 34,8 61,5 31 36,1 44 26,2 32 0 10 20 30 40 50 60 70 Top group (*) Average group (*) Bottom group (*) Other areas Brittany 300 sows and + 200-299 sows 100-199 sows Farrow-to-finish farms Fréquence en % des éleveurs de chaque classe
  • 22. Expected benefits of the different programs Basic (Sow) Assault (Piglets) Complete (Sow+Piglets) Gilts acclimatization ++ 0 ++(+) Sow reproduction ++ 0 ++(+) Post weaning ++ + ++(+) Fattening +(+) ++ ++(+) Vaccination cost 100 250-300 350-400 ROI 9 4 (3 or more !)
  • 23.
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  • 25.

Editor's Notes

  1. Je ne comprends pas bien le haut de la diapo avec l’axe evolution (axe temps? Pourquoi « Jamais ») Taux de mortalité: les barres d’histogramme représente-t-elles le taux de mortalité? Dans ce cas, il faudrait qu’elles soient proportionnelles
  2. Il faudrait marquer le moment d’apparition de la MAP et des vaccins PCV2
  3. Il faudrait marquer le moment d’apparition de la MAP et des vaccins PCV2
  4. Je ne comprends pas la recommandation pour els mater coll: vaccination truies et ajout du porcelet si pb de repro?