This document summarizes several lipid storage diseases: Tay Sachs disease results from hexosaminidase A deficiency leading to ganglioside accumulation and is classified based on neurological symptom onset. Gaucher disease stems from glucocerebrosidase deficiency causing glucosylceramide storage in reticuloendothelial cells. Niemann Pick disease types A and B involve sphingomyelin accumulation in the liver, spleen, and bone marrow due to different enzymes. Several other diseases are mentioned that involve deficiencies in enzymes responsible for degrading specific lipids.