SlideShare a Scribd company logo
present by
Jinal Chauhan
3RD YEAR 5th SEM
BMCO
Limbus
The limbus is:
- A transition zone of the epithelia and
connective tissues of the cornea, and the
conjunctiva and sclera combined.
 Cornea to Conjunctiva/Sclera Transition
 (Hogan et al., 1971)
Cornea Conjunctiva
5 layer epithelium 10 to 15 layer
epithelium
Bowman's layer stroma and
Tenon's capsule
stroma sclera proper
 Epithelial radial ‘pegs’ produce the Palisades of
Vogt, which are seen more in the inferior and
superior quadrant and may be pigmented in darker
races. The Palisades arise from the stroma of the
conjunctiva.
 Legend for slide 64:
 a = termination of Bowman’s
Layer
 b = epithelial rete pegs
 Co = conjunctival cross-section
 d = superficial marginal arterial
plexus
 e = terminal vessels
 f = recurrent vessels
 g = peripheral lymphatic system
 h = superficial radial lymphatic
group
 i = deep radial lymphatic
 ACA = anterior ciliary artery
 EA = episcleral arteries
 EVP = episcleral venus plexus
The limbal epithelium is anatomically different
from
that of the bulbar conjunctiva because:
It does not have goblet cells.
The limbal epithelium is different from the
corneal
epithelium because:
It does contain melanocytes.
cornea limbal Balbur
conjunctiva
Goblet cells - - yes
melanocytes - yes yes
Underlying
blood
vessels
- yes yes
LIMBAL EPITHELIUM
DIMENSIONS OF THE
LIMBAL REGION
 depth : 1.0 mm
 Width : 1.5 mm (horizontally)
2.0 mm (vertically
LIMBAL FUNCTION
 • Nourishment
 • Aqueous humor drainage
Limbal Vasculature
 Begins with arteries from the
superficial marginal
 arterial plexus which originates
from the anterior
 ciliary arteries. There are two
types of limbal
 vessels:
 Terminal arteries which form
the peripheral
 cornea arcades.
 Recurrent arteries which form
the peripheral
 arcades which pass through the
Palisades of
 Vogt to supply the perilimbal
conjunctiva.
Limbal Innervation
 (Hogan et al., 1971)
 Limbal nerves arise from the intrascleral and
 conjunctival nerves. These originate from the
 long ciliary nerves (A).
 Innervation extends into the trabecular
 meshwork (B) and the cornea (C).
 Note that:
 The deep cornea (D) has few nerves.
 The cornea adjacent to Descemet’s membrane
 (E) has no nerves
Thank you …..

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Limbus

  • 1. present by Jinal Chauhan 3RD YEAR 5th SEM BMCO
  • 2.
  • 3. Limbus The limbus is: - A transition zone of the epithelia and connective tissues of the cornea, and the conjunctiva and sclera combined.
  • 4.
  • 5.  Cornea to Conjunctiva/Sclera Transition  (Hogan et al., 1971) Cornea Conjunctiva 5 layer epithelium 10 to 15 layer epithelium Bowman's layer stroma and Tenon's capsule stroma sclera proper  Epithelial radial ‘pegs’ produce the Palisades of Vogt, which are seen more in the inferior and superior quadrant and may be pigmented in darker races. The Palisades arise from the stroma of the conjunctiva.
  • 6.  Legend for slide 64:  a = termination of Bowman’s Layer  b = epithelial rete pegs  Co = conjunctival cross-section  d = superficial marginal arterial plexus  e = terminal vessels  f = recurrent vessels  g = peripheral lymphatic system  h = superficial radial lymphatic group  i = deep radial lymphatic  ACA = anterior ciliary artery  EA = episcleral arteries  EVP = episcleral venus plexus
  • 7. The limbal epithelium is anatomically different from that of the bulbar conjunctiva because: It does not have goblet cells. The limbal epithelium is different from the corneal epithelium because: It does contain melanocytes. cornea limbal Balbur conjunctiva Goblet cells - - yes melanocytes - yes yes Underlying blood vessels - yes yes LIMBAL EPITHELIUM
  • 8. DIMENSIONS OF THE LIMBAL REGION  depth : 1.0 mm  Width : 1.5 mm (horizontally) 2.0 mm (vertically
  • 9. LIMBAL FUNCTION  • Nourishment  • Aqueous humor drainage
  • 10. Limbal Vasculature  Begins with arteries from the superficial marginal  arterial plexus which originates from the anterior  ciliary arteries. There are two types of limbal  vessels:  Terminal arteries which form the peripheral  cornea arcades.  Recurrent arteries which form the peripheral  arcades which pass through the Palisades of  Vogt to supply the perilimbal conjunctiva.
  • 11.
  • 12. Limbal Innervation  (Hogan et al., 1971)  Limbal nerves arise from the intrascleral and  conjunctival nerves. These originate from the  long ciliary nerves (A).  Innervation extends into the trabecular  meshwork (B) and the cornea (C).  Note that:  The deep cornea (D) has few nerves.  The cornea adjacent to Descemet’s membrane  (E) has no nerves

Editor's Notes

  1. Limbal Function - Provides limited nourishment to the peripheral cornea via the limbal vasculature. - Site of the aqueous humor drainage system including Schlemm’s canal. This system is important for the maintenance of the intraocular pressure