The framework of bones and cartilage which gives shape and support to the body an animal is called skeleton. Skeletal structure is composed of hard material which is made up of calcium called bones. The human skeleton is made up of 206 bones. In human beings, the skeleton is present in side the body, so it is called endoskeleton.
The framework of bones and cartilage which gives shape and support to the body an animal is called skeleton. Skeletal structure is composed of hard material which is made up of calcium called bones. The human skeleton is made up of 206 bones. In human beings, the skeleton is present in side the body, so it is called endoskeleton.
Throughout history, the symbol of the skull and crossbones has served as a representation of mortality, likely owing to the fact that following death and decay, bones are the sole remnants. Many individuals perceive bones as inert, desiccated, and fragile. While these attributes accurately portray the bones of a preserved skeleton, the bones within a living human being are profoundly alive. Living bones exhibit strength and flexibility, serving as the primary components of the skeletal system.
A joint is an articulation between two bones in the body and are broadly classified by the tissue which connects the bones. The three main types of joints are: synovial, cartilaginous and fibrous.
Throughout history, the symbol of the skull and crossbones has served as a representation of mortality, likely owing to the fact that following death and decay, bones are the sole remnants. Many individuals perceive bones as inert, desiccated, and fragile. While these attributes accurately portray the bones of a preserved skeleton, the bones within a living human being are profoundly alive. Living bones exhibit strength and flexibility, serving as the primary components of the skeletal system.
A joint is an articulation between two bones in the body and are broadly classified by the tissue which connects the bones. The three main types of joints are: synovial, cartilaginous and fibrous.
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NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
2. Types of Joints
There are 3 main types of joint found in the body.
1. Fixed or Immoveable Joints
The bones at an immoveable joint cannot move -
they overlap or interlock, and are held together by
a tough fibre, e.g. the skull.
2. Slightly Moveable Joints
The bones at a slightly moveable joint can only move
a little - they are held together by strong straps
called ligaments and are joined by protective pads
known as cartilage, e.g. the ribs.
3. Freely Moveable Joints
At a freely moveable joint the bones move freely.
They are also known as synovial joints, and
are the largest group of joints found in the body,
e.g. the hips, shoulders and knees.
3. CLASSIFICATION OF JOINT BY
STRUCTURE
Fibrous: Have no cavity and are held together by
fibrous connective tissue – e.g. the sutures of the skull
bones
Cartilaginous: Also have no cavity. There is cartilage
between the bones of the joint. May be found between
the vertebrae of the spine
Synovial: Has a fluid filled cavity surrounded by an
articular capsule. The articulating surfaces are covered in
hyaline cartilage – e.g. the hinge joint of the knee
4. CLASSIFICATION OF JOINT BY
MOVEMENT
Fibrous or synarthrosis: Does not allow any movement,
which makes more sense when you know where in the
body they occur, as they supply protection – e.g. for the
brain
Cartilaginous or amphiarthrosis: Allows only limited
movement
Synovial or diarthrosis: Is freely moving, as much as
the shape of the articulating surface will allow.
5.
6. JOINT / MOVEMENT TYPES
Joint type Shape of joint Movement range Body place : articulating
bones
Ball + socket ball shaped bone fits
into cup shaped socket
3 axes F/E AB/AD R C hip : femur, acetabulum of pelvis
shoulder : scapula, humerus
Hinge convex and concave
surfaces fitting together
1 axis F/E knee : femur, patella, tibia
elbow : humerus, radius, ulna
Pivot ring shaped surrounding 1 axis R spine / atlas : odontoid process of axis
a cone (turns head from side to side)
elbow : proximal ends of radius and ulna
Condyloid modified ball and socket
giving circumduction
2 axes F/E AB/AD C knuckle joints of fingers : metacarpals,
phalanges
wrist : radius, carpals
Saddle shaped like a saddle
giving circumduction
2 axes F/E AB/AD C joint at base of thumb : carpal,
metacarpal
Gliding two flat gliding surfaces a little in all directions centre of chest : clavicle, sternum
wrist : carpals
ankle : tarsals
spine : articulating surfaces of vertebrae
7. In the picture below the ball and socket joint at the hip allows the player to
get height and then the ball and socket joint at the shoulder allows him to
SLAM DUNK!!
12. RELATIONSHIP of MUSCULAR SYSTEM to
SKELETAL SYSTEM
NAMES OF MAJOR MUSCLE GROUPS
Example : biceps
ORIGIN (static end) : coracoid process / glenoid fossa tubercle of humerus
INSERTION (moving end) : tuberosity of radius
FASCIA
connectivetissue
example: epimysium
LIGAMENTS
attach boneto bone
example: kneejoint
cruciateligaments
TENDONS
attach muscleto bone
viaPERIOSTEUM
example: achillestendon
PERIOSTEAL
LAYERS
attach tendons to bone
MUSCULAR
ATTACHMENTS
APONEUROSIS
aflattened ribbon
shaped tendon
13. Cartilage, Tendons, Ligaments: What’s the
difference?
Cartilage Tendons Ligaments
Tough
Attaches bone to
muscle
Attaches bone to
bone
Flexible Sturdy Elastic
At end of bone Non elastic Stabilise
Cushions
Size changes
depending on
muscle
Made of many
fibres
Anchor Strong
14. Types of Synovial Joints
Freely moveable (synovial) joints can
be divided into six groups depending upon
how they move.
KEY
Ball & Socket Joint
Hinge Joint
Pivot Joint
Gliding Joint
Saddle Joint
Condyloid Joint
15. Joints
Synovial Joints
• The articular capsule is a fibrous tissue encasing
the joint, forming a capsule
• The synovial membrane acts as a lining to the
joint capsule and secretes synovial fluid
• The articular/hyaline cartilage covers the ends of
the articulating bones
• Synovial fluid fills the joint capsule nourishes and
lubricates the articular cartilage
16. Joints
Synovial Joints
• Ligaments are white fibrous connective tissues
joining bone to bone, making the joint more stable
• Bursa is found where tendons are in contact with
bone. It forms a fluid filed sac between the tendon
and bone and helps reduce friction
• Articular discs of cartilage act as shock absorbers
• Pads of fat act as buffers to protect the bones form
wear and tear
21. • ball-and-socket
• head of humerus
• glenoid cavity of
scapula
• loose joint capsule
• bursae
• ligaments prevent
displacement
• very wide range of
movement
8-15
Shoulder Joint
22. • hinge joint
• trochlea of humerus
• trochlear notch of
ulna
• gliding joint
• capitulum of
humerus
• head of radius
• flexion and extension
• many reinforcing
ligaments
• stable joint
8-17
Elbow Joint
23. • ball-and-socket joint
• head of femur
• acetabulum
• heavy joint capsule
• many reinforcing
ligaments
• less freedom of
movement than
shoulder joint
8-19
Hip Joint
24. • largest joint
• most complex
•medial and lateral
condyles of distal end of
femur
•medial and lateral
condyles of proximal end
of tibia
•femur articulates
anteriorly with patella
• modified hinge joint
•flexion/extension/little
rotation 8-21
Knee Joint
•strengthened by many
ligaments and tendons
•menisci separate femur
and tibia
• bursae