As part of a class presentation, we attempted to make this to briefly explain what Torticollis meas, the Types of presentation of Torticollis, and Management strategies for a Physiotherapist for Congenital Torticollis especially.
I hope this helps. :)
The pictures and information had been taken from internet, complied to make a brief presentation for the purpose of class presentation.
I do not own any content.
As part of a class presentation, we attempted to make this to briefly explain what Torticollis meas, the Types of presentation of Torticollis, and Management strategies for a Physiotherapist for Congenital Torticollis especially.
I hope this helps. :)
The pictures and information had been taken from internet, complied to make a brief presentation for the purpose of class presentation.
I do not own any content.
Waddling gait- definition|role of muscle|gait analysis|kinematic and spatiote...jasna ok
This powerpoint is about WADDLING GAIT,muscle that cause waddling gait , its causes, reasons for why this gait is called duck gait and pregnancy gait, gait analysis , and its physical therapy treatment
Waddling gait- definition|role of muscle|gait analysis|kinematic and spatiote...jasna ok
This powerpoint is about WADDLING GAIT,muscle that cause waddling gait , its causes, reasons for why this gait is called duck gait and pregnancy gait, gait analysis , and its physical therapy treatment
Herniated Disk in the Lower Back
Sometimes called a slipped disc, a herniated disk most often occurs in your lower back. It is one of the most common causes of low back pain, as well as leg pain (sciatica).
Herniated Disc symptoms: sharp, burning or stabbing pain in back, may also run down leg; onset is often sudden.
Condition and Causes
Between 60% and 80% of people will experience low back pain at some point in their lives. A high percentage of people will have low back and leg pain caused by a herniated disk.
Although a herniated disk can sometimes be very painful, most people feel much better with just a few weeks or months of nonsurgical treatment.
What is structure of lumber disc? What is disc bulge/prolapse/herniation? What is difference between disc bulge, disc prolapse, disc herniation or disc extrusion? What is criteria to diagnose lumber disc prolapse? How lumber disc herniation is treated medically or surgically? How lumber disc herniation is treated by conservative method? How lumber disc herniation is treated through physical therapy? What is physiotherapy after various disc surgeries? What is radiological method to diagnose disc prolapse?
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
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NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
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Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
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INTERVERTEBRAL DISC ANATOMY AND PIVD OF LUMBAR SPINE AND ITS MANAGEMENT
1. INTRODUCTION TO
INTERVERTEBRAL DISC ANATOMY,
PIVD (LUMBAR) AND ITS
MANAGEMENT
Presented by:
Dr. Ben Tungoe
PG, M.S(Orthopedics)
Central Institute of Orthopedics
VMMC & Safdarjung Hospital,
New Delhi
2.
3. ANATOMY OF INTERVERTEBRAL DISC
• fibro cartilaginous structure.
• contributes 25% of the height of spinal column.
• function of shock absorption, transmitting compressive loads between vertebral bodies.
• Composed of the central nucleus pulposus(NP), the peripheral annulus fibrosus(AF) and
the end plates(EP).
• The end plate is a bilayer of cartilage that separate the IVD from the vertebral
body(VB) and serves as growth plate for the VB.
4. NUCLEUS PULPOSUS:
– Highly hydrated structure, approx.
88% water
– Hydrophilic matrix: composed of
proteoglycans(PG) interspersed
within an irregular mesh of type-2
collagen and elastin fibers.
– The proteoglycans have a large
number of anionic
glycosaminoglycans(GAG) side
chains i.e chondroitin sulfate and
keratan sulfate which allows the
nucleus to imbibe water.
– Low collagen and high PG ratio.
– Characterised by compressibility.
5. ANNULUS FIBROSUS
-composed of concentric rings/lamellae of highly
organised Type-1 collagen fibres which are
interwoven.
-high collagen and low PG ratio
-the fibres are oriented 60 degree to the vertical
axis of spine and parallel within each lamella and
perpendicular between adjacent lamallae.
-lamallae are thicker anteriorly and laterally and
thinner posteriorly
-AF functions to contain the NP and maintain its
pressurization under compressive loads.
-characterized by extensibility and tensile strength
6. BLOOD AND NERVE SUPPLY
• Blood Supply
– the disk is avascular with capillaries terminating at
the end plates
– nutrition reaches nucleus pulposus
through diffusion through pores in the endplates
• annulus is not porous enough to allow
diffusion
• Innervation
– the dorsal root ganglion gives rise to the
sinuvertebral nerve which innervates
the superficial fibers of annulus
• no nerve fibers extend beyond the superficial
fibers
– neuropeptides thought to participate in sensory
transmission include
• substance P
• calcitonin
• VIP
• CPON
7. Distribution of load in the
inter-vertebral disc.
(A) In the normal, healthy disc, the
nucleus distributes the load equally
throughout the annulus.
(B) As the disc undergoes
degeneration, the nucleus loses some
of its cushioning ability and transmits
the load unequally to the annulus.
(C) In the severely degenerated disc,
the nucleus has lost all of its ability to
cushion the load, which can lead to
disc herniation.
8. Disc Biomechanics
• Disc
– viscoelastic characteristics
• demonstrates creep which allows for deformity over time
• demonstrates hysteresis which allows for energy absorption with repetitive axial
compression
– this property decreases with time
• Stresses
– annulus fibrosus
• highest tensile stresses
– nucleus pulposus
• highest compressive stress
– Intra-discal pressure is position dependent
• pressure is lowest when lying supine
• pressure is intermediate when standing
• pressure is highest when sitting and flexed forward with weights in the hands
• when carrying weight, the closer the object is to the body the lower the pressure
• Stability
– following subtotal discectomy, extension is most stable loading mode
9. Pathoanatomy
• Disc Herniation
– herniated disks are associated with a spontaneous increase in the production of
• osteoprotegrin (OPG)
• interleukin-1 beta
• receptor activator of nuclear factor-kB ligand (RANKL)
• parathyroid hormone (PTH)
• Disc aging leads to an overall loss of water content and conversion to fibrocartilage. Specifically there is
– decrease in
• nutritional transport
• water content
• absolute number of viable cells
• proteoglycans
• pH
– increase in
• an increase keratin sulfate to chondroitin sulfate ratio
• lactate
• degradative enzyme activity
• density of fibroblast-like cells
– fibroblast-like cells reside in the annulus fibrosus only
– no change in
• absolute quantity of collagen
11. Spectrum of changes(Kirkaldy Willis Concept)
Internal disc disruption
Disc herniation
Intervertebral space decrease
Overloading of facet joints, ligamentous instability
Instability of motion segment
Degenerative spondylolisthesis
Attempt to stabilise by formation of osteophytes and ligaments hypertrophy
Spinal stenosis
Adult spinal deformity
12. Etiology of Intervertebral disc degeneration
Repetitive mechanical activities – Frequent bending, twisting, lifting, and other similar
activities without breaks and improper stretching
Living a sedentary lifestyle – more prone to herniated discs because the muscles that
support the back and neck weaken, which increases strain on the spine.
Traumatic injury to lumbar discs- commonly occurs when lifting while bent at the
waist, rather than lifting with the legs while the back is straight.
Obesity – overloading the motion segment.
Poor posture – Improper spinal alignment
Tobacco abuse – toxins reduces the disc’s ability to absorb nutrients, which results in the
weakening of the disc.
Mutation- in genes coding for proteins involved in the regulation of the extracellular
matrix, such as MMP2 and THBS2,
13. Cellular and Biochemical Changes of the
Intervertebral Disc
Decrease proteoglycan
content.
Loss of negative charged
proteoglycan side chain.
Water loss within the
nucleus pulposus.
Decrease hydrostatic
property.
Loss of disc height.
Uneven stress
distribution on the annulus.
19. Concentric tears :
circumferential lesions, involves
outer layers of the annular wall.
Radial tears:
characterized by an annular tear
which permeates from the deep central part of
the disc (nucleus pulposus) and extends
outward toward the annulus, in either a
transverse or cranial-caudal plane.
Transverse tears:
also known as “peripheral tears” or “rim
lesions,” are horizontal ruptures of fibers, near
the insertion in the bony ring apophyses.
ANNULAR TEARS
20.
21. L4-L5 CT diskogram
demonstrating a large left
posterolateral radial anular tear
associated with a left foraminal and
extraforaminal herniaton
22. Herniated discs in the cranio-caudal
(vertical) direction through a break in
one or both of the vertebral body
endplates are referred to as
“intravertebral herniations” (also
known as Schmorl’s nodes).
They are often surrounded by reactive
bone marrow changes.
Nutrient vascular canals may leave
scars in the endplates, which are weak
spots representing a route for the
early formation of intrabody nuclear
herniations
INTRAVERTEBRAL HERNIATIONS
23. PROLAPSED INTERVERTEBRAL DISC
• Mostly seen in lumbar region followed by cervical
region.
• Affects young adults 30-40 years who still have
relatively maintained disc height.
• Male:female ratio 3:1
• 95% involves L4-5 and L5-S1(most common)
• Herniates through the postero-lateral corner of annulus
fibrosus(thin region)
• Most commont causes:
– Sudden violent trauma (sports injuries)
– Less severe trauma in degenerated annulus(lifting,
bending, coughing, sneezing etc)
24. Anatomic classification
Disc protrusion: the herniated portion of the disc covered
with a thin layer of annulus
Disc extrusion: disc material herniated through annulus but
remains continuous with disc space
Disc sequestration: the disc fragment herniates through the
annulus and loses contact with the originating disc space
25. Classification based on the location of
the disc herniation
• Posterolateral/paracentral prolapse:
– Commonest
– PLL weakest in this area
– Herniated disc impinges on the traversing
nerve roots(e.g the L5 nerve root in L4-5
disc prolapse)
• Central prolapse:
– may present with back pain only or Cauda-
equina(severe cases)
• Foraminal/extra foraminal/far lateral
herniation:
– Less common
– The herniated disc impinges on the exiting
nerve roots
(e.g. L4 nerve root in L4-5 level)
26. Clinical features: History
• History of episode of trauma
• Radicular pain (buttock and thigh pain, extending below the knee
following the distribution of the involved nerve roots)
• aggravated by flexion, sitting, straining, sneezing, cough
• decreased by rest, especially in the semi-Fowler position
• Other symptoms:
– Weakness Corresponding to level of neurological involvement
– Paraesthesia in dermatomal distribution
– Cauda equina
• Natural course of symptomatic PIVD is slow resolution of
symptoms over 6-8 weeks period in 80% of cases
27. Cauda Equina syndrome
• Emergency
– Aggressive evaluation and management
– Large central herniation
• Most consistent symptoms(Tay & Chacha)
– saddle anesthesia
– bilateral ankle areflexia
– bladder symptoms
• Other symptoms-
– numbness and weakness in both legs,
– rectal pain,
– numbness in the perineumBowel
disturbances
28. Clinical Features- Signs
• Antalgic gait
– Affected hip more
extended and knee more
flexed than normal side
• Trendelenberg gait (L5
nerve root)
• List
– abrupt planar shift
– Axillary disc –same side
– Shoulder disc- opposite
side
• Thigh and calf muscle
wasting
• Loss of lumbar lordosis
• Paraspinal spasm- central
furrow sign
29. Provocative tests
– straight leg raise
• a tension sign for L5 and S1 nerve root
• technique
– can be done sitting or supine
– reproduces pain and paresthesia in leg at 30-70 degrees hip flexion
• sensitivity/specificity
– most important and predictive physical finding for identifying who is a good
candidate for surgery
– contralateral SLR
• crossed straight leg raise is less sensitive but more specific
– Lesegue sign
• SLR aggravated by forced ankle dorsiflexion
– Bowstring sign
• SLR aggravated by compression on popliteal fossa
– Kernig test
• pain reproduced with neck flexion, hip flexion, and leg extension
– Naffziger test
• pain reproduced by coughing, which is instigated by lying patient supine and
applying pressure on the neck veins
– Milgram test
• pain reproduced with straight leg elevation for 30 seconds in the supine position
40. Clinical Features- Red Flags
• Extremes of age (<15yr , >55yr)
• Neurological deficits
• Fever
• Unexplained weight loss(10lb in 6months)
• Malaise
• Rest pain/ night pain
• Significant trauma
• Drug and alcohol abuse
41. Non Organic Signs Of Waddell
Described by Waddel in post op
patients
1. Non anatomic tenderness
2. Simulation sign
3. Distraction sign
4. Regional sensory or motor
disturbance
5. Overreaction(most
sensitive)
45. X ray views
• AP and Lateral views
• Oblique views
– Spondylolisthesis and lysis
– Hypertrophic changes around foramina in cervical spine
• Lateral flexion/ extension views
• Ferguson View
– 20 degrees caudocephalic AP
– fifth root compression by a large transverse process of the L5 vertebra
against the ala of the sacrum.
• Angled caudal views
– facet or laminar pathological conditions.
46. X ray- Signs of Instability
• Indirect Signs
– Disc space narrowing,
– Sclerosis of end plates
– Osteophytes
– Traction spur
– Vacuum Sign
• Direct signs
– Translational abnormalities on dynamic films
47. Vacuum sign
• radiolucent defect
• presence of nitrogen gas
accumulations in annular
and nuclear degenerative
fissures
• typical central vacuum
phenomenon gas
collection that fills large
neo-cavity occupying
both the nucleus an
annulus.
• indicative of advanced
disc degeneration.
48. CT scan
Advantages:
• provides superior imaging of cortical and trabecular bone
compared with MRI.
• It provides contrast resolution and identify root compressive
lesions such as disc herniation.
• differentiate between bony osteophyte from soft disc.
• diagnose foraminal encroachment of disc material due to its
ability to visualize beyond the limits of the dural sac and root
sleeves.
Limitations
• cannot differentiate between scar tissue and new disc
herniation
• does not have sufficient soft tissue resolution to allow
differentiation between annulus and nucleus
49. Investigations- MRI
• Most accurate and sensitive modality for the diagnosis
of subtle spinal pathology.
• It allows direct visualization of herniated disc material
and its relationship to neural tissue including intrathecal
contents.
• Advantages over myelography
– No radiation
– Non invasive
– No intrathecal contrast
– More accurate in far lateral disc
– Disc disease of LS junction
– Early disc disease
50. Advantages of MRI over CT
– imaging the disc
– directly images neural structures
– shows the entire region of study (i.e., cervical,
thoracic, or lumbar).
– ability to image the nerve root in the foramen
Limitations
– Showing abnormal anatomy in asymptomatic
patient.
– MRI findings can’t correlate with severity of
symptoms.
51.
52. Indications for MRI
• pain lasting > one month and not
responding to non-operative management
or
• red flags are present
– infection (IV drug user, h/o of fever and chills)
– tumor (h/o or cancer)
– trauma (h/o car accident or fall)
– cauda equina syndrome (bowel/bladder changes)
53.
54. Massive lumbar disc extrusion at L5–S1 in a 44-year-old man. Sagittal (a)
and axial (b) T1-weighted images; sagittal (c) and axial (d) T2-weighted
images. The extruded disc compresses and displaces the right S1 nerve
root. On the sagittal T1-weighted image, the continuity between the
extruding portion and the parent disc can clearly be identified.
55.
56.
57.
58. GADOLINIUM ENHANCED CONTRAST MRI
-Investigation of choice for recurrent disc prolapse
-it allows to distinguish between post surgical
fibrosis(enhances with gadolinium) and recurrent
herniated disc(doesn’t enhance with gadolinium)
59. Myelography
• Unnecessary if clinical and CT or MRI findings are
in complete agreement.
• Indications
– suspicion of an intraspinal lesion,
– patients with spinal instrumentation,
– questionable diagnosis resulting from conflicting clinical
findings and other studies .
– previously operated spine
– marked bony degenerative change that may be
underestimated on MRI
– arachnoiditis
60. Air contrast is used rarely
-Only in situations in which the patient is extremely
allergic to iodized materials
61. Discography- Uses
• Evaluate equivocal abnormality seen
on myelography, CT or MRI
• Isolate a symptomatic disc among
multiple level abnormality
• diagnose a lateral disc herniation
• establish discogenic pain
• select fusion levels
• evaluate the previously operated spine
– distinguish between mass effect
from scar tissue or disc material
62. Electrodiagnostic studies
• Applied when clinical examination and imaging fail
to provide a clear diagnosis or perhaps conflicting
diagnoses
• May include needle electromyelography,
somatosensory evoked potentials or cervical root
stimulation
• May help differentiate primary cervical disorders
from peripheral nerve entrapments syndromes or
pain eminating from the intrinsic shoulder pathology
63. MANAGEMENT
• NON OPERATIVE MANAGEMENT
– 90% respond to conservative management
– Rest in semi-fowler position,ice packs, analgesics,
muscle relaxants, oral steroids, physical therapy
and exercises
– Selective nerve root blocks: transforaminal SNRB
with local anesthetic agent and long acting
corticosteroid combination
– Lumbar epidural steroid injection
67. Bed Rest
• no data to suggest that bed rest alters the
natural history of lumbar disc herniation or
improves outcomes.
• Consensus of 2 days (if used)
Semi Fowlers
Position
69. Excercises
• Better than medical care alone
• Flexion-based isometric exercises appear to
have the most support in the literature
• Offer benefit by decreasing local muscle
spasm and stabilizing the spine.
• Begin when acute pain diminishes
70. Exercises
GENERAL RULES FOR EXERCISE
• Do each exercise slowly. Hold the exercise position for
a slow count of five.
• Start with five repetitions and work up to ten. Relax
completely between each repetition.
• Do the exercises for 10 minutes twice a day.
• Care should be taken when doing exercises that are
painful. A little pain when exercising is not necessarily
bad. If pain is more or referred to the legs the patient
may have overdone it.
• Do the exercises every day without fail.
72. FOR RECOVERY OR SUBACUTE STAGE
EXTENSION CONTROL
HAMSTRING STRETCH
KNEE ROLLS
73. Physical therapy
• TENS
– Trans-cutaneous electrical nerve stimulation
– release of endogenous analgesic endorphins
– Central nervous system process in which a control center is altered to
block transmission of pain
– Deyo RA et al ‘TENS is no different from a placebo’
• Intermittent Pelvic Traction
– Goal- distract the lumbar vertebrae.
– enlargement of the inter-vertebral foramen,
– creation of a vacuum to reduce herniated discs,
– placement of the PLL under tension to aid in reduction of herniated
discs,
– relaxation of muscle spasm,
– freeing of adherent nerve roots
– Does not alter natural history of disease
74. Lifestyle Modifications
• Avoidance of
– Repetitive bending /twisting/ lifting
– Contact sports
– Heavy weights
– 2wheelers, Auto rickshaws
– Soft mattress( Spring, foam)
• Posture training
• Back support while sitting
• Firm mattress (rubberised foam, coir )
75. Intra-discal Electrothermal Therapy
• Low back pain of discogenic origin
• Not useful in radiculopathy
• posterolateral placement of a probe around the inner
circumference of the annulus followed by heating of the
probe.
• Pre Requisites
– Normal neurology
– Negative SLR.
– absence of compressive lesions on MRI
– positive concordant discogram
• Conflicting outcomes requiring refinement of indications
77. SURGICAL MANAGEMENT
• Indications
– persistent disabling pain lasting more than 6 weeks that have failed non-
operative options (and epidural injections)
– progressive and significant weakness
– Cauda-equina syndrome
• Rehabilitation
– patients may return to medium to high-intensity activity at 4 to 6 weeks
• Outcomes: improvement in pain and function greater with surgery
• Positive predictors for good outcome of surgery
– leg pain is chief complaint
– positive straight leg raise
– weakness that correlates with nerve root impingement seen on MRI
– married status
• Negative predictors for good outcome of surgery: worker’s compensation
78. STANDARD DISECTOMY
• Prone position
• With bolsters
• Knee chest position
• Allows abdomen to
hang free,
– minimizing epidural
venous dilation and
bleeding
• Lateral position with
affected side up
79. Salient Points
• Lamina exposed cephalad and caudad
to the level of the herniated disc
• 1-2 sq cm area of lamina removed
exposing dura and nerve root
• Visualise lateral edge of nerve root
• Remove sequestered disc
• Incise Annulus and remove central
and lateral part of nucleus
• Nerve root must freely move 1cm
inferomedially
– Foraminotomy
• Free fat graft to reduce post op
scarring
80. Far lateral microdiskectomy
• indications
– for far-lateral disc herniations
• technique
– utilizes a paraspinal approach of Wiltse
81. Additional Exposure Techniques
• Large disc herniation, lateral recess stenosis or
foraminal stenosis, may require a greater
exposure of the nerve root.
• If the extent of the lesion is known before
surgery, the proper approach can be planned
83. Total Laminectomy
• Reserved for patients
with spinal stenosIs that
are central in nature,
• Occurs typically in cauda
equina syndrome.
84. Facetectomy
• reserved for
– foraminal stenosis
– severe lateral recess stenosis
• If more than one facet is removed, a fusion
should be considered
• Especially in a young, active individual with a
normal disc height at that level.
85. Lumbar Microsurgical Discectomy
• first reported by Williams in 1978
• procedure of choice for herniated lumbar disc
• Decompression of the involved nerve root with
minimum trauma to the adjacent structures.
• Advantages
– decreased operative time,
– Decreased morbidity,
– less loss of blood,
– shorter stay in the hospital,
– earlier return to work.
– Visibility for assistant
87. Microsurgical Lumbar Discectomy
• Requirements
– operating microscope with a 400-mm lens,
– small-angled Kerrison rongeurs of appropriate
length,
– microinstruments,
– combination suction–nerve root retractor
88. Microsurgical Lumbar Discectomy
• Original Guidelines
– Avoidance of laminectomy and of trauma to the
facets,
– Preservation of all extradural fat,
– Blunt perforation of the anulus fibrosus rather than
incision with a scalpel,
– Preservation of healthy, non-herniated intervertebral
disc material,
– Remove only as much disc as is necessary to relieve
the neural elements from visible and palpable
compression.
• New Guidelines
– Subtotal discectomy through an incision, made with
a scalpel,in the anulus fibrosus;
– using bipolar coagulation;
– Removing the medial portion of the facet for
exposure when necessary
89. Percutaneous endoscopic Discectomy
• Mechanically decompress a
herniated lumbar disc via a
posterolateral cannula
• Reduced morbidity
• Reduced hospital stay
• No anaphylactic reactions and
neurological complications
associated with chemonucleolysis
Contraindications
– Presence of sequestered fragments
– Lumbar canal stenosis
– Lumbosacral discs
90. Post op management
• Immediate post op
– Monitor neurology
– Turn in bed , semi fowler position
– Walk with assistance to toilet
– Oral analgesics and muscle relaxants for pain
– Bladder stimulants to assist in voiding
– Discharge- after walking and voiding(day of surgery in
microscopic discectomy)
– minimize sitting and riding in a vehicle to comfort
– Increase walking on a daily basis
– Avoid stooping bending lifting
91. Post op management
• Delayed
– Core strengthening between week 1 & 3
– Lifting bending stooping gradually after 3 weeks
– Long trips avoid for 4-6weeks
– Walking jobs with minimal lifting 2-3weeks
– Prolonged sitting jobs 4-6 weeks
– Heavy labor, long driving 6-8weeks
– Exceptionally heavy manual labour- AVOID
92. COMPLICATIONS
• Infection – Superficial wound
infection , Deep disc space infection
• Thrombophlebitis/ Deep vein
thrombosis
• Pulmonary embolism
• Dural tears may result in
Pseudomeningocoele, CSF leak,
Meningitis
• Postoperative cauda equine lesions
• Neurological damage or nerve root
injury
• Urinary retention and urinary tract
infection
94. Chemo nucleolysis
• Contraindications
– Sequestered disc
– Spinal stenosis
– previous injection of chymopapain
– allergy to papaya or its derivatives;
– Previous surgical treatment of the lumbar spine;
– herniation of more than two discs;
– a rapidly progressive neurological deficit;
– neurogenic dysfunction of the bowel or the bladder, or both;
– spondylohisthesis.
– Spinal tumour
– Pregnancy
– Diabetic neuropathy
95. Chemo nucleolysis
• Complications
– Neurological
• cerebral hemorrhage,
• paraplegia,
• paresis, quadriplegia,
• Guillain-Barre syndrome,
• seizure disorder.
– Anaphylaxis
• Procedure is not in favour now
96. Disc Excision & Arthrodesis
• First suggested by Mixter and Barr
• Indicated for
– Marked segmental instability
– Done when facets are destabilized bilaterally to prevent
Iatrogenic Spondylolisthesis
• Disadvantages of fusion:
– Alters the biomechanics of spine
– Loss of motion and overall shift in the sagittal alignment
– Causes degenerative changes in the adjacent spinal
motion segments
97. Total Disc Replacement
• CHARITE artificial disc (Depuy spine) was the first
implant approved by FDA for total disc
replacement in october 2004.
• Presently, there are only three lumbar disc
prostheses with FDA approval:
– the INMOTION, which is a modification of the Charite
(Depuy Spine, Raynham, MA),
– the ProDisc-L (DePuy Synthes),
– the activL (Aesculap, Center Valley,PA).
• All are approved only for single-level disc replacement.
98. ADVANTAGES OF DISC REPLACEMENT
• Removes the disc/presumed main source of
pain
• Restore disc height----relieves load across the
facet joints----improves the pattern of load
bearing between vertebrae.
• Segmental stability, preservation and
improvement of segmental motion
• Maintain lordosis curve
• Limit disability and early return to work
99. PRE REQUISITES FOR DISC
REPLACEMENT
• Normal facet joints
• Good bone quality(non
osteoporotic)
• No spondylolisthesis or
spinal deformity
• No infection
• Single disc level
The chart on the left demonstrates the five possible severities of the radial angular tear,
grade 0 is a normal disc, where no contrast material (red stuff that was injected into the center of the disc) has leaked from the confines of the nucleus.
grade 1 tear has leaked contrast material but only into the inner 1/3 of the annulus.
The grade 2 tear has leaked contrast from the nucleus into the outer 2/3s of the annulus.
The grade 3 tear has leaked contrast completely through all three zones of the annulus. This tear is now believed to be painful since the outer 1/3 of the disc has many tiny nerve fibers that may now be irritated.
The grade 4 tear further describes the grade 3 tear, in that, now the contract has spread circumferentially around the disc, often resembling a ships anchor.
To qualify as a grade 4 tear tear, the circumferential spread must be greater than 30 degrees. (Pathologically, this represents the merging of a full thickness radial tear with a concentric annular tear.)
The ‘evil’ grade 5 tear has completely ruptured that outer layers of disc and is 'leaking' contract material from the disc into the epidural space. This type of tear is thought to have the ability to induce a severe inflammatory reaction in 'some' peoples posterior neural structures.
which is difficult even with postmyelography CT because the subarachnoid space and the contrast agent do not extend fully through the foramen
Large midline disc herniation (arrow) at the L4-5 level is hypointense on sagittal and axial T2 fast spin echo images (A, B) and is slightly hyperintense relative to the thecal sac on T1 spin echo axial image (C).
Lateral T2-weighted magnetic resonance imaging (MRI) scan demonstrating MIGRATED SEGMENT OF disc material AT LEFT SIDE AND AT RIGHT IMAGE SEGMENT GOING APART FROM DISC IS Sequestration
air injected into the epidural space, increased intrathecal pressure from fluid around the dural sac, and possibly an undetected dural puncture.
It has been shown
to be better than medical care alone
over a six-month period, especially
when the program is medically supervised37,38.
It is also better than chiropractic
manipulation for the treatment of
chronic pain39. Specific types of back
flexion and extension stretching have
been thought to have beneficial effects
for patients with low back pain40. Flexion-
based isometric exercises appear to
have the most support in the literature,
although extension-based exercises,
progressive-resistance exercises, and
dynamic stabilization training are useful
adjuncts30,41. Th
Reduce intradiscal pressure by 20-30%
Put pic of microscope
The procedure is generally performed with the patient
under local anesthesia and prone. A c-arm image-intensifier
is used to identify the proper level and to monitor and
document the course of the operation. A trocar is inserted
eight to nine centimeters from the midline on the symptomatic
side and is advanced into the disc space. If the patient reports radicular pain, the trocar is redirected. When the
trocar is properly positioned, a 4.9-millimeter-diameter cannula
is placed over the trocar and held firmly against the
anulus fibrosus as the trocar is removed. A window is made
in the anulus fibrosus with a cutting instrument that has been
inserted into the cannula, and the fragments of disc are
evacuated with punch forceps and suction’9. In addition to
providing access to the disc space, the posterolateral anular
penetration is believed to decompress the disc space and
perhaps to decrease the chance of a recurrent posterior
herniation’8.