The document provides information about the Laryngeal Mask Airway (LMA) and I-gel devices for airway management:
[1] It discusses the indications, contraindications, equipment, and step-by-step process for inserting the LMA. Proper sizing, lubrication, and positioning are emphasized.
[2] Placement must be verified by ensuring equal breath sounds on both sides and absence of sounds over the epigastrium. Problems like improper deflation or folding can occur.
[3] The I-gel is introduced as a single-use, cuffless airway device with an integral gastric channel and epiglottis blocking ridge to facilitate insertion.
mapleson circuits used in anesthesia practice, are in their way out but it is as important to know the mechanism with which the gases flow to and fro through them.
A breathing system is a device that conducts gases such as oxygen and anesthetic agents to the patient and conducts waste gases such as CO2 away.
Breathing systems are classified as
Open,
Semi-open,
Semi-closed
Closed.
Semi-closed systems are further divided into
Rebreathing Systems With CO2 Absorption,
Rebreathing Systems Without CO2 Absorption
Non-rebreathing Systems.
More simply, systems can be classified in two groups:
systems with CO2 washout (includes open and semi-open systems)
systems with CO2 absorption (includes closed and semi-closed systems).
mapleson circuits used in anesthesia practice, are in their way out but it is as important to know the mechanism with which the gases flow to and fro through them.
A breathing system is a device that conducts gases such as oxygen and anesthetic agents to the patient and conducts waste gases such as CO2 away.
Breathing systems are classified as
Open,
Semi-open,
Semi-closed
Closed.
Semi-closed systems are further divided into
Rebreathing Systems With CO2 Absorption,
Rebreathing Systems Without CO2 Absorption
Non-rebreathing Systems.
More simply, systems can be classified in two groups:
systems with CO2 washout (includes open and semi-open systems)
systems with CO2 absorption (includes closed and semi-closed systems).
The insertion of a cannula or a tube into a hollow organ such as intestines or trachea, to maintain an opening or passageway is known as intubation.
The insertion of a long breathing tube or artificial airway (endotracheal tube - ETT) into the trachea (windpipe) via the mouth is called endotracheal intubation
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
Email / Skype : kefaya1771@gmail.com
Threema: PXHY5PDH
New BATCH Ku !!! MUCH IN DEMAND FAST SALE EVERY BATCH HAPPY GOOD EFFECT BIG BATCH !
Contact me on Threema or skype to start big business!!
Hot-sale products:
NEW HOT EUTYLONE WHITE CRYSTAL!!
5cl-adba precursor (semi finished )
5cl-adba raw materials
ADBB precursor (semi finished )
ADBB raw materials
APVP powder
5fadb/4f-adb
Jwh018 / Jwh210
Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stockrebeccabio
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stock
Telegram: bmksupplier
signal: +85264872720
threema: TUD4A6YC
You can contact me on Telegram or Threema
Communicate promptly and reply
Free of customs clearance, Double Clearance 100% pass delivery to USA, Canada, Spain, Germany, Netherland, Poland, Italy, Sweden, UK, Czech Republic, Australia, Mexico, Russia, Ukraine, Kazakhstan.Door to door service
Hot Selling Organic intermediates
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
3. During The Presentation
PLEASE:
• Put cell-phones on silent/vibrate mode.
• Take emergency calls outside.
• Maintain silence.
HOSPITALS
4. Laryngeal Mask Airway (LMA) & I-gel
– An introduction
Dr Rajesh T Eapen
Specialist – Anesthesia
ATLAS HOSPITAL
Ruwi
5. For my Nursing Colleagues:
Speak tenderly to them.
Let there be kindness in your face,
In your eyes, in your smile,
In the warmth of your greeting.
Always have a cheerful smile.
Don’t only give your care,
But give your heart as well.
Mother Teresa
5
8. Objectives:
• Identify the indications, contraindications and side
effects of LMA use.
• Identify the equipment necessary for the placement
of an LMA.
• Discuss the steps necessary to prepare for LMA
placement.
• Discuss the methods of LMA placement.
• Identify and discuss problems associated with LMA
placement.
• Introduce I-gel
• How to insert the I-gel
10. Introduction
• The LMA was invented by Dr.
Archie Brain at the London
Hospital, Whitechapel in 1981
• The LMA consists of two parts:
– The mask
– The tube
• The LMA has proven to be very
effective in the management of
airway crisis
11. Introduction continued
• The LMA design:
– Provides an “oval seal
around the laryngeal
inlet” once the LMA is
inserted and the cuff
inflated.
– Once inserted, it lies at
the crossroads of the
digestive and respiratory
tracts.
12. ROLE OF LMA IN ASA’S DIFFICULT
AIRWAY ALGORITHM
LMA has role in the management of difficult airway as:
A) ventilatory device
B) as a conduit to aid tracheal intubation
The laryngeal mask airway, as a ventilatory device and/or
intubating conduit, can be placed into the ASA difficult
airway algorithm in five places
1) As an intubation conduit in the awake intubation limb
2) As an intubation conduit in the non-emergency pathway
in anaesthetized patient.
3) As an airway device in the non-emergency pathway in
the non-emergency pathway in anaesthetized patient.
13. 4) As an airway device in the emergency
pathway ( CVCI of the algorithm)
5) As a conduit to endotracheal intubation in
the emergency pathway (CVCI)
14. The laryngeal mask airway fits into the ASA algorithm on the management of the
difficult airway in five places, as an airway (ventilatory device) or a conduit for a
fiberscope. 14
Laryngeal Mask Airway and the ASA Difficult Airway Algorithm
15. Indications for the
use of the LMA
• Situations involving a difficult mask (BVM) fit.
• May be used as a back-up device where
endotracheal intubation is not successful.
• May be used as a “second-last-ditch” airway
where a surgical airway is the only remaining
option.
16. Equipment for
LMA Insertion
• Appropriate size LMA
• Syringe with appropriate volume for LMA cuff
inflation
• Water soluble lubricant
• Ventilation equipment
• Stethoscope
• Tape or other device(s) to secure LMA
17. Preparation of the
LMA for Insertion
• Step 1: Size selection
• Step 2: Examination of the LMA
• Step 3: Check deflation and inflation of
the cuff
• Step 4: Lubrication of the LMA
• Step 5: Position the Airway
18. Step 1: Size Selection
• Verify that the size of the LMA
is correct for the patient
• Recommended Size guidelines:
– Size 1: under 5 kg
– Size 1.5: 5 to 10 kg
– Size 2: 10 to 20 kg
– Size 2.5: 20 to 30 kg
– Size 3: 30 kg to small adult
– Size 4: adult
– Size 5: Large adult/poor seal with size 4
19. Step 2: Examination
of the LMA
• Visually inspect the LMA cuff for tears or
other abnormalities
• Inspect the tube to ensure that it is free of
blockage or loose particles
• Deflate the cuff to ensure that it will maintain
a vacuum
• Inflate the cuff to ensure that it does not leak
20. Step 3: Deflation and
Inflation of the LMA
• Slowly deflate the cuff to form a smooth
flat wedge shape which will pass easily
around the back of the tongue and behind
the epiglottis.
• During inflation the maximum air in cuff
should not exceed:
– Size 1: 4 ml
– Size 1.5: 7 ml
– Size 2: 10 ml
– Size 2.5: 14 ml
– Size 3: 20 ml
– Size 4: 30 ml
– Size 5: 40 ml
21. Step 4: Lubrication
of the LMA
• Use a water soluble lubricant to lubricate the LMA
• Only lubricate the LMA just prior to insertion
• Lubricate the back of the mask thoroughly
Important Notice:
• Avoid excessive amounts of lubricant
– on the anterior surface of the cuff or
– in the bowl of the mask.
• Inhalation of the lubricant may result
in coughing or obstruction.
22. Step 5: Positioning
of the Airway
• Extend the head and
flex the neck
• Avoid LMA fold over:
– Assistant pulls the lower
jaw downwards.
– Visualize the posterior
oral airway.
– Ensure that the LMA is
not folding over in the
oral cavity as it is
inserted.
24. LMA Placement
Carries prominent
position in ASA algorithm
Balloon partially inflated
Directed posteriorly and
upwards towards the
palate
Jaw thrust and sniffing
position may help
placement
25. LMA Insertion Step 1
• Grasp the LMA by
the tube, holding it
like a pen as near as
possible to the mask
end.
• Place the tip of the
LMA against the
inner surface of the
patient’s upper teeth
26. LMA Insertion Step 2
• Under direct vision:
– Press the mask tip
upwards against the hard
palate to flatten it out.
– Using the index finger,
keep pressing upwards
as you advance the mask
into the pharynx to
ensure the tip remains
flattened and avoids the
tongue.
27. LMA Insertion Step 3
• Keep the neck flexed
and head extended:
– Press the mask into the
posterior pharyngeal
wall using the index
finger.
28. LMA Insertion Step 4
• Continue pushing
with your index
finger.
– Guide the mask
downward into
position.
29.
30.
31. LMA Insertion Step 5
• Grasp the tube firmly
with the other hand
– then withdraw your
index finger from the
pharynx.
– Press gently downward
with your other hand to
ensure the mask is fully
inserted.
32. LMA Insertion Step 6
• Inflate the mask with the
recommended volume of
air.
• Do not over-inflate the LMA.
• Do not touch the LMA tube
while it is being inflated
unless the position is
obviously unstable.
– Normally the mask should be
allowed to rise up slightly out
of the hypopharynx as it is
inflated to find its correct
position.
33. Verify Placement of the
LMA
• Connect the LMA to a Bag-Valve Mask device
or low pressure ventilator
• Ventilate the patient while confirming equal
breath sounds over both lungs in all fields
and the absence of ventilatory sounds over
the epigastrium
34. LMA Placement
Verify placement by ventilating
– Check for good chest rise, EtCO2, and
adequate tidal volumes
– Check for leak – if significant leak at around
10cm H2O problematic
– May try size larger or smaller
– May try to inflate/deflate cuff to obtain better
seal
– If difficulty passing may try inserting upside
down and then flipping around
35. Securing the LMA
• Insert a bite-block or roll of gauze to prevent
occlusion of the tube should the patient bite
down.
• Now the LMA can be secured utilizing the
same techniques as those employed in the
securing of an endotracheal tube.
37. Problems with
LMA Insertion
• Failure to press the
deflated mask up
against the hard palate
or inadequate
lubrication or deflation
can cause the mask tip
to fold back on itself.
38. Problems with
LMA Insertion
• Once the mask tip has
started to fold over, this
may progress, pushing
the epiglottis into its
down-folded position
causing mechanical
obstruction
39. Problems with
LMA Insertion
• If the mask tip is deflated
forward it can push down the
epiglottis causing obstruction
• If the mask is inadequately
deflated it may either
– push down the epiglottis
– penetrate the glottis.
40. he LMA Classic™ was first introduced in the U.K.
in 1988 and in the U.S. in 1992 as an alternative
to the face mask.
Curved tube ( shaft) connected to an elliptical
spoon- shaped mask ( cup) at a 30˚ angle.
Two flexible vertical bars to prevent the tube
from being obstructed by epiglottis.
An inflatable cuff
An inflation tube
Self sealing pilot balloon
41.
42. Clinical benefits:
More secure than a face mask
Allows single-handed ventilation
Rapid, blind insertion (no laryngoscopy)
43.
44. Wire- reinforced, reinforced LMA
It can be bent to any angle without kinking.
It is less likely to be displaced during head
rotation.
USE- Head n neck surgeries, surgeries of
upper torso.
INSERTION – difficult to insert. A stylet is to
be inserted into the tube to stiffen it.
45. PROBLEM – Small diameter of the tube limits
the size of endoscope or tracheal tube that
can be passed through it.
Smaller tube causes increased resistence.
It is unsuitable for MRI.
46.
47. It has a short, curved stainless steel shaft
with 15 mm connector.
Metal handle is securely bonded to the shaft
to facilitate one handed insertion, position
adjustment.
A v-shaped guiding ramp is built to direct the
tube.
Recommended in both difficult airway and
Resuscitation algorithm
Allows intubation with minimal head and
neck manipulation
48.
49.
50. INSERTION- in neutral position.
one hand movement in sagittal plane.
is held by handle, parallel to patient’s
chest.
it is inserted with a rotational movement
along the hard palate and post pharyngeal
wall.
USES- TRACHEAL INTUBATION- by the tube
recommended by the manufacturer.
Blind intubation
Blind nasal intubation
Fiberscopic guided intubation
Light guided intubation
51. PROBLEMS WITH INTUBATION
– any pharyngeal pathology
- LMA FASTRACh tracheal tube is expensive.
smallest size 3 for 30 kg weight
intubation can not be done in less than this
weight.
52.
53. It is similar to LMA Fastrach in construction.
It has 2 built-in channels, one to convey light
from and the other to convey the image to
the viewer.
The fiberoptic system can be autoclaved.
The monitor is attached to the LMA-Ctrach
via a magnetic latch connector.
Sizes- 3,4, 5.
USE- It is lubricated and inserted without
viewer attached, airway secured, ventilated
then viewer attached.
54.
55. Introduced by Dr. Archie Brain in 2000.
Has two separate tubes that effectively
separate the GI and respiratory tracts.
Three dimensional inflation of cuff
Holds a better cuff seal pressure.
Drainage Tube- helps to eliminate the
aperture bars and to facilitate gastric tube
insertion.
The PLMA airway tube is flexible and wire
reinforced. It has built-in bite block at the
proximal end.
56.
57.
58.
59.
60.
61. It is a sterile, disposable product made up of
PVC.
It has a special built-in curve which
correspondes the natural human anatomy.
NO aperture bars.
It is an alternative of face mask for achieving
and maintaining the airway.
The cuff is flexible and tip is reinforced.
These facilitate insertion and also prevent
the tip from folding.
62. LMA generally demonstrates
Ability to be placed without direct
visualization
Better cardiovascular stability both
during insertion and removal
Minimal IOP and ICP changes
Provide little protection against
aspiration
C/I in full stomach patients
63. Summary
• Recent studies suggest that the LMA is an
airway device that paramedics “adapt to
rapidly”. Paramedics have proven themselves
very successful in the placement of the LMA.
• Though endotracheal intubation remains the
definitive technique for securing an airway in
the pre-hospital setting, it is believed that the
LMA may help in a small percentage of
patients who prove to be difficult to intubate
endo-tracheally.
64.
65.
66. Single use, cuff-less
Integral gastric channel
Epiglottis blocking ridge
Moulding feature