Back pain
Etiology
Anatomical & pathophysiological concepts
Diagnostic approach
Clinical approach
Red flags & yellow flags
Investigations
Back pain in children & elderly
This presentation is a comprehensive summary about all aspects of back pain. Back pain is one of the most common orthopaedic morbidity or orthopedic disability. Sciatica and lumbar disc diseases are common cause of spinal disability. Back pain are divided into Red flags, green flags and yellow flags for quick clinical screening. both treatment, prevention aspects are covered. Spinal anatomy and Biomechanics are covered. Epidemiology and role of various types of spine surgery, microdiscectomy, endoscopic spine surgery are also described.
Back pain
Etiology
Anatomical & pathophysiological concepts
Diagnostic approach
Clinical approach
Red flags & yellow flags
Investigations
Back pain in children & elderly
This presentation is a comprehensive summary about all aspects of back pain. Back pain is one of the most common orthopaedic morbidity or orthopedic disability. Sciatica and lumbar disc diseases are common cause of spinal disability. Back pain are divided into Red flags, green flags and yellow flags for quick clinical screening. both treatment, prevention aspects are covered. Spinal anatomy and Biomechanics are covered. Epidemiology and role of various types of spine surgery, microdiscectomy, endoscopic spine surgery are also described.
Musculoskeletal Health Concerns of the Aging PopulationAllan Corpuz
A lecture on low back pain, osteoarthritis and soft tissue rheumatisms delivered to nurses, nursing attendants and institutional workers at the the Philippine General Hospital
Diffuse idiopathic skeletal hyperostosis (DISH) is a common skeletal process of uncertain etiology found in 12 to 18% of Indian populations above 50 years. The primary manifestations of DISH are calcification and ossification of the spinal ligaments, as well as entheseal ossification within extraspinal sites
Evaluation of Lumbar Spine Disease starts with understanding the clinical back grounds. It starts with good history and physical examination. This is a teaching lecture given twice by Prof. Dr. Mohamed Mohi Eldin, professor of neurosurgery, in the Basic Spine Course, Egyptian Medical Syndicate, Cairo, March 2009 and in 2010.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
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Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
5. Radiographs
What you see
• Bony anatomy and
alignment
• Disc height
Disadvantages
• Radiation
• Nonspecific
– OA changes in most
adults
• Insensitive
– No direct visualisation
of neural and other
nonbony structures
7. Bone scan
What you see
• Bone pathology
– Osteoblastic activity
Disadvantages
• Radiation
• Very nonspecific
• Relatively poor
anatomical resolution
– (Improved with
SPECT; SPECT/CT)
– No direct visualisation
of neural and other
nonbony structures
8. CT
What you see
• Bony anatomy and
alignment
• Cross sectional view
of spinal canal and
foramina
• Disc, thecal sac,
nerve roots
9. CT
What you see
• Bony anatomy and
alignment
• Cross sectional view
of spinal canal and
foramina
• Disc, thecal sac,
nerve roots
Disadvantages
• Radiation
• Nonspecific
– Most adults have
‘findings’
• Poor visualisation of
individual neural
structures and disc
anatomy
10. Radiation doses
Imaging test Effective
dose (mSv)
CXRs Background
exposure
Flying hours
CXR 0.02 1 3 days 4
Lumbar X-ray 1.5 75 6/12 300
Lumbar CT 2-10 100-500 8/12 - 3 years 400 - 1800
Bone scan 6 300 2 years 1200
11. MRI
What you see
• Bony anatomy and
alignment
• Bone pathology
• Multiplanar view of
spinal canal and
foramina
• Disc: hydration and
structure
• Neural structures:
cord, nerve roots
12. MRI
What you see
• Bony anatomy and
alignment
• Bone pathology
• Multiplanar view of
spinal canal and
foramina
• Disc: hydration and
structure
• Neural structures:
cord, nerve roots
Disadvantages
• Availability, cost
• Pacemakers,
claustrophobia
• Nonspecific (too
sensitive)
– Most adults have
‘findings’
13. Appropriate imaging for back pain
• Imaging modalities
• Clinical presentations: classification into 3
broad categories
1. Nonspecific low back pain
2. Back pain associated with radiculopathy
3. Back pain associated with a specific
cause requiring prompt evaluation
• Guidelines
15. Back pain categories
2. Back pain associated with radiculopathy
a) Unilateral acute nerve root compression
(sciatica)
– Leg pain >> back pain
– Disc herniation
b) Unilateral chronic nerve root compression
– Disc herniation or spinal stenosis
c) Bilateral chronic nerve root compression
– Spinal stenosis
– DD vascular claudication
d) Bilateral acute nerve root compression =
‘cauda equina syndrome’
16. Cauda equina syndrome
• Bilateral acute nerve root compression
– Massive disc protrusion/ sequestration
• Sudden onset bilateral leg pain
• Saddle anaesthesia
• Rapidly progressive or severe neurological
deficits
– Motor deficits at >1 level
– Faecal incontinence
– Urinary retention
17. Back pain categories
3. Back pain associated with a specific
cause requiring prompt evaluation
− Cauda equina syndrome
− Cancer
− Vertebral infection
− Vertebral compression fracture
− Ankylosing spondylitis
18. Back pain categories
3. Back pain associated with a specific
cause requiring prompt evaluation
− Cauda equina syndrome
− Clinical scenario
− Cancer
− Vertebral infection
− Vertebral compression fracture
− Ankylosing spondylitis
19. Back pain categories
3. Back pain associated with a specific
cause requiring prompt evaluation
− Cancer
− Hx of Ca + new onset LBP
− Unexplained weight loss +/-
persistent symptoms +/- age > 50
− Vertebral infection
− Vertebral compression fracture
− Ankylosing spondylitis
20. Back pain categories
3. Back pain associated with a specific
cause requiring prompt evaluation
− Vertebral infection
− Fever
− iv drug use
− Recent infection
− Vertebral compression fracture
− Ankylosing spondylitis
21. Back pain categories
3. Back pain associated with a specific
cause requiring prompt evaluation
− Vertebral compression fracture
− Hx of osteoporosis
− Steroid use
− Old age +/- minor trauma
− Ankylosing spondylitis
22. Back pain categories
3. Back pain associated with a specific
cause requiring prompt evaluation
− Ankylosing spondylitis (seronegative
SpA)
− Nonmechanical, inflammatory type of
back pain: morning stiffness; improved
with exercise
− Alternating buttock pain
− Waking at night
− Younger age
23. Appropriate imaging for back pain
• Imaging modalities
• Clinical presentations
• Guidelines
– Multiple: different countries and
associations
– Common theme:
• Triage into 3 broad categories as
described
24. LOW BACK PAIN GUIDELINES
Diagnostic triage
1. Non-specific LBP
2. Radiculopathy
3. Specific LBP
• ‘Red flags’
‘Red Flags’
• Cauda equina syndrome
• Known 10 tumour
• Weight loss
• Severe symptoms, not
settling
• Fever
• Recent infection or Sx
• Osteoporosis
• Steroid use
• Non-mechanical pain
• Child*
25. Back pain in children and adolescents
Presentation Associated Sx DD Ix
Night pain Fever, malaise Tumour, infection X-ray
MRI
Acute pain Radiculopathy
+ve SLR
Disc herniation
Spondylosis
X-ray
MRI
Chronic pain Rigid kyphosis
Morning stiffness
“Scheuermann’s”
Inflammatory arthropathy
X-ray
Pain with extension
Sport: eg rowing
Hamstring tightness Spondylolysis
‘Stress reaction’
X-ray
MRI
Pain + recent onset
scoliosis
Fever, malaise,
+ve SLR
Idiopathic scoliosis
Tumour, infection, syrinx,
disc herniation
X-ray
MRI
Am Fam Phys 2007;76:1669-76
26. LOW BACK PAIN GUIDELINES
• American College of Physicians & American
Pain Society Recommendations
1. Focused Hx and examination to place patients
into 1 of 3 categories
2. No imaging for nonspecific LBP
3. Imaging for LBP + severe or progressive
neurological deficits OR risk factors for specific
cause
4. Imaging for LBP and radiculopathy if candidates
for surgery or epidural injection
Ann Intern Med 2007;147:478-491
27. Diagnostic work-up
Possible cause Imaging Additional studies
Nonspecific LBP None None
Radiculopathy MRI (CT)
Cauda equina MRI
Cancer MRI for known 10; X-ray
for other eg wt loss
ESR
Vertebral infection MRI ESR, CRP
Vertebral compression # X-ray
Ankylosing spondylitis X-ray, incl pelvis (MRI) HLA-B27; ESR, CRP
Ann Intern Med 2007;147:478-491
29. Ineffectiveness of imaging for
nonspecific LBP
• Favourable natural Hx
– Most improve by 4 weeks; unaffected by imaging
• Nonspecificity: loose association between findings
and symptoms
– ‘Abnormalities’ or normal aging?
• Potential harms:
– Radiation
– ‘Labelling’
– Incidental findings
Ann Intern Med 2011;154:181-190
30.
31. • 85 year old female
• Severe acute on chronic mechanical
back pain
– Can’t sleep
– Limited walking to only a few steps
• Spontaneous onset
• No known trauma
Radiograph (X-ray)
44. • 62 year old male
• Severe low back pain of rapid onset
• Febrile and unwell
• 4 weeks ago underwent abdominal
surgery for perforated diverticulitis
MRI